Download or read book The Bip And Blin Report written by Robert Relic and published by Robert Relic. This book was released on 2021-12-07 with total page 29 pages. Available in PDF, EPUB and Kindle. Book excerpt: This story follows Bip, Blin, and Brani. They are three aliens that travel space using an old alien cruise ship to discover, document and interview different species. While traveling they decide to visit Blin's home planet. After there is a navigation error they end up finding Earth and decide to investigate. Original publish date 12/07/2021 Copyrights owned and Reserved.
Download or read book The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder written by American Psychiatric Association and published by American Psychiatric Pub. This book was released on 2018-01-11 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol use disorder (AUD) is a major public health problem in the United States. The estimated 12-month and lifetime prevalence values for AUD are 13.9% and 29.1%, respectively, with approximately half of individuals with lifetime AUD having a severe disorder. AUD and its sequelae also account for significant excess mortality and cost the United States more than $200 billion annually. Despite its high prevalence and numerous negative consequences, AUD remains undertreated. In fact, fewer than 1 in 10 individuals in the United States with a 12-month diagnosis of AUD receive any treatment. Nevertheless, effective and evidence-based interventions are available, and treatment is associated with reductions in the risk of relapse and AUD-associated mortality. The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder seeks to reduce these substantial psychosocial and public health consequences of AUD for millions of affected individuals. The guideline focuses specifically on evidence-based pharmacological treatments for AUD in outpatient settings and includes additional information on assessment and treatment planning, which are an integral part of using pharmacotherapy to treat AUD. In addition to reviewing the available evidence on the use of AUD pharmacotherapy, the guideline offers clear, concise, and actionable recommendation statements, each of which is given a rating that reflects the level of confidence that potential benefits of an intervention outweigh potential harms. The guideline provides guidance on implementing these recommendations into clinical practice, with the goal of improving quality of care and treatment outcomes of AUD.
Download or read book CMJ New Music Report written by and published by . This book was released on 2003-01-20 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: CMJ New Music Report is the primary source for exclusive charts of non-commercial and college radio airplay and independent and trend-forward retail sales. CMJ's trade publication, compiles playlists for college and non-commercial stations; often a prelude to larger success.
Download or read book Lasso Peptides written by Yanyan Li and published by Springer. This book was released on 2014-10-21 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lasso peptides form a growing family of fascinating ribosomally-synthesized and post-translationally modified peptides produced by bacteria. They contain 15 to 24 residues and share a unique interlocked topology that involves an N-terminal 7 to 9-residue macrolactam ring where the C-terminal tail is threaded and irreversibly trapped. The ring results from the condensation of the N-terminal amino group with a side-chain carboxylate of a glutamate at position 8 or 9, or an aspartate at position 7, 8 or 9. The trapping of the tail involves bulky amino acids located in the tail below and above the ring and/or disulfide bridges connecting the ring and the tail. Lasso peptides are subdivided into three subtypes depending on the absence (class II) or presence of one (class III) or two (class I) disulfide bridges. The lasso topology results in highly compact structures that give to lasso peptides an extraordinary stability towards both protease degradation and denaturing conditions. Lasso peptides are generally receptor antagonists, enzyme inhibitors and/or antibacterial or antiviral (anti-HIV) agents. The lasso scaffold and the associated biological activities shown by lasso peptides on different key targets make them promising molecules with high therapeutic potential. Their application in drug design has been exemplified by the development of an integrin antagonist based on a lasso peptide scaffold. The biosynthesis machinery of lasso peptides is therefore of high biotechnological interest, especially since such highly compact and stable structures have to date revealed inaccessible by peptide synthesis. Lasso peptides are produced from a linear precursor LasA, which undergoes a maturation process involving several steps, in particular cleavage of the leader peptide and cyclization. The post-translational modifications are ensured by a dedicated enzymatic machinery, which is composed of an ATP-dependent cysteine protease (LasB) and a lactam synthetase (LasC) that form an enzymatic complex called lasso synthetase. Microcin J25, produced by Escherichia coli AY25, is the archetype of lasso peptides and the most extensively studied. To date only around forty lasso peptides have been isolated, but genome mining approaches have revealed that they are widely distributed among Proteobacteria and Actinobacteria, particularly in Streptomyces, making available a rich resource of novel lasso peptides and enzyme machineries towards lasso topologies.
Download or read book Psychosis and Schizophrenia in Children and Young People written by National Collaborating Centre for Mental Health (Great Britain) and published by RCPsych Publications. This book was released on 2013 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: These guidelines from NICE set out clear recommendations, based on the best available evidence, for health care professionals on how to work with and implement physical, psychological and service-level interventions for people with various mental health conditions.The book contains the full guidelines that cannot be obtained in print anywhere else. It brings together all of the evidence that led to the recommendations made, detailed explanations of the methodology behind their preparation, plus an overview of the condition covering detection, diagnosis and assessment, and the full range of treatment and care approaches. There is a worse prognosis for psychosis and schizophrenia when onset is in childhood or adolescence, and this new NICE guideline puts much-needed emphasis on early recognition and assessment of possible psychotic symptoms. For the one-third of children and young people who go on to experience severe impairment as a result of psychosis or schizophrenia the guideline also offers comprehensive advice from assessment and treatment of the first episode through to promoting recovery.This guideline reviews the evidence for recognition and management of psychosis and schizophrenia in children and young people across the care pathway, encompassing access to and delivery of services, experience of care, recognition and management of at-risk mental states, psychological and pharmacological interventions, and improving cognition and enhancing engagement with education and employment.
Download or read book The Domain of Language written by Michael D. Fortescue and published by Museum Tusculanum Press. This book was released on 2002 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended as counter-evidence to the perception of Linguistics as the domain of dusty schoolroom grammar, where proponents of one theoretical orientation or the other spend their brief breaks in the playground bashing the others over the head with their favorite abstractions. The discipline may appear to outsiders as fragmented and, worse still, lacking in relevance to the real world outside its gates. The purpose is to show that Linguistics, in all its varied branches, can be entertaining as well as thought-provoking, and that its domain is indeed a coherent one despite all the internecine squabbling. The subject is introduced in an unconventional way as a kind of fable with an historical moral that professional linguists, as well as students, should enjoy as a commentary on the state of the discipline today.
Download or read book Captain Swing written by Eric Hobsbawm and published by Verso Books. This book was released on 2014-08-12 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sir Your name is down amongst the Black hearts in the Black Book and this is to advise you and the like of you, who are Parson Justasses, to make your wills Ye have been the Blackguard Enemies of the People on all occasions, Ye have not yet done as ye ought - Swing In our increasingly mechanized age, the Swing revolts are a timely record of the relationship between technological advance, labour and poverty. With the onset of the Industrial Revolution, capitalism swept from the cities into the countryside, and tensions mounted between agricultural workers and employers. From 1830 on, a series of revolts, known as the "Swing" shook England to its core. Landowners wanting to make their land more profitable started to use machinery to harvest crops, causing widespread misery among rural communities. Captain Swing reveals the background to that upheaval, from its rise to its fall, and shines a light on the people who tried to change the world and save their livelihoods.
Download or read book American Psychiatric Association Practice Guidelines written by American Psychiatric Association and published by American Psychiatric Publishing. This book was released on 1996 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the American Psychiatric Association Practice Guideline series is to improve patient care. Guidelines provide a comprehensive synthesis of all available information relevant to the clinical topic. Practice guidelines can be vehicles for educating psychiatrists, other medical and mental health professionals, and the general public about appropriate and inappropriate treatments. The series also will identify those areas in which critical information is lacking and in which research could be expected to improve clinical decisions. The Practice Guidelines are also designed to help those charged with overseeing the utilization and reimbursement of psychiatric services to develop more scientifically based and clinically sensitive criteria.
Download or read book Biosurfactants written by Gloria Soberón-Chávez and published by Springer Science & Business Media. This book was released on 2010-09-29 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosurfactants, tensio-active compounds produced by living cells, are now gaining increasing interest due to their potential applications in many different industrial areas in which to date almost exclusively synthetic surfactants have been used. Their unique structures and characteristics are just starting to be appreciated. In addition, biosurfactants are considered to be environmentally “friendly,” relatively non-toxic and biodegradable. This Microbiology Monographs volume deals with the most recent advances in the field of microbial biosurfactants, such as rhamnolipids, serrawettins, trehalolipids, mannosylerythritol lipids, sophorolipids, surfactin and other lipopeptides. Each chapter reviews the characteristics of an individual biosurfactant including the physicochemical properties, the chemical structures, the role in the physiology of the producing microbes, the biosynthetic pathways, the genetic regulation, and the potential biotechnological applications.
Download or read book Bone Research Protocols written by Aymen I. Idris and published by . This book was released on 2019 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pantomime written by Karl Toepfer and published by Vosuri Media. This book was released on 2019-08-19 with total page 1320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers perhaps the most comprehensive history of pantomime ever written. No other book so thoroughly examines the varieties of pantomimic performance from the early Roman Empire, when the term “pantomime” came into use, until the present. After thoroughly examining the complexities and startlingly imaginative performance strategies of Roman pantomime, the author identifies the peculiar political circumstances that revived and shaped pantomime in France and Austria in the eighteenth century, leading to the Pierrot obsession in the nineteenth century. Modernist aesthetics awakened a huge, highly diverse fascination with pantomime. The book explores an extraordinary variety of modernist and postmodern approaches to pantomime in Germany, Austria, France, numerous countries of Eastern Europe, Russia, Scandinavia, Spain, Belgium, The Netherlands, Chile, England, and The United States. Making use of many performance and historical documents never before included in pantomime histories, the book also discusses pantomime’s messy relation to dance, its peculiar uses of music, its “modernization” through silent film aesthetics, and the extent to which writers, performers, or directors are “authors” of pantomimes. Just as importantly, the book explains why, more than any other performance medium, pantomime allows the spectator to see the body as the agent of narrative action.
Download or read book Plant Diseases Caused by Dickeya and Pectobacterium Species written by Frédérique Van Gijsegem and published by Springer Nature. This book was released on 2021-01-04 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a detailed review of many different aspects of pathogens, from the effects of single base pair mutations to large-scale control options, bringing into a single volume over 100 years of findings from thousands of researchers worldwide. Diseases caused by soft rot Pectobacteriaceae (SRP) are a major cause of loss to crop, vegetables and ornamental plants worldwide, and have been found on all continents except Antarctica. While different aspects of the SRP have appeared in other books on plant disease, no book, until now, has been dedicated solely to them.
Download or read book Reverse Acronyms Initialisms Abbreviations Dictionary written by and published by . This book was released on 2007 with total page 1580 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Games Diversions of Argyleshire written by Robert Craig Maclagan and published by . This book was released on 1901 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Human Readable Messages written by Mez Breeze and published by . This book was released on 2012-01 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mez does for code poetry as jodi and Vuk Cosic have done for ASCII Art: Turning a great, but naively executed concept into something brilliant, paving the ground for a whole generation of digital artists." (Florian Cramer).
Download or read book Indian Tribes of Washington Territory written by George Gibbs and published by . This book was released on 1967 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Viral Molecular Machines written by Michael G. Rossmann and published by Springer Science & Business Media. This book was released on 2012-02-02 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will contain a series of solicited chapters that concern with the molecular machines required by viruses to perform various essential functions of virus life cycle. The first three chapters (Introduction, Molecular Machines and Virus Architecture) introduce the reader to the best known molecular machines and to the structure of viruses. The remainder of the book will examine in detail various stages of the viral life cycle. Beginning with the viral entry into a host cell, the book takes the reader through replication of the genome, synthesis and assembly of viral structural components, genome packaging and maturation into an infectious virion. Each chapter will describe the components of the respective machine in molecular or atomic detail, genetic and biochemical analyses, and mechanism. Topics are carefully selected so that the reader is exposed to systems where there is a substantial infusion of new knowledge in recent years, which greatly elevated the fundamental mechanistic understanding of the respective molecular machine. The authors will be encouraged to simplify the detailed knowledge to basic concepts, include provocative new ideas, as well as design colorful graphics, thus making the cutting-edge information accessible to broad audience.
