Download or read book T1 Mapping in Myocardial Disease written by Phillip C. Yang and published by Springer. This book was released on 2018-08-28 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details the advances in cardiac MRI that have enabled quantitative tissue characterization of the myocardium using myocardial and blood T1 measurements, which have enabled reliable detection of diffuse pathological processes in both the cardiomyocytes and the interstitial cells of the myocardium. Evaluation of the native myocardial and interstitial fibrosis, and measurement of the extracellular volume fraction has allowed an unprecedented opportunity to elucidate the pathology, diagnosis and prognosis of cardiovascular disease. T1-Mapping in Myocardial Disease: Principles and Applications reviews a wide spectrum of significant cardiovascular disease and provides relevant guidance for the clinical implementation of this innovative technique. The specific topics covered include principles of T1-mapping in cardiovascular disease and the role of T1-mapping in hypertensive heart disease and hypertrophic cardiomyopathy, cardiotoxicity from cancer treatment, cardiacfibrosis, left ventricular hypertrophy in aortic stenosis, peri-infarct injury in ischemic cardiomyopathy, and stem cell therapy. This comprehensive coverage of the utility of T1-mapping in cardiovascular diseases will greatly appeal to the entire cardiovascular medicine and imaging communities.
Download or read book Dilated Cardiomyopathy written by Gianfranco Sinagra and published by Springer. This book was released on 2019-05-17 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book presents a comprehensive overview of dilated cardiomyopathy, providing readers with practical guidelines for its clinical management. The first part of the book analyzes in detail the disease’s pathophysiology, its diagnostic work up as well as the prognostic stratification, and illustrates the role of genetics and gene-environment interaction. The second part presents current and future treatment options, highlighting the importance of long-term and individualized treatments and follow-up. Furthermore, it discusses open issues, such as the apparent healing phenomenon, the early prognosis of arrhythmic events or the use of genetic testing in clinical practice. Offering a multidisciplinary approach for optimizing the clinical management of DCM, this book is an invaluable aid not only for the clinical cardiologists, but for all physicians involved in the care of this challenging disease.
Download or read book Diseases of the Chest Breast Heart and Vessels 2019 2022 written by Juerg Hodler and published by Springer. This book was released on 2019-02-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology.
Download or read book Myocardial T1 Mapping Techniques for Quantification of Myocardial Fibrosis written by Xiaopeng Zhou and published by . This book was released on 2012 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identifying and quantifying diffuse myocardial fibrosis is important to provide insights into the relationship between myocardial fibrosis, diastolic and systolic dysfunction, as well as clinical outcomes. T1 mapping is a promising technique for noninvasively identifying diffuse myocardial fibrosis in heart failure. A quantitative T1 map provides sensitivity to the full range of T1 values and is advantageous over the traditional T1-weighted imaging by reducing the reliance on visual interpretation of the signal intensity in the myocardium. However, in-vivo myocardial T1 quantification is challenging because of cardiac and respiratory motion. During the past few years, a variety of T1 mapping techniques, including the modified Look Locker inversion recovery (MOLLI) sequence, have been developed and optimized to measure the myocardial T1 value. Importantly, there have been significant differences between the T1 values determined by various methods, and several aspects of T1 mapping are incompletely understood. The accuracy of T1 mapping is sensitive to several confounding factors, such as the types of T1 mapping acquisition sequence and individual physiologic parameters. It also remains unclear if myocardial T1 values are constant throughout the cardiac cycle or the cyclic variation from the error of the variable flip angle (VFA) technique. Lastly, it is necessary to validate these techniques against the endomyocardial biopsy. The work intends to validate several aspects of T1 mapping. Firstly, whether there is significant cyclic variation of myocardial T1 at 1.5T was assessed in healthy volunteers and patients without myocardial disease. Secondly, a fast 3D DFA technique with B1 correction was developed to measure T1 comparably with gold standard in a wide range of T1 values, which showed it is necessary to incorporate B1 correction at 3T. Thirdly, Look Locker and MOLLI were compared to evaluate their agreement and difference in 3 patient groups precontrast and postcontrast situations. Finally, the T1 mapping technique was applied in a group of patients with diffuse myocardial fibrosis eligible for myectomy surgery. Precontrast and postcontrast myocardial T1 values were assessed to identify and quantify myocardial fibrosis, with subsequent histological validation based on intraoperative biopsies. The extracelluar volume calculated from T1 values positively correlated with histological analysis, which can help to guide the decision-making regarding when to send patients for invasive surgery and follow changes of fibrosis in the myocardium over time with noninvasive assessment.
Download or read book Cardiovascular Magnetic Resonance Imaging written by Raymond Y. Kwong and published by Springer. This book was released on 2019-01-31 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The significantly updated second edition of this important work provides an up-to-date and comprehensive overview of cardiovascular magnetic resonance imaging (CMR), a rapidly evolving tool for diagnosis and intervention of cardiovascular disease. New and updated chapters focus on recent applications of CMR such as electrophysiological ablative treatment of arrhythmias, targeted molecular MRI, and T1 mapping methods. The book presents a state-of-the-art compilation of expert contributions to the field, each examining normal and pathologic anatomy of the cardiovascular system as assessed by magnetic resonance imaging. Functional techniques such as myocardial perfusion imaging and assessment of flow velocity are emphasized, along with the exciting areas of artherosclerosis plaque imaging and targeted MRI. This cutting-edge volume represents a multi-disciplinary approach to the field, with contributions from experts in cardiology, radiology, physics, engineering, physiology and biochemistry, and offers new directions in noninvasive imaging. The Second Edition of Cardiovascular Magnetic Resonance Imaging is an essential resource for cardiologists and radiologists striving to lead the way into the future of this important field.
Download or read book The EACVI Textbook of Cardiovascular Magnetic Resonance written by Victor Ferrari and published by Oxford University Press. This book was released on 2018-09-13 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly comprehensive and informed textbook has been prepared by the Cardiovascular Magnetic Resonance section of the European Society of Cardiology association on imaging, the EACVI. The EACVI Textbook of Cardiovascular Magnetic Resonance is the authority on the subject. The textbook is aligned with ESC Core Curriculum and EACVI Core Syllabus for CMR. It is a practical resource and provides a disease orientated outlook on the subject. Structured with thirteen clear and detailed sections, ranging from Physics to Methodology, and featuring specific sections on ischemic heart disease, myocardial disease, pericardial disease, and congenital heart disease and adult congenital heart disease, The EACVI Textbook of Cardiovascular Magnetic Resonance provides extensive knowledge across the entire subject area in CMR. Beautifully illustrated and physical principles enriched with schematic animations, the textbook is advanced further with key video content based on clinical cases. Written by leading experts in the field from across the world, the textbook aims to summarise the existing research and clinical evidence for the various CMR indications and provide an invaluable resource for cardiologists and radiologists across the board. The textbook is ideal for cardiologists and radiologists new to the field of Cardiovascular Magnetic Resonance, those preparing for ESC certification in CMR, and those established in the field wishing to gain a deep understanding of CMR. Online access to the digital version is included with purchase of the print book, with accompanying videos referenced within the text available on Oxford Medicine Online.
Download or read book Multimodality Imaging written by Qifa Zhou and published by . This book was released on 2020 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a state-of-the-art overview of the combined use of imaging modalities to obtain important functional and morphological information on intravascular disease and enhance disease detection. It discusses the integration of intravascular ultrasound (IVUS, intravascular optical coherence tomography (OCT), intravascular photoacoustic imaging (IVPA) and acoustic radiation force optical coherence elastography (ARF-OCE), and introduces the integration of multimodality imaging systems, such as IR and florescence. It includes the latest research advances and numerous imaging photos to offer readers insights into current intravascular applications. It is a valuable resource for students, scientists and physicians wanting to gain a deeper understanding of multimodality imaging tools.
Download or read book Multimodality Imaging Innovations In Adult Congenital Heart Disease written by Pastora Gallego and published by Springer Nature. This book was released on 2021-06-16 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on congenital heart disease (CHD) and emerging imaging technologies. It covers all clinically relevant aspects of the fascinating new cardiac imaging technologies, including a comprehensive explanation of their basic principles, practical aspects of novel clinical applications, and detailed descriptions of specific uses in the broad spectrum of clinically important adult CHD. Innovations and emerging technologies for diagnosis and therapeutics, evaluation and treatment are continually evolving, and due to these advances in non-invasive diagnosis, there has been a significant improvement in the survival rates for CHD patient. Novel approaches to trans-catheter interventions and advances in echocardiography, MRI and CT imaging are being developed and incorporated into routine clinical practice, while emerging three-dimensional printing technologies are fundamentally affecting patient care, research, trainee education, and interactions between multidisciplinary teams, patients, and caregivers. In addition, translational technologies on the horizon promise to take this nascent field even further. Exploring the applicability of these emerging technologies in improving our understanding of complex congenital cardiac defect anatomy and physiology will provide new treatment options for this unique population. Written by experts in the field who are also involved in patient care, this book discusses the practical application of innovations in advanced multimodality imaging in the daily clinical routine and offers tips and tricks for beginners.
Download or read book Myocardial Tissue Characterization Using Magnetic Resonance Imaging written by Sofia Kvernby and published by Linköping University Electronic Press. This book was released on 2019-02-18 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: In cardiovascular disease, which is the most common cause of death in the world, early diagnosis is crucial for disease outcome. Diagnosis of cardiovascular disease can be challenging, though. Quantification of myocardial T1 and T2 relaxation times with MRI has demonstrated to be a promising method for characterizing myocardial tissue, but long measurement times have hampered clinical use. The overall aim of this doctoral thesis was to develop, validate and, in patient studies, evaluate a very fast three-dimensional method for simultaneous quantification of myocardial T1 and T2 relaxation times with whole coverage of the left ventricle. The 3D-QALAS method is presented in Paper I of this thesis. It is a method that simultaneous measures both T1 and T2 relaxation times in a three-dimensional volume of the heart. The method requires 15 heartbeats, to produce 13 short-axis slices of the left ventricle with voxelwise information of both T1 and T2 relaxation times. The 3D-QALAS method was validated in phantoms and in 10 healthy volunteers by comparing the method with reference methods and demonstrated good accuracy and robustness both in-vitro and in-vivo. In Paper II, the 3D-QALAS method was carefully validated in-vivo by investigating accuracy and precision in 10 healthy volunteers, while the clinical feasibility of the method was investigated in 23 patients with various cardiac pathologies. Repeated independent and dependent scans together with the intra-scan repeatability, demonstrated all a very good precision for the 3D-QALAS method in healthy volunteers. In Paper III and IV, the 3D-QALAS method was applied and evaluated in patient cohorts where the heart muscle alters over time. In Paper III, patients with severe aortic stenosis underwent MRI examinations with 3D-QALAS before, 3 months after and 12 months after aortic valve surgery. Changes in T1 and T2 were observed, which might be used as markers of myocardial changes with respect to edema and fibrosis, which may develop due to increased workload over a long period of time. In study IV, 3D-QALAS was used to investigate 10 breast cancer patients treated with radiation therapy prior to treatment, 2-3 weeks into treatment, and one and 6 months after completion of treatment, to investigate any changes in T1 and T2 and further if they can be correlated to unwanted irradiation of the heart during radiation therapy.
Download or read book Cardiovascular Computed Tomography written by James Stirrup and published by Oxford University Press, USA. This book was released on 2020-01-02 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have seen a marked increase in cardiovascular computed tomography (CT) imaging, with the technique now integrated into many imaging guidelines, such as those published by ESC and NICE. Rapid clinical and technological progress has created a need for guidance on the practical aspects of CT image acquisition, analysis and interpretation. The Oxford Specialist Handbook of Cardiovascular CT, now revised for the second edition by practising international experts with many years of hands-on experience, is designed to fulfil this need. The Handbook is a practical guide on performing, analysing and interpreting cardiovascular CT scans, covering all aspects from patient safety to optimal image acquisition to differential diagnoses of tricky images. It takes an international approach to both accreditation and certification, highlighting British, European, and American examinations and courses. The format is designed to be accessible and is laid out in easy to navigate sections. It is meant as a quick-reference guide, to live near the CT scanner, workstation, or on the office shelf. The Handbook is aimed at all cardiovascular CT users (Cardiologists, Radiologists and Radiographers), particularly those new to cardiovascular CT, although even the advanced user should find useful tips and tricks within.
Download or read book Diagnosis and Management of Hypertrophic Cardiomyopathy written by Barry J. Maron and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnosis and Management of Hypertrophic Cardiomyopathy is aunique, multi-authored compendium of information regarding thecomplexities of clinical and genetic diagnosis, natural history,and management of hypertrophic cardiomyopathy (HCM)—the mostcommon and important of the genetic cardiovasculardiseases—as well as related issues impacting the health oftrained athletes. Edited by Dr. Barry J. Maron, a world authority on HCM, and withmajor contributions from all of the international experts in thisfield, this book provides a single comprehensive source ofinformation concerning HCM. Recent advances in the field arediscussed, including the importance of left ventricular outflowtract obstruction, the use of implantable defibrillators for theprevention of sudden death in young people, definition of thegenetic basis for HCM and its role in clinical diagnosis and riskstratification, the development of more precise strategies forassessing the level of risk for sudden death among all patientswith HCM, and the evolution of invasive interventions for heartfailure symptoms, such as surgical management and its alternatives(alcohol septal ablation and dual-chamber pacing). Key Features: Contributions from all experts in the field,representing diverse viewpoints regarding this heterogeneousdisease and related issues in athletes Information to dispel misunderstandings regarding issuesassociated with HCM and cardiovascular disease in athletes The only comprehensive source of information available on thetopic
Download or read book Genetic Cardiomyopathies written by Gianfranco Sinagra and published by Springer Science & Business Media. This book was released on 2012-12-09 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decade, genetics has been emerging as a primary issue in the diagnosis and management of cardiomyopathies. This book is intended to be a state-of-the-art monograph on these diseases, describing their genetic causes, defining the molecular basis and presenting extensive descriptions of genotype–phenotype correlations. Other chapters are focused on the role of clinical observation, on ECG and echocardiography. With its highlight on the most recent discoveries in the field of molecular genetics as well as on the correct clinical approach to patients with heart muscle disease, the book is aimed at physicians and clinical cardiologists with a particular interest in myocardial diseases and in their genetic causes.
Download or read book Interstitial Fibrosis in Heart Failure written by Francisco Villarreal and published by Springer Science & Business Media. This book was released on 2005 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interstitial Fibrosis in Heart Failure, edited by Francisco J. Villarreal, M.D., Ph.D., provides a timely and integrative review of the basics of cardiac extracellular matrix structure. Topics covered include how cardiac remodeling influences its disposition, abundance and function; possible non-invasive techniques for diagnosis; and potential drug-based or molecular therapeutic strategies that may interrupt or even reverse the course of the development of cardiac fibrosis. This resource for both clinicians and scientists aims to cover state-of-the-art findings relevant to cellular and molecular processes underlying cardiac fibrosis including basic elements of structure, function, diagnosis and treatment.
Download or read book Cardiac Magnetic Resonance T1 Mapping in Cardiomyopathies written by Christian R. Hamilton-Craig and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac magnetic resonance (CMR) imaging has been widely used to assess myocardial perfusion and scar and is the noninvasive reference standard for identification of focal myocardial fibrosis. However, the late gadolinium enhancement (LGE) technique is limited in its accuracy for absolute quantification and assessment of diffuse myocardial fibrosis by technical and pathophysiological features. CMR relaxometry, incorporating T1 mapping, has emerged as an accurate, reproducible, highly sensitive, and quantitative technique for the assessment of diffuse myocardial fibrosis in a number of disease states. We comprehensively review the physics behind CMR relaxometry, the evidence base, and the clinical applications of this emerging technique.
Download or read book Man Machine Interactions 2 written by Tadeusz Czachorski and published by Springer Science & Business Media. This book was released on 2011-08-30 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Man-machine interaction is the interdisciplinary field, focused on a human and a machine in conjunction. It is the intersection of computer science, behavioural sciences, social psychology, ergonomics, security. It encompasses study, design, implementation, and evaluation of small- and large-scale, interacting, computing, hardware and software systems dedicated for human use. Man-machine interaction builds on supportive knowledge from both sides, the machine side providing techniques, methods and technologies relevant for computer graphics, visualisation, programming environments, the human side bringing elements of communication theory, linguistics, social sciences, models of behaviour. The discipline aims to improve ways in which machines and their users interact, making hardware and software systems better adapted to user's needs, more usable, more receptive, and optimised for desired properties. This monograph is the second edition in the series, providing the reader with a selection of high-quality papers dedicated to current progress, new developments and research trends in man-machine interactions area. In particular, the topical subdivisions of this volume include human-computer interfaces, robot control and navigation systems, bio-data analysis and mining, pattern recognition for medical applications, sound, text and image processing, design and decision support, rough and fuzzy systems, crisp and fuzzy clustering, prediction and regression, algorithms and optimisation, and data management systems.
Download or read book Cardiac Mapping written by Mohammad Shenasa and published by John Wiley & Sons. This book was released on 2019-04-04 with total page 1304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The expanded guide to cardiac mapping The effective diagnosis and treatment of heart disease may vitally depend upon accurate and detailed cardiac mapping. However, in an era of rapid technological advancement, medical professionals can encounter difficulties maintaining an up-to-date knowledge of current methods. This fifth edition of the much-admired Cardiac Mapping is, therefore, essential, offering a level of cutting-edge insight that is unmatched in its scope and depth. Featuring contributions from a global team of electrophysiologists, the book builds upon previous editions' comprehensive explanations of the mapping, imaging, and ablation of the heart. Nearly 100 chapters provide fascinating accounts of topics ranging from the mapping of supraventricular and ventriculararrhythmias, to compelling extrapolations of how the field might develop in the years to come. In this text, readers will find: Full coverage of all aspects of cardiac mapping, and imaging Explorations of mapping in experimental models of arrhythmias Examples of new catheter-based techniques Access to a companion website featuring additional content and illustrative video clips Cardiac Mapping is an indispensable resource for scientists, clinical electrophysiologists, cardiologists, and all physicians who care for patients with cardiac arrhythmias.
Download or read book Free Breathing Non ECG T1 Mapping in the Heart written by Jaime Shaw and published by . This book was released on 2017 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular diseases are the leading cause of death in the United States, translating to a high cost burden on the healthcare system. Noninvasive imaging can play a significant role in the diagnosis and triaging of cardiovascular diseases. Cardiac MRI is a noninvasive imaging technique becoming more prevalent due to its advantage of providing excellent soft-tissue contrast and high spatial resolution without the use of ionizing radiation; however, major challenges exist including respiratory and cardiac motion. One emerging application of cardiac MRI is myocardial tissue characterization using quantitative mapping techniques. Current mapping techniques rely on electrocardiogram (ECG)-gating which assumes normal sinus rhythm, as well as breath-holds or respiratory monitoring which preclude some patients from scans or prolong scan time. Quantification of spin-lattice relaxation times (or T1 mapping) of the myocardium has been shown to enable detection of diffuse myocardial fibrosis, a key feature in the progression of many cardiac diseases. The main focus of this dissertation is to remove the limitations of ECGs and respiratory monitoring from cardiac MRI to enable free-breathing, non-ECG T1 mapping. The first objective of this dissertation was to develop a two-dimensional, free-breathing, non-ECG, continuous T1 mapping technique and validate it in imaging phantoms using a gold-standard technique. We compare the T1 and extracellular volume (ECV) values to a conventional breath-hold, ECG-gated, T1 mapping technique in healthy subjects. The repeatability and accuracy of the technique were assessed for different length scans. The second objective was to demonstrate the feasibility of quantifying T1 values throughout the cardiac cycle and to assess cardiac function simultaneously with a method free of ECG and prospective respiratory monitoring. The third objective of this dissertation was to develop a three-dimensional free-breathing, non-ECG T1 mapping technique capable of providing T1 and ECV maps with full coverage of the left ventricle. This dissertation lays the groundwork for quantitative cardiac MRI with no reliance on prospective respiratory monitoring or ECGs. The removal of these limitations makes cardiac MRI accessible to all types of patients and provides a comfortable scan environment with no breath-holding. This dissertation represents a move toward a "push-button" cardiac MRI paradigm, wherein one scan with minimal setup can provide information comparable to a complex standard-of-care cardiac MRI scan.
