Download or read book Systems Biology and Computational Proteomics written by Trey Ideker and published by Springer Science & Business Media. This book was released on 2007-07-20 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications.
Download or read book Proteomics and Systems Biology written by and published by Academic Press. This book was released on 2021-07-30 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteomics and Systems Biology, Volume 127 in the Advances in Protein Chemistry and Structural Biology series, outlines current proteomic methodologies and discuss the challenges in future applications of systems biology in a number of biomedical/bioscience subjects. In last few decades, advances in genomics, proteomics, metabolomics, glycomics, venomics, etc., have produced vast large-scale datasets that need to be analyzed with a single main objective of understanding biological systems as a whole. Such understanding will allow us to predict and characterize the dynamic properties of biological systems. Integrates experimental and computational methods for understanding biological systems as a whole Contains timely chapters written by well-renowned authorities in their field Includes well supported content that is accompanied by a number of high-quality illustrations, figures and tables, hence it targets a wide audience of specialists, researchers and students
Download or read book Systems Biology and Computational Proteomics written by Trey Ideker and published by Springer. This book was released on 2009-09-02 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events: the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The papers cover various aspects of systems biology and explore the use of computational mass spectrometry in various proteomic applications.
Download or read book Introduction to Computational Proteomics written by Golan Yona and published by CRC Press. This book was released on 2010-12-09 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Computational Proteomics introduces the field of computational biology through a focused approach that tackles the different steps and problems involved with protein analysis, classification, and meta-organization. The book starts with the analysis of individual entities and works its way through the analysis of more complex entitie
Download or read book Transactions on Computational Systems Biology I written by Corrado Priami and published by Springer Science & Business Media. This book was released on 2005-03-30 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena. This first volume of the Transactions on Computational Systems Biology is made up of papers by members of the journal's Editorial Board to provide a representative and smart start-up to the new journal.
Download or read book Proteomics in Systems Biology written by Jennifer Geddes-McAlister and published by Springer Nature. This book was released on 2022-05-25 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book highlights the diverse techniques and applications of proteomics in an accessible, informative, and concise manner. The collection features sample preparation from distinct extraction, quantification, enrichment, modification, as well as interactome methodology for the in-depth exploration of biological systems, and the application of proteomics to clinical, infectious disease, and agricultural practices. Moreover, cutting-edge bioinformatics tools, encompassing machine learning and data integration strategies, are explored, as are techniques expanding beyond proteomics into the realm of metabolomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting known pitfalls. Comprehensive and practical, Proteomics in Systems Biology: Methods and Protocols emphasizes the importance of proteomics and demonstrates a plethora of approaches for investigating diverse biological entities from a systems perspective.
Download or read book Computational Proteomics Systems Biology Et Clinical Implications written by Martin Eisenacher and published by . This book was released on 2014 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Frontiers of Network Analysis in Systems Biology written by Avi Ma'ayan and published by Springer Science & Business Media. This book was released on 2012-06-25 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly developing field of systems biology is influencing many aspects of biological research and is expected to transform biomedicine. Some emerging offshoots and specialized branches in systems biology are receiving particular attention and are becoming highly active areas of research. This collection of invited reviews describes some of the latest cutting-edge experimental and computational advances in these emerging sub-fields of systems biology. In particular, this collection focuses on the study of mammalian embryonic stem cells; new technologies involving mass-spectrometry proteomics; single cell measurements; methods for modeling complex stochastic systems; network-based classification algorithms; and the revolutionary emerging field of systems pharmacology.
Download or read book Transactions on Computational Systems Biology X written by Corrado Priami and published by Springer. This book was released on 2010-06-27 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technology is taking us to a world where myriads of heavily networked devices interact with the physical world in multiple ways, and at many levels, from the globalInternetdowntomicroandnanodevices. Manyofthesedevicesarehighly mobile and autonomous and must adapt to the surrounding environment in a totally unsupervised way. A fundamental research challenge is the design of robust decentralized c- puting systemsthat arecapableofoperating in changing environmentsandwith noisy input, and yet exhibit the desired behavior and response time, under c- straints such as energy consumption, size, and processing power. These systems should be able to adapt and learn how to react to unforeseen scenarios as well as to display properties comparable to social entities. The observation of nature has brought us many great and unforeseen concepts. Biological systems are able to handle many of these challenges with an elegance and e?ciency far beyond currenthumanartifacts. Basedonthisobservation,bio-inspiredapproacheshave been proposed as a means of handling the complexity of such systems. The goal is to obtain methods to engineer technical systems, which are of a stability and e?ciency comparable to those found in biological entities. This Special Issue on Biological and Biologically-inspired Communication contains the best papers from the Second International Conference on Bio- Inspired Models of Network, Information, and Computing Systems (BIONET- ICS 2007). The BIONETICS conference aims to bring together researchers and scientistsfromseveraldisciplines incomputerscienceandengineeringwhereb- inspired methods are investigated, as well as from bioinformatics, to deepen the information exchange and collaboration among the di?erent communities.
Download or read book Transactions on Computational Systems Biology VIII written by Corrado Priami and published by Springer. This book was released on 2007-10-28 with total page 108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences. It supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena. The six papers selected for this special issue cover a broad range of topics.
Download or read book Systems Biology and Bioinformatics written by Kayvan Najarian and published by CRC Press. This book was released on 2009-04-13 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The availability of molecular imaging and measurement systems enables today's biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods
Download or read book Computational Systems Biology written by Andres Kriete and published by Academic Press. This book was released on 2013-11-26 with total page 549 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. Logical information flow aids understanding of basic building blocks of life through disease phenotypes Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.
Download or read book Bioinformatics and the Cell written by Xuhua Xia and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological and biomedical sciences are becoming more interdisciplinary, and scientists of the future need inte rdisciplinary training instead of the conventional disciplinary training. Just as Sean Eddy (2005) wiselypointed out that sending monolingual diplomats to the United Nations maynot enhance international collaborations, combining strictly disciplinary scientists trained in either mathematics, computational science or molecular biology will not create a productive inte rdisciplinary team ready to solve interdisciplinary problems. Molecular biology is an interdiscip linary science back in its heyday, and founders of molecular biology were ofte n interdisciplinary scientists. Indeed, Francis Crick considered himself as “a mixture of crystallographer, biophysicist, biochemist, and geneticist” (Crick, 1965). Because it was too cumbersome to explain to people that he was such a mixture, the term “molecular biologist” came handy. To get the crystallographer, biophysicist, biochemist, and geneticist within hi mself to collaborate with each other probably worked better than a team with a crystallographer, a biophysicist, a biochemist and a geneticist who maynot even be interested in each other’s problems.
Download or read book A New Kind of Computational Biology written by Parimal Pal Chaudhuri and published by Springer. This book was released on 2018-09-26 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reflects more than three decades of research on Cellular Automata (CA), and nearly a decade of work on the application of CA to model biological strings, which forms the foundation of 'A New Kind of Computational Biology' pioneered by the start-up, CARLBio. After a brief introduction on Cellular Automata (CA) theory and functional biology, it reports on the modeling of basic biological strings with CA, starting with the basic nucleotides leading to codon and anti-codon CA models. It derives a more involved CA model of DNA, RNA, the entire translation process for amino acid formation and the evolution of protein to its unique structure and function. In subsequent chapters the interaction of Proteins with other bio-molecules is also modeled. The only prior knowledge assumed necessary is an undergraduate knowledge of computer programming and biology. The book adopts a hands-on, “do-it-yourself” approach to enable readers to apply the method provided to derive the CA rules and comprehend how these are related to the physical ‘rules’ observed in biology. In a single framework, the authors have presented two branches of science – Computation and Biology. Instead of rigorous molecular dynamics modeling, which the authors describe as a Bottoms-Up model, or relying on the Top-Down new age Artificial Intelligence (AI) and Machine Language (ML) that depends on extensive availability of quality data, this book takes the best from both the Top-Down and Bottoms-up approaches and establishes how the behavior of complex molecules is represented in CA. The CA rules are derived from the basic knowledge of molecular interaction and construction observed in biological world but mapped to a few subset of known results to derive and predict results. This book is useful for students, researchers and industry practitioners who want to explore modeling and simulation of the physical world complex systems from a different perspective. It raises the inevitable the question – ‘Are life and the universe nothing but a collection of continuous systems processing information’.
Download or read book Transactions on Computational Systems Biology II written by Alexander Zelikovsky and published by Springer Science & Business Media. This book was released on 2005-11-04 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems oriented point of view of biological phenomena. This second volume of the Transactions on Computational Systems Biology is devoted to considerably extended versions of selected papers presented at the International Workshop on Bioinformatics Research and Applications (IWBRA 2005), part of the International Conference on Computational Science (ICCS 2005), which took place at Emory University, Atlanta, Georgia, USA, in May 2005. The ten papers selected for the special issue cover a wide range of bioinformatics research such as problems in RNA structure prediction, coding schemes and structural alphabets for protein structure prediction, novel techniques for efficient gene transfer in phylogenetic networks, practical algorithms minimizing recombinations in pedigree phasing, parallel implementation in Open MP for finding the corresponding shortest edit distance between two signed gene permutations, and bioinformatics problems in DNA microarrays.
Download or read book Computational Systems Biology written by Jason McDermott and published by . This book was released on 2009-01-01 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: The recent confluence of high throughput methodology for biological data gathering, genome-scale sequencing, and computational processing power has driven a reinvention and expansion of the way we identify, infer, model, and store relationships between molecules, pathways, and cells in living organisms. In Computational Systems Biology, expert investigators contribute chapters which bring together biological data and computational and/or mathematical models of the data to aid researchers striving to create a system that provides both predictive and mechanistic information for a model organism. The volume is organized into five major sections involving network components, network inference, network dynamics, function and evolutionary system biology, and computational infrastructure for systems biology. As a volume of the highly successful Methods in Molecular Biology series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Comprehensive and up-to-date, Computational Systems Biology serves to motivate and inspire all those who wish to develop a complete description of a biological system.
Download or read book Transactions on Computational Systems Biology III written by Corrado Priami and published by Springer Science & Business Media. This book was released on 2005-12-12 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems-oriented point of view of biological phenomena. This, the third Transactions on Computational Systems Biology volume, edited by Emanuela Merelli, Pedro Pablo Gonzalez and Andrea Omicini, is devoted to considerably extended versions of selected papers presented at the International Workshop on Network Tools and Applications in Biology (NETTAB 2004), held at the University of Camerino, in Camerino, Italy, in September 2004. Dedicated especially to models and metaphors from biology to bioinformatics tools, the 10 papers selected for the special issue cover a wide range of bioinformatics research such as data visualisation, protein/RNA structure prediction, motif finding, modelling and simulation of protein interaction, genetic linkage analysis, and notations and models for systems biology.
