Download or read book Survival Analysis for Epidemiologic and Medical Research written by Steve Selvin and published by Cambridge University Press. This book was released on 2008-03-03 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide to survival data and its analysis for readers with a minimal background in statistics shows why the analytic methods work and how to effectively analyze and interpret epidemiologic and medical survival data with the help of modern computer systems. The introduction presents a review of a variety of statistical methods that are not only key elements of survival analysis but are also central to statistical analysis in general. Techniques such as statistical tests, transformations, confidence intervals, and analytic modeling are presented in the context of survival data but are, in fact, statistical tools that apply to understanding the analysis of many kinds of data. Similarly, discussions of such statistical concepts as bias, confounding, independence, and interaction are presented in the context of survival analysis and also are basic components of a broad range of applications. These topics make up essentially a 'second-year', one-semester biostatistics course in survival analysis concepts and techniques for non-statisticians.
Download or read book Survival Analysis written by David G. Kleinbaum and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: A straightforward and easy-to-follow introduction to the main concepts and techniques of the subject. It is based on numerous courses given by the author to students and researchers in the health sciences and is written with such readers in mind. A "user-friendly" layout includes numerous illustrations and exercises and the book is written in such a way so as to enable readers learn directly without the assistance of a classroom instructor. Throughout, there is an emphasis on presenting each new topic backed by real examples of a survival analysis investigation, followed up with thorough analyses of real data sets. Each chapter concludes with practice exercises to help readers reinforce their understanding of the concepts covered, before going on to a more comprehensive test. Answers to both are included. Readers will enjoy David Kleinbaums style of presentation, making this an excellent introduction for all those coming to the subject for the first time.
Download or read book Modelling Survival Data in Medical Research written by D. Collett and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Fourth edition has new chapters on Bayesian survival analysis and use of the R software. Chapters extensively revised, expanded to add new material on topics that include methods for assessing predictive ability of a model, joint models for longitudinal and survival data, modern methods for the analysis of interval-censored survival data"--
Download or read book Applied Survival Analysis written by David W. Hosmer, Jr. and published by John Wiley & Sons. This book was released on 2011-09-23 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING TIME-TO-EVENT DATA—NOW IN A VALUABLE NEW EDITION Since publication of the first edition nearly a decade ago, analyses using time-to-event methods have increase considerably in all areas of scientific inquiry mainly as a result of model-building methods available in modern statistical software packages. However, there has been minimal coverage in the available literature to9 guide researchers, practitioners, and students who wish to apply these methods to health-related areas of study. Applied Survival Analysis, Second Edition provides a comprehensive and up-to-date introduction to regression modeling for time-to-event data in medical, epidemiological, biostatistical, and other health-related research. This book places a unique emphasis on the practical and contemporary applications of regression modeling rather than the mathematical theory. It offers a clear and accessible presentation of modern modeling techniques supplemented with real-world examples and case studies. Key topics covered include: variable selection, identification of the scale of continuous covariates, the role of interactions in the model, assessment of fit and model assumptions, regression diagnostics, recurrent event models, frailty models, additive models, competing risk models, and missing data. Features of the Second Edition include: Expanded coverage of interactions and the covariate-adjusted survival functions The use of the Worchester Heart Attack Study as the main modeling data set for illustrating discussed concepts and techniques New discussion of variable selection with multivariable fractional polynomials Further exploration of time-varying covariates, complex with examples Additional treatment of the exponential, Weibull, and log-logistic parametric regression models Increased emphasis on interpreting and using results as well as utilizing multiple imputation methods to analyze data with missing values New examples and exercises at the end of each chapter Analyses throughout the text are performed using Stata® Version 9, and an accompanying FTP site contains the data sets used in the book. Applied Survival Analysis, Second Edition is an ideal book for graduate-level courses in biostatistics, statistics, and epidemiologic methods. It also serves as a valuable reference for practitioners and researchers in any health-related field or for professionals in insurance and government.
Download or read book Survival Analysis for Epidemiologic and Medical Research written by S. Selvin and published by . This book was released on 2008 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: For readers with a minimal background in statistics, this text shows how to analyze and interpret epidemiological and medical survival data.
Download or read book Epidemiology and Medical Statistics written by and published by Elsevier. This book was released on 2007-11-21 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, representing a compilation of authoritative reviews on a multitude of uses of statistics in epidemiology and medical statistics written by internationally renowned experts, is addressed to statisticians working in biomedical and epidemiological fields who use statistical and quantitative methods in their work. While the use of statistics in these fields has a long and rich history, explosive growth of science in general and clinical and epidemiological sciences in particular have gone through a see of change, spawning the development of new methods and innovative adaptations of standard methods. Since the literature is highly scattered, the Editors have undertaken this humble exercise to document a representative collection of topics of broad interest to diverse users. The volume spans a cross section of standard topics oriented toward users in the current evolving field, as well as special topics in much need which have more recent origins. This volume was prepared especially keeping the applied statisticians in mind, emphasizing applications-oriented methods and techniques, including references to appropriate software when relevant.· Contributors are internationally renowned experts in their respective areas· Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research· Methods for assessing Biomarkers, analysis of competing risks· Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs· Structural equations modelling and longitudinal data analysis
Download or read book Applied Survival Analysis Using R written by Dirk F. Moore and published by Springer. This book was released on 2016-05-11 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applied Survival Analysis Using R covers the main principles of survival analysis, gives examples of how it is applied, and teaches how to put those principles to use to analyze data using R as a vehicle. Survival data, where the primary outcome is time to a specific event, arise in many areas of biomedical research, including clinical trials, epidemiological studies, and studies of animals. Many survival methods are extensions of techniques used in linear regression and categorical data, while other aspects of this field are unique to survival data. This text employs numerous actual examples to illustrate survival curve estimation, comparison of survivals of different groups, proper accounting for censoring and truncation, model variable selection, and residual analysis. Because explaining survival analysis requires more advanced mathematics than many other statistical topics, this book is organized with basic concepts and most frequently used procedures covered in earlier chapters, with more advanced topics near the end and in the appendices. A background in basic linear regression and categorical data analysis, as well as a basic knowledge of calculus and the R system, will help the reader to fully appreciate the information presented. Examples are simple and straightforward while still illustrating key points, shedding light on the application of survival analysis in a way that is useful for graduate students, researchers, and practitioners in biostatistics.
Download or read book Survival Analysis for Epidemiologic and Medical Research written by Steve Selvin and published by Cambridge University Press. This book was released on 2008-03-03 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide shows why the analytic methods work and how to effectively analyze and interpret epidemiologic and medical survival data with the help of modern computer systems. The introduction presents a review of a variety of statistical methods that are not only key elements of survival analysis but are also central to statistical analysis in general. Techniques such as statistical tests, transformations, confidence intervals, and analytic modeling are presented in the context of survival data but are, in fact, statistical tools that apply to understanding the analysis of many kinds of data. Similarly, discussions of such statistical concepts such as bias, confounding, independence, and interaction are presented in the context of survival analysis as well as the basic components of a broad range of applications.
Download or read book Analysis of Cancer Risks in Populations Near Nuclear Facilities written by National Research Council and published by National Academies Press. This book was released on 2012-06-29 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.
Download or read book Statistical Analysis of Epidemiologic Data written by S. Selvin and published by Oxford University Press, USA. This book was released on 1996 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book combines applied and theoretical approaches to the analysis of epidemiologic issues. It goes beyond elementary material to deal with real problems generated by disease data, and delves into less usual areas such as the analysis of spatial distributions, survival data, proportional hazards regression, and "computer-intensive" approaches to statistical estimation. Each method discussed in the text is illustrated with examples which include complete sets of data. Using actual data demonstrates the strengths and weaknesses of different analytic approaches in describing a disease process. The goal of the book is to allow the reader to develop a clear understanding of analytic approaches to problems in epidemiologic data analysis without relying on sophisticated mathematics and advanced statistical theory. For the Second Edition a new chapter on the analysis of matched data has been added. This covers both discrete and continuous outcomes and explains both the classic analytic approach and the conditional logistic regression model. New sections have also been added on contingency table data, misclassification, and additive models underlying tabular data. In all the chapters there are new applications and other revisions that make this Second Edition a clearer and more helpful exposition of the way statistical tools are used to analyze epidemiologic data.
Download or read book Survival Analysis Using SAS written by Paul D. Allison and published by SAS Institute. This book was released on 2010-03-29 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Easy to read and comprehensive, Survival Analysis Using SAS: A Practical Guide, Second Edition, by Paul D. Allison, is an accessible, data-based introduction to methods of survival analysis. Researchers who want to analyze survival data with SAS will find just what they need with this fully updated new edition that incorporates the many enhancements in SAS procedures for survival analysis in SAS 9. Although the book assumes only a minimal knowledge of SAS, more experienced users will learn new techniques of data input and manipulation. Numerous examples of SAS code and output make this an eminently practical book, ensuring that even the uninitiated become sophisticated users of survival analysis. The main topics presented include censoring, survival curves, Kaplan-Meier estimation, accelerated failure time models, Cox regression models, and discrete-time analysis. Also included are topics not usually covered in survival analysis books, such as time-dependent covariates, competing risks, and repeated events. Survival Analysis Using SAS: A Practical Guide, Second Edition, has been thoroughly updated for SAS 9, and all figures are presented using ODS Graphics. This new edition also documents major enhancements to the STRATA statement in the LIFETEST procedure; includes a section on the PROBPLOT command, which offers graphical methods to evaluate the fit of each parametric regression model; introduces the new BAYES statement for both parametric and Cox models, which allows the user to do a Bayesian analysis using MCMC methods; demonstrates the use of the counting process syntax as an alternative method for handling time-dependent covariates; contains a section on cumulative incidence functions; and describes the use of the new GLIMMIX procedure to estimate random-effects models for discrete-time data. This book is part of the SAS Press program.
Download or read book Epidemiology and Biostatistics written by Bryan Kestenbaum and published by Springer Science & Business Media. This book was released on 2009-08-28 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concise, fast-paced, intensive introduction to clinical research design for students and clinical research professionals Readers will gain sufficient knowledge to pass the United States Medical Licensing Examination part I section in Epidemiology
Download or read book Epidemiology written by Mark Woodward and published by CRC Press. This book was released on 2013-12-19 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highly praised for its broad, practical coverage, the second edition of this popular text incorporated the major statistical models and issues relevant to epidemiological studies. Epidemiology: Study Design and Data Analysis, Third Edition continues to focus on the quantitative aspects of epidemiological research. Updated and expanded, this edition shows students how statistical principles and techniques can help solve epidemiological problems. New to the Third Edition New chapter on risk scores and clinical decision rules New chapter on computer-intensive methods, including the bootstrap, permutation tests, and missing value imputation New sections on binomial regression models, competing risk, information criteria, propensity scoring, and splines Many more exercises and examples using both Stata and SAS More than 60 new figures After introducing study design and reviewing all the standard methods, this self-contained book takes students through analytical methods for both general and specific epidemiological study designs, including cohort, case-control, and intervention studies. In addition to classical methods, it now covers modern methods that exploit the enormous power of contemporary computers. The book also addresses the problem of determining the appropriate size for a study, discusses statistical modeling in epidemiology, covers methods for comparing and summarizing the evidence from several studies, and explains how to use statistical models in risk forecasting and assessing new biomarkers. The author illustrates the techniques with numerous real-world examples and interprets results in a practical way. He also includes an extensive list of references for further reading along with exercises to reinforce understanding. Web Resource A wealth of supporting material can be downloaded from the book’s CRC Press web page, including: Real-life data sets used in the text SAS and Stata programs used for examples in the text SAS and Stata programs for special techniques covered Sample size spreadsheet
Download or read book Biostatistics for Epidemiology and Public Health Using R written by Bertram K.C. Chan, PhD and published by Springer Publishing Company. This book was released on 2015-11-05 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since it first appeared in 1996, the open-source programming language R has become increasingly popular as an environment for statistical analysis and graphical output. In addition to being freely available, R offers several advantages for biostatistics, including strong graphics capabilities, the ability to write customized functions, and its extensibility. This is the first textbook to present classical biostatistical analysis for epidemiology and related public health sciences to students using the R language. Based on the assumption that readers have minimal familiarity with statistical concepts, the author uses a step-bystep approach to building skills. The text encompasses biostatistics from basic descriptive and quantitative statistics to survival analysis and missing data analysis in epidemiology. Illustrative examples, including real-life research problems and exercises drawn from such areas as nutrition, environmental health, and behavioral health, engage students and reinforce the understanding of R. These examples illustrate the replication of R for biostatistical calculations and graphical display of results. The text covers both essential and advanced techniques and applications in biostatistics that are relevant to epidemiology. This text is supplemented with teaching resources, including an online guide for students in solving exercises and an instructor's manual. KEY FEATURES: First overview biostatistics textbook for epidemiology and public health that uses the open-source R program Covers essential and advanced techniques and applications in biostatistics as relevant to epidemiology Features abundant examples and exercises to illustrate the application of R language for biostatistical calculations and graphical displays of results Includes online student solutions guide and instructor's manual
Download or read book Standards for Pediatric Immunization Practice written by and published by . This book was released on 1993 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biostatistics and Computer based Analysis of Health Data using Stata written by Christophe Lalanne and published by Elsevier. This book was released on 2016-09-06 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the Biostatistics and Health Sciences Set focuses on statistics applied to clinical research. The use of Stata for data management and statistical modeling is illustrated using various examples. Many aspects of data processing and statistical analysis of cross-sectional and experimental medical data are covered, including regression models commonly found in medical statistics. This practical book is primarily intended for health researchers with basic knowledge of statistical methodology. Assuming basic concepts, the authors focus on the practice of biostatistical methods essential to clinical research, epidemiology and analysis of biomedical data (including comparison of two groups, analysis of categorical data, ANOVA, linear and logistic regression, and survival analysis). The use of examples from clinical trials and epideomological studies provide the basis for a series of practical exercises, which provide instruction and familiarize the reader with essential Stata packages and commands. - Provides detailed examples of the use of Stata for common biostatistical tasks in medical research - Features a work program structured around the four previous chapters and a series of practical exercises with commented corrections - Includes an appendix to help the reader familiarize themselves with additional packages and commands - Focuses on the practice of biostatistical methods that are essential to clinical research, epidemiology, and analysis of biomedical data
Download or read book Developing a Protocol for Observational Comparative Effectiveness Research A User s Guide written by Agency for Health Care Research and Quality (U.S.) and published by Government Printing Office. This book was released on 2013-02-21 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: This User’s Guide is a resource for investigators and stakeholders who develop and review observational comparative effectiveness research protocols. It explains how to (1) identify key considerations and best practices for research design; (2) build a protocol based on these standards and best practices; and (3) judge the adequacy and completeness of a protocol. Eleven chapters cover all aspects of research design, including: developing study objectives, defining and refining study questions, addressing the heterogeneity of treatment effect, characterizing exposure, selecting a comparator, defining and measuring outcomes, and identifying optimal data sources. Checklists of guidance and key considerations for protocols are provided at the end of each chapter. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews. More more information, please consult the Agency website: www.effectivehealthcare.ahrq.gov)
