Download or read book Targeting of Drugs 3 written by Gregory Gregoriadis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a NATO ASI held in Cape Sounion Beach, Greece, June 24-July 5, 1991

Download or read book Targeting of Drugs 6 written by Gregory Gregoriadis and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a NATO ASI held in Cape Sounion Beach, Greece, June 24-July 5, 1997

Download or read book Targeting of Drugs 4 written by Gregory Gregoriadis and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NATO Advanced Studies Institute series "Targeting of Drugs" was originated in 1981. It is now a major international forum, held every two years in Cape Sounion, Greece, in which the present and the future of this important area of research in drug delivery is discussed in great depth. Previous ASIs of the series dealt with drug carriers of natural and synthetic origin, their interaction with the biological milieu, ways by which the latter influences such interaction, strategies by which milieu interference curtailing the function of drug carriers is circumvented and, more recently, with the application of drug carriers for the delivery of peptides and proteins. The present book contains the of the 7th NATO ASI "Targeting of Drugs: Advances in System Constructs", proceedings held in Cape Sounion during 24 June -5 July 1993. As the title implies, the book deals with a variety of approaches to carrier design or modification that contribute to optimal carrier function. to Mrs Concha Perring for her assistance with the We express our appreciation organization of the ASI. We thank Dr. G. Deliconstantinos who, as chairperson of the Local Committee, contributed to the success of the Institute. The ASI was held under the sponsorship of NATO Scientific Affairs Division and co-sponsored and generously financed by SmithKline Beecham Pharmaceuticals (King of Prussia). Financial assistance was also provided by Liposome Technology Inc. (Menlo Park), Vestar Inc. (San Dimas) and Zeneka (Macclesfield).

Download or read book Targeting of Drugs written by Gregory Gregoriadis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Successful drug use in biology and medicine is often prejudiced by the failure of drugs that are otherwise active in vitro to act as efficiently in vivo. This is because in the living animal drugs must, as a rule, bypass or traverse organs, membranes, cells and molecules that stand between the site of administration and the site of action. In practice, however, drugs can be toxic to normal tissues, have limited or no access to the target and be prematurely excreted or inactivated. There is now growing optimism that such problems may be resolved by the use of carrier systems that will not only protect the non-target environment from the drugs they carry but also deliver them to where they are needed or facilitate their release there. Carrier systems presently under investigation include antibodies, glycoproteins, cells, reconstituted viruses and liposomes. Recent advances in the chemistry of cell receptor and receptor-recognising molecules, llnmunology, and natural and artificial membranes have revealed a multitude of ways in which such carrier systems can be modified or improved upon.

Download or read book Receptor Mediated Targeting of Drugs written by G. Gregoriadis and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional attempts to control cell behaviour and function are often marred by the toxicity of the drugs used, their premature waste or inactivation or by their inability to interact with or reach target sites efficiently. New trends in pharmacology empha size the development of methods for the optimization of drug action, for instance by the delivery of drugs, enzymes, hormones, antigens, genetic material, ets. through carrier systems selectively to re levant cellular and subcellular sites. A wide assortment of carriers was discussed in the first NATO Advanced Studies Institute (ASI) "Targeting of Drugs," the proceedings of which were published by Plenum Press in 1982 (eds., G. Gregoriadis, J. Senior and A. Trouet). This book, containing the proceedings of the 2nd NATO ASI "Receptor-Mediated Targeting of Drugs" held again at Cape Sounion, Greece during 20 June-l July 1983, deals with drug delivery through systems possessing ligands which can recognize and interact with receptors on the target's surface. Receptor-recognizing carriers that have recently given promise of realistic expectations in targeting include monoclonal antibodies, certain proteins that home to specific cells in the body and liposomes either as such (when they can trigger specific reactions in the reticuloendothelial system) or in association with targeting macromolecules. Each of these are discussed extensively by leading authorities, in terms of applications in biology and medicine and related methodologies.

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Download or read book Targeting of Drugs 2 written by Gregory Gregoriadis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1989

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Download or read book Targeting of Drugs 5 written by Gregory Gregoriadis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1995

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Download or read book Stealth Liposomes written by Danilo D. Lasic and published by CRC Press. This book was released on 2018-05-04 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines stealth liposomes from a multidisciplinary approach, which includes theoretical polymer physics, organic synthesis, colloid science, and biology. Discussions include theory, chemistry, biochemistry, pharmacology, preclinical studies in model systems, and medical applications in humans.