Download or read book Synthetic Biology for the Sustainable Production of Biochemicals in Engineered Microbes written by Shuobo Shi and published by Frontiers Media SA. This book was released on 2022-09-23 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Systems Metabolic Engineering written by Christoph Wittmann and published by Springer Science & Business Media. This book was released on 2012-06-15 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Metabolic Engineering is changing the way microbial cell factories are designed and optimized for industrial production. Integrating systems biology and biotechnology with new concepts from synthetic biology enables the global analysis and engineering of microorganisms and bioprocesses at super efficiency and versatility otherwise not accessible. Without doubt, systems metabolic engineering is a major driver towards bio-based production of chemicals, materials and fuels from renewables and thus one of the core technologies of global green growth. In this book, Christoph Wittmann and Sang-Yup Lee have assembled the world leaders on systems metabolic engineering and cover the full story – from genomes and networks via discovery and design to industrial implementation practises. This book is a comprehensive resource for students and researchers from academia and industry interested in systems metabolic engineering. It provides us with the fundaments to targeted engineering of microbial cells for sustainable bio-production and stimulates those who are interested to enter this exiting research field.

Download or read book Synthetic Biology Metabolic Engineering written by Huimin Zhao and published by Springer. This book was released on 2017-10-27 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Download or read book Synthetic Biology written by Huimin Zhao and published by Academic Press. This book was released on 2013-03-21 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development

Download or read book Biomanufacturing for Sustainable Production of Biomolecules written by Vijai Singh and published by Springer Nature. This book was released on 2023-01-26 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book elucidates the sustainable production of commercially important biomolecules in medicines, food, and beverage processing, through biological systems, including microorganisms, animal cells, plant cells, tissues, enzymes, and in vitro. It discusses promising technologies for the manipulation of cells including, genetic engineering, synthetic biology, genome editing, and metabolic engineering. The initial chapters of the book introduce topics on biomanufacturing, circular economy, strain design and improvement, upstream and downstream processing. The subsequent chapters cover artificial intelligence-assisted production, designer cell factories, biosensors for monitoring biomolecules, different cells factories, biosynthetic pathways, and genome editing approaches for scale-up biomanufacturing. Lastly, the book discusses the opportunities and challenges of implementing biological systems for the production of biomolecules. ​This book is a valuable source for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand biomanufacturing for the sustainable production of biomolecules.

Download or read book Engineering of Microbial Biosynthetic Pathways written by Vijai Singh and published by Springer Nature. This book was released on 2020-07-16 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the basic and advanced metabolic engineering technologies used to generate natural metabolites and industrially important biomolecules. Metabolic engineering has the potential to produce large quantities of valuable biomolecules in a renewable and sustainable manner by extending or modifying biosynthetic pathways in a wide range of organisms. It has been successfully used to produce chemicals, drugs, enzymes, amino acids, antibiotics, biofuels, and industrially important pharmaceuticals. The book comprehensively reviews the various metabolites detection, extraction and biosensors and the metabolic engineering of microbial strains for the production of industrially useful enzymes, proteins, organic acids, vitamins and antibiotics, therapeutics, chemicals, and biofuels. It also discusses various genetic engineering and synthetic biology tools for metabolic engineering. In closing, the book discusses ethical, patenting and regulatory issues in the metabolic engineering of microbes. This book is a valuable source not only for beginners in metabolic engineering, but also students, researchers, biotechnology and metabolic engineering based company.

Download or read book Biomolecular Engineering Solutions for Renewable Specialty Chemicals written by R. Navanietha Krishnaraj and published by John Wiley & Sons. This book was released on 2021-11-11 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover biomolecular engineering technologies for the production of biofuels, pharmaceuticals, organic and amino acids, vitamins, biopolymers, surfactants, detergents, and enzymes In Biomolecular Engineering Solutions for Renewable Specialty Chemicals, distinguished researchers and editors Drs. R. Navanietha Krishnaraj and Rajesh K. Sani deliver a collection of insightful resources on advanced technologies in the synthesis and purification of value-added compounds. Readers will discover new technologies that assist in the commercialization of the production of value-added products. The editors also include resources that offer strategies for overcoming current limitations in biochemical synthesis, including purification. The articles within cover topics like the rewiring of anaerobic microbial processes for methane and hythane production, the extremophilic bioprocessing of wastes to biofuels, reverse methanogenesis of methane to biopolymers and value-added products, and more. The book presents advanced concepts and biomolecular engineering technologies for the production of high-value, low-volume products, like therapeutic molecules, and describes methods for improving microbes and enzymes using protein engineering, metabolic engineering, and systems biology approaches for converting wastes. Readers will also discover: A thorough introduction to engineered microorganisms for the production of biocommodities and microbial production of vanillin from ferulic acid Explorations of antibiotic trends in microbial therapy, including current approaches and future prospects, as well as fermentation strategies in the food and beverage industry Practical discussions of bioactive oligosaccharides, including their production, characterization, and applications In-depth treatments of biopolymers, including a retrospective analysis in the facets of biomedical engineering Perfect for researchers and practicing professionals in the areas of environmental and industrial biotechnology, biomedicine, and the biological sciences, Biomolecular Engineering Solutions for Renewable Specialty Chemicals is also an invaluable resource for students taking courses involving biorefineries, biovalorization, industrial biotechnology, and environmental biotechnology.

Download or read book Current Developments in Biotechnology and Bioengineering written by Swati Joshi and published by Elsevier. This book was released on 2022-04-29 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designer Microbial Cell Factories: Metabolic Engineering and Applications, the latest release in the Current Developments in Biotechnology and Bioengineering series, provides a detailed overview of the biotechnological approaches and strategies used to generate engineered microbes and to facilitate the acceleration, modulation and diversion of metabolic pathways to get desired output such as production of value-added compound or biodegradation of xenobiotic pollutant. The book also highlights applied aspects of designer microbes in fields as diverse as agriculture, pharmaceuticals and bioremediation. Designer microbes generated through reprogramming the microbial cell factories (MCFs) provide an edge over their natural counterparts in terms of increased molecular diversity and selective chemistry. These bugs are becoming instrumental in several areas, including agriculture, environment and human health. Engineering microbes through directed evolution not only gives freedom from evolutionary constrains but also allow introduction of regulated and foreseeable functions into MCFs. Dedicated to the designing of microbes, covering state-of-the-art technological advancements in the field Includes applications of metabolic engineering in the field of agriculture, bioremediation, value-added products, therapeutics, and more Contains chapters dedicated to innovative approaches surrounding engineered microbial consortia Provides comprehensive details and helps users understand concepts

Download or read book Sustainable Production of Platform Chemicals Using Novel Synthetic Biology and Microbial Fermentations written by Laura Jeffrey and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthetic Biology and Metabolic Engineering in Plants and Microbes Part A Metabolism in Microbes written by and published by Academic Press. This book was released on 2016-07-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A, the new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Contains two volumes covering research methods in synthetic biology and metabolic engineering in plants and microbes Presents sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways

Download or read book Biomass Biofuels Biochemicals written by S.Venkata Mohan and published by Elsevier. This book was released on 2018-09-28 with total page 1146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomass, Biofuels, Biochemicals encompasses the potential of microbial electrochemical technologies, delineating their role in developing a technology for abating environmental crisis and enabling transformation to a sustainable future. The book provides new and futuristic methods for bioelectrogenesis, multiple product synthesis, waste remediation strategies, and electromicrobiology generation which are widely essential to individuals from industry, marketing, activists, writers, etc. In addition, it provides essential knowledge transfer to researchers, students and science enthusiasts on Microbial Electrochemical Technologies, detailing the functional mechanisms employed, various operational configurations, influencing factors governing the reaction progress and integration strategies. With these key topics and features, the book generates interest among a wide range of people related to renewable energy generation and sustainable environmental research. Depicts the holistic view of the multiple applications of Microbial Electrochemical Technologies (METs) in a unified comprehensible manner Provides strategic integrations of MET with various bioprocesses that are essential in establishing a circular biorefinery Widens the scope of the existing technologies, giving up-to date, state-of-the-art information and knowledge on research and commercialization Contains topics that are lucid, providing interdisciplinary knowledge on the environment, molecular biology, engineering, biotechnology, microbiology and economic aspects Includes more than 75 illustrations, figures, diagrams, flow charts, and tables for further study

Download or read book Synthetic Biology a Primer revised Edition written by Paul S. FREEMONT and published by World Scientific. This book was released on 2015-08-24 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology -- A Primer (Revised Edition) presents an updated overview of the field of synthetic biology and the foundational concepts on which it is built. This revised edition includes new literature references, working and updated URL links, plus some new figures and text where progress in the field has been made.The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely 'bottom-up' and 'top-down' engineering approaches. 'Top-down' engineering uses a conceptual framework of systematic design and engineering principles focused around the Design-Build-Test cycle and mathematical modelling. The 'bottom-up' approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch exploring the fundamental basis of living systems.Examples of cutting-edge applications designed using synthetic biology principles are presented, including: The book also describes the Internationally Genetically Engineered Machine (iGEM) competition, which brings together students and young researchers from around the world to carry out summer projects in synthetic biology. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences into synthetic biology research.Final year undergraduates, postgraduates and established researchers interested in learning about the interdisciplinary field of synthetic biology will benefit from this up-to-date primer on synthetic biology.

Download or read book Biomedical Engineering written by Phil Gilberts and published by Freegulls Publishing House. This book was released on with total page 55 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical engineering integrates the principles of biology, chemistry, and engineering to develop processes for the large-scale production of valuable biochemicals. This interdisciplinary field plays a crucial role in industries such as pharmaceuticals, biotechnology, food and beverage, and environmental engineering. One of the fundamental aspects of biochemical engineering is fermentation, which involves the controlled growth of microorganisms like bacteria, yeast, or fungi to produce desired compounds. These microorganisms can be genetically engineered or selected for their ability to synthesize specific products, such as antibiotics, vitamins, or biofuels. Biocatalysis is another key area within biochemical engineering, focusing on the use of enzymes or whole cells to catalyze chemical reactions. By harnessing the specificity and efficiency of biological catalysts, biocatalysis offers environmentally friendly and cost-effective solutions for chemical synthesis and manufacturing processes. Bioseparation techniques are essential for isolating and purifying target biomolecules from complex mixtures produced during fermentation or biocatalytic reactions. These techniques include filtration, chromatography, centrifugation, and membrane processes, which enable the recovery of high-purity products for further downstream processing. Bioprocess design involves the optimization of various parameters such as reactor configuration, operating conditions, and media composition to maximize product yield, quality, and efficiency. Computational modeling and simulation techniques play a crucial role in predicting and optimizing bioprocess performance, allowing engineers to design robust and scalable production systems. Overall, biochemical engineering combines scientific principles with engineering methodologies to develop sustainable and economically viable processes for the production of biochemicals with diverse applications in medicine, agriculture, energy, and the environment.

Download or read book Sustainable Production Innovations written by Alok Kumar Patel and published by John Wiley & Sons. This book was released on 2023-08-02 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: SUSTAINABLE PRODUCTION INNOVATIONS Presenting the latest technologies and practices in this ever-changing field, this groundbreaking new volume covers the gambit for providing solutions and practical applications of smart and efficient energy systems. The global and climate changes we are witnessing are primarily driven by factors such as rising population, economic growth, and industrialization. These changes have led to an increase in atmospheric CO2, pollution, deforestation, water scarcity, and hunger, among other pressing issues. To ensure a green and sustainable future, it is crucial to harness renewable resources for the production of fuels, chemicals, and materials. The book, Sustainable Production Innovations, addresses several bioprocesses that are integral to our daily lives, tackling important topics such as biofuel production, energy and food security, and wastewater management. The commercial interest in biotechnological processes has grown significantly due to their ability to utilize biocatalysts such as enzymes, bacteria, plant cells, or animal cells in bioreactors for the production of medications, health supplements, foods, biofuels, and chemicals. Switching to bioproducts offers key benefits such as the sustainability of third-generation biofuels, CO2 sequestration, effective waste utilization, and meeting the increasing demand for clean water. The book explores various procedures used in biomass biorefineries and bioprocessing for the production of biofuels, biobased chemicals, and bioproducts. It also delves into advancements in utilizing oleaginous microorganisms for biofuels and nutraceuticals, biological wastewater treatment, and microplastic detection techniques in water. Additionally, the book covers topics such as biolubricant technologies, bioprocessing of agricultural and forest waste, biotechnological approaches in the cosmetic industry, and large-scale applications of nanomaterials for water treatment. Authored by experts from leading biotechnology research groups around the world, the book comprises 13 chapters featuring the latest research in each subject. It is a valuable resource for scholars in chemical engineering, applied microbiology, biotechnology, agricultural biotechnology, environmental biotechnology, and related fields, offering new insights into the sustainable use of renewable energy and biochemicals. Professionals, including biochemical engineers, phycologists, bioprocess engineers, chemical engineers, scientists, and researchers in the water, food, pharmaceutical, and renewable energy industries will find this book beneficial. Likewise, students and faculty in the chemical engineering and energy departments will gain valuable knowledge from its contents.

Download or read book Sustainable Production of Bulk Chemicals written by Mo Xian and published by Springer. This book was released on 2015-11-17 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes in detail the authors’ current understanding of the models that incorporate the concepts and techniques of synthetic chemistry, chemical engineering, synthetic biology and bioengineering. These include chemical engineering methods for green chemical production from sustainable bio-resources; using synthetic chemistry and kinetics of chemical reaction concepts in the construction of non-natural enzymes and bio-pathways, partial integration of bioconversion steps in chemical synthesis routes; integration of chemo-, bio- conversion steps in one system; microbial production of chemicals from economic chemo-resourced chemicals; and chemical production of value-added derivatives from bio-based amino acids. It provides a valuable reference source for laboratory and industrial professionals in a number of chemical and biological disciplines such as synthetic chemistry, synthetic biology, chemical engineering, biotechnology, microbiology, molecular biology, etc. Dr. Mo Xian is a Professor at Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China.

Download or read book Microbial Cell Factories Engineering for Production of Biomolecules written by Vijai Singh and published by Academic Press. This book was released on 2021-02-13 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Cell Factories Engineering for Production of Biomolecules presents a compilation of chapters written by eminent scientists worldwide. Sections cover major tools and technologies for DNA synthesis, design of biosynthetic pathways, synthetic biology tools, biosensors, cell-free systems, computer-aided design, OMICS tools, CRISPR/Cas systems, and many more. Although it is not easy to find relevant information collated in a single volume, the book covers the production of a wide range of biomolecules from several MCFs, including Escherichia coli, Bacillus subtilis, Pseudomonas putida, Streptomyces, Corynebacterium, Cyanobacteria, Saccharomyces cerevisiae, Pichia pastoris and Yarrowia lipolytica, and algae, among many others. This will be an excellent platform from which scientific knowledge can grow and widen in MCF engineering research for the production of biomolecules. Needless to say, the book is a valuable source of information not only for researchers designing cell factories, but also for students, metabolic engineers, synthetic biologists, genome engineers, industrialists, stakeholders and policymakers interested in harnessing the potential of MCFs in several fields. Offers basic understanding and a clear picture of various MCFs Explains several tools and technologies, including DNA synthesis, synthetic biology tools, genome editing, biosensors, computer-aided design, and OMICS tools, among others Harnesses the potential of engineered MCFs to produce a wide range of biomolecules for industrial, therapeutic, pharmaceutical, nutraceutical and biotechnological applications Highlights the advances, challenges, and future opportunities in designing MCFs

Download or read book Synthetic Biology written by Markus Schmidt and published by John Wiley & Sons. This book was released on 2012-05-14 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the only book to focus on industrial and environmental applications of synthetic biology, covering 17 of the most promising uses in the areas of biofuel, bioremediation and biomaterials. The contributions are written by experts from academia, non-profit organizations and industry, outlining not only the scientific basics but also the economic, environmental and ethical impact of the new technologies. This makes it not only suitable as supplementary material for students but also the perfect companion for policy makers and funding agencies, if they are to make informed decisions about synthetic biology. Largely coordinated by Markus Schmidt, a policy adviser, and the only European to testify in front of the bioethics commission of the Obama administration.