Download or read book A Proposal to End the COVID 19 Pandemic written by Ruchir Agarwal and published by International Monetary Fund. This book was released on 2021-05-19 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: Urgent steps are needed to arrest the rising human toll and economic strain from the COVID-19 pandemic that are exacerbating already-diverging recoveries. Pandemic policy is also economic policy as there is no durable end to the economic crisis without an end to the health crisis. Building on existing initiatives, this paper proposes pragmatic actions at the national and multilateral level to expeditiously defeat the pandemic. The proposal targets: (1) vaccinating at least 40 percent of the population in all countries by the end of 2021 and at least 60 percent by the first half of 2022, (2) tracking and insuring against downside risks, and (3) ensuring widespread testing and tracing, maintaining adequate stocks of therapeutics, and enforcing public health measures in places where vaccine coverage is low. The benefits of such measures at about $9 trillion far outweigh the costs which are estimated to be around $50 billion—of which $35 billion should be paid by grants from donors and the residual by national governments potentially with the support of concessional financing from bilateral and multilateral agencies. The grant funding gap identified by the Access to COVID-19 Tools (ACT) Accelerator amounts to about $22 billion, which the G20 recognizes as important to address. This leaves an estimated $13 billion in additional grant contributions needed to finance our proposal. Importantly, the strategy requires global cooperation to secure upfront financing, upfront vaccine donations, and at-risk investment to insure against downside risks for the world.
Download or read book Breast Cancer Metastasis and Drug Resistance written by Aamir Ahmad and published by Springer Nature. This book was released on 2019-08-27 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
Download or read book The Guide for the Perplexed written by Moses Maimonides and published by . This book was released on 1910 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Innovation in Pharmacy Advances and Perspectives September 2018 written by Organizer Committee IPAP18 – Salamanca and published by Ediciones Universidad de Salamanca. This book was released on 2018-09-21 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.
Download or read book Ecohealth Research in Practice written by Dominique F. Charron and published by Springer Science & Business Media. This book was released on 2011-11-25 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about doing innovative research to achieve sustainable and equitable change in people’s health and well-being through improved interactions with the environment. It presents experiences from the field of ecosystem approaches to health (or ecohealth research) and some insights and lessons learned. It builds on previous literature, notably Forget (1997), Forget and Lebel (2001), Lebel (2003), and Waltner-Toews et al. (2008). Through case-studies and other contributions by researchers supported by Canada’s International Development Research Centre (IDRC), the book presents evidence of real changes in conditions of people, their health, and the ecosystems that support them. These changes were derived from applications of an ecosystem approach to health in developing regions of the world. The book also illustrates the resulting body of applied, participatory, and action research that improved health and environmental management in developing countries and, in many cases, influenced policies and practices.
Download or read book Red October written by Jeffery R. Webber and published by BRILL. This book was released on 2011-09-20 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bolivia witnessed a left-indigenous insurrectionary cycle between 2000 and 2005 that overthrew two neoliberal presidents and laid the foundation for Evo Morales’ successful bid to become the country’s first indigenous head of state in 2006. Building on the theoretical traditions of revolutionary Marxism and indigenous liberation, this book provides an analytical framework for understanding the fine-grained sociological and political nuances of twenty-first century Bolivian class-struggle, state-repression, and indigenous resistance, as well the deeply historical roots of today’s oppositional traditions. Drawing on extensive ethnographic fieldwork, including more than 80 in-depth interviews with social-movement and trade-union activists, Red October is a ground-breaking intervention in the study of contemporary Bolivia and the wider Latin American turn to the left over the last decade.
Download or read book Toolkit for Counseling Spanish Speaking Clients written by Lorraine T. Benuto and published by Springer. This book was released on 2017-11-14 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely practical reference addresses the lack of Spanish-language resources for mental health professionals to use with their Latino clients. Geared toward both English- and Spanish-speaking practitioners in a variety of settings, this volume is designed to minimize misunderstandings between the clinician and client, and with that the possibility of inaccurate diagnosis and/or ineffective treatment. Coverage for each topic features a discussion of cultural considerations, guidelines for evidence-based best practices, a review of available findings, a treatment plan, plus clinical tools and client handouts, homework sheets, worksheets, and other materials. Chapters span a wide range of disorders and problems over the life-course, and include reproducible resources for: Assessing for race-based trauma. Using behavioral activation and cognitive interventions to treat depression among Latinos. Treating aggression, substance use, abuse, and dependence among Latino Adults. Treating behavioral problems among Latino adolescents. Treating anxiety among Latino children. Working with Latino couples. Restoring legal competency with Latinos. The Toolkit for Counseling Spanish-Speaking Clients fills a glaring need in behavioral service delivery, offering health psychologists, social workers, clinical psychologists, neuropsychologists, and other helping professionals culturally-relevant support for working with this under served population. The materials included here are an important step toward dismantling barriers to mental health care.
Download or read book Managing the Risks of Extreme Events and Disasters to Advance Climate Change Adaptation written by Intergovernmental Panel on Climate Change and published by Cambridge University Press. This book was released on 2012-05-28 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extreme weather and climate events, interacting with exposed and vulnerable human and natural systems, can lead to disasters. This Special Report explores the social as well as physical dimensions of weather- and climate-related disasters, considering opportunities for managing risks at local to international scales. SREX was approved and accepted by the Intergovernmental Panel on Climate Change (IPCC) on 18 November 2011 in Kampala, Uganda.
Download or read book Zoot Suit Other Plays written by Luis Valdez and published by Arte Publico Press. This book was released on 1992-04-30 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This critically acclaimed play by Luis Valdez cracks open the depiction of Chicanos on stage, challenging viewers to revisit a troubled moment in our nationÕs history. From the moment the myth-infused character El Pachuco burst onto the stage, cutting his way through the drop curtain with a switchblade, Luis Valdez spurred a revolution in Chicano theater. Focusing on the events surrounding the Sleepy Lagoon Murder Trial of 1942 and the ensuing Zoot Suit Riots that turned Los Angeles into a bloody war zone, this is a gritty and vivid depiction of the horrifying violence and racism suffered by young Mexican Americans on the home front during World War II. ValdezÕs cadre of young urban characters struggle with the stereotypes and generalizations of AmericaÕs dominant culture, the questions of assimilation and patriotism, and a desire to rebel against the mainstream pressures that threaten to wipe them out. Experimenting with brash forms of narration, pop culture of the war era, and complex characterizations, this quintessential exploration of the Mexican-American experience in the United States during the 1940Õs was the first, and only, Chicano play to open on Broadway. This collection contains three of playwright and screenwriter Luis ValdezÕs most important and recognized plays: Zoot Suit, Bandido! and I DonÕt Have to Show You No Stinking Badges. The anthology also includes an introduction by noted theater critic Dr. Jorge Huerta of the University of California-San Diego. Luis Valdez, the most recognized and celebrated Hispanic playwright of our times, is the director of the famous farm-worker theater, El Teatro Campesino.
Download or read book Forced from Home written by Women's Refugee Commission Staff and published by . This book was released on 2012-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cardiorenal Syndrome in Heart Failure written by W. H. Wilson Tang and published by Springer Nature. This book was released on 2019-08-26 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive manual reviews the management of cardiorenal syndrome in heart failure. Chapters are structured in a practically applicable and easy-to-follow format with realistic case vignettes and key clinical management questions and answers, followed by a brief discussion of underlying pathophysiological mechanisms of a patient with cardiorenal syndrome. Building from this case, key questions are posed that are relevant to the clinical management and then potential evidence-based treatment strategies are proposed. Topics covered include loop diuretic resistance in acute and chronic heart failure, abdominal congestion, low output failure and potential diuretic complications due to hyponatremia. Cardiorenal Syndrome in Heart Failure thoroughly reviews cardiorenal syndrome from the perspective of both the cardiologist and nephrologist. Its case-based approach makes it an ideal resource for both practising and trainee cardiology and nephrology practitioners.
Download or read book Handbook of Hazards and Disaster Risk Reduction written by Ben Wisner and published by Routledge. This book was released on 2012-03-29 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook provides a comprehensive statement and reference point for hazard and disaster research, policy making, and practice in an international and multi-disciplinary context. It offers critical reviews and appraisals of current state of the art and future development of conceptual, theoretical and practical approaches as well as empirical knowledge and available tools. Organized into five inter-related sections, this Handbook contains sixty-five contributions from leading scholars. Section one situates hazards and disasters in their broad political, cultural, economic, and environmental context. Section two contains treatments of potentially damaging natural events/phenomena organized by major earth system. Section three critically reviews progress in responding to disasters including warning, relief and recovery. Section four addresses mitigation of potential loss and prevention of disasters under two sub-headings: governance, advocacy and self-help, and communication and participation. Section five ends with a concluding chapter by the editors. The engaging international contributions reflect upon the politics and policy of how we think about and practice applied hazard research and disaster risk reduction. This Handbook provides a wealth of interdisciplinary information and will appeal to students and practitioners interested in Geography, Environment Studies and Development Studies.
Download or read book Oxidative Stress and Chronic Degenerative Diseases written by Jose Antonio Morales-Gonzalez and published by BoD – Books on Demand. This book was released on 2013-05-22 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work responds to the need to find, in a sole document, the affect of oxidative stress at different levels, as well as treatment with antioxidants to revert and diminish the damage. Oxidative Stress and Chronic Degenerative Diseases - a Role for Antioxidants is written for health professionals by researchers at diverse educative institutions (Mexico, Brazil, USA, Spain, Australia, and Slovenia). I would like to underscore that of the 19 chapters, 14 are by Mexican researchers, which demonstrates the commitment of Mexican institutions to academic life and to the prevention and treatment of chronic degenerative diseases.
Download or read book Report of the Joint National Committee on Detection Evaluation and Treatment of High Blood Pressure written by Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure and published by . This book was released on with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chosen in Christ to Be Saints written by Angel Rodriguez-Luno and published by Createspace Independent Publishing Platform. This book was released on 2014-01-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as a manual for the study of fundamental moral theology. It is addressed primarily to those who are undertaking a required course of study in Catholic theology at seminaries or ecclesiastical colleges. The editorial and typographical style, the choice of topics, and the extent of material covered are intended to meet the needs of such students. Nevertheless, we trust that the book will likewise be of interest for those who pursue theological and moral studies at a non specialist, though nonetheless serious level.
