Download or read book Synthetic Studies in the Chemistry of Nitrogen containing Heterocyclic Compounds written by K. Vaughan and published by . This book was released on 1967 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles 2 Volume Set written by Ana Maria Faisca Phillips and published by John Wiley & Sons. This book was released on 2022-04-11 with total page 759 pages. Available in PDF, EPUB and Kindle. Book excerpt: More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles An authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles Widely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles offers R&D professionals the opportunity to easily access a collection of the latest relevant research in the area. In the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 also offers readers: A thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics Comprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives Practical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds In-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles Perfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.
Download or read book More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles 2 Volume Set written by Ana Maria Faisca Phillips and published by John Wiley & Sons. This book was released on 2022-04-04 with total page 759 pages. Available in PDF, EPUB and Kindle. Book excerpt: More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles An authoritative collection of resources discussing the latest trends in the synthesis of nonaromatic nitrogen heterocycles Widely distributed in nature, nitrogen heterocycles are extremely common in synthetic substances found in pharmaceuticals, agrochemicals, and materials. The literature is evolving rapidly and explores newly emerging structures and medicines. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles offers R&D professionals the opportunity to easily access a collection of the latest relevant research in the area. In the second two-volume set of this practical reference distinguished researcher Dr. Ana Maria M. M. Faisca Phillips delivers a collection of resources focusing on the newest and most widely applicable trends emerging in synthetic strategies for nonaromatic nitrogen heterocycles. With coverage of topics including organocatalysis, cascade reactions, flow chemistry in synthesis, cycloaddition reactions, metathesis, cross-coupling reactions, and electrochemistry, the book provides quick access to critical new avenues of synthesis. More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 also offers readers: A thorough introduction to recent advances in the design and synthesis of cyclic peptidomimetics Comprehensive explorations of fused heterocycles and transition metal promoted synthesis of isoindoline derivatives Practical discussions of 1,4-diazepane ring-based systems and recent advances in the synthesis of azepane-based compounds In-depth examinations of strained aziridinium ions, asymmetric organocatalysis in alternative media, and the electrochemical synthesis of non-aromatic N-heterocycles Perfect for academic and industrial researchers in organic chemistry and synthesis, organometallic chemistry, pharmaceutical chemistry catalysis, and sustainable chemistry, More Synthetic Approaches to Nonaromatic Nitrogen Heterocycles: Volume 1 and 2 is an indispensable reference for anyone seeking an authoritative source of information on new and emerging trends in synthesis.
Download or read book Nitrogen Containing Molecules written by Dimitris Matiadis and published by . This book was released on 2021-11 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: - A total of 16 original research articles. - Contributions from 10 countries from 3 continents. - Organic synthesis towards novel heterocyclic compounds. - Fully characterized inorganic and organic molecules including X-ray crystallographic analysis. - Cyclization reactions, reactivity of aromatic compounds and improved synthetic methodologies of important intermediate compounds.
Download or read book Fundamentals of Heterocyclic Chemistry written by Louis D. Quin and published by John Wiley & Sons. This book was released on 2010-07-08 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic chemistry is of prime importance as a sub-discipline of Organic Chemistry, as millions of heterocyclic compounds are known with more being synthesized regularly Introduces students to heterocyclic chemistry and synthesis with practical examples of applied methodology Emphasizes natural product and pharmaceutical applications Provides graduate students and researchers in the pharmaceutical and related sciences with a background in the field Includes problem sets with several chapters
Download or read book Synthesis of Naturally Occurring Nitrogen Heterocycles from Carbohydrates written by El Sayed H. El Ashry and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbohydrates are widely distributed in nature and widely available, and so are considered as a promising feedstock for the preparation of many organic chemical compounds. They are particularly useful in the preparation of nitrogen heterocycles because of their related structural characteristics and easy availability. Synthesis of Naturally Occurring Nitrogen Heterocycles from Carbohydrates will review the recent literature dealing with use of carbohydrates as raw materials in the synthesis of these materials. The text contains six chapters arranged according to the complexity of the heterocyclic compounds discussed, ranging from five to seven membered rings and from single to multiple fused rings. The book provides a detailed discussion of the various synthetic approaches to these compounds, using carbohydrate starting materials, and does not merely reference synthetic methodology but attempts to give as much detail as possible on the actual experimental conditions used, in such a way that the chemist can use the information directly to design a multi-step synthesis. It discusses the different approaches to the synthesis of a wide range of naturally occurring nitrogen heterocycles in a format that enables the reader to make comparisons and decisions on whether to use a certain procedure, to modify it, or to devise a new synthetic methodology.
Download or read book Recent Advances in Synthesizing and Utilizing Nitrogen containing Heterocycles written by Hyun-Joon Ha and published by Frontiers Media SA. This book was released on 2024-05-31 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nitrogen-containing heterocycles, so-called aza-heterocycles, are widely found in natural products, pharmaceuticals, agrochemicals, and functional materials, and thus their synthesis has long been studied intensively. In addition, their preparation and utilization as synthons or intermediates from one to another are also developed to build higher and more complex aza-heterocycles. Some of them are also used as ligands for metal catalysts and organocatalysts. Despite many studies of the synthesis and utilization of nitrogen-containing heterocycles, a more efficient and general preparation is still required to diversify the structural backbones and improve their biological activities. Their usage as ligands and catalysts is also under expansion in various reactions.
Download or read book Heterocyclic Chemistry written by John A. Joule and published by John Wiley & Sons. This book was released on 2013-05-28 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has so closely matched the requirements of its readership over the years that it has become the first choice for chemists worldwide. Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, the vast majority of organic work done in the pharmaceutical and agrochemical industries is heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains the principal objective of earlier editions – to teach the fundamentals of heterocyclic reactivity and synthesis in a way that is understandable to second- and third-year undergraduate chemistry students. The inclusion of more advanced and current material also makes the book a valuable reference text for postgraduate taught courses, postgraduate researchers, and chemists at all levels working with heterocyclic compounds in industry. Fully updated and expanded to reflect important 21st century advances, the fifth edition of this classic text includes the following innovations: Extensive use of colour to highlight changes in structure and bonding during reactions Entirely new chapters on organometallic heterocyclic chemistry, heterocyclic natural products, especially in biochemical processes, and heterocycles in medicine New sections focusing on heterocyclic fluorine compounds, isotopically labeled heterocycles, and solid-phase chemistry, microwave heating and flow reactors in the heterocyclic context Essential teaching material in the early chapters is followed by short chapters throughout the text which capture the essence of heterocyclic reactivity in concise resumés suitable as introductions or summaries, for example for examination preparation. Detailed, systematic discussions cover the reactivity and synthesis of all the important heterocyclic systems. Original references and references to reviews are given throughout the text, vital for postgraduate teaching and for research scientists. Problems, divided into straightforward revision exercises, and more challenging questions (with solutions available online), help the reader to understand and apply the principles of heterocyclic reactivity and synthesis.
Download or read book Studies in Chemistry of Oxygen Nitrogen Heterocycles written by Mohammad Asad and published by . This book was released on 2012-02 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The work of the book is devoted to a study of a series of organic reactions from readily available and less costly starting materials such as coumarins, pyrazoles, and chromones. These heterocyclic compounds were readily converted to polyketomethylene compounds by treatment with active methylene compounds such as triacetic acid lactone, dimedone, 3-methyl-1-phenyl-5-pyrazolone and nitrogenous bases such as hydrazine hydrate, phenyl-hydrazine, hydroxylamine respectively under different reaction conditions and the structures of all new compounds were identified on the basis of IR, NMR, and mass spectroscopy. Some of these synthesized compounds have been investigated for anti-inflammatory, analgesic, antipyretic and antibacterial activities. Most of the compounds have been found to possess significant activities and their effect was compared with the standard drugs.
Download or read book N Sulfonated N Heterocycles written by Galal H. Elgemeie and published by Elsevier. This book was released on 2022-08-30 with total page 523 pages. Available in PDF, EPUB and Kindle. Book excerpt: N-Sulfonated-N-Heterocycles covers the synthesis, chemistry and biological applications of these compounds, focusing on pioneering synthetic approaches, mechanistic insights and their limitations, as well as recent advances in this field. The synthesis of some of N-sulfonated N-heterocycles and their transformation to other useful cyclic and acyclic compounds are discussed, as well as their uses as useful intermediates in the preparation of polymeric and medicinal materials. This book includes detailed methods and protocols, and the focus on applications makes this resource an essential guide for all researchers in the area of organic, medicinal and polymeric synthetic study. Reviews the use of N-sulfonated N-heterocycles as important precursors for the synthesis of biologically active compounds Includes information on synthetically useful transformations of N-sulfonated N-heterocycles Covers a wide synthetic methods used for an important branch of heterocycles and their biological evaluation in detail Features over 500 schemes to illustrate different synthetic pathways and reactions of N-sulfonated N-heterocycles
Download or read book Heterocyclic Compounds written by Kristian Nylund and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocyclic compounds are organic compounds containing at least one atom of carbon, and at least one element other than carbon, such as sulphur, oxygen or nitrogen within a ring structure. These structures may comprise either simple aromatic rings or non-aromatic rings. Some examples are pyridine (C5H5N), pyrimidine (C4H4N2) and dioxane (C4H8O2). Many heterocyclic compounds, including some amines, are carcinogenic. This book details the proposed mechanisms of Gewald-like reactions and the wide scope of substituted 2-aminothiophenes for real life applications. Literary information about synthesis methods, structure, physical-chemical and biological properties is summarised, and also information about conversion of adamantyl-1 and adamantyl-2 imidazole and benzimidazole derivatives is given. In addition, 3-acetylindole derivatives have been in the centre of attention of researchers over many years due to the high practical value of these compounds. This book presents a survey of the literature on 3-acetylindoles chemistry and provides useful and up-to-date data for medicinal chemists.
Download or read book Cancer Leading Proteases written by Satya Prakash Gupta and published by Academic Press. This book was released on 2020-02-03 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases. Explains the role of proteases in the biology of cancer Discusses how proteases can be used as potential drug targets or as diagnostic and prognostic biomarkers Covers a wide range of cancers and provides detailed discussions on protease examples
Download or read book Au Catalyzed Synthesis and Functionalization of Heterocycles written by Marco Bandini and published by Springer. This book was released on 2016-07-01 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field. All chapters from Topics in Heterocyclic Chemistry are published Online First with an individual DOI. In references, Topics in Heterocyclic Chemistry is abbreviated as Top Heterocycl Chem and cited as a journal
Download or read book Asymmetric Synthesis of Nitrogen Heterocycles written by Jacques Royer and published by John Wiley & Sons. This book was released on 2009-08-04 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, all aspects of the topic are presented in a compact manner. The book is clearly structured, and divided into two sections -- asymmetric synthesis of heterocycles containing only one nitrogen and that of those with more than one nitrogen as a heteroatom -- such that the necessary information may be found at a glance. The international team of authors provides important experimental procedures, including industrial applications. Essential for synthetic chemists in pharmaceutical and agrochemical chemistry.
Download or read book Thematic Collections of Organic Syntheses Synthesis of Nitrogen Heterocyclic Compounds written by Rick L. Danheiser and published by Wiley. This book was released on 2014-04-01 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides an overview of the synthesis of nitrogen containing compounds, including an introduction, comments and suggestions of procedures discussed, detailed, experimental procedures verified in an independent laboratory, and a bibliography of key reviews and monographs on the reaction type. The style, level, and organization provide a resource appropriate for individual researchers as well as students in courses such as advanced organic chemistry.
Download or read book Azoles written by Aleksey Kuznetsov and published by BoD – Books on Demand. This book was released on 2021-06-30 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Azoles are a broad and promising class of five-membered heterocyclic compounds containing from one up to five nitrogen atom(s) that can also contain sulfur or oxygen atoms. Widely used as potent antifungal agents, various azole derivatives have also demonstrated many other promising biological properties. This book covers studies of several types of thiazole-based heterocyclic scaffolds, the development of 4-thiazolidinone and thiazole derivatives with heterocyclic fragments as potential candidates for new drugs against trypanosomiasis, numerous synthetic approaches for the synthesis of 1,2,3-triazoles, the application of N-azole, N,S-azole, and N,O-azole as well as their derivatives as retarders of metallic corrosion, and the integration of azoles in materials used for renewable energy processing and applications and wood treatment.
Download or read book Ring Nitrogen and Key Biomolecules written by E.G. Brown and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nitrogen-containing ring structures are at the hub of metabolism and include ATP, nucleic acids, many coenzymes, metabolic regulators and integrators such as adenosine and GTP, signalling compounds such as cyclic nucleotides and plant cytokinins and biochemically functional pigmets of which haemoglobin, the cytochromes and chlorophyll are examples. This important book collates and integrates current knowledge of all the biologically important N-heterocyclic compounds, covering the relationship between their chemical structures and physiological functions within this key group of compounds. Few biochemical reaction sequences do not involve one of these compounds as a substrate, product or coenzyme and a full understanding of the interrelationship between their structure and function is vital for all those woorking in the field of biochemistry. Professor Eric Brown who has a huge wealth of experience in teaching and research on these compounds has written a very comprehensible and thorough book which will be of great value for advanced students and researchers in biochemistry and those at the interfacing subject areas of chemistry, biology and pharmacology including all those employed in researching biological function within pharmaceutical companies.
