Download or read book Test No 310 Ready Biodegradability CO2 in sealed vessels Headspace Test written by OECD and published by OECD Publishing. This book was released on 2006-07-11 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline is a screening method for the evaluation of ready biodegradability of chemical

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 310 Ready Biodegradability CO2 in sealed vessels Headspace Test written by OECD and published by OECD Publishing. This book was released on 2014-09-26 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline is a screening method for the evaluation of ready biodegradability of chemicals.

Download or read book Standard Test Method for Determining Ready Ultimate Biodegradability of Organic Chemicals in a Sealed Vessel CO2 Production Test written by and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 319A Determination of in vitro intrinsic clearance using cryopreserved rainbow trout hepatocytes RT HEP written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of cryopreserved rainbow trout (Oncorhynchus mykiss) hepatocytes (RT-HEP) as a metabolising system to determine the clearance (CL, IN VITRO, INT) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-HEP ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 242 Potamopyrgus antipodarum Reproduction Test written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 23 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Potamopyrgus antopodarumon reproduction test is designed to assess potential effects of prolonged exposure to chemicals on reproduction and survival of parthenogenetic lineages of the freshwater mudsnail Potamopyrgus antipodarum. Adult female P. antipodarum are exposed to a concentration ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 305 Bioaccumulation in Fish Aqueous and Dietary Exposure written by OECD and published by OECD Publishing. This book was released on 2012-10-02 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a procedure for characterising the bioconcentration potential of substances in fish, using an aqueous (standard and minimised tests) or dietary exposure, under flow-through conditions (but semi-static regimes are ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 250 EASZY assay Detection of Endocrine Active Substances acting through estrogen receptors using transgenic tg cyp19a1b GFP Zebrafish embrYos written by OECD and published by OECD Publishing. This book was released on 2021-06-17 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: The EASZY assay is a mechanism-based in vivo screening assay designed to detect endocrine active chemicals acting as agonist through estrogen receptors (ERs), by inducing the expression of the green fluorescent protein (GFP) driven by the cyp19a1b promoter. The EASZY assay allows for the detection of estrogenic activity of chemicals on transgenic tg(cyp19a1b:GFP) Zebrafish embryos exposed for 96 hours during the embryonic stages of development.

Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 243 Lymnaea stagnalis Reproduction Test written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 31 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline is designed to assess effects of prolonged exposure to chemicals on the reproduction and survival of the hermaphrodite freshwater snail Lymnaea stagnalis (the Great Pond Snail).

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 319B Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub cellular fraction RT S9 written by OECD and published by OECD Publishing. This book was released on 2018-06-27 with total page 36 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 241 The Larval Amphibian Growth and Development Assay LAGDA written by OECD and published by OECD Publishing. This book was released on 2015-07-28 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes the Medaka Extended One Generation Test (MEOGRT), which exposes fish over multiple generations to give data relevant to ecological hazard and risk assessment of chemicals, including suspected endocrine disrupting chemicals (EDCs). Exposure in the MEOGRT starts with ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 248 Xenopus Eleutheroembryonic Thyroid Assay XETA written by OECD and published by OECD Publishing. This book was released on 2019-06-18 with total page 42 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of the test is to measure the capacity of a chemical to activate or inhibit the transcription of a genetic construct (THb/ZIP-GFP X. laevis eleutheroembryos) either by binding to the thyroid hormone receptor or by modifying the amount of thyroid hormone available for transcription. The test is based on the use of a transgenic frog (possessing the genetic construction THb/ZIP-GFP) of the species X. laevis. GFP is a fluorescent protein that can be used to affirm the presence of the substance and to follow its action. This test is based on the quantification of fluorescence, and thus of the GFP protein, throughout the eleutheroembryo exposed to a test chemical. Indeed, if the fluorescence is > 12% by including the highest concentration of the test, the test is considered positive. Organisms are exposed in chemically inert cell culture plates (6 wells). Each well contains ten organisms in solution. In a run, 20 organisms are exposed to each test concentration. Tadpoles are exposed to the test chemical at NF stage 45 for a duration of 72 hours. A positive result of the XETA test indicates in vivo that a substance induces damage to the receptor and metabolization of the thyroid hormone. A negative result indicates that, under test conditions, the test substance does not induce detectable damage to the thyroid and its functioning.

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Test No 314 Simulation Tests to Assess the Biodegradability of Chemicals Discharged in Wastewater written by OECD and published by OECD Publishing. This book was released on 2008-10-16 with total page 51 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes a method to assess the extent and kinetics of primary and ultimate biodegradation of organic chemicals whose route of entry into the environment begins with their discharge to wastewater. It consists of five simulation ...

Download or read book OECD Guidelines for the Testing of Chemicals Section 3 Degradation and Accumulation Revised Introduction to the OECD Guidelines for Testing of Chemicals Section 3 written by OECD and published by OECD Publishing. This book was released on 2006-09-11 with total page 17 pages. Available in PDF, EPUB and Kindle. Book excerpt: The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, industry and independent laboratories to identify and characterise potential hazards of chemicals. They are a set of tools for professionals, used primarily in regulatory safety testing and subsequent chemical and chemical product notification, chemical registration and in chemical evaluation. They can also be used for the selection and ranking of candidate chemicals during the development of new chemicals and products and in toxicology research. This group of tests covers environmental fate and behaviour. In 2017, the section 3 "Degradation and Accumulation" was renamed to " Environmental fate and behaviour" to take into account Test Guidelines measuring endpoints such as dispersion, aggregation.

Download or read book Human and Ecological Risk Assessment written by Dennis J. Paustenbach and published by John Wiley & Sons. This book was released on 2024-04-15 with total page 1319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand the fundamentals of human risk assessment with this introduction and reference Human risk assessments are a precondition for virtually all industrial action or environmental regulation, all the more essential in a world where chemical and environmental hazards are becoming more abundant. These documents catalog potential environmental, toxicological, ecological, or other harms resulting from a particular hazard, from chemical spills to construction projects to dangerous workplaces. They turn on a number of variables, of which the most significant is the degree of human exposure to the hazardous agent or process. Human and Ecological Risk Assessment combines the virtues of a textbook and reference work to introduce and analyze these vital documents. Beginning with the foundational theory of human health risk assessment, it then supplies case studies and detailed analysis illustrating the practice of producing risk assessment documents. Fully updated and authored by leading authorities in the field, the result is an indispensable work. Readers of the second edition of Human and Ecological Risk Assessment will also find: Over 40 entirely new case studies reflecting the latest in risk assessment practice Detailed discussion of hazards including air emissions, contaminated food and soil, hazardous waste sites, and many more Case studies from multiple countries to reflect diverse international standards Human and Ecological Risk Assessment is ideal for professionals and advanced graduate students in toxicology, industrial hygiene, occupational medicine, environmental science, and all related subjects.

Download or read book OECD Guidelines for the Testing of Chemicals Section 2 Test No 251 Rapid Androgen Disruption Activity Reporter RADAR assay written by OECD and published by OECD Publishing. This book was released on 2022-06-30 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Rapid Androgen Disruption Activity Reporter (RADAR) Test Guideline describes an aquatic assay that utilizes transgenic Oryzias latipes (O. latipes, Japanese medaka) eleutheroembryos at day post hatch zero, in a multi-well format to detect chemicals active on the androgen axis.

Download or read book Introduction to Toxicological Screening Methods and Good Laboratory Practice written by Saravana Babu Chidambaram and published by Springer Nature. This book was released on 2022-02-11 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the principles, methods, and interpretation involved in establishing the safety, risk, and hazard assessment of small molecules. It presents the regulatory requirements for risk and hazard identification as per the guidelines of the Organization for Economic Cooperation and Development (OECD), Paris, and the International Council for Harmonisation (ICH) of Technical Requirements for Pharmaceuticals for Human Use ICH and Schedule ‘Y’, India. It serves as reference material for undergraduate and postgraduate pharmacy degree students as well as senior researchers to learn about the principles, methods, and interpretations of systemic dosage (acute and repeated dose) and genotoxicity (in vitro and in vivo), special toxicological investigations such as reproductive and developmental toxicology, carcinogenicity, and toxicokinetics using animal models or in vitro methods, as applicable. This book is the first of its kind in providing information on the principles and methods of implementation of Good Laboratory Practice based on the guidelines of OECD. It includes detailed chapters about the regulatory requirements and guidelines in pharmaceutical products and agrochemicals. It also describes the infrastructure needed for preclinical studies, including in vivo and in vitro facilities.

Download or read book Biodegradable Polymer Based Food Packaging written by Abhishek Dutt Tripathi and published by Springer Nature. This book was released on 2022-10-20 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers different aspects of biodegradable packaging, such as their sourcing and application in food industries. The book focuses on the production and characterization of biodegradable food packaging derived from plant, animal and microbial sources. Chapters highlight the nano-technological interventions in biodegradable food packaging and the less studied microbial biopolymer-based biodegradable food packaging makes it distinct from other related books. It includes the latest research and development in the areas of food processing, food packaging, material science and polymeric science. It also discusses the standards and regulatory guidelines about the biodegradability testing of these polymers. This book is meant for researchers in food science, food packaging, bioprocess technology, polymer science and biochemical engineering. It is also beneficial for faculty members and students of food microbiology, food technology, dairy technology. The book is also meant for small entrepreneurs and farmers who are interested in bio-plastic usage for food packaging.