Download or read book Dynamical System Theory in Biology Stability theory and its applications written by Robert Rosen and published by John Wiley & Sons. This book was released on 1970 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mathematical Systems Theory in Biology Communications Computation and Finance written by Joachim Rosenthal and published by Springer Science & Business Media. This book was released on 2003-09-02 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains survey and research articles by some of the leading researchers in mathematical systems theory - a vibrant research area in its own right. Many authors have taken special care that their articles are self-contained and accessible also to non-specialists.
Download or read book Control Theory and Systems Biology written by Pablo A. Iglesias and published by MIT Press. This book was released on 2010 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: A survey of how engineering techniques from control and systems theory can be used to help biologists understand the behavior of cellular systems.
Download or read book Philosophy of Systems Biology written by Sara Green and published by Springer. This book was released on 2016-12-15 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence of systems biology raises many fascinating questions: What does it mean to take a systems approach to problems in biology? To what extent is the use of mathematical and computational modelling changing the life sciences? How does the availability of big data influence research practices? What are the major challenges for biomedical research in the years to come? This book addresses such questions of relevance not only to philosophers and biologists but also to readers interested in the broader implications of systems biology for science and society. The book features reflections and original work by experts from across the disciplines including systems biologists, philosophers, and interdisciplinary scholars investigating the social and educational aspects of systems biology. In response to the same set of questions, the experts develop and defend their personal perspectives on the distinctive character of systems biology and the challenges that lie ahead. Readers are invited to engage with different views on the questions addressed, and may explore numerous themes relating to the philosophy of systems biology. This edited work will appeal to scholars and all levels, from undergraduates to researchers, and to those interested in a variety of scholarly approaches such as systems biology, mathematical and computational modelling, cell and molecular biology, genomics, systems theory, and of course, philosophy of biology.
Download or read book Systems Theory written by Francisco Miranda and published by Nova Science Publishers. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Theory is a transdisciplinary field that involves complex combinations of different research fields with the purpose to explain the observed natural phenomena in the world around us. This field results in the appearance of the General System Theory. The aim of the present book is to present some of what is being done, in the 21st century, in different fields that comprise the Systems Theory. In the several chapters of this book developments of this theory are presented with the aim to solve different problems of systems. Different areas are covered, from biology and psychology to electronics, information sciences and management. The authors present their research in the study of the synthetic and systems biology, systems theory of bipolar disorder, unifying principles of science through physical activities, control of linear and non-linear systems, class of superquadratic Hamiltonian systems, systems with propagation, wireless sensor networks, information systems, and service operations management. This book is a tool composed by several results in the systems theory of several research fields with important application in the resolution of the problem of understanding our world.
Download or read book Nanostructures in Biological Systems written by Aleš Iglič and published by CRC Press. This book was released on 2015-06-17 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a survey on the theoretical as well as experimental results on nanostructures in biological systems. It shows how a unifying approach starting from single-particle energy, deriving free energy of the system and determining the equilibrium by minimizing the free energy, can be applied to describe electrical and elastic phenomena. It hel
Download or read book Foundations of Complex system Theories written by Sunny Y. Auyang and published by Cambridge University Press. This book was released on 1998 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analyzes approaches to the study of complexity in the physical, biological, and social sciences.
Download or read book Systems Biology of Cell Signaling written by James Ferrell and published by Garland Science. This book was released on 2021-09-28 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: How can we understand the complexity of genes, RNAs, and proteins and the associated regulatory networks? One approach is to look for recurring types of dynamical behavior. Mathematical models prove to be useful, especially models coming from theories of biochemical reactions such as ordinary differential equation models. Clever, careful experiments test these models and their basis in specific theories. This textbook aims to provide advanced students with the tools and insights needed to carry out studies of signal transduction drawing on modeling, theory, and experimentation. Early chapters summarize the basic building blocks of signaling systems: binding/dissociation, synthesis/destruction, and activation/inactivation. Subsequent chapters introduce various basic circuit devices: amplifiers, stabilizers, pulse generators, switches, stochastic spike generators, and oscillators. All chapters consistently use approaches and concepts from chemical kinetics and nonlinear dynamics, including rate-balance analysis, phase plane analysis, nullclines, linear stability analysis, stable nodes, saddles, unstable nodes, stable and unstable spirals, and bifurcations. This textbook seeks to provide quantitatively inclined biologists and biologically inclined physicists with the tools and insights needed to apply modeling and theory to interesting biological processes. Key Features: Full-color illustration program with diagrams to help illuminate the concepts Enables the reader to apply modeling and theory to the biological processes Further Reading for each chapter High-quality figures available for instructors to download
Download or read book Theoretical Biology and Complexity written by Robert Rosen and published by . This book was released on 1985 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theoretical Biology and Complexity: Three Essays on the Natural Philosophy of Complex Systems is made up of three short essays-each separately conceived and written, each with distinct thrusts and emphases, but nevertheless closely related in substance and spirit. All three spring from a common concern: to grasp and comprehend the material basis of living systems. The first essay is about the interaction between particles and the consequent observable manifestations. It casts the analysis of the measurement process into an elegant dualism relating modes of description, and explores the conseq ...
Download or read book An Introduction to Systems Biology written by Uri Alon and published by CRC Press. This book was released on 2006-07-07 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thorough and accessible, this book presents the design principles of biological systems, and highlights the recurring circuit elements that make up biological networks. It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.
Download or read book Systems Biology written by Bernhard Palsson and published by Cambridge University Press. This book was released on 2015-01-26 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive single-authored textbook on genome-scale models and the bottom-up approach to systems biology.
Download or read book Life An Introduction to Complex Systems Biology written by Kunihiko Kaneko and published by Springer. This book was released on 2006-09-14 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines life not from the reductionist point of view, but rather asks the questions: what are the universal properties of living systems, and how can one construct from there a phenomenological theory of life that leads naturally to complex processes such as reproductive cellular systems, evolution and differentiation? The presentation is relatively non-technical to appeal to a broad spectrum of students and researchers.
Download or read book The Dynamics of Biological Systems written by Arianna Bianchi and published by Springer Nature. This book was released on 2019-10-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents nine mini-courses from a summer school, Dynamics of Biological Systems, held at the University of Alberta in 2016, as part of the prestigious seminar series: Séminaire de Mathématiques Supérieures (SMS). It includes new and significant contributions in the field of Dynamical Systems and their applications in Biology, Ecology, and Medicine. The chapters of this book cover a wide range of mathematical methods and biological applications. They - explain the process of mathematical modelling of biological systems with many examples, - introduce advanced methods from dynamical systems theory, - present many examples of the use of mathematical modelling to gain biological insight - discuss innovative methods for the analysis of biological processes, - contain extensive lists of references, which allow interested readers to continue the research on their own. Integrating the theory of dynamical systems with biological modelling, the book will appeal to researchers and graduate students in Applied Mathematics and Life Sciences.
Download or read book Feedback Control in Systems Biology written by Carlo Cosentino and published by CRC Press. This book was released on 2011-10-17 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Like engineering systems, biological systems must also operate effectively in the presence of internal and external uncertainty—such as genetic mutations or temperature changes, for example. It is not surprising, then, that evolution has resulted in the widespread use of feedback, and research in systems biology over the past decade has shown that feedback control systems are widely found in biology. As an increasing number of researchers in the life sciences become interested in control-theoretic ideas such as feedback, stability, noise and disturbance attenuation, and robustness, there is a need for a text that explains feedback control as it applies to biological systems. Written by established researchers in both control engineering and systems biology, Feedback Control in Systems Biology explains how feedback control concepts can be applied to systems biology. Filling the need for a text on control theory for systems biologists, it provides an overview of relevant ideas and methods from control engineering and illustrates their application to the analysis of biological systems with case studies in cellular and molecular biology. Control Theory for Systems Biologists The book focuses on the fundamental concepts used to analyze the effects of feedback in biological control systems, rather than the control system design methods that form the core of most control textbooks. In addition, the authors do not assume that readers are familiar with control theory. They focus on "control applications" such as metabolic and gene-regulatory networks rather than aircraft, robots, or engines, and on mathematical models derived from classical reaction kinetics rather than classical mechanics. Another significant feature of the book is that it discusses nonlinear systems, an understanding of which is crucial for systems biologists because of the highly nonlinear nature of biological systems. The authors cover tools and techniques for the analysis of linear and nonlinear systems; negative and positive feedback; robustness analysis methods; techniques for the reverse-engineering of biological interaction networks; and the analysis of stochastic biological control systems. They also identify new research directions for control theory inspired by the dynamic characteristics of biological systems. A valuable reference for researchers, this text offers a sound starting point for scientists entering this fascinating and rapidly developing field.
Download or read book Fundamentals of Systems Biology written by Markus W. Covert and published by CRC Press. This book was released on 2017-10-19 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades biology has focused on decoding cellular processes one gene at a time, but many of the most pressing biological questions, as well as diseases such as cancer and heart disease, are related to complex systems involving the interaction of hundreds, or even thousands, of gene products and other factors. How do we begin to understand this complexity? Fundamentals of Systems Biology: From Synthetic Circuits to Whole-cell Models introduces students to methods they can use to tackle complex systems head-on, carefully walking them through studies that comprise the foundation and frontier of systems biology. The first section of the book focuses on bringing students quickly up to speed with a variety of modeling methods in the context of a synthetic biological circuit. This innovative approach builds intuition about the strengths and weaknesses of each method and becomes critical in the book’s second half, where much more complicated network models are addressed—including transcriptional, signaling, metabolic, and even integrated multi-network models. The approach makes the work much more accessible to novices (undergraduates, medical students, and biologists new to mathematical modeling) while still having much to offer experienced modelers--whether their interests are microbes, organs, whole organisms, diseases, synthetic biology, or just about any field that investigates living systems.
Download or read book Anticipatory Systems written by Robert Rosen and published by Elsevier. This book was released on 2013-10-22 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first detailed study of this most important class of systems which contain internal predictive models of themselves and/or of their environments and whose predictions are utilized for purposes of present control. This book develops the basic concept of a predictive model, and shows how it can be embedded into a system of feedforward control. Includes many examples and stresses analogies between wired-in anticipatory control and processes of learning and adaption, at both individual and social levels. Shows how the basic theory of such systems throws a new light both on analytic problems (understanding what is going on in an organism or a social system) and synthetic ones (developing forecasting methods for making individual or collective decisions).
Download or read book Systems Theory and Biology written by Mihajlo D. Mesarovic and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: By J OHN A. HRONES Provost, Case Institute 0/ Technology SYSTEMS have been the subject of man's study for many hundreds of years. Thus, the solar system has been the concern of the astronomer. The study of the allocation of material and human resources within the boundaries of an industrial firm or a government has been the concern of the economist. The subject of such studies have been widely known as economic systems. Medieal men have worked with the human body. Thus, man has attempted to deal with a complicated array of interconnected elements since the very earliest of recorded time. In his attcmpt to improve his understanding of physieal systems the need to concentrate on a specific kind of system, e.g., the solar system. the human body, became more imperative. However in recent years there has begun to grow and develop an increasing number of people who are working on thc development of general systems theory and analysis. Such a development is based upon the belief that certain view points, certain kinds of mathematics and technologieal procedures can be applied to a wide variety of important systems with considerable profit. The pres sures for the development of such a body of knowledge grew with the de velopment of a technologieal socicty.
