Download or read book The Castro Gene written by Todd Buchholz and published by . This book was released on 2007-05-15 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Castro Gene is seamless, suspenseful and shocking. After killing a man in the ring, Luke Braden quits boxing. While toiling as a security guard and yearning to reinvent himself, Luke is swept up into the high-flying domain of Paul Tremont. Tremont, the hottest hedge fund hand around, has a penchant for the dramatic and a disquieting need to control. Being Tremont's protege has its perks-Luke trades in his ratty basement apartment for a penthouse view, his gym clothes for designer suits. But there are strings attached, and Tremont is pulling those strings. Why does Tremont need a washed-up boxer? The answer lies not in what Luke is, but who he is. Luke Braden is the only man who can execute Tremont's diabolical scheme. Fidel Castro risks one last trip to the U.S., and one man will be forced to stand in his way. Luke Braden is in for the fight of his life - or the fight for his life. Intricately plotted with unexpected twists and breathtaking turns, The Castro Gene is a knockout.
Download or read book Blueprint with a new afterword written by Robert Plomin and published by MIT Press. This book was released on 2019-07-16 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: A top behavioral geneticist makes the case that DNA inherited from our parents at the moment of conception can predict our psychological strengths and weaknesses. In Blueprint, behavioral geneticist Robert Plomin describes how the DNA revolution has made DNA personal by giving us the power to predict our psychological strengths and weaknesses from birth. A century of genetic research shows that DNA differences inherited from our parents are the consistent lifelong sources of our psychological individuality—the blueprint that makes us who we are. Plomin reports that genetics explains more about the psychological differences among people than all other factors combined. Nature, not nurture, is what makes us who we are. Plomin explores the implications of these findings, drawing some provocative conclusions—among them that parenting styles don't really affect children's outcomes once genetics is taken into effect. This book offers readers a unique insider's view of the exciting synergies that came from combining genetics and psychology. The paperback edition has a new afterword by the author.
Download or read book The Gene Wars written by Robert M. Cook-Deegan and published by W. W. Norton & Company. This book was released on 1994 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cook-Deegan, a former director of the Biomedical Ethics Advisory Committee of the US Congress and an advisor to the National Center for Human Genome Research, gives a firsthand account of the struggle to launch the Human Genome Project. Using primary documents and interviews, Cook-Deegan explains scientific details, chronicles the origins of the project, covers the conflicts and partnerships between the organizations involved, and examines ethical, legal, and social issues of DNA research. Includes bandw photos. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Introduction to Forensic DNA Evidence for Criminal Justice Professionals written by Jane Moira Taupin and published by CRC Press. This book was released on 2013-06-20 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of DNA profiling in forensic cases has been considered the most innovative technique in forensic science since fingerprinting, yet for those with limited scientific knowledge, understanding DNA enough to utilize it properly can be a daunting task. Introduction to Forensic DNA Evidence for Criminal Justice Professionals is designed for nonscientific readers who need to learn how to effectively use forensic DNA in criminal cases. Written by a forensic scientist world renowned for her expertise in clothing examination, the book provides a balanced perspective on the weight of DNA evidence. Going beyond a simple explanation of the methodology, it arms attorneys and other criminal justice professionals with knowledge of the strengths and limitations of the evidence, including the danger in relying on DNA statistical probabilities in the determination of guilt. The book covers the most common DNA methods used in criminal trials today—nuclear DNA short tandem repeat (STR) techniques, mitochondrial DNA, and Y-STR profiling. It helps prosecutors know when to emphasize DNA evidence or proceed with trial in the absence of such evidence. It assists defense lawyers in knowing when to challenge DNA evidence and perhaps employ an independent expert, when to focus elsewhere, or when to secure the advantage of an early guilty plea. By imparting practical and theoretical knowledge in an accessible manner, the book demystifies the topic to help both sides of the adversarial system understand where DNA evidence fits within the context of the case.
Download or read book Encyclopedia of Evolutionary Biology written by and published by Academic Press. This book was released on 2016-04-14 with total page 2138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Evolutionary Biology, Four Volume Set is the definitive go-to reference in the field of evolutionary biology. It provides a fully comprehensive review of the field in an easy to search structure. Under the collective leadership of fifteen distinguished section editors, it is comprised of articles written by leading experts in the field, providing a full review of the current status of each topic. The articles are up-to-date and fully illustrated with in-text references that allow readers to easily access primary literature. While all entries are authoritative and valuable to those with advanced understanding of evolutionary biology, they are also intended to be accessible to both advanced undergraduate and graduate students. Broad topics include the history of evolutionary biology, population genetics, quantitative genetics; speciation, life history evolution, evolution of sex and mating systems, evolutionary biogeography, evolutionary developmental biology, molecular and genome evolution, coevolution, phylogenetic methods, microbial evolution, diversification of plants and fungi, diversification of animals, and applied evolution. Presents fully comprehensive content, allowing easy access to fundamental information and links to primary research Contains concise articles by leading experts in the field that ensures current coverage of each topic Provides ancillary learning tools like tables, illustrations, and multimedia features to assist with the comprehension process
Download or read book The Secret Fidel Castro written by Servando Gonzalez and published by InteliNet/InteliBooks. This book was released on 2001 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Secret Fidel Castro is neither a history of the Cuban revolution nor a biography of Fidel Castro. The book was written following what intelligence services call a CPP (short for Comprehensive Personality Profile), similar to the ones intelligence services keep on foreign leaders. It focuses on different aspects of Castro's actions and personality which, for some reasons, have been either ignored, misunderstood, or misrepresented. The main thesis of this book is that there are many different Castros. The most widely known is the symbolic, public one, as it has been portrayed in official Cuban propaganda, Castro-friendly biographies, and mainstream American media. But there are also many secret Castros, highly different from the public one. The Secret Fidel Castro focuses on little known aspects of Castro's personality, important in the better understanding of the man and his actions?what really makes him tick.
Download or read book Management of Genetic Syndromes written by Suzanne B. Cassidy and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 1678 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bestselling guide to the medical management of common genetic syndromes —now fully revised and expanded A review in the American Journal of Medical Genetics heralded the first edition of Management of Genetic Syndromes as an "unparalleled collection of knowledge." Since publication of the first edition, improvements in the molecular diagnostic testing of genetic conditions have greatly facilitated the identification of affected individuals. This thorough revision of the critically acclaimed bestseller offers original insights into the medical management of sixty common genetic syndromes seen in children and adults, and incorporates new research findings and the latest advances in diagnosis and treatment of these disorders. Expanded to cover five new syndromes, this comprehensive new edition also features updates of chapters from the previous editions. Each chapter is written by an expert with extensive direct professional experience with that disorder and incorporates thoroughly updated material on new genetic findings, consensus diagnostic criteria, and management strategies. Edited by two of the field's most highly esteemed experts, this landmark volume provides: A precise reference of the physical manifestations of common genetic syndromes, clearly written for professionals and families Extensive updates, particularly in sections on diagnostic criteria and diagnostic testing, pathogenesis, and management A tried-and-tested, user-friendly format, with each chapter including information on incidence, etiology and pathogenesis, diagnostic criteria and testing, and differential diagnosis Up-to-date and well-written summaries of the manifestations followed by comprehensive management guidelines, with specific advice on evaluation and treatment for each system affected, including references to original studies and reviews A list of family support organizations and resources for professionals and families Management of Genetic Syndromes, Third Edition is a premier source to guide family physicians, pediatricians, internists, medical geneticists, and genetic counselors in the clinical evaluation and treatment of syndromes. It is also the reference of choice for ancillary health professionals, educators, and families of affected individuals looking to understand appropriate guidelines for the management of these disorders. From a review of the first edition: "An unparalleled collection of knowledge . . . unique, offering a gold mine of information." —American Journal of Medical Genetics
Download or read book Cardiovascular Genetics and Genomics in Clinical Practice written by Donna K. Arnett, PhD and published by Demos Medical Publishing. This book was released on 2014-11-10 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Weighted Numerical Score: 100 - 5 Stars! This is a systematic guide to cardiovascular genetics and genomics from basic concepts to clinical application. It organizes a large volume of information from an active area of research, which holds promise for future discovery. --Doody's Reviews Cardiovascular Genetics and Genomics in Clinical Practice presents clinical cases to illuminate basic concepts of cardiovascular genetics and genomics as practitioners encounter them in day-to-day practice. The unique use of real-world case discussions facilitates the memorization and understanding of basic principles, which can be more readily applied to actual cases. Cardiovascular Genetics and Genomics in Clinical Practice features a step-by-step learning process that begins with an easy-to-understand "primer" of basic scientific concepts regarding cardiovascular genetics and genomics followed by state-of-the-art research and applications for treatment of cardiovascular disorders. Expert clinicians and researchers describe illustrative cases for each topic along with detailed discussions of current scientific understanding and its application in current disease management and treatment. Summaries, key teaching points, and illustrations are highlighted to facilitate quick recall and review. The book will be useful for cardiovascular clinicians in training, board preparation, or as a review for those already in clinical practice. Cardiovascular Genetics and Genomics in Clinical Practice features: Clinical case scenarios to illuminate the basic concepts of cardiovascular genetics and genomics as they are used in daily practice Explanation of fundamental concepts as a foundation for more in-depth understanding Detailed discussions of current scientific knowledge and clinical management The expertise of renowned clinician-scientists in the field Real practical insight for practice
Download or read book Genes Environments and Interactions written by José M Álvarez-Castro and published by Springer Nature. This book was released on 2024-01-18 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic effects are the core concepts from which quantitative genetics and the evolutionary synthesis emerged. The groundbreaking theory of genetic effects was first proposed over a century ago. This book revises that theory, both conceptually and mathematically, and brings it up-to-date. The theory here compiled is supplemented with non-previously-published developments covering the broadest spectrum of simultaneously multiallelic and multilocus architectures with autosomal and sex-linked loci Arbitrary interactions (dominance, gene-gene, gene-environment, gene-sex, and parent-of-origin interactions) are accounted for Both effects of allele substitutions from the reference of individual genotypes and in the context of populations are worked out Populations are considered regardless of any departures from equilibrium frequencies (including both departures from Hardy-Weinberg, departures from linkage equilibrium, and non-random associations between/among genes and environments) All developments are derived under the same mathematical framework, so that transformations of genetic effects between different contexts are easily allowed In brief, this book enables novel applications to current empirical paradigms (like gene-mapping and genomic prediction) while adhering to the classical conceptualization of genetic effects and variance decomposition that let quantitative genetics and the evolutionary synthesis flourish. All relevant concepts are carefully clarified and discussed from a historical perspective. The theoretical developments presented in the book are illustrated by built-in cases and applications with real data. Reassuringly, the adequacy of the theory here presented is corroborated based on the fundamentals of model development.
Download or read book Cald of the Long Sun written by Gene Wolfe and published by Macmillan. This book was released on 1995 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third volume in the Book of the Long Sun series. In the very distant future, the inhabitants of a great generation starship, The Whorl, have traveled so long and far that they have forgotten their origins and their destiny. In this world, Patera Silk, a young cleric, has been spoken to by a god and given a mission--to save his church buildings.
Download or read book Hoffa s Man written by Joseph Franco and published by Dell. This book was released on 1989 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is the shocking inside story of Jimmy Hoffa, his powerful Teamsters Union and his underworld operations, as told by one of the men Hoffa trusted most. An electrifying tale . . . a thoroughly provocative, ungilded account.--Boston Herald.
Download or read book Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria written by Frans J. de Bruijn and published by John Wiley & Sons. This book was released on 2016-07-13 with total page 1472 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacteria in various habitats are subject to continuously changing environmental conditions, such as nutrient deprivation, heat and cold stress, UV radiation, oxidative stress, dessication, acid stress, nitrosative stress, cell envelope stress, heavy metal exposure, osmotic stress, and others. In order to survive, they have to respond to these conditions by adapting their physiology through sometimes drastic changes in gene expression. In addition they may adapt by changing their morphology, forming biofilms, fruiting bodies or spores, filaments, Viable But Not Culturable (VBNC) cells or moving away from stress compounds via chemotaxis. Changes in gene expression constitute the main component of the bacterial response to stress and environmental changes, and involve a myriad of different mechanisms, including (alternative) sigma factors, bi- or tri-component regulatory systems, small non-coding RNA’s, chaperones, CHRIS-Cas systems, DNA repair, toxin-antitoxin systems, the stringent response, efflux pumps, alarmones, and modulation of the cell envelope or membranes, to name a few. Many regulatory elements are conserved in different bacteria; however there are endless variations on the theme and novel elements of gene regulation in bacteria inhabiting particular environments are constantly being discovered. Especially in (pathogenic) bacteria colonizing the human body a plethora of bacterial responses to innate stresses such as pH, reactive nitrogen and oxygen species and antibiotic stress are being described. An attempt is made to not only cover model systems but give a broad overview of the stress-responsive regulatory systems in a variety of bacteria, including medically important bacteria, where elucidation of certain aspects of these systems could lead to treatment strategies of the pathogens. Many of the regulatory systems being uncovered are specific, but there is also considerable “cross-talk” between different circuits. Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria is a comprehensive two-volume work bringing together both review and original research articles on key topics in stress and environmental control of gene expression in bacteria. Volume One contains key overview chapters, as well as content on one/two/three component regulatory systems and stress responses, sigma factors and stress responses, small non-coding RNAs and stress responses, toxin-antitoxin systems and stress responses, stringent response to stress, responses to UV irradiation, SOS and double stranded systems repair systems and stress, adaptation to both oxidative and osmotic stress, and desiccation tolerance and drought stress. Volume Two covers heat shock responses, chaperonins and stress, cold shock responses, adaptation to acid stress, nitrosative stress, and envelope stress, as well as iron homeostasis, metal resistance, quorum sensing, chemotaxis and biofilm formation, and viable but not culturable (VBNC) cells. Covering the full breadth of current stress and environmental control of gene expression studies and expanding it towards future advances in the field, these two volumes are a one-stop reference for (non) medical molecular geneticists interested in gene regulation under stress.
Download or read book Conservation Genetics in Mammals written by Jorge Ortega and published by Springer Nature. This book was released on 2020-01-24 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the use of molecular tools to study small populations of rare and endangered mammals, and presents case studies that apply an evolutionary framework to address innovative questions in the emerging field of mammalian conservation genomics using a highly diverse set of novel molecular tools. Novel and more precise molecular technologies now allow experts in the field of mammology to interpret data in a more contextual and empirical fashion and to better describe the evolutionary and ecological processes that are responsible for the patterns they observe. The book also demonstrates how recent advances in genetic/genomic technologies have been applied to assess the impact of environmental/anthropogenic changes on the health of small populations of mammals. It examines a range of issues in the field of mammalian conservation genomics, such as the role that the genetic diversity of the immune system plays in disease protection and local adaptation; the use of noninvasive techniques and genomic banks as a resource for monitoring and restoring populations; the structuring of population by physical barriers; and genetic diversity. Further, by integrating research from a variety of areas – including population genetics, molecular ecology, systematics, and evolutionary and conservation biology – it enables readers to gain a deeper understanding of the conservation biology of mammals that are at increasing risk of extinction at local, regional and global scales. As such, it offers a unique resource for a broad readership interested in the conservation biology of mammals and conservation management strategies to better preserve biodiversity.
Download or read book Key Transitions in Animal Evolution written by Rob Desalle and published by CRC Press. This book was released on 2010-12-07 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tackling one of the most difficult and delicate of the evolutionary questions, this challenging book summarizes the more recent results in phylogenetics and developmental biology that address the evolution of key innovations in metazoans. Divided into three sections, the first considers the phylogenetic issues involving this area of the tree of lif
Download or read book The Hungry Brain written by Stephan J. Guyenet, Ph.D. and published by Flatiron Books. This book was released on 2017-02-07 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Publishers Weekly Best Book of the Year From an obesity and neuroscience researcher with a knack for engaging, humorous storytelling, The Hungry Brain uses cutting-edge science to answer the questions: why do we overeat, and what can we do about it? No one wants to overeat. And certainly no one wants to overeat for years, become overweight, and end up with a high risk of diabetes or heart disease--yet two thirds of Americans do precisely that. Even though we know better, we often eat too much. Why does our behavior betray our own intentions to be lean and healthy? The problem, argues obesity and neuroscience researcher Stephan J. Guyenet, is not necessarily a lack of willpower or an incorrect understanding of what to eat. Rather, our appetites and food choices are led astray by ancient, instinctive brain circuits that play by the rules of a survival game that no longer exists. And these circuits don’t care about how you look in a bathing suit next summer. To make the case, The Hungry Brain takes readers on an eye-opening journey through cutting-edge neuroscience that has never before been available to a general audience. The Hungry Brain delivers profound insights into why the brain undermines our weight goals and transforms these insights into practical guidelines for eating well and staying slim. Along the way, it explores how the human brain works, revealing how this mysterious organ makes us who we are.
Download or read book Understanding Suicide written by Philippe Courtet and published by Springer. This book was released on 2016-03-05 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book international experts address a range of key current issues relating to suicide. The opening chapters discuss nosology, definitions, clinical determinants, and conceptual models of the suicide process and consider the evidence regarding potential biomarkers of suicide risk based on neuroscientific research. Adopting a neo-Durkheimian perspective, the role of various social factors in the genesis of suicidal behavior is then explored in depth. Practical user-friendly tools that facilitate risk assessment by clinicians are provided, and detailed consideration is given to efficient and innovative strategies for the prevention of suicide and the treatment of suicidal behavior, such as psychotherapy, psychopharmacological approaches, and effective organization of care, including surveillance and the use of online tools. The final part of the book focuses on the need for and development of a personalized approach within the field of suicide prevention.
Download or read book Genetics of Familial Hypercholesterolemia New Insight written by Alpo Juhani Vuorio and published by Frontiers Media SA. This book was released on 2021-07-02 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt:
