Download or read book The Use of CRISPR cas9 ZFNs TALENs in Generating Site Specific Genome Alterations written by and published by Academic Press. This book was released on 2014-11-04 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic information at specific sites in the genomes of animal, plant and bacterial cells. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods in biomineralization science - Contains sections on such topics as genome editing, genome engineering, CRISPR, Cas9, TALEN and zinc finger nuclease

Download or read book The Use of CRISPR Cas9 ZFNs and TALENs in Generating Site specific Genome Alterations written by Jennifer A. Doudna and published by Academic Press. This book was released on 2014 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers recent research and methods development for changing the DNA sequence within the genomes of cells and organisms. Focusing on enzymes that generate double-strand breaks in DNA, the chapters describe use of molecular tools to introduce or delete genetic information at specific sites in the genomes of animal, plant and bacterial cells. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Contains sections on such topics as genome editing, genome engineering, CRISPR, Cas9, TALEN and zinc finger nuclease

Download or read book Principles of Cloning written by Jose Cibelli and published by Academic Press. This book was released on 2013-09-24 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Cloning, Second Edition is the fully revised edition of the authoritative book on the science of cloning. The book presents the basic biological mechanisms of how cloning works and progresses to discuss current and potential applications in basic biology, agriculture, biotechnology, and medicine. Beginning with the history and theory behind cloning, the book goes on to examine methods of micromanipulation, nuclear transfer, genetic modification, and pregnancy and neonatal care of cloned animals. The cloning of various species—including mice, sheep, cattle, and non-mammals—is considered as well. The Editors have been involved in a number of breakthroughs using cloning technique, including the first demonstration that cloning works in differentiated cells done by the Recipient of the 2012 Nobel Prize for Physiology or Medicine – Dr John Gurdon; the cloning of the first mammal from a somatic cell – Drs Keith Campbell and Ian Wilmut; the demonstration that cloning can reset the biological clock - Drs Michael West and Robert Lanza; the demonstration that a terminally differentiated cell can give rise to a whole new individual – Dr Rudolf Jaenisch and the cloning of the first transgenic bovine from a differentiated cell – Dr Jose Cibelli. The majority of the contributing authors are the principal investigators on each of the animal species cloned to date and are expertly qualified to present the state-of-the-art information in their respective areas. - First and most comprehensive book on animal cloning, 100% revised - Describes an in-depth analysis of current limitations of the technology and research areas to explore - Offers cloning applications on basic biology, agriculture, biotechnology, and medicine

Download or read book Targeted Genome Editing Using Site Specific Nucleases written by Takashi Yamamoto and published by Springer. This book was released on 2015-01-05 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as breakthrough technologies. Genome editing with engineered nucleases allows us to precisely change the target genome of living cells and is a powerful way to control functional genes. It is feasible in almost all organisms ranging from bacteria to plants and animals, as well as in cultured cells such as ES and iPS cells. Various genome modifications have proven successful, including gene knockout and knock-in experiments with targeting vectors and chromosomal editing. Genome editing technologies hold great promise for the future, for example in biomedical research, clinical medicine, and generation of crops and livestock with desirable traits. A wide range of readers will find this book interesting, and with its focus on applications in a variety of organisms and cells, the book will be valuable for life scientists in all fields.

Download or read book Crop Improvement written by Pankaj Kumar and published by CRC Press. This book was released on 2021-06-30 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crop Improvement: Biotechnological Advances – Biomedical Science The field of biotechnology is advancing at a fast pace. The availability of low-cost DNA/genome sequencing technologies has led to the discovery and functional characterization of myriad of genes imparting stress tolerance and quality traits. The ‘omics’ group of technologies including genomics, proteomics, transcriptomics and metabolomics has revolutionized the agricultural biotechnology sector. The Nobel Prize-winning technology, such as the genome editing technique, is being employed to edit various gene functions in plants aiding in crop improvement. This technology may be adopted very quickly by consumers compared with the transgenic technique because the genome-edited plants have no adverse effects on the genome of the plant itself and on the environment and related species/non-target organisms. In this book, authors have attempted to compile the latest techniques of agricultural biotechnology and their applications in crop improvement. Certain chapters have been dedicated to describe the use of nanotechnology, a fast emerging new technique in the agriculture sector. Features Development, potential and safety issues in biotechnology Advances in genomics, proteomics and transcriptomics in agriculture Protein bioinformatics and its applications Genetically modified (GM) technology and its implications Genome editing in crop improvement Marker-assisted selection (MAS) in crop improvement Mutation breeding Cryobiotechnology Nanotechnology and biosensors This book includes real-world examples and applications making it accessible to a broader interdisciplinary readership. We hope that it will serve as a reference book for researchers engaged in molecular biology and biotechnology and will act as a ready reckoner for postgraduate (PG) students in the biotechnology discipline.

Download or read book New Urbanism and American Planning written by Emily Talen and published by Routledge. This book was released on 2005-11-16 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surveying four approaches to city-making, the author here gives an assessment of the development of American urbanism, highlighting recurrent themes and how these interact, merge and conflict.

Download or read book Recent Advances in Stem Cells written by Essam M. Abdelalim and published by Springer. This book was released on 2016-09-14 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores recent advances in the use of pluripotent stem cells (PSCs) and adult stem cells (ASCs) in basic and clinical applications. The chapters discuss use of PSCs for drug screening, genome editing, modeling of kidney, motor neuron diseases, and diabetes as well as their application in cancer; ASCs are discussed in the contexts of banking of umbilical cord stem cells, use of multipotential stromal cells (MSCs) for bone repair, cellular interactions during fracture repair stages, and therapeutic applications of neural crest stem cells and lung stem cells. The text is organized by sections dealing with PSCs and ASCs specifically, presenting the reader with a comprehensive examination of both these forms of stem cells. Expertly authored and drawing from a wealth of international perspectives, Recent Advances in Stem Cells: From Basic Research to Clinical Applications presents a succinct yet detailed review of cutting-edge research in this rapidly expanding field. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is essential reading for academics, researchers, and clinicians in the fields of cell biology, genetics, nephrology, osteology, oncology, and pulmonology.

Download or read book Color Harmony and Pigments written by Hilaire Hiler and published by . This book was released on 1942 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Genome Engineering for Crop Improvement written by Santosh Kumar Upadhyay and published by John Wiley & Sons. This book was released on 2021-01-05 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, significant advancements have been made in the management of nutritional deficiency using genome engineering—enriching the nutritional properties of agricultural and horticultural crop plants such as wheat, rice, potatoes, grapes, and bananas. To meet the demands of the rapidly growing world population, researchers are developing a range of new genome engineering tools and strategies, from increasing the nutraceuticals in cereals and fruits, to decreasing the anti-nutrients in crop plants to improve the bioavailability of minerals and vitamins. Genome Engineering for Crop Improvement provides an up-to-date view of the use of genome editing for crop bio-fortification, improved bioavailability of minerals and nutrients, and enhanced hypo-allergenicity and hypo-immunogenicity. This volume examines a diversity of important topics including mineral and nutrient localization, metabolic engineering of carotenoids and flavonoids, genome engineering of zero calorie potatoes and allergen-free grains, engineering for stress resistance in crop plants, and more. Helping readers deepen their knowledge of the application of genome engineering in crop improvement, this book: Presents genetic engineering methods for developing edible oil crops, mineral translocation in grains, increased flavonoids in tomatoes, and cereals with enriched iron bioavailability Describes current genome engineering methods and the distribution of nutritional and mineral composition in important crop plants Offers perspectives on emerging technologies and the future of genome engineering in agriculture Genome Engineering for Crop Improvement is an essential resource for academics, scientists, researchers, agriculturalists, and students of plant molecular biology, system biology, plant biotechnology, and functional genomics.

Download or read book Next Generation Plant Breeding Approaches for Stress Resilience in Cereal Crops written by Mallana Gowdra Mallikarjuna and published by Springer Nature. This book was released on 2022-09-15 with total page 507 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited book highlights the gravity and efficacy of next-generation breeding tools for the enhancement of stress-resilience in cereals, especially in the context of climate change, pests, diseases, and abiotic stresses. The content of the book helps in understanding the application of emerging genetic concepts and neoteric genomic approaches in cereal breeding. It collates all the latest information about enhancing the stress resilience in cereal crops for overcoming food security issues. Cereals have predominantly been used as a staple food since time immemorial and contribute more than 50% of the caloric requirement of the global population. However, in cereals, the yield losses due to various stresses are very high, considering the crop growth stage and stress sensitivity. Therefore, to feed and nourish the generations in the era of climate change, it is imperative to develop stress-resilient cereal cultivars. This book explores newly developed next-generation breeding tools, viz., genome-wide association studies, genomic prediction, genome editing, and accelerated generation advancement methodologies, which revealed promising outcomes by enhancing the stress resilience in cereals with yield potential. This book is useful for postgraduate students specializing in plant breeding, plant stress physiology, plant genomics, agriculture, and agronomy. It is of immense value to scientific community involved in teaching, research, and extension activities related to cereal cultivation.

Download or read book Enzymology at the Membrane Interface Intramembrane Proteases written by and published by Academic Press. This book was released on 2017-01-05 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymology at the Membrane Interface: Intramembrane Proteases, Volume 584, the latest release in the Methods in Enzymology series, covers a subset of enzymes that work in the environment of the biological cell membrane. This field, called interfacial enzymology, involves a special series of experimental approaches for the isolation and study of these enzymes. - Covers a subset of enzymes that work in the environment of the biological cell membrane - Offers a series of experimental approaches for the isolation and study of enzymes

Download or read book Classical Exercises upon the Rules of the French Syntax with references to Holder s Chambaud s Grammar written by George SATIS and published by . This book was released on 1794 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Stem Cells and Regenerative Medicine written by J.-F. Stoltz and published by IOS Press. This book was released on 2019-09-04 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the world’s population ages, the problem of degenerative disease is increasing. At the same time, the demand for organ transplants to repair or replace damaged tissue continues to grow. Regenerative medicine is a branch of translational medicine which promotes the repair, regeneration, or construction of tissues and organs or improves or restores their function through tissue engineering, cell biology, molecular biology and other techniques. Stem cells are one of the most important types of cells used in regenerative medicine, and stem cell research is also one of the most active research areas in the field. This book presents 20 full papers from the 8th International Symposium China-Europe “Stem Cells and Regenerative Medicine”, held in Wuhan, China from 19-21 June 2018. At this symposium, researchers in the field of stem cells and regenerative medicine from China and France discussed research from a molecular point of view and pointed out the clinical applications of mesenchymal stem cells, as well as the construction and applications of new biomaterials, the biomechanics of bone tissue engineering, and cellular immunotherapy, among other subjects. Stem cell technology could soon make possible the repair or replacement of aging and damaged tissue, as well as providing a treatment for genetic defects and malignancies,and this book will be of value to all those with an interest in regenerative medicine.

Download or read book Consumer Product Safety Commission Reauthorization written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Commerce, Consumer Protection, and Competitiveness and published by . This book was released on 1988 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Apoptosis in Health and Disease Part B written by Rossen Donev and published by Academic Press. This book was released on 2021-06-02 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apoptosis in Health and Disease - Part B, Volume 126 in the Advances in Protein Chemistry and Structural Biology focuses on apoptotic responses in numerous conditions - from bacterial and parasite infections, to pathological states such as oxidative stress, pulmonary hypertension, and different cancer types, etc. In addition, the book provides therapeutic strategies for targeting apoptosis. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target the cell death process. Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. Vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases. - Integrates experimental and computational methods for studying apoptosis in health and different diseases - Includes strategies for identification of suitable therapeutic targets - Discusses the design of treatments targeting key points in the apoptotic cascade

Download or read book Issues in Biotechnology and Medical Technology Research and Application 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-05-01 with total page 1177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues in Biotechnology and Medical Technology Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Biotechnology. The editors have built Issues in Biotechnology and Medical Technology Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biotechnology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biotechnology and Medical Technology Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Functional Genomics and Biotechnology in Solanaceae and Cucurbitaceae Crops written by Hiroshi Ezura and published by Springer. This book was released on 2016-01-04 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume summarizes recent technological advances in the design and engineering of Solanaceae and Cucurbitaceae crops. It begins with contributions on the tomato and melon genome sequence, databases for Solanaceae and Cucurbitaceae research, DNA markers in the breeding of the two families, and mutant resources and TILLING platforms in tomato research. Subsequent chapters address the use of molecular techniques for the modification of important breeding traits, such as tomato fruit set, growth, ripening, and sugar accumulation, as well as disease and insect resistance in melons. The volume closes with chapters on genome editing using artificial nucleases as a future breeding tool, and on the development of an in silico crop design system. It offers a valuable resource for plant breeders, molecular biologists, and agronomists.