Download or read book Temporal Processing In The Amygdalo Prefronto Dorsostriatal Network In Rats written by Lucille Tallot and published by . This book was released on 2015 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time is an essential dimension of life. It is necessary for coordinating movement, for communication, but also for decision-making. The principal goal of this work was to characterize the role of an amygdalo-prefronto-dorsostriatal network in the memorization and encoding of time in a rat model. Firstly, we described temporal behavior in a conditioned suppression task (i.e. the suppression of an instrumental lever-pressing response for food by the presentation of a cue associated with an aversive event), therefore showing a precise temporal control in Pavlovian aversive conditioning. Secondly, we measured local field potentials in our network of interest at the beginning of associative learning and after overtraining in the conditioned suppression task. In effect, motor temporal behavior requires a large number of training sessions to become optimum, but temporal learning happens very early in training. This study allowed us to characterize, using frequency analysis of oscillatory activities, neuronal correlates of time in this network both at the level of individual structures, but also in their interactions. Interestingly, these neural correlates were modified by the level of training. Finally, we demonstrated that juvenile rats (pre-weaning), with an immature prefrontal cortex and dorsal striatum, can memorize and discriminate temporal intervals, raising questions on the role of this amygdalo-prefronto-dorsostriatal network in temporal learning during development.

Download or read book Self Injurious Behavior in Individuals with Neurodevelopmental Conditions written by Frederick Furniss and published by Springer Nature. This book was released on 2020-01-30 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses self-injurious behavior (SIB) in individuals with various neurodevelopmental conditions (NDCs). It takes a cross-NDC perspective that synthesizes recent research on variability in incidence and presentation across NDCs and the natural history and neurobiology of SIB. Chapters examine implications for biobehavioral definitions of subtypes of SIB and provide a detailed guide to assessment and intervention using an integrated research-based model for individualized treatment. In addition, chapters present a practice-focused structure using case studies to illustrate clinical implications of research findings. The book concludes with a discussion of current directions in research and their potential to guide innovation in prevention and treatment of SIB. Topics featured in this handbook include: · Self-restraint among individuals who self-injure. · Self-injurious behavior in individuals with autism spectrum conditions. · Assessing and managing short-term effects of SIB. · Reducing risk of, and responding to, relapse following successful intervention with SIB. · Ethical issues associated with working with people who engage in self-injurious behaviors. Self-Injurious Behavior in Individuals with Neurodevelopmental Conditions is a must-have resource for researchers, clinicians and practitioners as well as graduate students in the fields of clinical child and school psychology, applied behavior analysis, pediatrics, social work, developmental psychology, behavioral therapy/rehabilitation, child and adolescent psychiatry, clinical psychology and psychiatry of adult intellectual disability, and special education.

Download or read book Neuromodulation in Psychiatry written by Clement Hamani and published by John Wiley & Sons. This book was released on 2016-01-26 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by an expert multidisciplinary team, Neuromodulation in Psychiatry is the first reference guide to address both invasive and non-invasive neuromodulation strategies used in psychiatry. Covers basic principles, technical aspects, clinical applications and ethical considerations Presents up-to-date evidence in comprehensive summaries suitable for all levels of experience Each technique is clearly explained along with its implications for real-world clinical practice Allows psychiatrists to make informed decisions regarding neuromodulation for their patients

Download or read book Neurobiology of Interval Timing written by Hugo Merchant and published by Springer. This book was released on 2014-10-30 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of how the brain processes temporal information is becoming one of the most important topics in systems, cellular, computational, and cognitive neuroscience, as well as in the physiological bases of music and language. During the last and current decade, interval timing has been intensively studied in humans and animals using increasingly sophisticated methodological approaches. The present book will bring together the latest information gathered from this exciting area of research, putting special emphasis on the neural underpinnings of time processing in behaving human and non-human primates. Thus, Neurobiology of Interval Timing will integrate for the first time the current knowledge of both animal behavior and human cognition of the passage of time in different behavioral context, including the perception and production of time intervals, as well as rhythmic activities, using different experimental and theoretical frameworks. The book will the composed of chapters written by the leading experts in the fields of psychophysics, functional imaging, system neurophysiology, and musicology. This cutting-edge scientific work will integrate the current knowledge of the neurobiology of timing behavior putting in perspective the current hypothesis of how the brain quantifies the passage of time across a wide variety of critical behaviors.

Download or read book Functional and Neural Mechanisms of Interval Timing written by Warren H. Meck and published by CRC Press. This book was released on 2003-03-24 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding temporal integration by the brain is expected to be among the premier topics to unite systems, cellular, computational, and cognitive neuroscience over the next decade. The phenomenon has been studied in humans and animals, yet until now, there has been no publication to successfully bring together the latest information gathered from

Download or read book Suggestions for Addressing Clinical and Non Clinical Issues in Palliative Care written by Marco Cascella and published by BoD – Books on Demand. This book was released on 2021-07-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data from the World Health Organization indicate that about 40 million people worldwide require palliative care each year. We must face this enormous problem with appropriate welfare policies and training of up-to-date and competent personnel. In this context, a book that collects the experiences of authors with diverse backgrounds, and operating in different settings of palliative care, can be added to the many editorial products on the subject. Over five sections, this volume addresses such topics as palliative care in children, infants, and gynecologic oncology patients; the role of the caregiver; the use of drugs; and ethics, organization, and policy issues. Although this book should not be considered as an exhaustive treatise on palliative care, the many topics covered and the experience and competence of the authors involved make it a useful tool for those who are already experts in the field as well as those who are studying this field.

Download or read book Subjective Time written by Valtteri Arstila and published by MIT Press. This book was released on 2021-12-14 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interdisciplinary perspectives on the feature of conscious life that scaffolds every act of cognition: subjective time. Our awareness of time and temporal properties is a constant feature of conscious life. Subjective temporality structures and guides every aspect of behavior and cognition, distinguishing memory, perception, and anticipation. This milestone volume brings together research on temporality from leading scholars in philosophy, psychology, and neuroscience, defining a new field of interdisciplinary research. The book's thirty chapters include selections from classic texts by William James and Edmund Husserl and new essays setting them in historical context; contemporary philosophical accounts of lived time; and current empirical studies of psychological time. These last chapters, the larger part of the book, cover such topics as the basic psychophysics of psychological time, its neural foundations, its interaction with the body, and its distortion in illness and altered states of consciousness. Contributors Melissa J. Allman, Holly Andersen, Valtteri Arstila, Yan Bao, Dean V. Buonomano, Niko A. Busch, Barry Dainton, Sylvie Droit-Volet, Christine M. Falter, Thomas Fraps, Shaun Gallagher, Alex O. Holcombe, Edmund Husserl, William James, Piotr Jaśkowski, Jeremie Jozefowiez, Ryota Kanai, Allison N. Kurti, Dan Lloyd, Armando Machado, Matthew S. Matell, Warren H. Meck, James Mensch, Bruno Mölder, Catharine Montgomery, Konstantinos Moutoussis, Peter Naish, Valdas Noreika, Sukhvinder S. Obhi, Ruth Ogden, Alan o'Donoghue, Georgios Papadelis, Ian B. Phillips, Ernst Pöppel, John E. R. Staddon, Dale N. Swanton, Rufin VanRullen, Argiro Vatakis, Till M. Wagner, John Wearden, Marc Wittmann, Agnieszka Wykowska, Kielan Yarrow, Bin Yin, Dan Zahavi

Download or read book Neurochemistry written by Thomas Heinbockel and published by BoD – Books on Demand. This book was released on 2014-04-23 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurochemistry is a flourishing academic field that contributes to our understanding of molecular, cellular and medical neurobiology. As a scientific discipline, neurochemistry studies the role of chemicals that build the nervous system, it explores the function of neurons and glial cells in health and disease, it discovers aspects of cell metabolism and neurotransmission, and it reveals how degenerative processes are at work in the nervous system. Accordingly, this book contains chapters from a variety of topics that fall into the following broad sections: I. Neural Membranes and Intracellular Signaling, II. Neural Processing and Intercellular Signaling, III. Growth, Development and Differentiation, and IV. Neurodegenerative Diseases. The book presents comprehensive reviews in these different areas written by experts in their respective fields. Neurodegeneration and neuronal diseases are featured prominently and are a recurring theme throughout most chapters. This book will be a most valuable resource for neurochemists and other scientists alike. In addition, it will contribute to the training of current and future neurochemists and, hopefully, will lead us on the path to curing some of the biggest challenges in human health.

Download or read book Ion and Molecule Transport in Lysosomes written by Bruno Gasnier and published by CRC Press. This book was released on 2020-06-09 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lysosomes are key subcellular organelles that regulate the cell function. Many of the essential activities of the cell are dependent on lysosomes. Dysfunction is linked to multiple diseases - storage disorders, neurodegeneration, immunological diseases and cancer. This book discusses concepts and methods used to study lysosome ion and small molecule transport. The contents will not only attract accomplished investigators in need of a broad review and synthesis of this important subject but will also appeal to young investigators and trainees needing to acquire comprehensive knowledge and technical skills working with lysosomal ion channels and small molecule transporters. Key selling features: Summarizes the endocellular role that lysosomes play with respect to cellular waste disposal Reviews essential cellular functions of lysosomes Explores how lysosome dysfunction is the cause of many metabolic disorders Examines how lysomes are involved in storage diseases Describes various technologies and methods used in lysosome research

Download or read book Introduction to Addiction written by George F. Koob and published by Academic Press. This book was released on 2019-06-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse.

Download or read book Emotion written by Annett Schirmer and published by SAGE Publications. This book was released on 2014-07-07 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emotion, by Annett Schirmer, is a comprehensive text that integrates traditional psychological theories and cutting-edge neuroscience research to explain the nature and role of emotions in human functioning. Written in an engaging style, the book explores emotions at the behavioral, physiological, mental, and neurofunctional (i.e., chemical, metabolic, and structural) levels, and examines each in a broad context, touching on different theoretical perspectives, regulatory processes, development, and culture, among others. Providing greater insight and depth than existing texts, the book offers a holistic view of the field, giving students a broader understanding of the mechanisms underlying emotions and enabling them to appreciate the role emotions play in their lives. In dedicated chapters, the text covers past and current theories of emotion, individual emotions and their bodily representation, the role of emotions for behavior and cognition, as well as interindividual differences.

Download or read book Death And Medical Power An Ethical Analysis Of Dutch Euthanasia Practice written by ten Have, Henk and published by McGraw-Hill Education (UK). This book was released on 2005-05-01 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book is a well-referenced review of the history of the societal debate, attempts at regulation, and the practice itself. In addition, it discusses important and insightful distinctions (active-passive; omission-commission; outcomes-intentions). The unique basis for their conclusion makes an outstanding contribution to the literature." Robert D. Orr, MD, CM, Professor of Bioethics,at Loma Linda University, California, USA. How have Dutch debates on end-of-life care developed so differently from most other countries, finally resulting in the legalization of euthanasia? What are the relevant legal, medical and ethical dimensions of euthanasia and physician assisted suicide? What lessons can be learned from the Dutch experience with euthanasia? In all modern countries a good death and relief of suffering are important issues of public debate. The bioethical debate in the Netherlands is unique since it has been focusing on the issue of euthanasia for more than thirty years. This book describes the debate, explains its origins, and analyses its development, resulting in the legislation of euthanasia. It also presents data on the medical practice of euthanasia with examples of cases. Death and Medical Power details the evolution as well as the complexities of the legal responses to physician involvement in euthanasia. The authors analyze the ethical debate concerning euthanasia, discussing the pros and cons of medical termination of human life. The book concludes with a section on the lessons to be learned from the Dutch experience. This unique study will be of relevance to all clinicians and other professionals involved in end-of-life care, to health policy makers and educators, as well as anybody else interested in the ethics of euthanasia.

Download or read book Society for Neuroscience Abstracts written by Society for Neuroscience. Annual Meeting and published by . This book was released on 1995 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Neuronal Oscillations of Wakefulness and Sleep written by Thien Thanh Dang-Vu and published by Springer. This book was released on 2021-05-30 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this work is to review recent findings highlighting the mechanisms and functions of the neuronal oscillations that structure brain activity across the sleep-wake cycle. An increasing number of studies conducted in humans and animals, and using a variety of techniques ranging from intracellular recording to functional neuroimaging, has provided important insight into the mechanisms and functional properties of these brain rhythms. Studies of these rhythms are fundamental not only for basic neuroscience, but also for clinical neuroscience. At the basic science level, neuronal oscillations shape the interactions between different areas of the brain and profoundly impact neural responses to the environment, thereby mediating the processing of information in the brain. At the clinical level, brain oscillations are affected in numerous neurological conditions and might provide useful biomarkers that inform about patients’ evolution and vulnerability. During sleep, these brain rhythms could provide functional support to internal states that govern the basic maintenance of local circuit and systemic interactions. During wake, the rhythmicity of cortical and subcortical circuits have been linked with sensory processing, cognitive operations, and preparation for action. This book will attempt to link together these sleep and wake functional roles at the level of neuroimaging and electroencephalographic measures, local field potentials, and even at the cellular level. ​

Download or read book Structure and Function of GPCRs written by Guillaume Lebon and published by Springer. This book was released on 2019-08-01 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces readers to the latest advances in G protein-coupled receptor (GPCR) biology. It reviews our current understanding of the structural basis of ligand binding and allosteric mechanisms, following a decade of technological breakthroughs. Several examples of structure-based drug discovery are presented, together with the future challenges involved in designing better drugs that target GPCRs. In turn, the book illustrates the important concept of GPCR biased signaling in physiological contexts, and presents fluorescent- and light-based methodologies frequently used to measure GPCR signaling or to trace their dynamics in cells upon ligand activation. Taken together, the chapters provide an essential overview and toolkit for new scientific investigators who plan to develop GPCR projects. All chapters were written by experts in their respective fields, and share valuable insights and powerful methodologies for the GPCR field.

Download or read book The Molecular Basis of Drug Addiction written by Shafiqur Rahman and published by Academic Press. This book was released on 2016-01-28 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Progress in Molecular Biology and Translational Science focuses on the molecular basis of drug addiction. - Contains contributions from leading authorities - Informs and updates on all the latest developments in the field

Download or read book Presynaptic Inhibition and Neural Control written by Pablo Rudomin and published by . This book was released on 1998 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a timely review of the mechanisms underlying the presynaptic control of synaptic transmission and the role they play in sensory and motor behavior. Early chapters offer a detailed account of the anatomy, biophysics, and physiology of synaptic transmission at the peripheral and centralsynapses, focusing on the presynaptic control of transmitter release. Later chapters explore the organization of neural pathways leading to the presynaptic inhibition of transmitter release in segmental reflex pathways. A final section provides examples of the operation of presynaptic controlmechanisms during specific sensory and motor functions in mammals, including humans. Integrating synaptic transmission and CNS functions at the systems level, this volume will be of particular interest to researchers studying both areas.