Download or read book Test No 437 Bovine Corneal Opacity and Permeability Test Method for Identifying Ocular Corrosives and Severe Irritants written by OECD and published by OECD Publishing. This book was released on 2009-09-08 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bovine Corneal Opacity and Permeability test method (BCOP) is an in vitro test method that can be used to classify substances as 'ocular corrosives and severe irritants'. The BCOP uses isolated corneas from the eyes of cattle slaughtered for ...
Download or read book Test No 405 Acute Eye Irritation Corrosion written by OECD and published by OECD Publishing. This book was released on 2002-04-24 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...
Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 492 Reconstructed human Cornea like Epithelium RhCE test method for identifying chemicals not requiring classification and labelling for eye irritation or serious eye damage written by OECD and published by OECD Publishing. This book was released on 2024-06-25 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vitro procedure allowing the identification of chemicals (substances and mixtures) not requiring classification and labelling for eye irritation or serious eye damage in accordance with UN GHS.
Download or read book Ecotoxicology of Nanoparticles in Aquatic Systems written by Julian Blasco and published by CRC Press. This book was released on 2019-07-19 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of nanoparticles in medicine, industrial, and other applications has triggered an interest in their potential. This book explores the use of nanoparticles related to their occurrence in the environment, their impact on biota in aquatic systems, application of new methodologies, and changes associated with new global scenarios. The book also covers the bioaccumulation and internalization of nanoparticles as key aspects to assess their uptake and discusses the methodologies for testing ENPs ecotoxicity at different trophic levels.
Download or read book Code of Federal Regulations written by and published by . This book was released on 2017 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Special edition of the Federal Register, containing a codification of documents of general applicability and future effect ... with ancillaries.
Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 467 Defined Approaches for Serious Eye Damage and Eye Irritation written by OECD and published by OECD Publishing. This book was released on 2024-06-25 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline proposes defined approaches (DA) combining data generated in vitro methods, with information sources such as physicochemical properties.
Download or read book Cosmetic Formulation written by Heather A.E. Benson and published by CRC Press. This book was released on 2019-04-05 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cosmetics are the most widely applied products to the skin and include creams, lotions, gels and sprays. Their formulation, design and manufacturing ranges from large cosmetic houses to small private companies. This book covers the current science in the formulations of cosmetics applied to the skin. It includes basic formulation, skin science, advanced formulation, and cosmetic product development, including both descriptive and mechanistic content with an emphasis on practical aspects. Key Features: Covers cosmetic products/formulation from theory to practice Includes case studies to illustrate real-life formulation development and problem solving Offers a practical, user-friendly approach, relying on the work of recognized experts in the field Provides insights into the future directions in cosmetic product development Presents basic formulation, skin science, advanced formulation and cosmetic product development
Download or read book Code of Federal Regulations Title 29 Labor Pt 1910 Sec 1910 1000 End of Pt 1910 Revised As of July 1 2012 written by Office of the Federal Register (U.S.) Staff and published by Government Printing Office. This book was released on 2012-09-17 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Title 29 Labor Part 1910 1910 1000 to end of part 1910 Revised as of July 1 2013 written by Office of The Federal Register, Enhanced by IntraWEB, LLC and published by IntraWEB, LLC and Claitor's Law Publishing. This book was released on 2014-07-01 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Code of Federal Regulations Title 29 contains the codified Federal laws and regulations that are in effect as of the date of the publication pertaining to labor, including employment, wages and mediation.
Download or read book Handbook of Cosmetic Science and Technology written by André O. Barel and published by CRC Press. This book was released on 2014-04-09 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experienced and internationally renowned contributors, this is the fourth edition of what has become the standard reference for cosmetic scientists and dermatologists seeking the latest innovations and technology for the formulation, design, testing, use, and production of cosmetic products for skin, hair, and nails. New to this fourth e
Download or read book The History of Alternative Test Methods in Toxicology written by and published by Academic Press. This book was released on 2018-10-20 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement,Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated, miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing, capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialized areas, such as inhalation toxicity studies. The History of Alternative Test Methods in Toxicology uses a chronological approach to demonstrate how the use of alternative methods has evolved from their conception as adjuncts to traditional animal toxicity tests to replacements for them. This volume in the History of Toxicology and Environmental Health series explores the history of alternative test development, validation, and use, with an emphasis on humanity and good science, in line with the Three Rs (Replacement, Reduction, Refinement) concept expounded by William Russell and Rex Burch in 1959 in their now-classic volume, The Principles of Humane Experimental Technique. The book describes the historical development of technologies that have influenced the application of alternatives in toxicology and safety testing. These range from single cell monocultures to sophisticated miniaturised and microfluidic organism-on-a-chip devices, and also include molecular modelling, chemoinformatics and QSAR analysis, and the use of stem cells, tissue engineering and hollow fibre bioreactors. This has been facilitated by the wider availability of human tissues, advances in tissue culture, analytical and diagnostic methods, increases in computational processing capabilities, and a greater understanding of cell biology and molecular mechanisms of toxicity. These technological developments have enhanced the range and information content of the toxicity endpoints detected, and therefore the relevance of test systems and data interpretation, while new techniques for non-invasive diagnostic imaging and high resolution detection methods have permitted an increased role for human studies. Several key examples of how these technologies are being harnessed to meet 21st century safety assessment challenges are provided, including their deployment in integrated testing schemes in conjunction with kinetic modelling, and in specialised areas, such as inhalation toxicity studies.
Download or read book OECD Series on Testing and Assessment Second Edition Guidance Document on Integrated Approaches to Testing and Assessment IATA for Serious Eye Damage and Eye Irritation written by OECD and published by OECD Publishing. This book was released on 2019-07-25 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document suggests an Integrated Approach on Testing and Assessment (IATA) for serious eye damage and eye irritation hazard identification. The document also provides key information characteristics of each of the individual information sources comprising the IATA. Furthermore it provides guidance on how and when to integrate existing and/or newly generated information for decision making, including decisions on the need for further testing or final decisions on classification and labelling regarding the potential eye hazard effects of test chemicals.
Download or read book OECD Guidelines for the Testing of Chemicals Section 4 Test No 405 Acute Eye Irritation Corrosion written by OECD and published by OECD Publishing. This book was released on 2023-07-04 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...
Download or read book Hamilton and Hardy s Industrial Toxicology written by Raymond D. Harbison and published by John Wiley & Sons. This book was released on 2015-04-13 with total page 1364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a concise, yet comprehensive, reference on all aspects of industrial exposures and toxicants; this book aids toxicologists, industrial hygienists, and occupational physicians to investigate workplace health problems. • Updates and expands coverage with new chapters covering regulatory toxicology, toxicity testing, physical hazards, high production volume (HPV) chemicals, and workplace drug use • Includes information on occupational and environmental sources of exposure, mammalian toxicology, industrial hygiene, medical management and ecotoxicology • Retains a succinct chapter format that has become the hallmark for the previous editions • Distils a vast amount of information into one resource for both academics and professionals
Download or read book In Vitro Toxicology written by Alok Dhawan and published by Academic Press. This book was released on 2017-11-13 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Vitro Toxicology details the protocols and methods of in vitro testing, highlighting the usefulness of models, methods and the cost-effectiveness and reproducibility of such methodologies. The current approaches and strategies required to develop an easy, reliable, validated and high throughput system for use in alternative animal models to circumvent in vivo testing are discussed in detail. The book also includes chapters on the principles involved in the general selection and use of models that address safety concerns, regulatory acceptance and the current understandings and strategies for the identification of biomarkers in toxicity testing. Furthermore, principles involved in the general selection and use of models that address the issues of safety concerns and regulatory acceptance of these models are discussed, making the book beneficial to students, scientists, and regulators working in toxicology, as well as those in the field of chemicals and the safety assessment of novel materials. Discusses new techniques and protocols in a clear and concise manner includes examinations of nanotoxicity, genotoxicity and carcinogenicity Explains practical laboratory methods and the theories behind in vitro testing
Download or read book A Practical Guide to Toxicology and Human Health Risk Assessment written by Laura Robinson and published by John Wiley & Sons. This book was released on 2018-11-20 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology – the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people. The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author's training courses and webinars, leading to this valuable book. Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment. Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.
Download or read book Federal Register written by and published by . This book was released on 2012-07 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt:
