Download or read book Systemic Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders written by Nodar Prokof'evich Mitagvariia and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Systemic Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders written by Nodar P. Mitagvaria and published by . This book was released on 2018-10-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The I. Beritashvili Center of Experimental Biomedicine was established in 2010 on the basis of merging four well-known Georgian research institutes. They are: The I. Beritashvili Institute of Physiology, one of the most prominent research centers of Georgia, where basic and applied research in different fields of neurophysiology has been conducted since 1935; the Institute of Molecular Biology and Biophysics; the Center for Radiology and Radiation Ecology, which for many years operated as departments at the I. Beritashvili Institute of Physiology; and one of the leading research centers for Georgia: The Center of Experimental Neurology. This edited book is the second volume containing chapters constituting the research priorities of the I. Beritashvili Center of Experimental Biomedicine and covers the experimental study of fundamental issues in the functioning of physiological (mainly, neurophysiological) mechanisms during normal and pathological conditions. The first book Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders published by Nova Science Publishers Inc. in 2015, was also devoted to the same general problems. In the present edited book, particular attention is drawn to the study of extremely important processes underlying the basic mechanisms and disorders of various phenomenon of integrative activity of the brain: General behavior, learning and memory processes, the sleep-wakefulness cycle, regulation of adequate blood supply, hormesis, vision, depression, experimental comatose state, epilepsy, tumor diseases, pain and analgesia, the state of anxiety and aggression. All of the mentioned processes are studied on the molecular, cellular and systemic levels of their organization. It has to be noted herewith that each chapter within the collection of works represents the results of separate, independent studies implemented by different scientific departments of the Center; therefore, the chapters are not directly related to each other and have been arranged alphabetically based on the surnames of the authors. The authors would like to take this opportunity and present to the reader the scientific and institutional infrastructure of the Center, which consists of departments and laboratories. Nowadays, the Center is comprised of seven departments: Neurophysiology, Membranology, Biochemistry, Blood Circulation and Metabolism, Neurotoxicology, Biophysics and Radiobiology and nine laboratories: Behavior and Cognitive Functions, Physiology of Vision, Neurobiology of Sleep-Wakefulness Cycle, Ultra- and Nanoarchitectonics of the Brain, Experimental Neurology, Pain and Analgesia, Bioinformatics, Structure and Function of Genomes, and the Problems of Radiation Safety. In addition to bilateral scientific cooperation with many famous European and American scientific institutions, the Center is a member of the International Science Consortium From Molecular to Cellular Events in Human Pathologies, of which the 2015 Annual Meeting was held in Tbilisi. The authors are sure that readers are fully aware of the theoretical and practical importance of the research related to problems of systemic, cellular and molecular mechanisms of physiological functions and their disorders. The presented collection of works contains the results of relevant research conducted over the last three years (2015-2018). The authors will be very grateful for any feedback, recommendations and suggestions regarding their research for the implementation of which they have invested a lot of effort, time, knowledge and experience.
Download or read book Systemic Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders written by Nodar Prokof'evich Mitagvariia and published by . This book was released on 2018 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The I. Beritashvili Center of Experimental Biomedicine was established in 2010 on the basis of merging four well-known Georgian research institutes. They are: The I. Beritashvili Institute of Physiology, one of the most prominent research centers of Georgia, where basic and applied research in different fields of neurophysiology has been conducted since 1935; the Institute of Molecular Biology and Biophysics; the Center for Radiology and Radiation Ecology, which for many years operated as departments at the I. Beritashvili Institute of Physiology; and one of the leading research centers for Georgia: The Center of Experimental Neurology.This edited book is the second volume containing chapters constituting the research priorities of the I. Beritashvili Center of Experimental Biomedicine and covers the experimental study of fundamental issues in the functioning of physiological (mainly, neurophysiological) mechanisms during normal and pathological conditions. The first book - Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders - published by Nova Science Publishers Inc. in 2015, was also devoted to the same general problems.In the present edited book, particular attention is drawn to the study of extremely important processes underlying the basic mechanisms and disorders of various phenomenon of integrative activity of the brain: General behavior, learning and memory processes, the sleep-wakefulness cycle, regulation of adequate blood supply, hormesis, vision, depression, experimental comatose state, epilepsy, tumor diseases, pain and analgesia, the state of anxiety and aggression. All of the mentioned processes are studied on the molecular, cellular and systemic levels of their organization. It has to be noted herewith that each chapter within the collection of works represents the results of separate, independent studies implemented by different scientific departments of the Center; therefore, the chapters are not directly related to each other and have been arranged alphabetically based on the surnames of the authors. The authors would like to take this opportunity and present to the reader the scientific and institutional infrastructure of the Center, which consists of departments and laboratories.Nowadays, the Center is comprised of seven departments: Neurophysiology, Membranology, Biochemistry, Blood Circulation and Metabolism, Neurotoxicology, Biophysics and Radiobiology and nine laboratories: Behavior and Cognitive Functions, Physiology of Vision, Neurobiology of Sleep-Wakefulness Cycle, Ultra- and Nanoarchitectonics of the Brain, Experimental Neurology, Pain and Analgesia, Bioinformatics, Structure and Function of Genomes, and the Problems of Radiation Safety.In addition to bilateral scientific cooperation with many famous European and American scientific institutions, the Center is a member of the International Science Consortium "From Molecular to Cellular Events in Human Pathologies", of which the 2015 Annual Meeting was held in Tbilisi.The authors are sure that readers are fully aware of the theoretical and practical importance of the research related to problems of systemic, cellular and molecular mechanisms of physiological functions and their disorders. The presented collection of works contains the results of relevant research conducted over the last three years (2015-2018).The authors will be very grateful for any feedback, recommendations and suggestions regarding their research for the implementation of which they have invested a lot of effort, time, knowledge and experience.
Download or read book Systemic Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders Third Book Proceedings of I Beritashvili Center for Experimental Biomedicine 2021 written by Nargiz Nachkebia and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ivane Beritashvili Center of Experimental Biomedicine was established in 2010 on the basis of the well-known Ivane Beritashvili Institute of Physiology, the most prominent research center of Georgia, where basic and applied research in different fields of neurophysiology has been conducted since its foundation.Professor Ivane Beritashvili was a famous Georgian scientist who gained international recognition during his lifetime. He was one of the founders and members of the Georgian Academy of Sciences and a member of three academies of sciences of the former Soviet Union. He was an honorary member of the New York Academy of Sciences, the American Society of Electroencephalography, the Royal Society of England, the American Society of Biological Psychiatry, and an honorary member of the International Brain Research Organization. He was an honored scientist of Georgia, a laureate of the State Prize, and a recipient of many orders and medals.Ivane Beritashvili is remembered in history as a person who founded the Department of Physiology at the newly opened Tbilisi State University. He developed physiological terminology in Georgian, wrote a textbook of physiology in Georgian for the students of the university, raised successful scientists from the first generation of his students, and founded the Georgian School of Physiology. In 1935, he founded the Institute of Physiology in Tbilisi, which soon gained recognition and became well-respected by a wide range of foreign scientists who often visited Georgia. In 2010, three scientific institutions were merged with the Ivane Beritashvili Institute of Physiology - the Institute of Molecular Biology and Biophysics, the Center of Radiobiology and Radiation Ecology and the Center of Experimental Neurology, the first two of which, for many years, were the departments of the Institute of Physiology. This edited book is the third such compilation containing chapters that represent the research priorities of the Ivane Beritashvili Center of Experimental Biomedicine, which covers the experimental study of fundamental issues in the functioning of physiological (mainly neurophysiological) mechanisms during normal and pathological conditions. The first and second books - "Systemic, Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders" - published by Nova Science Publishers Inc. in 2015 and 2018, were also devoted to the same general problems.In the present edited book, particular attention is drawn to the study of extremely important processes underlying the basic mechanisms and disorders of various phenomenon of integrative activity of the brain: general behavior, learning and memory, the sleep-wakefulness cycle, regulation of adequate blood supply, hormesis, epilepsy, depression, sleep disorders, pain and analgesia. All of the mentioned processes are studied on the molecular, cellular and systemic levels of their organization. It has to be noted that each chapter, within the collection of works, represents the results of separate, independent studies implemented by different scientific departments of the center. Therefore, the chapters are not directly related to each other and have been arranged alphabetically based on the surname of the authors. The authors would like to take this opportunity to present to the reader the scientific and institutional infrastructure of the center, which consists of departments and laboratories. Nowadays the center consists of seven departments: Neurophysiology, Membranology, Biochemistry, Blood Circulation and Metabolism, Neurotoxicology, Membranology, Biophysics and Radiobiology and nine laboratories: Neurobiology of Sleep-Wakefulness Cycle, Vision Physiology, Behavior and Cognitive Functions, Brain Ultra- and Nano-Architectonics, Experimental Neurology, Pain and Analgesia, Structure and Functions of Genomes, Bioinformatics, and the Problems of Radiation Safety.In addition to the bilateral scientific cooperation with famous European and U.S. scientific institutions, the center is a member of the International Science Consortium "From Molecule to Cellular Events in Human Pathologies", the annual meeting of which was held in Tbilisi in 2015.The authors are confident that the readers are fully aware of the theoretical and practical importance of the research related to the problems of systemic, cellular and molecular mechanisms of physiological functions and their disorders. The presented collection of works contains the results of relevant research conducted over the last three years (2019-2021).The authors will be grateful for feedback, recommendations and suggestions regarding their research, in the implementation of which they have invested a lot of effort, knowledge and experience.
Download or read book Cellular Endocrinology in Health and Disease written by Alfredo Ulloa-Aguirre and published by Academic Press. This book was released on 2021-02-19 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts Explores endocrine cells biology in normal and pathologic conditions Covers new aspects of endocrine cell function in distinct tissues Provides a view into the biological effect in local and systemic levels 15 new chapters covering the recent developments in the field
Download or read book Mechanisms of Cell Death written by Zahra Zakeri and published by . This book was released on 1999 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contains papers from a July 1998 conference held at the Queens College Campus of the City University of New York. Papers are arranged in sections on mechanisms and general considerations, programmed (developmental) cell death, and cell death and pathological and clinical situations. Specific topics
Download or read book Nitric Oxide written by Louis J. Ignarro and published by Academic Press. This book was released on 2000-09-13 with total page 1023 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide Authored by world experts on nitric oxide Includes an overview of basic principles of biology and chemical biology Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense
Download or read book Molecular Neuropathology written by Gareth W. Roberts and published by Cambridge University Press. This book was released on 1995-06-08 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an introduction to the essential techniques required for studying the molecular biology of brain disease. The approaches and strategies for investigations of gene structure and regulation are described with reference to the molecular genetics of prion and Alzheimer's disease. The effects of aberrant gene regulation can also be examined at the protein level by immunocytochemistry and autoradiography. Improved understanding of basic biology has resulted in new approaches to animal models using transgenic techniques and new therapeutic approaches. The volume is structured to illustrate all these approaches and demonstrate the practice and promise of molecular neuropathology.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Exercise Genomics written by Linda S. Pescatello and published by Springer Science & Business Media. This book was released on 2011-03-23 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exercise Genomics encompasses the translation of exercise genomics into preventive medicine by presenting a broad overview of the rapidly expanding research examining the role of genetics and genomics within the areas of exercise performance and health-related physical activity. Leading researchers from a number of the key exercise genomics research groups around the world have been brought together to provide updates and analysis on the key discoveries of the past decade, as well as lend insights and opinion about the future of exercise genomics, especially within the contexts of translational and personalized medicine. Clinicians, researchers and health/fitness professionals will gain up-to-date background on the key findings and critical unanswered questions across several areas of exercise genomics, including performance, body composition, metabolism, and cardiovascular disease risk factors. Importantly, basic information on genomics, research methods, and statistics are presented within the context of exercise science to provide students and professionals with the foundation from which to fully engage with the more detailed chapters covering specific traits. Exercise Genomics will be of great value to health/fitness professionals and graduate students in kinesiology, public health and sports medicine desiring to learn more about the translation of exercise genomics into preventive medicine.
Download or read book The COMBINE Study written by Helen M. Pettinati and published by . This book was released on 2005 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Academic Press. This book was released on 2014-12-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Ross Wilson Anatomy and Physiology in Health and Illness E Book written by Anne Waugh and published by Elsevier Health Sciences. This book was released on 2018-07-12 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of the hugely successful Ross and Wilson Anatomy & Physiology in Health and Illness continues to bring its readers the core essentials of human biology presented in a clear and straightforward manner. Fully updated throughout, the book now comes with enhanced learning features including helpful revision questions and an all new art programme to help make learning even easier. The 13th edition retains its popular website, which contains a wide range of ‘critical thinking’ exercises as well as new animations, an audio-glossary, the unique Body Spectrum© online colouring and self-test program, and helpful weblinks. Ross and Wilson Anatomy & Physiology in Health and Illness will be of particular help to readers new to the subject area, those returning to study after a period of absence, and for anyone whose first language isn’t English. Latest edition of the world’s most popular textbook on basic human anatomy and physiology with over 1.5 million copies sold worldwide Clear, no nonsense writing style helps make learning easy Accompanying website contains animations, audio-glossary, case studies and other self-assessment material, the unique Body Spectrum© online colouring and self-test software, and helpful weblinks Includes basic pathology and pathophysiology of important diseases and disorders Contains helpful learning features such as Learning Outcomes boxes, colour coding and design icons together with a stunning illustration and photography collection Contains clear explanations of common prefixes, suffixes and roots, with helpful examples from the text, plus a glossary and an appendix of normal biological values. Particularly valuable for students who are completely new to the subject, or returning to study after a period of absence, and for anyone whose first language is not English All new illustration programme brings the book right up-to-date for today’s student Helpful ‘Spot Check’ questions at the end of each topic to monitor progress Fully updated throughout with the latest information on common and/or life threatening diseases and disorders Review and Revise end-of-chapter exercises assist with reader understanding and recall Over 150 animations – many of them newly created – help clarify underlying scientific and physiological principles and make learning fun
Download or read book Integrative Physiology in the Proteomics and Post Genomics Age written by Wolfgang Walz and published by Springer Science & Business Media. This book was released on 2005-03-22 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: The advent of molecular techniques has shifted the focus of physiology from its traditional role as an integrative science concerned with the study of regulatory mechanisms leading to adaptation and homeostasis, to a field preoccupied with the problems and challenges inherent in those techniques. In Integrative Physiology in the Proteomics and Post-Genomics Age, internationally recognized researchers highlight the major questions and accomplishments of modern physiological research and demonstrate that modern molecular methods can well be incorporated and strengthen the original integrative perspectives of physiology set out by Claude Bernard's concept of the "milieu interieur." Among the critical issues discussed are the place of functional genomics in regulatory physiology, the role of model systems in integrative physiology, the function of neural circuits in behavior and consciousness, and the influence of external challenges to the whole body and the environment on genes. The question of integrative physiology in curriculum design for the health sciences is also discussed. Perceptive and timely, Integrative Physiology in the Proteomics and Post-Genomics Age bridges the gap between molecular biology and whole body function, establishing the future of physiology as an integrative science based on new molecular insights.
Download or read book The Metabolic Ghetto written by Jonathan C. K. Wells and published by Cambridge University Press. This book was released on 2016-07-21 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: A multidisciplinary analysis of the role of nutrition in generating hierarchical societies and cultivating a global epidemic of chronic diseases.
