Download or read book Tertiary Lymphoid Organs TLOs Powerhouses of Disease Immunity written by Changjun Yin and published by Frontiers Media SA. This book was released on 2017-05-22 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.
Download or read book Tertiary Lymphoid Organs TLOs Powerhouses of Disease Immunity written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.
Download or read book Lymphoid Organs Advances in Immunology written by Quinn Houghton and published by Foster Academics. This book was released on 2023-09-26 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphoid organs are comprised of lymphoid tissue and are the site of lymphocyte activation and lymphocyte production. The structure of lymphoid organs includes primary lymphoid organs, secondary lymphoid organs and tertiary lymphoid organs. Primary lymphoid organs produce lymphocytes, the spleen and lymph nodes, through immature progenitor cells. Secondary lymphoid organs maintain mature lymphocytes, while initiating adaptive immune response. Tertiary lymphoid organs (TLOs) develop in peripheral tissues in adult organisms as a response to non-resolving inflammation. TLOs related diseases include chronic infection, allograft rejection, cancer and autoimmune diseases. They contain an active germinal center which is surrounded by a network of follicular dendritic cells (FDCs). The lymphatic system as a whole provides accessory return route for the blood. Furthermore, immune defense is another significant function of the lymphatic system. This book is a compilation of chapters that discuss the most vital advances in the field of Immunology with respect to lymphoid organs. It will provide comprehensive knowledge to the readers.
Download or read book Inducible Lymphoid Organs written by Kenji Kabashima and published by Springer Nature. This book was released on 2020-08-17 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book sheds new light on “inducible” lymphoid organs (ILOs): antigen presentation sites that are generated de novo in peripheral tissues under various pathogenic conditions. Accomplished immunologists demonstrate that the physiological role of these ILOs is completely different from that of central lymphoid organs, i.e., the lymph nodes or spleen. In addition to the central organs, the ILOs are considered essential structures for the efficient elicitation of adaptive immune responses in lesions. The respective chapters highlight examples from multiple sites, e.g. the skin, lung, intestinal tract, genital tract, the synovial membrane of the joints and artificial lymph nodes. Accordingly, readers will learn that ILO structure and function can vary substantially, depending on the context. Presenting the results of the latest immunological research, the book offers a fascinating and insightful read for both scientists and clinicians in the areas of infectious and immune-associated diseases.
Download or read book Tertiary Lymphoid Structures written by Marie-Caroline Dieu-Nosjean and published by Humana Press. This book was released on 2018-09-05 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores the various methods used to study tertiary lymphoid structures (TLS) in pathological situations. Pre-clinical models are also discussed in detail to show how TLS structure, development, and maintenance can be targeted and studied in vivo. The chapters in this book cover topics such as humans and mice; strategies to quantify TLS in order to use it in stained tissue sections; classifying a gene signature form fixed and paraffin-embedded tissues; and development of murine inflammatory models to help look at TLS in the context of infection or malignancy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Tertiary Lymphoid Structures: Methods and Protocols is a valuable resource that increases the reader’s knowledge on immune functions and how they will pave the way to future therapeutic applications.
Download or read book Gut and Physiology Syndrome written by Dr. Natasha Campbell-McBride, M.D. and published by Chelsea Green Publishing. This book was released on 2020-12-05 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Companion volume to the bestselling Gut & Psychology Syndrome—the book that launched the GAPS diet—which has been translated into 22 languages and sold more than 300,000 copies. Since the publication of the first GAPS book, Gut and Psychology Syndrome, in 2004, the GAPS concept has become a global phenomenon. People all over the world have been using the GAPS Nutritional Protocol for healing from physical and mental illnesses. The first GAPS book focused on learning disabilities and mental illness. This new book, Gut and Physiology Syndrome, focuses on the rest of the human body and completes the GAPS concept. Allergies, autoimmune illness, digestive problems, neurological and endocrine problems, asthma, eczema, chronic fatigue syndrome and fibromyalgia, psoriasis and chronic cystitis, arthritis and many other chronic degenerative illnesses are covered. Dr. Campbell-McBride believes that the link between physical and mental health, the food and drink that we take, and the condition of our digestive system is absolute. The clinical experience of many holistic doctors supports this position.
Download or read book Proceedings of joint event on 22nd Edition of International Conference on Immunology and Evolution of Infectious Diseases 12th Edition of International Conference on Tissue Engineering and Regenerative Medicine 2018 written by EuroScicon and published by EuroScicon. This book was released on 2018-05-04 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: May 10-11, 2018 | Frankfurt, Germany Key Topics : Classical Immunology, Immunomics, Immunoinformatics, Immune Checkpoints, Immune Adverse Effects, Immunological Disorders, Discipline Of Medicine, Upheaval In Cellular Immunology, Technological Novelty Of Immunology, Remedy For Immunity And Infection, Specificity And Cross Reactivity, Immunological Variability, Diagnosis Of Infection, Emerging And Re-Emerging Infectious Diseases, Immunology Of Infectious Diseases, Infectious Disease Drivers, Industrial Immunology, Versatile Immunology, Study Of Evolution, Clinical Immunology, Microbiology And Clinical Infections, Diagnostics Of Immunology, Immunity And Host Defence, Tissue Engineering, Regenerative Medicine, Regenerative Treatment Models, Soft Tissue Replacement, Cell Therapy, Stem Cell Bioprocessing, Immunomodulation Therapy, Regenerative Rehabilitation, Anti-Aging Medicine, Biomedicine, Biomedical Engineering Techniques, Biomaterials, Artificial Organ, Applications Of Tissue Engineering, Ethical Challenge And Clinical Issues, commercialization,
Download or read book Advances in Clinical Chemistry written by and published by Academic Press. This book was released on 2019-10-24 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Clinical Chemistry, Volume 93, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New chapters in this release include Lectin biosensors in cancer glycan biomarker detection, Cytokines in heart failure, Recent advances in the determination of insulins from biological fluids, Biomarkers in aggression, Evaluation of analytical performance of immunoassay methods for cTnI and cTnT: From theory to practice, Periodontal disease: From the lenses of light microscopy to the specs of proteomics and next generation sequencing, and more. - Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science - Authored by world renowned clinical laboratory scientists, physicians and research scientists - Presents the international benchmark for novel analytical approaches in the clinical laboratory
Download or read book Inflammation and Atherosclerosis written by Georg Wick and published by Springer Science & Business Media. This book was released on 2011-12-03 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis. More recently, it has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role. In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.
Download or read book Atherosclerosis written by Luigi Gianturco and published by BoD – Books on Demand. This book was released on 2018-08-01 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis is a subject of enormous contention for cardiologists and in general for all medical doctors. With this publication we have given you a concise "state-of-the-art" look at the world of atheroma. Many other elements could be included and so it is only a brief analysis of "today" (the preventive medicine era) and "tomorrow" (transforming the cure medicine era into the care medicine era) but also remembering "yesterday" (the ex-cathedra medicine era). Let's hope our arteries are free from atherosclerotic events: have a good read!
Download or read book Management of Penile Cancer written by Daniel J. Culkin and published by Springer Science & Business Media. This book was released on 2014-04-04 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Management of Penile Cancer provides a comprehensive and state-of-the-art overview of the major issues specific to the field of penile cancer. The sections of the book are structured to review the overall scope of issues of penile cancer, including diagnosis and staging, surgical approaches and the treatment of advanced disease. As multidisciplinary care is an integral part of the treatment of penile cancer, this book is unique in the inclusion of collaborating authors from a variety of integrated disciplines, including urology, radiation oncology, medical oncology and reconstructive surgery. Written by recognized experts in their field, Management of Penile Cancer is a unique and valuable resource in the field of penile cancer, both for those currently in training and for those already in clinical or research practice.
Download or read book Synthetic Immunology written by Takeshi Watanabe and published by Springer. This book was released on 2016-06-09 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the emerging studies of synthetic immunology, including the development and regeneration of immune cells, immune organ development and artificial regeneration, and the synthetic approach towards understanding human immune system. Immunology has developed rapidly over the last 50 years through the incorporation of new methods and concepts in cell and molecular biology, genetics, genomics and proteomics. This progress is the result of works by many excellent researchers all over the world. Currently, immunological research has accumulated detailed knowledge on basic mechanisms of immunity and is in the process to change medical practices. Yet, due to the enormous complexity of the immune system, many aspects on the regulation and function of this system remain unknown. Synthetic biology uses gain-of-function rather than loss-of-function approaches. The goals of synthetic biology can be described in a simple phrase “rebuild, alter, and understand,” namely, to rebuild minimal functional systems using well-defined parts from nature and then to perturb the system to understand its working principles. Given the richness of accumulated knowledge in molecular and cellular mechanisms of the immune system, we now begin adapting the concepts of synthetic biology to immunology. An immune response is a spatiotemporal phenomenon occurring at a given time and at a specialized place in the body. One goal of synthetic immunology is to reconstruct artificial microenvironments for better understanding of an immune response. We hope this yet-to-be-experimental approach of synthetic immunology and the compilation of this book will aid our further understanding of the immune system and future devising the tools to manipulate the immune system for therapy and prevention of the diseases.
Download or read book Ontogeny and Phylogeny of the Vertebrate Heart written by David Sedmera and published by Springer Science & Business Media. This book was released on 2012-06-23 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of reviews will be of considerable interests to biologists and MDs working on any aspect of cardiovascular function. With state-of-the-art reviews written by competent experts in the field, the content is also of interest for MSc and PhD students in most fields of cardiovascular physiology.
Download or read book A History of the Discovery of the Circulation of the Blood written by Pierre Flourens and published by . This book was released on 1859 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Surgical Recall written by Lorne H. Blackbourne and published by Lippincott Williams & Wilkins. This book was released on 2011-11-11 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its Sixth Edition, Surgical Recall allows for rapid-fire review of surgical clerkship material for third- or fourth-year medical students preparing for the USMLE and shelf exams. Written in a concise question-and-answer format—double-column, question on the left, answer on the right—Surgical Recall addresses both general surgery and surgical subspecialties. Students on rotation or being PIMPed can quickly refer to Surgical Recall for accurate and on-the-spot answers. The book includes survival tactics and tips for success on the boards and wards as well as key information for those new to the surgical suite.
Download or read book Mucosal Vaccines written by David W. Pascual and published by Academic Press. This book was released on 2019-10-19 with total page 941 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mucosal Vaccines: Innovation for Preventing Infectious Diseases discusses basic knowledge and discovery in the area of mucosal immunology and its related scientific fields. This completely updated, revised and authoritative treatise covers all aspects of mucosal vaccines, including their development, mechanisms of action, molecular/cellular aspects and practical applications. The book is organized in a unique format with basic, clinical and practical aspects described and discussed. The accumulated knowledge and new discoveries on the development of mucosal vaccines are logically introduced and discussed in an easy-to-understand format. - Provides the latest views on mucosal vaccines - Applies basic and current principles in the field of mucosal immunology and related scientific fields (e.g., microbiology, infectious diseases, systems biology, medicine, dentistry, veterinary medicine and translational research) to the development of new vaccines - Links basic, clinical and practical aspects of mucosal vaccines to different infectious diseases - Presents user-friendly organization using attractive illustrations
Download or read book Angiogenesis Lymphangiogenesis and Clinical Implications written by G. Marone and published by Karger Medical and Scientific Publishers. This book was released on 2013-10-21 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis, the formation of new blood vessels, is fundamental for physiological processes such as embryonic and postnatal development, wound repair, and reproductive functions. Angiogenesis plays a major role in tumor growth and in several autoimmune and allergic disorders. Lymphangiogenesis, the formation of new lymphatic vessels, is also important for tumor growth, the formation of metastasis, and chronic inflammatory diseases. Judah Folkman, a pioneer in the study of angiogenesis, first proposed that macrophages and mast cells could be a relevant source of angiogenic factors. Since then, much effort has gone into the elucidation of the role of immune cells in the modulation of angiogenesis and lymphangiogenesis. There is now compelling evidence that several components of the innate and adaptive immune system are implicated in inflammatory and neoplastic angiogenesis and lymphangiogenesis. Articles in this volume deal with the emerging, intriguing possibility that immune cells are both a source and a target of angiogenic and lymphangiogenic factors. Therefore, cells of the immune system might play a role in inflammatory and neoplastic angiogenesis/lymphangiogenesis through the expression of several angiogenic factors and their receptors and co-receptors. The important new findings in this volume will be of special interest to vascular biologists, basic and clinical immunologists, oncologists and to specialists in allergic and immune disorders.
