Download or read book TGF in Human Disease Friend or Foe written by Guoping Zheng and published by Frontiers Media SA. This book was released on 2021-11-26 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Signaling Pathways and Molecular Mediators in Metastasis written by Alessandro Fatatis and published by Springer Science & Business Media. This book was released on 2012-01-03 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents the most advanced discoveries from translational research laboratories directly involved in identifying molecules and signalling pathways that play an instrumental role in metastasis. In contrast to other works, conventionally focused on a single type of tumour, the various chapters in this book provide a broad perspective of the similarities and discrepancies among the dissemination of several solid malignancies. Through recurrent and overlapping references to molecular mechanisms and mediators, the readers will gain knowledge of the common ground in metastasis from a single source. Finally, an introductory chapter provides a clinical perspective of the problems presented by metastatic tumours for diagnosis and treatment. The work presented here is directed to researchers in tumour biology with a developing interest in metastatic dissemination as well as medical and graduate students seeking to expand and integrate the notions acquired in basic cancer biology and oncology courses.
Download or read book Cancer Cell Signaling written by Kasirajan Ayyanathan and published by CRC Press. This book was released on 2014-06-20 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title includes a number of Open Access chapters.Cell signaling is a field that studies how cells communicate to control basic activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a cellular level, an understanding that may have implications for developi
Download or read book Fetal and Neonatal Physiology written by Richard Polin and published by Elsevier Health Sciences. This book was released on 2021-07-29 with total page 2555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering the comprehensive, authoritative information needed for effective diagnosis, treatment, and management of sick and premature infants, Fetal and Neonatal Physiology, 6th Edition, is an invaluable resource for board review, clinical rounds, scientific research, and day-to-day practice. This trusted two-volume text synthesizes recent advances in the field into definitive guidance for today’s busy practitioner, focusing on the basic science needed for exam preparation and key information required for full-time practice. It stands alone as the most complete text available in this complex and fast-changing field, yet is easy to use for everyday application. Offers definitive guidance on how to effectively manage the many health problems seen in newborn and premature infants. Contains new chapters on Pathophysiology of Genetic Neonatal Disease, Genetic Variants and Neonatal Disease, and Developmental Biology of Lung Stem Cells, as well as significantly revised chapters on Cellular Mechanisms of Neonatal Brain Injury, Neuroprotective Therapeutic Hypothermia, Enteric Nervous System Development and Gastrointestinal Motility, and Physiology of Twin-Twin Transfusion. Features 1,000 full-color diagrams, graphs and anatomic illustrations, 170+ chapters, and more than 350 global contributors. Includes chapters devoted to clinical correlation that help explain the implications of fetal and neonatal physiology, as well as clinical applications boxes throughout. Provides summary boxes at the end of each chapter and extensive cross-referencing between chapters for quick reference and review. Allows you to apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more.
Download or read book Create the World Without Disease written by Mohammad Munir Hossain Khan MBBS PhD and published by AuthorHouse. This book was released on 2022-05-04 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written about a miracle method by which we may hope to have a “World without disease”: IT IS BASED ON THE COMBINATION OF SOME SIMPLE BASIC SCIENTIFIC FACTS • PROTEASES (enzymes), IN ADDITION TO HAVE BENEFICIAL FUNCTIONS IN OUR BODY, CAN ALSO INVOLVED IN THE TRIGGERING OF MANY DISEASES. • POLYPHENOL (PP) CONTAINING FOODS INCREASE A PROTEIN CALLED ALPHA-2-MACROGLOBULIN - A2M (A BROAD SPECTRUM PROTEASE INHIBITOR) NATURALLY FROM LIVER IN OUR BODY AND PROTECT US FROM THE TOXIC EFFECTS OF PROTEASES. • IN A CLINICAL STUDY WE HAVE SHOWN THAT WHEN THE CONCENTRATION OF A2M IS LOW IN OUR BODY FOR ANY REASON, WE BECOME SICK • KEEPING A2M IN NORMAL CONCENTRATION IN OUR BODY IS ESSENTIAL TO KEEP US HEALTHY We need to know the reasons people die to improve how people live. Globally first 5 causes of death are as follows: In upper income countries 1. Ischemic heart disease 2. Alzheimer’s disease and dementias 3. Stroke 4. Trachea, Bronchus, lung cancer 5. Chronic obstructive pulmonary disease In upper and lower middle income countries 1. Ischemic heart disease 2. Stroke 3. Chronic obstructive pulmonary disease 4. Trachea, Bronchus, lung cancer 5. Lower respiratory infection In contrast In lower income countries 1. Neonatal conditions 2. Lower respiratory infection 3. Ischemic heart disease 4. Stroke 5. Diarrheal disease • I INVENTED A LIST OF SOME SIMPLE, INEXPENSIVE AND EASILY AVAILABLE FOOD ITEMS WITH SOME SUPERFOODS WHICH CAN STIMULATE THE LIVER TO RELEASE NATURAL UNACTIVATED A2M. • USING THESE FOODS, 465 PEOPLE ARE ENJOYING THEIR HEALTHY LIFE (NOT EVEN FEVER, COUGH OR ANY OTHER HEALTH ISSUES) FOR LAST 4 TO 5 YEARS. • SO FAR (01-12-2022), NONE OF THE VOLANTEERS, USING THESE FOODS HAD SUFFERED FROM CURRENT PANDEMIC COVIT-19 I SUGGEST TO INCLUDE SERUM A2M TEST IN OUR REGULAR BLOOD WORK TO CHECK OUR HEALTH STATUS.
Download or read book Probiotics in The Prevention and Management of Human Diseases written by Mitesh Kumar Dwivedi and published by Academic Press. This book was released on 2021-12-02 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Probiotics in The Prevention and Management of Human Diseases: A Scientific Perspective addresses the use of probiotics and their mechanistic aspects in diverse human diseases. In particular, the mechanistic aspects of how these probiotics are involved in mitigating disease symptoms (novel approaches and immune-mechanisms induced by Probiotics), clinical trials of certain probiotics, and animal model studies will be presented through this book. In addition, the book covers the role of probiotics in prevention and management aspects of crucial human diseases, including multidrug resistant infections, hospital acquired infections, allergic conditions, autoimmune diseases, metabolic disorders, gastrointestinal diseases, neurological disorders, and cancers. Finally, the book addresses the use of probiotics as vaccine adjuvants and as a solution for nutritional health problems and describes the challenges of using probiotics in management of human disease conditions as well as their biosafety concerns. Intended for nutrition researchers, microbiologists, physiologists, and researchers in related disciplines as well as students studying these topics require a resource that addresses the specific role of probiotics in the prevention and management of human disease. Contains information on the use of probiotics in significant human diseases, including antibiotic resistant microbial infections Presents novel applications of probiotics, including their use in vaccine adjuvants and concept of pharmabiotics Includes case studies and human clinical trials for probiotics in diverse disease conditions and explores the role of probiotics in mitigation of the symptoms of disease
Download or read book Portal Hypertension VII written by Roberto de Franchis and published by Springer Nature. This book was released on 2022-10-18 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, the seventh in a series of proceedings volumes that began in 1995, reviews the latest developments in the diagnosis and management of cirrhosis and portal hypertension. It addresses a broad range of topics, including: risk stratification, HVPG, non-invasive surrogates for cACLD, CSPH, varices, progression and regression of cirrhosis, impact of etiological therapy on cirrhosis, impact of non-etiological novel therapies on cirrhosis, prevention of first/further decompensation, acute variceal hemorrhage, and Vascular Liver Disorders in Cirrhosis (VALDIG). The book is a compilation of lectures and important consensus statements from the Seventh Baveno International Consensus Workshop on Portal Hypertension, the latest in a series of workshops held every five years for hepatologists with an interest in the field. Portal Hypertension VII offers a valuable reference guide for clinical and research fellows in Gastroenterology and Hepatology and will inspire new research projects in the promising areas identified by the experts of the Baveno VII Faculty.
Download or read book Inflammatory Bowel Disease written by Imre Szabo and published by BoD – Books on Demand. This book was released on 2012-12-05 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an overview of invited contributions on recent data of inflammatory bowel diseases. The first part of the book covers topics related to the ethiopathogenesis of inflammatory bowel diseases including the environmental, genetic factors and immunological alternations. The next chapters deal with present day management of disease including radiological diagnosis and surgical treatment, which consider the advances of most up-to-date radiological methodology including MRI techniques and the role of surgical procedures in the therapy. The final part presents medical therapy and its future directions. These chapters discuss natural products exerting anti-inflammatory and anti-tumour effects, methods of colon targeting drug delivery systems including polysaccharides, peptides and nanoparticules; as well as the potential risks of nanotechnology based food materials.
Download or read book Innate Lymphoid Cells in Cancer Friends or Foes written by Nicolas Jacquelot and published by Frontiers Media SA. This book was released on 2022-01-10 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Frontiers in Anti Cancer Drug Discovery written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2014-05-12 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Frontiers in Anti-Cancer Drug Discovery is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery, including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The Ebook series is essential reading for all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.
Download or read book Reproductive Immunology written by Gil Mor and published by Academic Press. This book was released on 2021-02-12 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reproductive Immunology: Basic Concepts gives a holistic insight into the understanding of the complex interactions between the maternal immune system and the fetal/placental unit necessary for the success of pregnancy. This interaction is critical for the support of the human fetal semiallograft and the protection against infections. The book covers various topics such as B cells, macrophages, T cells, discussion on fetal signals and their impact on maternal reproductive cells such as endometrial cells, mast cells, and the role of fetal Hofbauer cells, the immune regulatory role of glucorticoids, and many other novel topics within the field of reproductive immunology. Edited and written by experts in the field, this book introduces the up-to-date knowledge of the role of the immune system during pregnancy and provides the necessary background to understand pregnancy complications associated with alterations in the functioning of the immune system. The book provides a complete discussion on the immunological aspects of pregnancy and serves as a great tool for research scientists, students, reproductive immunologists and OBGYNs. Shows the detailed evaluation of the knowledge related to each immune cell type in the pregnant and not pregnant uterus Evaluates each immune cell type and its function during specific reproductive events Provides the biological background for understanding the clinical aspects that will be discussed in subsequent volumes in the series
Download or read book Fetal and Neonatal Physiology E Book written by Richard A. Polin and published by Elsevier Health Sciences. This book was released on 2011-08-13 with total page 2202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease.
Download or read book Fetal and Neonatal Physiology written by Richard A. Polin and published by Elsevier Health Sciences. This book was released on 2011-01-01 with total page 2213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease. Access the complete contents and illustrations online at expertconsult.com - fully searchable! Get the latest developments and a full understanding of the distinct physiology of the fetus and newborn so you can treat and manage sick newborns and preemies.
Download or read book Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation written by Gerard Socie and published by Academic Press. This book was released on 2018-11-22 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation: Models in Discovery and Translation, Second Edition once again provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemia effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes, and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. The second edition is fully revised and includes new chapters on microbiome, metabolism, kinase targets, micro-RNA and mRNA regulatory mechanisms, signaling pathways in GVHD, innate lymphoid system development, recovery and function in GVHD, genetically engineered T-cell therapies, immune system engagers for GVHD and graft-versus-tumor, and hematopoietic cell transplant for tolerance induction in solid organ grafts. Brings together perspectives from leading laboratories and clinical research groups to highlight advances from bench to the bedside Guides readers through the caveats that must be considered when drawing conclusions from studies with animal models before correlating to clinical allogeneic hematopoietic stem cell transplantation (HSCT) scenarios Categorizes the published advances in various aspects of immune biology of allogeneic HSCT to illustrate opportunities for clinical applications
Download or read book Advances in Immunology written by Frederick W. Alt and published by Academic Press. This book was released on 2021-06-25 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Immunology, Volume 150, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Presents current developments and comprehensive reviews in immunology Provides the latest in a longstanding and respected serial on the subject matter Focuses on recent advances in the advancing area of the mechanisms involved in the evolution of HIV-1 Neutralizing Antibodies
Download or read book Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease written by Venkataramana K Sidhaye and published by Academic Press. This book was released on 2017-03-09 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease provides a one-stop resource capturing developments in lung epithelial biology related to basic physiology, pathophysiology, and links to human disease. The book provides access to knowledge of molecular and cellular aspects of lung homeostasis and repair, including the molecular basis of lung epithelial intercellular communication and lung epithelial channels and transporters. Also included is coverage of lung epithelial biology as it relates to fluid balance, basic ion/fluid molecular processes, and human disease. Useful to physician and clinical scientists, the contents of this book compile the important and most current findings about the role of epithelial cells in lung disease. Medical and graduate students, postdoctoral and clinical fellows, as well as clinicians interested in the mechanistic basis for lung disease will benefit from the books examination of principles of lung epithelium functions in physiological condition. Provides a single source of information on lung epithelial junctions and transporters Discusses of the role of the epithelium in lung homeostasis and disease Includes capsule summaries of main conclusions as well as highlights of future directions in the field Covers the mechanistic basis for lung disease for a range of audiences
Download or read book Cell Mechanoresponse at Cell Material Interface written by Qiang Wei and published by Frontiers Media SA. This book was released on 2022-02-01 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt:
