Download or read book Temporal Features in Resting State fMRI Data written by Xiaoping Philip Hu and published by Frontiers Media SA. This book was released on 2021-01-20 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Introduction to Variational Autoencoders written by Diederik P. Kingma and published by . This book was released on 2019-11-12 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Variational Autoencoders provides a quick summary for the of a topic that has become an important tool in modern-day deep learning techniques.
Download or read book Spatio temporal Dynamics of Human FMRI Resting Rate written by Katharina Glomb and published by . This book was released on 2016 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spontaneous brain activity, measured under the absence of any overt task, has been investigated under the label of "resting state" for about 20 years with rising interest. While it was known since the beginnings of modern electrophysiology that the brain exhibits spontaneous fluctuations also during rest, the discovery, in 1995, that these fluctuations possess a robust spatio-temporal structure had a profound impact on how we understand and investigate brain activity. In this dissertation, we characterize the spatio-temporal dynamics of resting state on a macroscopic level using fMRI recordings from humans and combining novel data analysis tools with theoretical models on the level of the whole brain. We demonstrate the presence of common patterns of functional connectivity, known as resting state networks (RSNs), that evolve in time in both empirical and model data. We show that spontaneous fluctuations and their statistics are determined by the structure of the brain network and its dynamics.
Download or read book Origins of the Resting State fMRI Signal written by Jean Chen and published by Frontiers Media SA. This book was released on 2020-12-28 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Toward Improved Characterization of Brain Network Temporal Properties with Functional Magnetic Resonance Imaging written by Catherine Elizabeth Chang and published by Stanford University. This book was released on 2011 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional magnetic resonance imaging (fMRI) based on blood-oxygen level dependent (BOLD) contrast is a powerful technique for non-invasive measurement of brain activity. Recent fMRI studies have revealed that the spontaneous BOLD fluctuations of the human brain organize into distributed, temporally-coherent networks ("resting-state networks"; RSNs). Examination of RSNs has yielded valuable insight into neural organization and development, and demonstrates potential as a biomarker for conditions such as Alzheimer's disease and depression. However, the accuracy by which the spatio-temporal properties of RSNs can be delineated using fMRI is compromised by the presence of physiological (cardiac and respiratory) noise and vascular hemodynamic variability. Further, our present understanding of how RSNs may interact and support cognitive function has been limited by the fact that the vast majority of studies to-date analyze RSNs in a manner that assumes temporal stationarity. Here, we describe efforts to correct for non-neural physiological influences on the BOLD signal, as well as investigations into the dynamic character of resting-state network connectivity. It is found that low-frequency variations in cardiac and respiratory processes account for significant noise across widespread gray matter regions, and that a constrained deconvolution approach may prove effective for modeling and reducing their effects. Application of the proposed noise-reduction procedure is observed to yield negative correlations between the spontaneous fluctuations of two major RSNs. The relationship between respiratory volume changes and the BOLD signal is further examined by simultaneously monitoring and comparing chest expansion data, end-tidal gas concentrations, and spontaneous BOLD fluctuations. The use of a breath-holding task is proposed for quantifying regional differences in BOLD signal timing that arise from local vasomotor response delays; such non-neural timing delays are found to impact inferences of resting-state connectivity and causality. Finally, a preliminary analysis of non-stationary connectivity between RSNs is performed using wavelet and sliding-window approaches, and it is observed that interactions between networks may reconfigure on time-scales of seconds to minutes.
Download or read book Hilbert huang Transform And Its Applications 2nd Edition written by Norden E Huang and published by World Scientific. This book was released on 2014-04-22 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is written for scientists and engineers who use HHT (Hilbert-Huang Transform) to analyze data from nonlinear and non-stationary processes. It can be treated as a HHT user manual and a source of reference for HHT applications. The book contains the basic principle and method of HHT and various application examples, ranging from the correction of satellite orbit drifting to detection of failure of highway bridges.The thirteen chapters of the first edition are based on the presentations made at a mini-symposium at the Society for Industrial and Applied Mathematics in 2003. Some outstanding mathematical research problems regarding HHT development are discussed in the first three chapters. The three new chapters of the second edition reflect the latest HHT development, including ensemble empirical mode decomposition (EEMD) and modified EMD.The book also provides a platform for researchers to develop the HHT method further and to identify more applications.
Download or read book Magnetoencephalography written by Selma Supek and published by Springer. This book was released on 2014-08-07 with total page 999 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.
Download or read book Selected Papers on Language and the Brain written by N. Geschwind and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: Philosophers of science work not only with the methods of the sciences but with their contents as well. Substantive issues concerning the relation between mind and matter, between the material basis and the functions of cognition, have been central within the entire history of philosophy. We recall such philosophers as Aristotle, Descartes, the early Kant, Ernst Mach, and the early William James as directly inquiring of the organs and structures of thinking. Science and its philosophical self-criticism are especially and deeply united in the effort to understand the biological brain and human behavior, and so it requires no apology to include this collection of clinical studies among Boston Studies in the Philosophy of Science. The work of Dr. Norman Geschwind, well represented in this selection, explores the relation between structure and function, between the anatomy of the brain and the 'higher' behavior of men and women. As a clinical neurologist, Geschwind was led to these studies particularly by his in terest in those pathologies which have to do with human perception and language. His research into the anatomical substrates of specific dis orders-and strikingly the aphasias -present a fascinating and provocative examination of fundamental questions which will concern not neurologists alone but also psychologists, physicians, linguists, speech pathologists, educators, anthropologists, historians of medicine, and philosophers, among others, namely all those interested in the characteristic modes of human activity, in speech, in perception, and in the learning process generally.
Download or read book Advances in Resting State Functional MRI written by Jean Chen and published by Elsevier. This book was released on 2023-07-03 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Resting-State Functional MRI: Methods, Interpretation, and Applications gives readers with basic neuroimaging experience an up-to-date and in-depth understanding of the methods, opportunities, and challenges in rs-fMRI. The book covers current knowledge gaps in rs-fMRI, including "what are biologically plausible brain networks," "how to tell what part is noise," "how to perform quality assurance on the data," "what are the spatial and temporal limits of our ability to resolve FC," and "how to best identify network features related to individual differences or disease state". This book is an ideal reference for neuroscientists, computational neuroscientists, psychologists, biomedical engineers, physicists and medical physicists. Both new and more advanced researchers alike will be able to discover new information distilled from the past decade of research to become well-versed in rs-fMRI-related topics. - Presents the first book to explain the latest methods, opportunities and challenges of Resting-state Functional MRI - Edited and authored by leading researchers in fMRI - Includes neuroscientific and clinical applications
Download or read book An Introduction to Resting State FMRI Functional Connectivity written by Janine Bijsterbosch and published by Oxford University Press. This book was released on 2017 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: For those new to the field of resting state fMRI, the large variety of approaches to functional connectivity analysis is highly confusing. This primer provides an introduction to the concepts and analysis decisions that need to be made at every step of the processing pipeline, starting from data acquisition through to interpretation of findings.
Download or read book Machine Learning in Medical Imaging written by Mingxia Liu and published by Springer Nature. This book was released on 2020-10-02 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 11th International Workshop on Machine Learning in Medical Imaging, MLMI 2020, held in conjunction with MICCAI 2020, in Lima, Peru, in October 2020. The conference was held virtually due to the COVID-19 pandemic. The 68 papers presented in this volume were carefully reviewed and selected from 101 submissions. They focus on major trends and challenges in the above-mentioned area, aiming to identify new-cutting-edge techniques and their uses in medical imaging. Topics dealt with are: deep learning, generative adversarial learning, ensemble learning, sparse learning, multi-task learning, multi-view learning, manifold learning, and reinforcement learning, with their applications to medical image analysis, computer-aided detection and diagnosis, multi-modality fusion, image reconstruction, image retrieval, cellular image analysis, molecular imaging, digital pathology, etc.
Download or read book Population Based Spatio temporal Probabilistic Modelling of FMRI Data written by Nahed Alowadi and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-dimensional functional magnetic resonance imaging (fMRI) data is characterized by complex spatial and temporal patterns related to neural activation. Mixture based Bayesian spatio-temporal modelling is able to extract spatiotemporal components representing distinct haemodyamic response and activation patterns. A recent development of such approach to fMRI data analysis is so-called spatially regularized mixture model of hidden process models (SMM-HPM). SMM-HPM can be used to reduce the four-dimensional fMRI data of a pre-determined region of interest (ROI) to a small number of spatio-temporal prototypes, sufficiently representing the spatio-temporal features of the underlying neural activation. Summary statistics derived from these features can be interpreted as quantification of (1) the spatial extent of sub-ROI activation patterns, (2) how fast the brain respond to external stimuli; and (3) the heterogeneity in single ROIs. This thesis aims to extend the single-subject SMM-HPM to a multi-subject SMM-HPM so that such features can be extracted at group-level, which would enable more robust conclusion to be drawn.
Download or read book Neuroscience in the 21st Century written by Donald W. Pfaff and published by Springer. This book was released on 2016-10-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.
Download or read book Functional MRI written by Ramachandran Ramani and published by Oxford University Press. This book was released on 2019-01-23 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional MRI: Basic Principles and Emerging Clinical Applications provides an overview of the basic principles of fMRI for clinicians with minimal knowledge of the imaging technique and its research potential and clinical applications. The text is divided into two parts, with Section I covering the primary signal measured in fMRI (BOLD), the correlation between neuronal activity and the BOLD signal, and how the data is analyzed and interpreted in fMRI. Section II explores applications of fMRI in cognitive neuroscience and common psychiatric disorders, surgical planning in neurosurgery, anesthesia and the intensive care unit, and more. Timely and highly accessible, this book is a valuable resource for researchers and clinicians interested in understanding what fMRI is, how it works, and its applications.
Download or read book Sleep and Anesthesia written by Axel Hutt and published by Springer Science & Business Media. This book was released on 2011-07-12 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sleep and anesthesia resemble in many ways at a first glance. The most prominent common feature of course is the loss of consciousness, i.e. the loss of awareness of external stimuli. However a closer look at the loss of consciousness reveals already a difference between sleep and anesthesia: anesthesia is induced by an anesthetic drug whereas we may fall asleep without external cause. Other questions may arise about the difference of the two effects: do we dream during surgery under anesthesia, do we feel pain during sleep? Essentially, we may ask: what is common and what are the differences between sleep and anesthesia? To answer these questions, we may take a look at the neural origin of both effects and the involved physiological pathways. In which way do they resemble? Moreover, we ask what are the detailed features of normal sleep and general anesthesia as applied during surgery and which features exist in both phenomena? If yes in which way? To receive answers to these questions, it is necessary to consider several experimental techniques that reveal underlying neural mechanisms of sleep and anesthesia. Moreover, theoretical models of neural activity may model both phenomena and comes up with predictions or even theories on the underlying mechanisms. Such models may attack several different description levels, from the microscopic level of single neurons to the macroscopic level of neural populations. Such models may give deeper insight into the phenomena if their assumptions are based on experimental findings and their predictions can be compared to experimental results. This comparison step is essential for valuable theoretical models. The book is motivated by two successful workshops on anesthesia and sleep organized during the Computational Neuroscience Conferences in Toronto in 2007 and in Berlin 2009. It aims to cover all the previous aspects with a focus on the link to experimental findings. It elucidates important issues in theoretical models that at the same time reflect some current major research interests. Moreover it considers some diverse issues which are very important to get an overview of the fields. For instance, the book discusses not only neural activity in the brain but also the effects of general anesthesia on the cardio-vascular system and the spinal cord in the context of analgesia. In addition, it considers different experimental techniques on various spatial scales, such as fMRI and EEG-experiments on the macroscopic scale and single neuron and LFP-measurements on the microscopic scale. In total all book chapters reveal aspects of the neural correlates of sleep and anesthesia motivated by experimental data. This focus on the neural mechanism in the light of experimental data is the common feature of the topics and the chapters. In addition, the book aims to clarify the shared physiological mechanisms of both phenomena, but also reveal their physiological differences.
Download or read book Handbook of MRI Pulse Sequences written by Matt A. Bernstein and published by Elsevier. This book was released on 2004-09-21 with total page 1041 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging (MRI) is among the most important medical imaging techniques available today. There is an installed base of approximately 15,000 MRI scanners worldwide. Each of these scanners is capable of running many different "pulse sequences", which are governed by physics and engineering principles, and implemented by software programs that control the MRI hardware. To utilize an MRI scanner to the fullest extent, a conceptual understanding of its pulse sequences is crucial. Handbook of MRI Pulse Sequences offers a complete guide that can help the scientists, engineers, clinicians, and technologists in the field of MRI understand and better employ their scanner. - Explains pulse sequences, their components, and the associated image reconstruction methods commonly used in MRI - Provides self-contained sections for individual techniques - Can be used as a quick reference guide or as a resource for deeper study - Includes both non-mathematical and mathematical descriptions - Contains numerous figures, tables, references, and worked example problems
Download or read book Neurocognitive Development Disorders and Disabilities written by and published by Elsevier. This book was released on 2020-09-25 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is one volume of a two-volume work on neurocognitive development, focusing separately on normative and non-normative development. The disorders and disabilities volume focuses on disorders of intellectual abilities, language, learning memory as well as psychiatric developmental disorders. The developmental aspects of neurological diseases in children is also covered. Chapters discuss when and how these disorders develop, the genetics and neurophysiology of their operation, and their evaluation and assessment in clinical practice. Assessment, treatment, and long-term outcome are provided as well as advances in methods and tools for assessment. This book will serve as a comprehensive reference to researchers in cognitive development in neuroscience, psychology, and medicine, as well as to clinicians and allied health professionals focused on developmental disabilities (child neurologists, pediatric neuropsychologists, child psychiatrists, speech and language therapists, and occupational therapists.) - Summarizes research on neurocognitive developmental disorders and disabilities - Includes disorders of intellectual abilities, language, learning, memory, and more - Separately covers developmental aspects of neurological diseases in children - Features advances in methods and tools of assessment - Reviews patient care, rehabilitation, and long-term outcomes - Provides interdisciplinary information of use to both researchers and clinicians
