Download or read book The Biochemistry of the Nucleic Acids written by R.L.P. Adams and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the first edition of this book was published in 1950, it predated the publication of the double-helical structure of DNA by three years. It is not, therefore, surprizing that nothing of the original book remains in the current edition. Indeed, such is the pace of change in the field of nucleic acids that less than 50% of material incorporated into the 1986 edition has been retained. The book aims at the advanced undergraduate and at graduates that are undertaking course work or requiring an in-depth background for their research. It also aims to provide the established scientist with a single text that permits updating across the whole field from DNA structure, replication and repair, through gene expression and its control to protein synthesis. Every chapter is accompanied by thorough referencing that enables the reader to evaluate personally the data and methodology that cannot be included in the text. In an attempt to keep this list within bounds, references are limited to about ten per page and, to accommodate the more recent literature, many of the older references have been left out in this latest edition.
Download or read book The Biochemistry of the Nucleic Acids written by R. L. Adams and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: When the first edition of this book was published in 1950, it set out to present an elementary outline of the state of knowledge of nucleic acid biochemistry at that time and it was the first monograph on the subject to appear since Levene's book on Nucleic Acids in 1931. The fact that a tenth edition is required after thirty five years and that virtually nothing of the original book has been retained is some measure of the speed with which knowledge has advanced in this field. As a result of this vast increase in information it becomes increasingly difficult to fulfil the aims of providing an introduction to nucleic acid biochemistry and satisfying the requirements of advanced undergraduates and postgraduates in biochemistry, genetics and molecular biology. We have attempted to achieve these aims by con centrating on those basic aspects not normally covered in the general biochemistry textbooks and by providing copious references so that details of methodology can readily be retrieved by those requiring further information. The first seven editions emerged from the pen of J. N. Davidson who died in September 1972 shortly after completing the seventh edition. The subsequent editions have been produced by various colleagues who have tried to retain something of the character and structure of the earlier editions while at the same time introducing new ideas and concepts and eliminating some of the more out -dated material.
Download or read book Nucleic Acids in Chemistry and Biology written by G Michael Blackburn and published by Royal Society of Chemistry. This book was released on 2015-11-09 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved. Revised and updated Nucleic Acids in Chemistry and Biology 3rd Edition discusses in detail, both the chemistry and biology of nucleic acids and brings RNA into parity with DNA. Written by leading experts, with extensive teaching experience, this new edition provides some updated and expanded coverage of nucleic acid chemistry, reactions and interactions with proteins and drugs. A brief history of the discovery of nucleic acids is followed by a molecularly based introduction to the structure and biological roles of DNA and RNA. Key chapters are devoted to the chemical synthesis of nucleosides and nucleotides, oligonucleotides and their analogues and to analytical techniques applied to nucleic acids. The text is supported by an extensive list of references, making it a definitive reference source. This authoritative book presents topics in an integrated manner and readable style. It is ideal for graduate and undergraduates students of chemistry and biochemistry, as well as new researchers to the field.
Download or read book Nucleic Acids in Chemistry and Biology written by G. Michael Blackburn and published by Irl Press. This book was released on 1996 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of the DNA double helix in 1953, nucleic acids have formed the central theme of much of contemporary molecular science. Nowhere is this more apparent than in the increasing efforts to determine the DNA sequence of the human genome and the development of new diagnostics of genetic disease. Recent sophistication of nucleic acids synthesis has been key to the establishment of the biotechnology industry and our improving knowledge of nucleic acid structures and interactions is noticeably influencing the design of novel drugs.This second and completely revised edition draws on the expertise of the same international group of authors to set the basics of the nucleic acids in the context of the expanding horizons set by modern structural biology, RNA enzymology, drug discovery and biotechnology.
Download or read book The biochemistry of the Nucleic Acids written by J.N. Davidson and published by Elsevier. This book was released on 2012-12-02 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biochemistry of the Nucleic Acids provides an elementary outline of the main biochemical features of nucleic acids and nucleoproteins. The book describes the occurrence and biological functions of nucleic acids, their chemical constituents, and catabolism. This text is organized into 14 chapters and begins with a historical overview, from the discovery of the nucleic acids to their isolation and characterization. The discussion then shifts to bacterial transforming factors and transduction phenomena, along with the genetic function and metabolic stability of DNA, the chemical composition of the cell nucleus, and the Feulgen nucleal reaction. The reader is methodically introduced to the structure and biosynthesis of RNA and DNA; nucleic acids found in viruses; and biosynthesis of mononucleotides. An account of nucleases and related enzymes is also given. A chapter on the precise mechanism by which nucleic acids are broken down in the cell concludes the book. This book is intended for students of biochemistry, chemists, and biologists.
Download or read book Chemistry of Nucleic Acids written by Harri Lönnberg and published by Walter de Gruyter GmbH & Co KG. This book was released on 2024-09-23 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses main aspects of synthesis, hydrolytic stability and solution equilibria of nucleosides, nucleotides and oligonucleotides, as well as synthesis of their structural analogs that are of interest in chemotherapy. In addition, recent achievements in chemistry of catalytic nucleic acids, development of oligonucleotide based drugs and novel strategies for their targeting and delivery are discussed. The central theme always is the correlation of structure and function.
Download or read book The Chemical Biology of Nucleic Acids written by Günter Mayer and published by John Wiley & Sons. This book was released on 2011-06-17 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: With extensive coverage of synthesis techniques and applications, this text describes chemical biology techniques which have gained significant impetus during the last five years. It focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis The Chemical Biology of Nucleic Acids is an essential compendium of the synthesis of nucleic acids and their biological applications for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
Download or read book Nucleic Acids written by Victor A. Bloomfield and published by Sterling Publishing Company. This book was released on 2000-04-17 with total page 854 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive account of the structures and physical chemistry properties of nucleic acids, with special emphasis on biological function, this text has been organized to meet the needs of those who have only a basic understanding of physical chemistry and molecular biology.
Download or read book The Biochemistry of the Nucleic Acids written by James Norman Davidson and published by . This book was released on 1972 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biochemistry of the Nucleic Acids.
Download or read book Principles of Nucleic Acid Structure written by Wolfram Saenger and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the grad uate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. CHARLES R. CANTOR New York Preface This monograph is based on a review on polynucleotide structures written for a book series in 1976.
Download or read book Nucleic acids and nucleotides written by U Satyanarayana and published by Elsevier Health Sciences. This book was released on 2014-11-07 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nucleic acids and nucleotides Nucleic acids and nucleotides
Download or read book The Biochemistry of the Nucleic Acids written by Roger Lionel Poulter Adams and published by Chapman & Hall. This book was released on 1981 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nucleic Acids Chemistry written by Ramon Eritja and published by Walter de Gruyter GmbH & Co KG. This book was released on 2021-01-18 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book compiles recent research on the modification of nucleic acids. It covers backbone modifications and conjugation of lipids, peptides and proteins to oligonucleotides and their therapeutic use. Synthesis and application in biomedicine and nanotechnology of aptamers, fluorescent and xeno nucleic acids, DNA repair and artificial DNA are discussed as well.
Download or read book Handbook of Biochemistry written by Gerald D Fasman and published by CRC Press. This book was released on 2019-08-08 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains information on the nucleotide composition of bacterial DNA. Eukaryotic protists, etc.; Nearest neighbour frequencies in DNA; repeated and unique sequences in eukaryotes; nucleic acid sequences in bacteriophage, chloroplasts, mitochondria, kinetoplasts, satellites and TRNA. Information on the physical properties of RNA, atomic coordinates of DNA-DNA. Also included in this volume is information on enzymes involved in nucleic acid function.
Download or read book The Biochemistry of the Nucleic Acids written by R. L Adams and published by . This book was released on 1986-10-16 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Biochemistry written by Gerald D Fasman and published by CRC Press. This book was released on 2019-08-08 with total page 1106 pages. Available in PDF, EPUB and Kindle. Book excerpt: The section of this handbook has been dividing into two volumes, the first volume contains information relating to purines, pyrimidine and nucleoside, oligonucleotide, polynucleotides, and their derivatives. Both ribo and deoxyribo compounds are listed also. The second volume will contain the remaining material similar to Volume 1 and material more relative to genetic and biological aspects such as enzymes involved in nucleic acid function, protein synthesis, linkage maps.
Download or read book Proteins and Nucleic Acids written by Abraham Marcus and published by Elsevier. This book was released on 2014-05-10 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biochemistry of Plants: A Comprehensive Treatise, Volume 6: Proteins and Nucleic Acids provides information pertinent to the nucleic acids and the regulation of the expression of this information. This book presents the processes by which the nucleic acids are finally expressed as proteins. Organized into 14 chapters, this volume begins with an overview of the overall structure of eukaryotic genomes, with emphasis on higher-plant DNA. This text then examines the enzymes involved in the cleavage and degradation of DNA. Other chapters provide a critical assessment of eukaryotic nucleic acid polymerases. This book discusses as well some examples from plant mitochondrial systems. The final chapter deals with two special areas of plant biology where the expression of the nucleic acids is seen in striking relief, the formation of plant tumors, and the growth and expression of plant viruses. This book is a valuable resource for plant biochemists, molecular biologists, senior graduate students, and research workers.
