Download or read book Targeted Therapies in Lung Cancer Management Strategies for Nurses and Practitioners written by Marianne Davies and published by Springer. This book was released on 2019-07-16 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to educate nurses and advanced practice providers (APP’s) about known mutations, availability of targeted therapy and the management of patients with non-small cell lung cancer (NSCLC). It will educate nurses and practitioners about the scope of therapy to assure safe and effective lung cancer treatment. In this era of personalized medicine, nurses and APP’s are responsible for guiding patients from diagnosis through treatment. This starts with the identification of patients that can benefit from these therapies, the key role of biopsy acquisition (ie. what to test, when and how often) and treatment selection based on the mutation identified. Readers will learn about the mechanisms of action, administration, potential adverse side effects and unique management strategies for these targeted agents. Lung cancer continues to be the leading cause of cancer death in the United States and worldwide. Recent advances in the identification of specific oncogenic mutations that drive cancer development, growth and metastasis have led to major paradigm shifts in lung cancer treatment. Sophisticated methods are required to identify specific mutations at the time of diagnosis. This book explains how molecularly targeted therapies have been developed that target these drivers. To date, several tyrosine kinase inhibitors have been approved to target the epidermal growth factor receptor (EGFR), EML4-ALK ,ROS1 and BRAF. Most recently, immune checkpoint inhibitors have been approved with some indication that efficacy may be enhanced for patients who overexpress PD-L1. While some driver mutations have been identified, there is ongoing investigation into additional mutations. In the case of driver mutations, lung cancers will develop resistance to therapy. This book provides nurses and APP’s with the mechanisms of resistance that have been identified such as T790 mutation and many others in the EGFR mutation, and shows how the next level of drug development is focused on identifying mechanisms of resistance and development of new agents that overcome these mutations. With this book in hand, nurses and practitioners will be able to navigate patients through this ever expanding field of lung cancer treatment.
Download or read book Guide to Targeted Therapies Treatment Resistance in Lung Cancer written by Federico Cappuzzo and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a concise and up-to-date review, which discusses the background, development and mechanisms of resistance, testing methods and technology, current and emerging therapies and resources that clinicians can provide to their patients. Busy healthcare professionals who want a quick review of treatment resistance in lung cancer as well as a summary of current therapies will benefit from this succinct guide.
Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Download or read book Perspectives in Lung Cancer written by Keyvan Moghissi and published by Bentham Science Publishers. This book was released on 2020-07-23 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Perspectives in Lung Cancer compiles basic and advanced topics on lung cancer pathology and treatment in a single volume. Chapters introduce the reader to chest and lung anatomy followed by the biology of lung cancer. Subsequent chapters delve into diagnostic methods for lung cancer while progressing into treatment options. The book culminates into an explanation of the concept of the Lung Cancer Centre, which is a representation of the editors’ vision for organizing a lung cancer treatment unit. Key features: *Organises key topics covering both standard and avante-garde topics related to lung cancer *All contributions are presented by experts in lung cancer treatment *Addresses basic biology of lung cancer *Provides information about 3D surgical planning, a relatively new concept in the field of thoracic surgery *Addresses the standard method of resection, VATS and Mini VATS *Covers the role of radiation and systemic anti-cancer therapies in lung cancer treatment *Provides a glimpse of modern methods such as image guided surgery and therapy, laser therapy, and photodynamic therapy *Covers the role of palliative care for lung cancer *Presents information about a visionary organization of a lung cancer unit and treatment centre. The combination of carefully organised chapters covering a wide array of topics makes this reference an essential reference for healthcare professionals interested in acquiring a broad perspective on lung cancer treatment with the goal of improving patient outcomes.
Download or read book Personalised Cancer Medicine written by Anne Kerr and published by . This book was released on 2021-02-23 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Combinational Therapy in Triple Negative Breast Cancer written by Manzoor Ahmad Mir and published by Academic Press. This book was released on 2022-04-28 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combinational Therapy in Triple Negative Breast Cancer discusses TNBC at the molecular level from a holistic approach, focusing on combinational strategies targeting various pathways involved in this specific cancer type. Using a monotherapy for the treatment of cancer, especially high-grade tumors like TNBC, is mostly worthless due to the inherent genetic instability of tumor cells to develop intrinsic and acquired resistance. Combination therapy presents more, or at least the same, effectiveness with lower doses of every single agent and decreases the likelihood of chemoresistance, making it essential to understand for multiple therapy options. The book is a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of combinational therapies to treat triple negative breast cancer. Presents up-to-date and cutting-edge knowledge of Triple negative breast cancer (TNBC) biology, clinical aspects and treatment options Discusses novel targets and pathways involved in TNBC Provides insights and approaches for future research on TNBC
Download or read book Delivering Affordable Cancer Care in the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2013-06-20 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rising health care costs are a central fiscal challenge confronting the United States. National spending on health care currently accounts for 18 percent of gross domestic product (GDP), but is anticipated to increase to 25 percent of GDP by 2037. The Bipartisan Policy Center argues that "this rapid growth in health expenditures creates an unsustainable burden on America's economy, with far-reaching consequences". These consequences include crowding out many national priorities, including investments in education, infrastructure, and research; stagnation of employee wages; and decreased international competitiveness.In spite of health care costs that far exceed those of other countries, health outcomes in the United States are not considerably better. With the goal of ensuring that patients have access to high-quality, affordable cancer care, the Institute of Medicine's (IOM's) National Cancer Policy Forum convened a public workshop, Delivering Affordable Cancer Care in the 21st Century, October 8-9, 2012, in Washington, DC. Delivering Affordable Cancer Care in the 21st Century summarizes the workshop.
Download or read book Medical Surgical Nursing E Book written by Donna D. Ignatavicius and published by Elsevier Health Sciences. This book was released on 2015-01-30 with total page 1735 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a unique collaborative care approach to adult health nursing, Medical-Surgical Nursing: Patient-Centered Collaborative Care, 8th Edition covers the essential knowledge you need to succeed at the RN level of practice. Easy-to-read content includes evidence-based treatment guidelines, an enhanced focus on QSEN competencies, and an emphasis on developing clinical judgment skills. This edition continues the book’s trendsetting tradition with increased LGBTQ content and a new Care of Transgender Patients chapter. Written by nursing education experts Donna Ignatavicius and M. Linda Workman, this bestselling text also features NCLEX® Exam-style challenge questions to prepare you for success on the NCLEX Exam. Cutting-edge coverage of the latest trends in nursing practice and nursing education prepares you not just for today’s nursing practice but also for tomorrow’s.
Download or read book Childhood Cancer and Functional Impacts Across the Care Continuum written by National Academies of Sciences Engineering and Medicine and published by . This book was released on 2021-09-09 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Download or read book Targeted Therapies in Cancer written by Manfred Dietel and published by Springer. This book was released on 2014-11-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: From its introduction, oncological chemotherapy has been encumbered by poor selectivity because antiproliferative drugs are often toxic not only to tumor cells but also to important populations of the body’s non-neoplastic cells. Modern targeted therapies interact with defined molecules present on cancer cells, adding increased selectivity to their toxic effects. This book presents an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.
Download or read book The Comprehensive Cancer Center written by Mahmoud Aljurf and published by Springer Nature. This book was released on 2021-10-28 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a valuable resource for hospitals, institutions, and health authorities worldwide in their plans to set up and develop comprehensive cancer care centers. The development and implementation of a comprehensive cancer program allows for a systematic approach to evidence-based strategies of prevention, early detection, diagnosis, treatment, and palliation. Comprehensive cancer programs also provide a nexus for the running of clinical trials and implementation of novel cancer therapies with the overall aim of optimizing comprehensive and holistic care of cancer patients and providing them with the best opportunity to improve quality of life and overall survival. This book's self-contained chapter format aims to reinforce the critical importance of comprehensive cancer care centers while providing a practical guide for the essential components needed to achieve them, such as operational considerations, guidelines for best clinical inpatient and outpatient care, and research and quality management structures. Intended to be wide-ranging and applicable at a global level for both high and low income countries, this book is also instructive for regions with limited resources. The Comprehensive Cancer Center: Development, Integration, and Implementation is an essential resource for oncology physicians including hematologists, medical oncologists, radiation oncologists, surgical oncologists, and oncology nurses as well as hospitals, health departments, university authorities, governments and legislators.
Download or read book Selected Health Conditions and Likelihood of Improvement with Treatment written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-07-12 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.
Download or read book Quality of Life and Side Effects Management in Lung Cancer Treatment written by Alex Molassiotis and published by Frontiers Media SA. This book was released on 2021-04-13 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Medical surgical Nursing written by Donna D. Ignatavicius and published by Elsevier Health Sciences. This book was released on 2013 with total page 1905 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a uniquely collaborative and reader-friendly approach, expert authors Donna D. Ignatavicius and M. Linda Workman cover all the latest trends, evidence-based treatment guidelines, and additional updated information needed for safe clinical practice in medical-surgical nursing. This seventh edition features an expanded emphasis on patient safety and NCLEX? Examination preparation, new ties to the QSEN priorities for patient safety, and a greater alignment with the language and focus of clinical practice. A new chapter on evidence-based practice and a wealth of effective online learning tools help solidify your mastery of medical-surgical nursing.
Download or read book Cardiothoracic Surgical Critical Care An Issue of Critical Care Nursing Clinics of North America written by Bryan Boling and published by Elsevier Health Sciences. This book was released on 2019-07-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In consultation with Consulting Editor, Dr. Jan Foster, Dr. Brian Boling has put together a state-of the-art issue of the Critical Care Nursing Clinics devoted to Cardiothoracic Surgical Critical Care. Clinical review articles are specifically devoted to the following: Fast Track Cardiac Surgery; Options for Minimally Invasive Valvular Surgery; Surgical Interventions for the Treatment of Advanced Heart Failure; Lung Transplantation; Surgical Treatment of Lung Cancer; Post-Operative Management of Tetralogy of Fallot; Advanced Hemodynamic Monitoring in Cardiothoracic Surgery; Vasoactive Infusions in Cardiothoracic Surgery; Common Post Cardiothoracic Surgery Arrhythmias; Pain Control in the Cardiothoracic Surgery Patient; Renal Complications of Cardiothoracic Surgery; The Role of ECMO in Post Cardiotomy Shock; Resuscitation of Patients Who Arrest After Cardiac Surgery; and End of Life Care in Cardiothoracic Surgery. Readers will come away with the latest information they need to improve improves of cardiothoracic surgical patients.
Download or read book Core Curriculum for Oncology Nursing written by Joanne Itano and published by Elsevier Health Sciences. This book was released on 2005-01-01 with total page 993 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published in collaboration with the ONS, this text is the definitive source for concepts and practices in oncology nursing and can be used for orientation of nurses to oncology, inservice and continuing education programs for practicing nurses, a basis for curriculum development in graduate programs, and as a review tool for certification. Based on the blueprint of the certification examination by the ONCC (Oncology Nursing Certification Corporation), the book is in outline format to help readers focus on the most important information. Instructor resources available; contact your sales representative for details. Covers the entire scope of the specialty ensuring comprehensive coverage Outline format helps the reader focus on the most important information Effective guide for teaching and learning for in-service, continuing education, and academic programs Powerful study tool for the ONCC certification exam Tables and figures illustrate complex concepts * Entirely revised, updated, and expanded to reflect the current state of oncology nursing practice. * Expanded pain management content. * New content on nonpharmacologic interventions (e.g. heat massage, imagery). * New content on alternative therapies.
Download or read book Putting Evidence Into Practice written by Linda H. Eaton and published by . This book was released on 2011 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supplement to "Putting Evidence into Practice: Improving Oncology Patient Outcomes" (Eaton and Tipton, 2009).
