Download or read book The Application of Texture Analysis for the Study of Liver Disease by Magnetic Resonance Imaging written by Akbar Gharbali and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Texture Analysis for Magnetic Resonance Imaging written by Milan Hájek and published by Texture Analysis Magn Resona. This book was released on 2006 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Non Invasive Characterization of Liver Disease written by Markus Karlsson and published by Linköping University Electronic Press. This book was released on 2019-12-13 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is a large and unmet need for diagnostic tool that can be used to characterize chronic liver diseases (CLD). In the earlier stages of CLD, much of the diagnostics involves performing biopsies, which are evaluated by a histopathologist for the presence of e.g. fat, iron, inflammation, and fibrosis. Performing biopsies, however, have two downsides: i) biopsies are invasive and carries a small but non-negligible risk for serious complications, ii) biopsies only represents a tiny portion of the liver and are thus prone to sampling error. Moreover, in the later stages of CLD, when the disease has progressed far enough, the ability of the liver to perform its basic function will be compromised. In this stage, there is a need for better methods for accurately measuring liver function. Additionally, measures of liver function can also be used when developing new drugs, as biomarkers for drug-induced liver injury (DILI), which is a serious drug-safety issue. Magnetic resonance imaging (MRI) is a non-invasive medical imaging modality, which have shown much promise with regards to characterizing liver disease in all of the abovementioned aspects. The aim of this PhD project was to develop and validate MR-based methods that can be used to non-invasively characterize liver disease. Paper I investigated if R2* mapping, a MR-method for measuring liver iron content, can be confounded by liver fat. The results show fat does affect R2*. The conclusion was therefore that fat must be taken into account when measuring small amounts of liver iron, as a small increase in R2* could be due to either small amounts of iron or large amounts of fat. Paper II examined whether T1 mapping, which is another MR-method, can be used for staging liver fibrosis. The results of previous research have been mixed; some studies have been very promising, whereas other studies have been less promising. Unfortunately, the results in Paper II belongs to the less promising studies. Paper III focused on measuring liver function by dynamic contrast-enhanced MRI (DCEMRI) using a liver specific contrast agent, which is taken up the hepatocytes and excreted to the bile. The purpose of the paper was to extend and validate a method for estimating uptake and efflux rates of the contrast agent. The method had previously only been applied in health volunteers. Paper II showed that the method can be applied to CLD patients and that the uptake of the contrast agent is lower in patients with advanced fibrosis. Paper IV also used studied liver function with DCE-MRI in patients with primary sclerosing cholangitis (PSC). PSC is a CLD where the bile ducts are attacked by the immune system. When diagnosing PSC patients, it is common to use magnetic resonance cholangiopancreatography (MRCP), which is a method for imaging the bile ducts. Paper IV examined if there was any correlation between number and severity of the morphological changes, seen on MRCP, and measures of liver function derived using DCE-MRI. However, the results showed no such correlation. The conclusion was that the results indicates that MRCP should not be used to predict parenchymal function. Paper V developed a method for translating DCE-MRI liver function parameters from rats to humans. This translation could be of value when developing new drugs, as a tool for predicting which drugs might cause drug-induced liver injury. In summary, this thesis has shown that multimodal quantitative MR has a bright future for characterizing liver disease from a range of different aspects.

Download or read book MRI of the Liver written by Günther Schneider and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent technological developments have broadened considerably the role of magnetic resonance imaging in the evaluation of liver pathology. Today, MR imaging is not looked upon merely as a problem-solving technique but is widely considered the principal imaging modality for both the detection and accurate diagnosis of focal and diffuse liver disease. Advances in hardware and sequence design and the advent of novel contrast agents with liver-specific properties have contributed towards making MRI of the liver a routine clinical application. Compared with previous publications on the application of MRI to study the liver, this book stands out in at least three major respects: - It presents in a clear and concise manner the current approaches to routine MRI of the liver, taking account of the hardware and software currently available from the major manufacturers and proposing imaging protocols for each. - A vast number of illustrations describe the pathologic and radiological correlations of the principal focal and diffuse liver diseases. - It presents a practical rationale for the use of contrast agents with liver-specific properties. This book will prove invaluable to radiologists wishing to expand or consolidate their routine approach to MR imaging of the liver.

Download or read book Contrast enhanced Magnetic Resonance Image Registration Segmentation and Feature Analysis for Liver Disease Diagnosis written by Ji Hun Oh and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The global objectives of this research are to develop a liver-specific magnetic resonance (MR) image registration and segmentation algorithms and to find highly correlated MR imaging features that help automatically score the severity of chronic liver disease (CLD). For a concise analysis of liver disease, time sequences of 3-D MR images should be preprocessed through an image registration to compensate for the patient motion, respiration, or tissue motion. To register contrast-enhanced MR image volume sequences, we propose a novel version of the demons algorithm that is based on a bi-directional local correlation coefficient (Bi-LCC) scheme. This scheme improves the speed at which a convergent sequence approaches to the optimum state and achieves the higher accuracy. Furthermore, the simple and parallelizable hierarchy of the Bi-LCC demons can be implemented on a graphics processing unit (GPU) using OpenCL. To automate segmentation of the liver parenchyma regions, an edge function-scaled region-based active contour (ESRAC), which hybridizes gradient and regional statistical information, with approximate partitions of the liver was proposed. Next, a significant purpose in grading liver disease is to assess the level of remaining liver function and to estimate regional liver function. On motion-corrected and segmented liver parenchyma regions, for quantitative analysis of the hepatic extraction of liver-specific MRI contrast agent, liver signal intensity change is evaluated from hepatobiliary phases (3-20 minutes), and parenchymal texture features are deduced from the equilibrium (3 minutes) phase. To build a classifier using texture features, a set of training input and output values, which is estimated by experts as a score of malignancy, trains the supervised learning algorithm using a multivariate normal distribution model and a maximum a posterior (MAP) decision rule. We validate the classifier by assessing the prediction accuracy with a set of testing data.

Download or read book The Application of Texture Analysis Pipeline on MRE Imaging for HCC Diagnosis written by Gaurav Bansal and published by . This book was released on 2013 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hepatocellular carcinoma (HCC) is a malignant tumor and is the seventh most common cancer in human. Every year there is a significant rise in the number of patients suffering from HCC. Most clinical research has focused on HCC early detection so that there are high chances of patient's survival. Emerging advancements in functional and structural imaging techniques have provided the ability to detect microscopic changes in tumor micro environment and micro structure. The prime focus of this thesis is to validate the applicability of advanced imaging modality, Magnetic Resonance Elastography (MRE), for HCC diagnosis. The research was carried out on three HCC patient's data and three sets of experiments were conducted. The main focus was on quantitative aspect of MRE in conjunction with Texture Analysis, an advanced imaging processing pipeline and multi-variate analysis machine learning method for accurate HCC diagnosis. We analyzed the techniques to handle unbalanced data and evaluate the efficacy of sampling techniques. Along with this we studied different machine learning algorithms and developed models using them. Performance metrics such as Prediction Accuracy, Sensitivity and Specificity have been used for evaluation for the final developed model. We were able to identify the significant features in the dataset and also the selected classifier was robust in predicting the response class variable with high accuracy.

Download or read book Diseases of the Abdomen and Pelvis 2018 2021 written by Juerg Hodler and published by Springer. This book was released on 2018-03-20 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.

Download or read book 3rd Kuala Lumpur International Conference on Biomedical Engineering 2006 written by F. Ibrahim and published by Springer Science & Business Media. This book was released on 2007-04-28 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Kuala Lumpur International Conference on Biomedical Engineering (BioMed 2006) was held in December 2006 at the Palace of the Golden Horses, Kuala Lumpur, Malaysia. The papers presented at BioMed 2006, and published here, cover such topics as Artificial Intelligence, Biological effects of non-ionising electromagnetic fields, Biomaterials, Biomechanics, Biomedical Sensors, Biomedical Signal Analysis, Biotechnology, Clinical Engineering, Human performance engineering, Imaging, Medical Informatics, Medical Instruments and Devices, and many more.

Download or read book Incorporation of texture analysis in diagnosing and characterizing cancer written by Chuanming Li and published by Frontiers Media SA. This book was released on 2023-06-29 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Handbook of Texture Analysis written by Ayman El-Baz and published by CRC Press. This book was released on 2024-06-24 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: The major goals of texture research in computer vision are to understand, model, and process texture, and ultimately, to simulate the human visual learning process using computer technologies. In the last decade, artificial intelligence has been revolutionized by machine learning and big data approaches, outperforming human prediction on a wide range of problems. In particular, deep learning convolutional neural networks (CNNs) are particularly well suited to texture analysis. This book examines four major application domains related to texture analysis and their relationship to AI-based industrial applications: texture classification, texture segmentation, shape from texture, and texture synthesis. This volume: Discusses texture-based segmentation for extracting image shape features, modeling and segmentation of noisy and textured images, spatially constrained color-texture model for image segmentation, and texture segmentation using Gabor filters Examines textural features for image classification, a statistical approach for classification, texture classification from random features, and applications of texture classifications Describes shape from texture, including general principles, 3D shapes, and equations for recovering shape from texture Surveys texture modeling, including extraction based on Hough transformation and cycle detection, image quilting, gray level run lengths, and use of Markov random fields Aimed at researchers, academics, and advanced students in biomedical engineering, image analysis, cognitive science, and computer science and engineering, this is an essential reference for those looking to advance their understanding in this applied and emergent field.

Download or read book World Congress on Medical Physics and Biomedical Engineering September 7 12 2009 Munich Germany written by Olaf Dössel and published by Springer Science & Business Media. This book was released on 2010-01-01 with total page 1211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Present Your Research to the World! The World Congress 2009 on Medical Physics and Biomedical Engineering – the triennial scientific meeting of the IUPESM - is the world’s leading forum for presenting the results of current scientific work in health-related physics and technologies to an international audience. With more than 2,800 presentations it will be the biggest conference in the fields of Medical Physics and Biomedical Engineering in 2009! Medical physics, biomedical engineering and bioengineering have been driving forces of innovation and progress in medicine and healthcare over the past two decades. As new key technologies arise with significant potential to open new options in diagnostics and therapeutics, it is a multidisciplinary task to evaluate their benefit for medicine and healthcare with respect to the quality of performance and therapeutic output. Covering key aspects such as information and communication technologies, micro- and nanosystems, optics and biotechnology, the congress will serve as an inter- and multidisciplinary platform that brings together people from basic research, R&D, industry and medical application to discuss these issues. As a major event for science, medicine and technology the congress provides a comprehensive overview and in–depth, first-hand information on new developments, advanced technologies and current and future applications. With this Final Program we would like to give you an overview of the dimension of the congress and invite you to join us in Munich! Olaf Dössel Congress President Wolfgang C.

Download or read book Hepatocellular Carcinoma written by Yujin Hoshida and published by Springer. This book was released on 2019-08-05 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields. By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.

Download or read book 5th European Conference of the International Federation for Medical and Biological Engineering 14 18 September 2011 Budapest Hungary written by Ákos Jobbágy and published by Springer Science & Business Media. This book was released on 2012-02-02 with total page 1477 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the 5th European Conference of the International Federation for Medical and Biological Engineering (EMBEC), held in Budapest, 14-18 September, 2011. The scientific discussion on the conference and in this conference proceedings include the following issues: - Signal & Image Processing - ICT - Clinical Engineering and Applications - Biomechanics and Fluid Biomechanics - Biomaterials and Tissue Repair - Innovations and Nanotechnology - Modeling and Simulation - Education and Professional

Download or read book Computed Tomography Magnetic Resonance Imaging Of The Whole Body E Book written by John R. Haaga and published by Elsevier Health Sciences. This book was released on 2016-06-06 with total page 2836 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now more streamlined and focused than ever before, the 6th edition of CT and MRI of the Whole Body is a definitive reference that provides you with an enhanced understanding of advances in CT and MR imaging, delivered by a new team of international associate editors. Perfect for radiologists who need a comprehensive reference while working on difficult cases, it presents a complete yet concise overview of imaging applications, findings, and interpretation in every anatomic area. The new edition of this classic reference — released in its 40th year in print — is a must-have resource, now brought fully up to date for today's radiology practice. - Includes both MR and CT imaging applications, allowing you to view correlated images for all areas of the body. - Coverage of interventional procedures helps you apply image-guided techniques. - Includes clinical manifestations of each disease with cancer staging integrated throughout. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices. - Over 5,200 high quality CT, MR, and hybrid technology images in one definitive reference. - For the radiologist who needs information on the latest cutting-edge techniques in rapidly changing imaging technologies, such as CT, MRI, and PET/CT, and for the resident who needs a comprehensive resource that gives a broad overview of CT and MRI capabilities. - Brand-new team of new international associate editors provides a unique global perspective on the use of CT and MRI across the world. - Completely revised in a new, more succinct presentation without redundancies for faster access to critical content. - Vastly expanded section on new MRI and CT technology keeps you current with continuously evolving innovations.

Download or read book Magnetic Resonance Elastography written by Sudhakar K. Venkatesh and published by Springer. This book was released on 2014-10-01 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book to cover the groundbreaking development and clinical applications of Magnetic Resonance Elastography, this book is essential for all practitioners interested in this revolutionary diagnostic modality. The book is divided into three sections. The first covers the history of MRE. The second covers technique and clinical applications of MRE in the liver with respect to fibrosis, liver masses, and other diseases. Case descriptions are presented to give the reader a hands-on approach. The final section presents the techniques, sequence and preliminary results of applications in other areas of the body including muscle, brain, lung, heart, and breast.

Download or read book Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by and published by . This book was released on 2008 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Quantitative Magnetic Resonance Imaging written by Nicole Seiberlich and published by Academic Press. This book was released on 2020-11-18 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Magnetic Resonance Imaging is a 'go-to' reference for methods and applications of quantitative magnetic resonance imaging, with specific sections on Relaxometry, Perfusion, and Diffusion. Each section will start with an explanation of the basic techniques for mapping the tissue property in question, including a description of the challenges that arise when using these basic approaches. For properties which can be measured in multiple ways, each of these basic methods will be described in separate chapters. Following the basics, a chapter in each section presents more advanced and recently proposed techniques for quantitative tissue property mapping, with a concluding chapter on clinical applications. The reader will learn: - The basic physics behind tissue property mapping - How to implement basic pulse sequences for the quantitative measurement of tissue properties - The strengths and limitations to the basic and more rapid methods for mapping the magnetic relaxation properties T1, T2, and T2* - The pros and cons for different approaches to mapping perfusion - The methods of Diffusion-weighted imaging and how this approach can be used to generate diffusion tensor - maps and more complex representations of diffusion - How flow, magneto-electric tissue property, fat fraction, exchange, elastography, and temperature mapping are performed - How fast imaging approaches including parallel imaging, compressed sensing, and Magnetic Resonance - Fingerprinting can be used to accelerate or improve tissue property mapping schemes - How tissue property mapping is used clinically in different organs - Structured to cater for MRI researchers and graduate students with a wide variety of backgrounds - Explains basic methods for quantitatively measuring tissue properties with MRI - including T1, T2, perfusion, diffusion, fat and iron fraction, elastography, flow, susceptibility - enabling the implementation of pulse sequences to perform measurements - Shows the limitations of the techniques and explains the challenges to the clinical adoption of these traditional methods, presenting the latest research in rapid quantitative imaging which has the possibility to tackle these challenges - Each section contains a chapter explaining the basics of novel ideas for quantitative mapping, such as compressed sensing and Magnetic Resonance Fingerprinting-based approaches