Download or read book Hearings written by United States. Congress Senate and published by . This book was released on 1935 with total page 2372 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Energy Research Abstracts written by and published by . This book was released on 1977 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Semiannual, with semiannual and annual indexes. References to all scientific and technical literature coming from DOE, its laboratories, energy centers, and contractors. Includes all works deriving from DOE, other related government-sponsored information, and foreign nonnuclear information. Arranged under 39 categories, e.g., Biomedical sciences, basic studies; Biomedical sciences, applied studies; Health and safety; and Fusion energy. Entry gives bibliographical information and abstract. Corporate, author, subject, report number indexes.

Download or read book Central Link Light Rail Transit Project Seattle Tukwila and Seatac written by and published by . This book was released on 1999 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Pathogenesis and Treatment of Leukemia written by Harinder Gill and published by Springer Nature. This book was released on 2023-09-27 with total page 665 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a comprehensive update on acute and chronic leukemia. In 54 chapters, authors introduce research progress and clinical trials of acute myeloid leukaemia (AML), acute promyelocytic leukaemia (APL), acute lymphoblastic leukaemia (ALL), myelodysplastic syndrome (MDS), myeloproliferative neoplasm (MPN) and chronic myeloid leukemia (CML). The last decade has seen the integration of genetic and clinical information to determine the prognosis and treatment strategies. This book provides practitioners, researchers and graduate students of Hematology and Hematopathology a comprehensive update on the pathobiology, genomics, classification, diagnosis, monitoring, prognostication and therapy of both acute and chronic leukemias.

Download or read book Fringe benefits e rimborsi spese written by Gianluca Dan - Massimo Gabelli and published by IPSOA. This book was released on 2010-11-05 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: La quarta edizione del libro “Fringe benefits e rimborsi spese”, rinnovata ed aggiornata con le previsioni della Legge Finanziaria per il 2010, L. 23 dicembre 2009, n. 191, in materia di tassazione agevolata dei premi di produttività, tiene conto di molte e importanti modifiche normative che sono diventate operative nel corso degli ultimi anni, per esempio l’eliminazione dei regimi agevolativi precedentemente previsti per le stock option o i limiti di deducibilità delle spese relative a prestazioni alberghiere e alle somministrazioni di alimenti e bevande. Il volume, pur conservando l’originaria agilità di consultazione, fornisce una trattazione completa ed esaustiva del quadro di riferimento per la qualificazione e quantificazione dei redditi di lavoro dipendente ed assimilati, ne analizza le varie fattispecie che si possono incontrare nella pratica professionale, con particolare attenzione alla disciplina delle trasferte, e le relative modalità di rimborso degli oneri sostenuti dai dipendenti, e a quella dei fringe benefits. L’ultimo capitolo è stato riservato all’esame della disciplina della deducibilità, sia ai fini delle imposte dirette (Irpef/Ires) sia ai fini IRAP, degli oneri connessi ai dipendenti e collaboratori, per aiutare nella determinazione degli importi deducibili specie quelli la cui deduzione è soggetta a limitazioni. Utile per chi deve affrontare la compilazione della dichiarazione dei redditi.

Download or read book Demographic Challenges for the 21st Century written by Johan Surkyn and published by ASP / VUBPRESS / UPA. This book was released on 2008 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inspired by the work of Ron Lesthaeghe, retired Belgian professor of demography and social science research methodology, this collection of contributions is also based on a conference entitled "Demographic Challenges for the 21st Century: A State of the Art in Demography." During Ron Lesthaeghe’s tenure, he established himself as a scholar, publishing highly influential work that changed the face of demography and founded the research group, Interface Demography. Most of his research was in the various subfields of demography: historical, social, and economic, and mainly covered populations of Europe and of sub-Saharan Africa. He also researched the fields of cultural change in Europe and of ethnic minority studies. This book offers a collection of tributes to his contribution to demography, presented by leading international demographers.

Download or read book By Water Beneath the Walls written by Benjamin H. Milligan and published by Random House. This book was released on 2024-07-16 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: A gripping history chronicling the fits and starts of American special operations and the ultimate rise of the Navy SEALs from unarmed frogmen to elite, go-anywhere commandos—as told by one of their own. “Deeply researched, well organized, and incredibly engaging . . . This is our legacy with all the warts, the challenges, and the heroics in one concise volume.”—Admiral William H. McRaven, #1 New York Times bestselling author and former commander, United States Special Operations Command How did the US Navy—the branch of the US military tasked with patrolling the oceans—ever manage to produce a unit of raiders trained to operate on land? And how, against all odds, did that unit become one of the world’s most elite commando forces, routinely striking thousands of miles from the water on the battlefields of Iraq, Afghanistan, Syria, even Central Africa? Behind the SEALs’ improbable rise lies the most remarkable underdog story in American military history—and in these pages, former Navy SEAL Benjamin H. Milligan captures it as never before. Told through the eyes of remarkable leaders and racing from one longshot, hair-curling raid to the next, By Water Beneath the Walls is the tale of the unit’s heroic naval predecessors, and the evolution of the SEALs themselves. But it’s also the story of the forging of American special operations as a whole—and how the SEALs emerged from the fires as America’s first permanent commando force when again and again some other unit seemed predestined to seize that role. Here Milligan thrillingly captures the outsize feats of the SEALs’ frogmen forefathers in World War II, the Korean War, and elsewhere, even as he plunges us into the second front of interservice rivalries and personal ambition that shaped the SEALs’ evolution. In equally vivid, masterful detail, he chronicles key early missions undertaken by units like the Marine Raiders, Army Rangers, and Green Berets, showing us how these fateful, bloody moments helped create the modern American commando—even as they opened up pivotal opportunities for the Navy. Finally, he takes us alongside as the SEALs at last seize the mantle of commando raiding, and discover the missions of capture/kill and counterterrorism that would define them for decades to come. Now required reading throughout the US special operations community, By Water Beneath the Walls is an essential history of the SEAL teams, a crackling account of desperate last stands and unforgettable characters accomplishing the impossible—and a riveting epic of the dawn of American special operations.

Download or read book The London Gazette written by and published by . This book was released on 1921 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1976 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Multiple Myeloma New Insights for the Healthcare Professional 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-07-22 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Myeloma: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Multiple Myeloma: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Multiple Myeloma: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune Mediated Inflammatory Diseases written by Honghui Zhou and published by John Wiley & Sons. This book was released on 2019-03-19 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thorough Overview Identifies and Addresses Critical Gaps in the Treatment of Several Chronic Diseases With increasing numbers of patients suffering from Immune-Mediated Inflammatory Diseases (IMIDs), and with the increasing reliance on biopharmaceuticals to treat them, it is imperative that researchers and medical practitioners have a thorough understanding of the absorption, distribution, metabolism and excretion (ADME) of therapeutic proteins as well as translational pharmacokinetic/pharmacodynamic (PK/PD) modeling for them. This comprehensive volume answers that need to be addressed. Featuring eighteen chapters from world-renowned experts and opinion leaders in pharmacology, translational medicine and immunology, editors Honghui Zhou and Diane Mould have curated a much-needed collection of research on the advanced applications of pharmacometrics and systems pharmacology to the development of biotherapeutics and individualized treatment strategies for the treatment of IMIDs. Authors discuss the pathophysiology of autoimmune diseases in addition to both theoretical and practical aspects of quantitative pharmacology for therapeutic proteins, current translational medicine research methodologies and novel thinking in treatment paradigm strategies for IMIDs. Other notable features include: • Contributions from well-known authors representing leading academic research centers, specialized contract research organizations and pharmaceutical industries whose pipelines include therapeutic proteins • Chapters on a wide range of topics (e.g., pathophysiology of autoimmune diseases, biomarkers in ulcerative colitis, model-based meta-analysis use in the development of therapeutic proteins) • Case studies of applying quantitative pharmacology approaches to guiding therapeutic protein drug development in IMIDs such as psoriasis, inflammatory bowel disease, multiple sclerosis and lupus Zhou and Mould’s timely contribution to the critical study of biopharmaceuticals is a valuable resource for any academic and industry researcher working in pharmacokinetics, pharmacology, biochemistry, or biotechnology as well as the many clinicians seeking the safest and most effective treatments for patients dealing with chronic immune disorders.

Download or read book Cellular and Molecular Toxicology of Nanoparticles written by Quaiser Saquib and published by Springer. This book was released on 2018-02-16 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types. Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs exposure has been included. The readers are also introduced to the less studied topic on the adsorption of biomolecules (mainly proteins) on the NPs surface, constituting the so-called “biomolecular corona”. The book has been designed for scientists engaged in NPs toxicity research. Nonetheless, it should be of interest to a variety of scientific disciplines including marine biology, environmental pollution, genetics, pharmacology, medicine, drug and food material sciences, consumer products. Also, the compilations will be of interest to the environmental watchdogs, federal regulators, risk assessors and the policy makers.

Download or read book The China Population and Labor Yearbook written by Fang Cai and published by BRILL. This book was released on 2012-02-17 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This English-language volume is an edited collection of articles from the 2010 Chinese-language volume of the Green Book of Population and Labor. It examines recent developments in the Chinese demographic transition and its implications, especially for the labor market.

Download or read book Report of the Chief Inspector of the Bureau for the Safe Transportation of Explosives and Other Dangerous Articles written by American Railway Association. Bureau of Explosives and published by . This book was released on 1910 with total page 1062 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Placental Signals written by Lise Cédard and published by Boydell & Brewer. This book was released on 1992 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third meeting of the European Placenta Group and the Rochester Trophoblast Conference in 1989 was concerned with placental communication; this volume presents selected contributions from the meeting, in four thematic sections: Growth, Differentiation, and Establishment of Pregnancy; Signals which regulate Placental Gonadotropin and Lactogen Secretion; Trophoblastic Signal Mechanisms, and Signals and Placental Vasculature.

Download or read book ADME and Translational Pharmacokinetics Pharmacodynamics of Therapeutic Proteins written by Honghui Zhou and published by John Wiley & Sons. This book was released on 2015-10-26 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain

Download or read book Providence Magazine written by and published by . This book was released on 1923 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: