Download or read book The Antibody Enigma written by Thomas Kindt and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Antibody Enigma is a somewhat personal view of the antibody diversity question from two investigators who have spent the past 18 years trying to penetrate the enigma. It is not and was not meant to be an all-embracing comprehensively referenced review of the subject of antibody diversity. Because of the subjective viewpoint, there are un doubtedly omissions of data that others consider to be seminal, and if we have offended anyone by omitting their own contribution we sin cerelyapologize. We have lived with "The Enigma" on and off for the past two years. It has been both hard work and good fun but, above all, it has been a learning experience. There were several difficult decisions to make in putting together the final text, but perhaps the most difficult was de ciding upon a stopping point. The field of antibody diversity is presently enjoying an unparalleled expansion of information, and because of this it was very tempting to await further developments in hopes of tying up as many loose ends as possible. This was decided against for several reasons; the major factor was that the project was growing burdensome for both of us. From a more objective point of view this appears to be a reasonable time to stop our exposition.
Download or read book Infection Resistance and Immunity Second Edition written by Julius Kreier and published by Taylor & Francis. This book was released on 2022-04-18 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as an introductory textbook, Infection, Resistance and Immunity provides basic information on the workings of the immunological system and on infectious processes and their control. With sections on immunological disorders, immunization, immunodiagnosis, and epidemiology, it relates immunology to practical problems in medicine. The book includes a section on comparative immunology, introducing students to differences among immunological systems among common species of nonhuman animals. Written for the advanced undergraduate, the focus is on host-parasite interactions—distinguishing this text from other standard texts, which focus on the cellular mechanisms of the immune response.
Download or read book A History of Immunology written by Arthur M. Silverstein and published by Elsevier. This book was released on 2012-12-02 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a professional-level intellectual history of the development of immunology from about 1720 to about 1970. Beginning with the work and insights of the early immunologists in the 18th century, Silverstein traces the development of the major ideas which have formed immunology down to the maturation of the discipline in the decade following the Second World War. Emphasis is placed on the philosophic and sociologic climate of the scientific milieu in which immunology has developed, providing a background to the broad culture of the discipline. A professional-level intellectual history of the development of immunology from about 1720 to 1970, with emphasis placed on the social climate of the scientific milieu in which modern immunology evolved Written by an author very well known both as a historian of medical science and for his substantial research contributions to the immunopathology of the eye The only complete history of immunology available
Download or read book The Antibody Molecule written by Anthony R. Rees and published by Oxford Medical Histories. This book was released on 2015 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'The Antibody Molecule' is a beautifully illustrated review of the remarkable developments within immunology from the discovery of the antibody molecule to its exploitation in medicine and the scientists and pioneers who were involved. This engaging and authoritative history will appeal to a wide audience
Download or read book Investigation and Exploitation of Antibody Combining Sites written by Eric Reid and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Kuby Immunology written by Thomas J. Kindt and published by Macmillan. This book was released on 2007 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally authored by the award winning author Janis Kuby, "Immunology" remains the best selling textbook for the undergraduate course. The first and only true textbook written by professors who teach the undergraduate course, it presents the most current concepts in an experimental context with clinical advances highlighted in boxes, supported by the kind of helpful pedagogical tools that other books do not provide.
Download or read book Antibodies in Cell Biology written by and published by Academic Press. This book was released on 1993-11-17 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibodies in Cell Biology focuses on a new generation of protocols aimed at the cell biologist. This laboratory manual features systems and techniques that are especially relevant for modern problems. The contributing authors have been carefully chosen for their specific expertise, and have provided detailed protocols, recipes, and troubleshooting guides in each chapter. The book is designed for any researcher or student who needs to use antibodies in cell biology and related research areas. Practical applications and future emphases of antibodies, including: Light microscopic immunolocalization of antigens Gold particles in immunoelectron microscopy Special methods of fixation and permeabilization Microinjection of antibodies into living cells Antibodies to identify cDNA clones Antisense antibody strategies
Download or read book Advances in Immunology written by and published by Academic Press. This book was released on 1994-07-06 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Leader in Immunology
Download or read book Progress in Immunology Vol VIII written by M. Benczur and published by Springer. This book was released on 2013-12-21 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: At this congress there were again numereous reports of progress in immunology. The new technologies are continuing to have an immense impact: gene isolation, mutation, transfection and expression, protein structure andpeptide synthesis, cell cloning, hybridization and monoclonal antibodies, CD serology, SCID and transgenic mice, modern immunomodulation and vaccines. A trmendous mass of data has accumulated over the last years. The reports are up-to-date and outstanding,to a degree no journal will ever achieve, and the results are presented in a concise and lucid way. This report will serve as a guideline for the years to came, because it is a treasure trove of explorations, making it exciting reading. This progress presents outstanding contributions. Immunology is exhibited at its best: an exciting research area and a rewarding subject to study for the benefit of mankind - today more than ever.
Download or read book Monoclonal Antibodies written by James W. Goding and published by Elsevier. This book was released on 1996-02-26 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monoclonal Antibodies now have applications in virtually all areas of biology and medicine, and much of the world's biotechnology industry has its foundations in the exploitation of this technology. The Third Edition of this well established book meets the needs of both newcomers to the area and experienced researchers, by providing an integrated treatment of both the production and application of monoclonal antibodies. As in previous editions, detailed and critical accounts of the theory, production, purification, fragmentation, storage and radiolabelling of monoclonal antibodies are given, along with descriptions of their use in antigen characterization, affinity chromatography and immunofluorescence. The present volume has been comprehensively updated to cover recent rapid advances, particularly with respect to the applications of molecular biology, the use of antibodies in closing and heterologous expression of genes, immunohistology and phage display libraries. Since the previous edition, there has been a growing trend towards the replacement of procedures using radioactive isotopes, and the current edition incorporates these newer technologies. The text is oriented towards problems solving, and makes it easy to adapt each procedure to individual needs. Extensive cross-referencing, a glossary and a comprehensive index make this book an essential reference. This book will be vital both for laboratories already producing or using monoclonal antibodies, and for workers in many disciplines who are contemplating their use. Provides an integrated treatment of both the production and application of monoclonals in cell biology, biochemistry, and immunology Gives detailed and critical accounts of the theory, production, purification, storage, and relabelling of monoclonals, and their use in antigen characterization, affinity chromorography, and immunofluroscence Comprehensively updated to cover the rapid advances that have occurred since the publication of the Second Edition
Download or read book Immunology written by Klaus D. Elgert and published by John Wiley & Sons. This book was released on 2009-09-08 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blends biology, clinical science, genetics, and molecular biology of the immune system to provide a complete account of our knowledge of immunology New features include full-color artwork and design, over 50 new figures, and text that has been completely revised to reflect the very latest references Incorporates a variety of pedagogical aids to assist students in the learning process, including chapter outlines, objectives, and summaries, as well as a self-evaluation section
Download or read book Antibodies and Their Role in Therapeutics written by Roohi Bansal and published by Roohi Bansal. This book was released on 2021-12-04 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Beginning with the structure, types, functions, and gene organization of antibodies, the book aims to shine a detailed light on the monoclonal antibodies (often referred to as mAbs) that have revolutionized the fields of therapeutics and diagnostics. The book describes the different ways of generating chimeric, humanized, and fully human monoclonal antibodies, emphasizing phage display, hybridoma, and rDNA technology. In addition, the book focuses on the various recombinant antibody formats in detail: Drug conjugates: Antibody-drug conjugates (ADCs), Immunotoxins (Recombinant, Humanized and Fully Human) and Antibody-antibiotic conjugate (AAC) Bispecific antibodies: scFv based (BiTE, DARTs and TandAbs) and Full-length IgG based Abzymes and Antibody-directed enzyme prodrug therapy (ADEPT) Fc-fusion proteins Single-domain antibodies (VHH and IgNAR sdAb) The book discusses the various therapeutic applications of monoclonal antibodies, along with the immunogenicity issues. The book also covers the modes of administration and side effects of monoclonal antibodies, along with the challenges and issues faced while developing a monoclonal antibody into a therapeutic agent. Modifications introduced by the researchers to decrease the immunogenicity issues and increase the efficacy of therapeutic mAbs are also described. The book is an invaluable resource for researchers and students in biology and medicine, biotechnology, immunology, genetics, molecular biology, and anyone interested in antibody engineering.
Download or read book Immunoglobulins in Health and Disease written by M. French and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid advances continue to be made in all areas of immunology, not least the biology of the immunoglobulins. This knowledge has resulted in a better understanding of antibody responses and helped to clarify pathogenic mechanisms in many diseases, particularly autoimmune and allergic diseases, as well as expand our comprehension of antibody deficiency diseases and mechanisms in therapeutic immunization. In addition, the recognition that diverse disease states may result in abnormalities of the amount of immunoglobulins in body fluids has resulted in the use of immunoglobulin assays for disease diagnosis and management. The aim of this book has been to condense both the established and recent aspects of this knowledge, particularly that pertaining to clinical immunology. The contributions of different authors hopefully provide a comprehensive review of their particular field of interest as well as a discussion of how this information can be applied to clinical medicine. Immunological terms and concepts have been explained where appropriate so that the book can be read by those with only a basic knowledge of immunology. In producing a book on this one area of immunology some duplication of information has been accepted so that topics can be considered in different contexts. I hope the book will be of value to those in training or already pursuing a career in clinical or laboratory medicine by providing a basic and short text on immunoglobulins. M.A.H.F.
Download or read book Molecular Biology and Immunology of Allergens written by Dietrich Kraft and published by CRC Press. This book was released on 1993-03-25 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology and Immunology of Allergens explores the characteristics of natural allergens and allergens produced by recombinant DNA techniques. The book covers important inhalant allergens such as pollen, mites, molds, and pet dander, as well as insect venoms and Chironomid hemoglobin allergens. Biological functions of allergens; the structural definition of allergens by NMR, crystallography, and computer modeling; and the production of recombinant allergens are discussed. Special attention is given to the search for the most effective expression systems in prokaryotic and eukaryotic organisms and the purification of recombinant allergens as fusion and non-fusion proteins. Other topics addressed include the production of allergen-specific T cell clones, the discovery of T cell epitopes by stimulation with overlapping peptides, and methods to induce T cell anergy by tolerogenic allergen-derived peptides. Molecular Biology and Immunology of Allergens will be an excellent reference for all researchers and clinicians in allergology, immunology, molecular biology, allergen extracting, and immunotherapy.
Download or read book Further Milestones in Biochemistry written by M.G. Ord and published by Elsevier. This book was released on 1997-05-16 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contributors to this text, who are all biochemists who worked during the 1950s and 60s, describe what appears to them to be the conceptually significant developments in biochemistry since the mid 1950s and how these were achieved. Their aim is to make their subjects intelligible to other scientists not expert in their field.
Download or read book Immunoglobulin Genes written by Tasuku Honjo and published by Academic Press. This book was released on 2012-12-02 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunoglobin Genes is the first comprehensive book on the structure, function, and expression of the genes encoding antibodies in normal and neoplastic cells.
Download or read book Paul Ehrlich s Receptor Immunology written by Arthur M. Silverstein and published by Elsevier. This book was released on 2001-11-17 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Paul Ehrlich's Receptor Immunology: The Magnificent Obsession describes the background to Paul Ehrlich's immunological works and theories and delves into the substance of his experiments in great detail. By exploring these early developments in immunology, the book lays the foundation for modern concepts, providing immunologists, biomedical researchers, and students the context for the discoveries in their field. The selectionist theory of antibody formation Kinetics of primary and secondary antibody response Quantitative methods of measurement of antigens and antibody Demonstration of passive transfer of immunity from mother to foetus
