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Book Small Molecule DNA and RNA Binders

Download or read book Small Molecule DNA and RNA Binders written by Martine Demeunynck and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of molecules that selectively bind to nucleic acids has provided many details about DNA and RNA recognition. The range of such substances, such as metal complexes, peptides, oligonucleotides and a wide array of synthetic organic compounds, is as manifold as the functions of nucleic acids. Nucleic acid recognition sequences are often found in the major or minor groove of a double strand, while other typical interactions include intercalation between base pairs or the formation of triple or quadruple helices. One example of a binding mode that has recently been proposed is end stacking on such complex structures as the telomere tetraplex. In this comprehensive book, internationally recognized experts describe in detail the important aspects of nucleic acid binding, and in so doing present impressive approaches to drug design. Since typical substances may be created naturally or synthetically, emphasis is placed on natural products, chemical synthesis, the use of combinatorial libraries, and structural characterization. The whole is rounded off by contributions on molecular modeling, as well as investigations into the way in which any given drug interacts with its nucleic acid recognition site.

Book Synthesis and Characterization of Nickel II  Complexes of a Hydrotrispyrazolylborate Ligand and of Novel Phosphinetrithiol Ligands

Download or read book Synthesis and Characterization of Nickel II Complexes of a Hydrotrispyrazolylborate Ligand and of Novel Phosphinetrithiol Ligands written by Weihong Zhang and published by . This book was released on 1990 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Synthesis and Characterization of Nickel II  Complexes of a Hydrotrispyrazolylborato Ligand and of the Thiosalicylato Ligand

Download or read book Synthesis and Characterization of Nickel II Complexes of a Hydrotrispyrazolylborato Ligand and of the Thiosalicylato Ligand written by Weibin Chen and published by . This book was released on 1994 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Synthesis and Characterization of Nickel II  Compounds with Sulfur Donor Ligands

Download or read book Synthesis and Characterization of Nickel II Compounds with Sulfur Donor Ligands written by Li Zhou and published by . This book was released on 1995 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Synthesis and Characterization of Mixed Donor Ligands and Their Corresponding Metal Complexes

Download or read book Synthesis and Characterization of Mixed Donor Ligands and Their Corresponding Metal Complexes written by Timothy Michael Erasmus Jugovic and published by . This book was released on 2017 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presented in this thesis is the synthesis and characterization of two new classes of mixed donor ligands, as well as several copper(II) and nickel(II) complexes. Chapter II details the synthesis and characterization of thiosemicarbazates, which are tridentate ONS (oxygen, nitrogen, sulfur) donor compounds. In Chapter III complexes of these thiosemicarbazate ligands with nickel(II) and copper(II) are prepared and characterized. Chapter IV discusses the synthesis and characterization of several different amidothiocrown and amidoazathiocrown ethers.

Book Synthesis and Characterization of Nickel and Copper Complexes of Oxazolidine Ligands

Download or read book Synthesis and Characterization of Nickel and Copper Complexes of Oxazolidine Ligands written by Joseph L. Hedrick and published by . This book was released on 1990 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The synthesis and characterization of three novel ligands containing oxazolidine moieties has been performed. The synthesis of Cu2 complexes of the ligands were found to be straightforward yielding the desired product. Syntheses of the Ni2 complexes were not straight forward. Only one of the Ni2+ complexes could be isolated in a pure form. A partial hydrolysis product of another of the Ni-ligand complexes could be isolated."--Abstract.

Book Synthesis and Characterization of Binucleating Ligands and Their Manganese Complexes as Models for the Oxidation of Water to Moleculat Oxygen

Download or read book Synthesis and Characterization of Binucleating Ligands and Their Manganese Complexes as Models for the Oxidation of Water to Moleculat Oxygen written by Habibe Diril and published by . This book was released on 1988 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Synthesis and Reactivity of Water soluble N donor Ligand Metal Complexes  Capable of Promoting the Hydrolysis of Organophosphorous Substrates

Download or read book Synthesis and Reactivity of Water soluble N donor Ligand Metal Complexes Capable of Promoting the Hydrolysis of Organophosphorous Substrates written by Navdeep Kaur Bilon and published by . This book was released on 2009 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Synthesis and Characterization of Novel Organic Ligands with Their Complexes of Platinum  Copper and Uranium

Download or read book Synthesis and Characterization of Novel Organic Ligands with Their Complexes of Platinum Copper and Uranium written by Mustafa Adnan Yasin Aldulaimi and published by . This book was released on 2021 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: