Download or read book The Chemical Languages of the Nervous System written by Josef Donnerer and published by Karger Medical and Scientific Publishers. This book was released on 2006-01-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurochemical transmission accounts for the majority of information transfer both in the central and peripheral nervous system. The initial findings centred around the experimental work of the two Nobel Prize winners Sir Henry H. Dale and Otto Loewi as well as Wilhelm Feldberg. Their historical findings opened the door to further investigations and extended the list of neurotransmitters to many others such as amino acids, peptides, purines and nitric oxide. In the first part, the publication provides fascinating insights into the life of the three scientists. Their personality and scientific approach are presented through autobiographical sketches and personal memories by authors. Various comments and details of the atmosphere in the laboratory complete the picture of the conditions at the time. The second part is dedicated to the history of the substances, such as neurotransmitters, their antagonists and analogues. The stories of these substances are presented to the reader in a succinct way, including many anecdotes and unusual events on the way to their therapeutic application. Contents Preface Introduction Otto Loewi Otto Loewi Introductory Remarks Autobiographic Sketch. By O. Loewi Otto Loewi 1873-1961. By H.H. Dale Otto Loewi. By F. Brucke Loewi's Time in Graz Comment on Loewi's Dream An Overlooked Parallel to Kekule's Dream: The Discovery of the Chemical Transmission of Nerve Impulses by Otto Loewi. By U. Weiss and R.A. Brown The Loewi Family's Way to the New World Comment on the Film Nobelpreistrager Otto Loewi Henry Hallett Dale Henry Hallett Dale Introductory Remarks Henry Hallett Dale 1875-1968. By W. Feldberg Fifty Years after the Nobel Prize Award to H.H. Dale and Otto Loewi. By G.B. Koelle Religious Reflections of Dale and Loewi Wilhelm Feldberg Wilhelm Feldberg Introductory Remarks The Early History of Synaptic and Neuromuscular Transmission by Acetylcholine: Reminiscences of an Eye Witness. By W. Feldberg From the History of Scientists to that of Neurotransmitters A Substance Isolated from Brain, Synthesized and Called Neurin: Acetylcholine Adrenaline, Noradrenaline and Dopamine: The Catecholamines Enteramine and Serotonin: Two Names and Three Functions of 5-Hydroxytryptamine Histamine: One Substance and Three Functions The Amino Acid Transmitter Family A Cloud of Peptides Substance P Calcitonin Gene-Related Peptide Neuropeptide, Galanine and Vasoactive Intephinal Polypeptide Opioid Peptides Nitric Oxide ATP and Adenosine Peripheral Neurogenic Stimulators Neurotransmission in the Central Nervous System From Transmitter to Receptor: Progress within 50 Years.
Download or read book Handbook of Neurochemistry written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anyone who has any contact with mental patients, old or young, or their families, or just visits a mental hospital or school for the retarded, is aware of the tremendous suffering caused by malfunctioning of the brain. The func tion of no other organ is so crucial for our everyday life, our proper func tioning, indeed our happiness, and no other illness causes as much anguish to patients or their families as mental illness. It is surprising and sad, therefore, how little effort has been devoted to research in this area; more so because such research is the only hope to ameliorate this suffering, or, to speak in the language of politics or economics, to decrease the enormous sums that we spend on trying to help our patients, with what is must generally be agreed are the most primitive and inadequate methods of treatment. Clearly, since functions of the brain are vital not only in illness, but in health, pathology is not the only area of concern to neurochemists, but it is an area that urgently needs neurochemical contributions. Progress in this field has been slower than in other areas of neurochemistry, and it seems that solutions in this field are very elusive. The reason for this is that the experimental approach is especially difficult in conditions specific for humans, or specific for complex behavior.
Download or read book Alterations of Chemical Equilibrium in the Nervous System written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been recognized for more than a thousand years that the function of the brain, like the function of the other organs of the body, is determined by its physical, chemical, and biological properties. Evidence that even its highest functions could be explained by these properties was gathered only in recent years, however; these findings, which clearly have to be confirmed by a great deal of further experimental evidence, indicate that most, if not all, of the functions of the brain are based on its bio chemical and biophysical mechanisms. This at first hearing may sound rather simple, but the ability to understand learning, emotion, perhaps even creativity, on biological terms may well be the most important scientific discovery of all time. Few pieces of knowledge can influence our future health and well-being to the degree that understanding of mental mechanisms will. It has been clearly shown in many ways in the previous volumes of this Handbook that from the biochemical or neurochemical point of view the brain is one of the most active organs. The brain seems stable and in some respects permanent; this is evidence not of inactivity but of carefully controlled homeostasis, of dynamic rather than static equilibrium, with most components undergoing metabolic alterations.
Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structural Elements of the Nervous System written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurochemistry, having the objective of elucidating biochemical processes subserving nervous activity, emerged as an application of chemistry to the of neurobiological problems as a post-World War II phenomenon. investigation However, only in the last 40 years has the chemical community recognized neurochemistry as a distinct, if hybrid, discipline. During this period great strides have been made. However, recently neurochemistry, along with neu rophysiology, neuropharmacology, neuroanatomy, and the behavioral sci ences, has emerged to form neuroscience, a new community of scientists with its own national society, journals, and meetings. Actually, this recently formed hybrid, neuroscience, is in the process of merging with another well-established discipline, molecular genetics (frequently called molecular biology, and itself a hybrid), which appears to have sufficient hybrid vigor to form yet a new community of scientists, which, for want of a more imaginative term, has been called molecular genetic neuroscience. Clearly, advantages resulting from such mergers or hybridizations accrue not only from the merging discipline (neurochemistry in this case) to the new community (molecular genetic neuroscience), but also in the reverse direction. This Foreword will be concerned primarily with examples of this latter process.
Download or read book Biochemistry of Characterised Neurons written by Neville N. Osborne and published by Pergamon. This book was released on 1978 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Characterised Neurons provides a report on the progress made in the analysis of the biology of specific neurons in the central nervous system. This book emphasizes the biochemical, morphological, and functional aspects of characterized neurons, including ways and sophisticated techniques of isolating them. This publication is divided into 11 chapters. The first chapter evaluates the relevance of working with single neurons. Chapters 2 to 6 discuss specific, characterized, invertebrate neurons containing one of the putative neurotransmitter substances. Chapter 7 deals with the b ...
Download or read book Chemical Transmission in the Mammalian Central Nervous System written by Charles H. Hockman and published by . This book was released on 1976 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Understanding The Brain And Its Development A Chemical Approach written by Harun K M Yusuf and published by World Scientific Publishing Company. This book was released on 1992-11-20 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of brain functions at the molecular level has been one of the greatest challenges for man. Up to now, the basis of its most important functions, including the development of consciousness and personality, and the mechanism of learning and memory, remains unknown. However, the pace of discovery at the morphological, cellular, neurophysiological and molecular levels of brain functions has been quite rapid in the past decades. Neuroscience has therefore been an over-advancing and extremely fascinating field of research which has made a significant contribution to our understanding of brain structure, chemistry and function. This book gives a concise synopsis of our present day knowledge of the basic chemical principles of how the brain works and how the brain develops. It is quite an intelligible approach to ordering the tremendous amount of knowledge accumulated so far in various research fields, particularly neurochemistry. Special emphasis has been given to the chemical language of many aspects of brain development as related to morphology and function. The final part is devoted to the plasticity of the brain and the impact of malnutrition and environment in early life on the development of mental functions. Particularly valuable are the many references to original literature, especially when controversial issues are discussed.The book is well written in an easily understandable manner and would be of great help to all students and scientists interested in the extensive and demanding field of neuroscience.
Download or read book Chemical Communication Within the Nervous System and Its Disturbance in Disease written by Anthony Taylor and published by Pergamon. This book was released on 1978 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structural Neurochemistry written by Abel Lajtha and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 601 pages. Available in PDF, EPUB and Kindle. Book excerpt: That chemicals (although not always called by this name) affect the brain and its functions, such as behavior, has been known for thousands of years. It is therefore surprising that the concept that chemical mechanisms are at least partially responsible for the complex functions of the brain is so recent. Investigation of the closely interlinked biophysical and biochemical proper ties of the nervous system has achieved many notable successes in recent years and is the most exciting development in 20th-century science. Although all the morphology, the activity, and the alteration of the brain, whether bioelectric, biochemical, pathological, or structural, constitute an organic and indivisible whole, the ambition of the Handbook is to look at only a few aspects of this whole and to focus the discussions on the experi ments that the neurochemists have performed. Neurochemical study of the nervous system has, perhaps of necessity, gone through several phases: the first phase was more analytical and in volved study of the composition of the tissue; the second, more recent phase clarified many of the metabolic sequences that occur in this tissue. Clearly, both were essential, but they showed that additional approaches are neces sary. The present phase seems to be the study of control processes; present interest focuses on what determines, in a qualitative and quantitative fashion, the processes occurring in the nervous system. Perhaps the next phase will be the study of function, the study of the final stage of integration.
Download or read book The Human Nervous System written by Charles R. Noback and published by Springer Science & Business Media. This book was released on 2005 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this work, the authors integrate three major basic themes of neuroscience to serve as an introduction and review of the subject.
Download or read book Languages of the Brain written by Karl H. Pribram and published by . This book was released on 1981 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Download or read book Brain Architecture Understanding the Basic Plan written by and Director NIBS Neuroscience Program University of Southern California Larry W. Swanson Milo Don and Lucille Appleman Professor of Biological Sciences and published by Oxford University Press, USA. This book was released on 2002-10-23 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Depending on your point of view the brain is an organ, a machine, a biological computer, or simply the most important component of the nervous system. How does it work as a whole? What are its major parts and how are they interconnected to generate thinking, feelings, and behavior? This book surveys 2,500 years of scientific thinking about these profoundly important questions from the perspective of fundamental architectural principles, and then proposes a new model for the basic plan of neural systems organization based on an explosion of structural data emerging from the neuroanatomy revolution of the 1970's. The importance of a balance between theoretical and experimental morphology is stressed throughout the book. Great advances in understanding the brain's basic plan have come especially from two traditional lines of biological thought-- evolution and embryology, because each begins with the simple and progresses to the more complex. Understanding the organization of brain circuits, which contain thousands of links or pathways, is much more difficult. It is argued here that a four-system network model can explain the structure-function organization of the brain. Possible relationships between neural networks and gene networks revealed by the human genome project are explored in the final chapter. The book is written in clear and sparkling prose, and it is profusely illustrated. It is designed to be read by anyone with an interest in the basic organization of the brain, from neuroscience to philosophy to computer science to molecular biology. It is suitable for use in neuroscience core courses because it presents basic principles of the structure of the nervous system in a systematic way.
Download or read book The Naked Neuron written by Rhawn Joseph and published by Springer. This book was released on 1993-08-21 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Still, it marked a monumental and world altering development, since it would become the building block of the brain. The naked neuron generated a revolutionary change resulting in a greater complexity and subtlety of thought. Dr. Joseph vividly depicts how neurons conferred on early humans advanced powers of mental and sensory acuity, including the gift of remembering one's past and contemplating the future. Although humans possess much of the same ancient brain tissue as our fellow primates, Dr. Joseph reveals to us the singular features of the human brain that have enabled humans uniquely to develop complex, spoken language. He holds us spellbound, revealing that although the new and old brain tissue are couched within the same brain, each often has difficulty understanding the impulses and language of the other. This ground-breaking book draws on Dr.
Download or read book Concepts of Biology written by Samantha Fowler and published by . This book was released on 2018-01-07 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.
