Download or read book The Chemistry of Lactams written by M.I. Page and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is over sixty years since Alexander Fleming observed antibiosis between a Penicillium mould and bacterial cultures and gave the name penicillin to the active principle. Although it was proposed in 1943 that penicillin (1) contained a tJ-Iactam ring, this was not generally accepted until an X-ray crystallographic determination of the structure had been completed. RCONH )=r)
Download or read book The Chemistry and Biology of Beta Lactams written by Daniel Zerong Wang and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This new volume, The Chemistry and Biology of Beta-Lactams, provides the most updated information about beta-lactams relating to both the pharmaceutical industry and synthetic chemistry. It provides valuable information regarding antibiotic activities as well as chemical reactivities of beta-lactams, which are important because they are commonly applied as antibiotics in the treatment of bacterial infections. Presenting the most up-to-date literature information on beta-lactams, the volume provides comprehensive coverage of most of the known beta-lactam antibiotics with both structural and biological information, antibiotic mechanisms, self-defense mechanisms of bacteria, nearly all known synthetic methods for the preparation of beta-lactams, and possible reactions in which beta-lactams can participate. Key features: • Provides the most comprehensive collection of beta-lactam antibiotics (up to 269 molecules) with chemical structures, CAS number, IUPAC names and associated biological activities • Offers a comprehensive collection of beta-lactamase databases, where the features of each database have been described • Explains the self-defense mechanisms of bacteria for surviving, including the formation of biofilm and conversion into L-form, as well as secretion of beta-lactamase to deactivate the beta-lactam antibiotics • Provides a comprehensive survey on the synthetic methods to make beta-lactams • Gives all of the possible reactions involving beta-lactams as the starting materials • Surveys over 1000 research works and includes all available DOI information The important information provided here will be a valuable resource on the antibiotic activities as well as chemical reactivities of beta-lactams for researchers and scientists, faculty, and advanced students, as well as for industry professionals working in medicinal and pharmaceutical chemistry, organic chemistry, organic synthesis, heterocycles, proteins and peptides."--
Download or read book The Chemistry and Biology of Beta Lactams written by Zerong Wang and published by CRC Press. This book was released on 2023-05-12 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides the most comprehensive collection of beta-lactam antibiotics (up to 269 molecules) with chemical structures, CAS number, IUPAC names and associated biological activities Offers a comprehensive collection of beta-lactamase databases, where the features of each database have been described Explains the self-defense mechanisms of bacteria for surviving, including the formation of biofilm and conversion into L-form, as well as secretion of beta-lactamase to deactivate the beta-lactam antibiotics Provides a comprehensive survey on the synthetic methods to make beta-lactams Gives all of the possible reactions involving beta-lactams as the starting materials Surveys over 1000 research works and includes all available DOI information
Download or read book Chemistry and biology of beta lactam antibiotics written by Marvin Gorman and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Chemistry and Biology of B lactams written by Daniel Zerong Wang and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This new volume, The Chemistry and Biology of Beta-Lactams, provides the most updated information about beta-lactams relating to both the pharmaceutical industry and synthetic chemistry. It provides valuable information regarding antibiotic activities as well as chemical reactivities of beta-lactams, which are important because they are commonly applied as antibiotics in the treatment of bacterial infections. Presenting the most up-to-date literature information on beta-lactams, the volume provides comprehensive coverage of most of the known beta-lactam antibiotics with both structural and biological information, antibiotic mechanisms, self-defense mechanisms of bacteria, nearly all known synthetic methods for the preparation of beta-lactams, and possible reactions in which beta-lactams can participate"--
Download or read book Chemistry and Biology of Beta lactam Antibiotics The biology of lactam antibiotics written by Robert B. Morin and published by . This book was released on 1982 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Activity Based Protein Profiling written by Stephan A. Sieber and published by Springer Science & Business Media. This book was released on 2012-02-21 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: ABPP Methodology: Introduction and Overview, by Matthew B. Nodwell und Stephan A. Sieber Activity-Based Protein Profiling for Natural Product Target Discovery, by Joanna Krysiak und Rolf Breinbauer Photoaffinity Labeling in Activity-Based Protein Profiling, by Paul P. Geurink, Laurette M. Prely, Gijs A. van der Marel, Rainer Bischoff und Herman S. Overkleeft Application of Activity-Based Protein Profiling to the Study of Microbial Pathogenesis, by William P. Heal und Edward W. Tate Functional Analysis of Protein Targets by Metabolomic Approaches, by Yun-Gon Kim und Alan Saghatelian
Download or read book Chemistry and Biology of Beta lactam Antibiotics written by Robert B. Morin and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemistry and Biology of Beta Lactams written by Bimal Krishna Banik and published by . This book was released on 2024-10-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery and synthesis of penicillin, many other families of β-lactam antibiotics have been realized and their extensive use worldwide continues to be a forefront line of action against infectious pathogens. Due to their medicinal activity and potential use as synthetic starting materials, studies on beta-lactams have increased.
Download or read book Chemistry and Biology of B lactam Antibiotics written by Robert B. Morin and published by . This book was released on 1982 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemistry and Biology of Beta lactam Antibiotics Nontraditional lactam antibiotics written by Robert B. Morin and published by . This book was released on 1982 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemistry and Biology of lactam Antibiotics The biology of lactam antibiotics written by Robert B. Morin and published by . This book was released on 1982 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis of Lactam Antibiotics written by Alle Bruggink and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, beta-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth scientific approaches to biocatalysis and biocatalyst development including enzyme kinetics, enzyme crystal studies and semi-rational enzyme mutations are also presented. Metabolic pathway analysis and modeling of fermentation process are treated as well as molecular precision in synthetic approaches to beta-lactams, their precursors and derivatives. Process technology studies including new reactor concepts, possible short-cut routes and improved down-stream-processing methods complete a broad view on the scope and limitations of the presently developed industrial processes including an intriguing insight into future process possibilities. This book represents an excellent case study on the transformation of traditional, stoïchiometric, organic synthesis and classical fermentations into modern (bio-) catalysis and biosynthesis based on insights in metabolic pathways and enzyme actions.
Download or read book The Chemistry of beta lactams written by Michael I. Page and published by . This book was released on 1992 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Beta Lactams written by Bimal K. Banik and published by Springer. This book was released on 2017-05-11 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
Download or read book Recent Advances in the Chemistry and Biology of beta lactams and beta lactam Antibiotics written by G. I. Georg and published by . This book was released on 1993 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Recent Advances in the Chemistry and Biology of Beta lactams and Beta lactams Antibiotics written by Gunda I. Georg and published by . This book was released on 1993 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt:
