Download or read book Surface Modification of Titanium Using Anodization to Enhance Antimicrobial Properties and Osseointegration written by Sakshi Jain and published by . This book was released on 2017 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Titanium and its alloys are frequently used in dental and orthopedic implants because they have good mechanical strength, chemical stability and biocompatibility. These properties can be further improved by surface treatments such as anodization that are able to grow thicker and produce crystalline oxide layers with controlled morphological and physico-chemical properties. Both anatase (A) and rutile (R) crystalline phases of titanium oxide have been shown to promote bioactivity and antimicrobial effects. In a previous study in our laboratories, four electrolyte mixtures were optimized to produce anodized layers on commercially pure titanium consisting of specific anatase and rutile oxide ratios at an endpoint forming voltage of 180 V. In the present study, changes that occurred in the anodized layers with increasing forming voltage including crystallinity, thickness, surface morphology, surface roughness, surface chemistry, fractal dimension, shear strength, and corrosion resistance were determined for each of these electrolytes. The results showed the crystallinity, thickness, surface pore sizes, and surface roughness increased with increasing forming voltage. Incorporation of phosphorus into the anodized layers was shown in phosphoric acid containing electrolytes at higher forming voltages. Decreases in corrosion resistance were also shown at higher forming voltages in each electrolyte due to increased pore interconnectivity within the anodized layers. In addition, the apatite inducing ability of anodized layers in SBF was examined for selected forming voltages in each electrolyte. Anodization in phosphoric acid containing electrolytes was shown to be more favorable for apatite formation. The streptococcal and MRSA bacterial attachment before and after UV treatments was determined for selected forming voltages in each electrolyte. Additionally, the killing efficacy after 10-minute pre-irradiation with UVA or UVC treatments was determined. UVA treatments showed trends of at least a 20% reduction in bacterial attachment regardless of the crystallinity within the oxide for S. sanguinis. The anodized layer with an approximately equal distribution of anatase and rutile phases showed bacterial killing efficacy over 50% for S. sanguinis and over 80% for MRSA after UVA or UVC treatments. Finally, two forming voltage sample groups in two of the electrolytes were examined for MC3T3E-1 cell attachment, proliferation, and differentiation. Total intracellular protein content, alkaline phosphatase (ALP) activity, osteocalcin (OCN) activity, and cellular mineralization were investigated for different time periods up to 21 days. All sample groups showed suitable cellular proliferation, differentiation, and maturation but those anodized in the phosphoric acid containing electrolyte showed delayed proliferation and early differentiation and maturation. Also, anodized samples containing at least 50% anatase were shown to produce higher osteoblast mineralization compared to majority rutile phase anodized layers.
Download or read book Surface Modification Strategies for Antimicrobial Titanium Implant Materials with Enhanced Osseointegration written by Kennedy Omoniala and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Surface Modification of Titanium Dental Implants written by Karan Gulati and published by Springer Nature. This book was released on 2023-02-27 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive technical and scientific overview of the surface modification of titanium dental implants. Coverage ranges from basic concepts of surface modification to advanced micro- and nano-engineering strategies employed to achieve augmented bioactivity to meet the needs of compromised patient conditions. A special focus of the book is advanced state-of-the-art electrochemically anodized nanostructures fabricated on implants towards enhanced bioactivity and local therapy. Surface Modification of Titanium Dental Implants will keep you current in the domain of titanium dental implants and will provide an improved understanding of their performance and application. The book will benefit engineers, clinicians, and researchers in biomaterials, biomedical engineering, dental and bone implants, nano-engineering, and technology.
Download or read book Surface Modification of Bio implantable Ti 6Al 4V Alloy for Enhanced Osseointegration and Antibacterial Capability written by Ziyuan Wang and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface-induced osseointegration and antibacterial capability are very important criteria for the clinical success of titanium implants. To enhance these two criteria, an architectural hybrid system is constructed onto Ti-6Al-4V with a rough surface. First, thermal oxidation (TO), treatment with hydrogen peroxide (H2O2) and a mix of TO and H2O2 (Mixed) are used to modify the surface topography and chemistry of Ti-6Al-4V disks. Surface characterizations by the use of microscopes and spectroscopes indicate that TO can induce more favorable topography, roughness, wettability and hydroxyl group concentration on Ti-6Al-4V surfaces. Therefore, an alginate/chitosan LBL film that incorporates antibacterial nano-silver is bridged onto thermally oxidized Ti-6Al-4V alloy by mussel-inspired dopamine. The microscopies and spectrometers confirm that the hybrid system is successfully fabricated onto the Ti-6Al-4V surface while the sub-micron topography induced by TO is maintained. Bone marrow stem cell (BMSC) adhesion, proliferation and differentiation are up-regulated by the synergy of sub-micron surface produced by TO and alginate/chitosan LBL film. The incorporation of nano-silver into the hybrid system is demonstrated to inhibit the growth of Escherichia coli and Staphylococcus aureus, but not jeopardize the enhanced BMSC activities. Taken together, this thesis presents a promising strategy to fabricate novel Ti-6Al-4V implants with enhanced osseointegration and antibacterial capability.
Download or read book Surface Modification of Titanium for Biomaterial Applications written by Kyo-Han Kim and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book starts with concepts of bone, its structure, remodelling, materials for implants and implant testing methods. Calcium phosphate ceramics and need for titanium surface modification are detailed in the initial chapters. Surface modification techniques include plasma spraying, sol-gel, biomimetic, electrochemical, laser, sputtering and ion-implantation methods. Chapters 5 to 19 deal with these modification techniques. Chapters 20-22 deal with less-common methods titanium nitride coating, protein modification, diamond like carbon coating and ultraviolet treatment. Substituting the apatite lattice with other cations like silicon, magnesium, sodium, carbon, etc is provided. The chapters involving these techniques begin with a small introduction about that technique and go on to explain the underlying principles, methodology and properties of the coats. According to the authors, the book gives a complete overview of almost all the surface modification techniques known, as applied to titanium biomaterials.
Download or read book Implementation of Titanium Anodization to Produce an Anatase Surface Layer written by Randall Scott Williamson and published by . This book was released on 2013 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book TiO2 Nanotubes on Titanium for Early Stage Osseointegration written by Anish Shivaram and published by . This book was released on 2017 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The results show mechanically stable TiO2 nanotubes up to 1microm length used on titanium surface were successful in improving the early stage osseointegrative properties. The use of silver coatings can provide a solution for infection control in vivo. The use of dopants and surface charge further helped enhancing the surface properties of TiO 2 nanotubes which would further enhance the early stage osseointegrative properties.
Download or read book Nano Enhanced Surface Modification of Titanium Dental Implants for Improving Osseointegration and Biocompatibility written by Ranj Salaie and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tissue integrated Prostheses written by Per-Ingvar Brånemark and published by Quintessence Publishing (IL). This book was released on 1985 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: " This book provides the prosthodontist and oral surgeon for the first time with a safe, predictable, and scientifically proven method for permanently anchoring artificial tooth abutments in the jawbones. It combines the osseointegration research results of biologists, physicists, bioengineers, oral surgeons, and prosthodontists to demonstrate step-by-step how to achieve long-term osseointegration of dental implants" -- Amazon.
Download or read book Surface Modification of Titanium and Titanium Alloys to Enhance Bone Healing written by Yasmeen Janzeer and published by . This book was released on 2013 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomaterials Science Processing Properties and Applications V written by Roger Narayan and published by John Wiley & Sons. This book was released on 2015-10-05 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking place at the David L. Lawrence Convention Center, Pittsburgh, Pennsylvania, this CT Volume contains 17 papers from the following 2014 Materials Science and Technology (MS&T'14) symposia: Next Generation Biomaterials Surface Properties of Biomaterials
Download or read book The Effects of Surface Modification on the Osseointegration of Titanium Dental Implants written by John Samuel Lawrence Colombo and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Processing Microstructure Characterization and Biological Performance of Hierarchical Surface Coatings for Titanium Implants written by Ellen Elizabeth Sauter and published by . This book was released on 2013 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently, the lifetime of a typical orthopaedic implant is only 15-20 years, a lifetime that many patients are outliving. Therefore, implants with superior longevity need to be engineered. To improve implant longevity, much research has been focused on creating micro-scale porosity/roughness to enhance osseointegration by mechanical interlocking of bone and implant. These structures have improved osseointegration to the current 15-20 year lifespan. It has also been shown that nano-scale structures enhance osteoblast (bone cell) function. The combination of micro-scale and nano-scale structures into one hierarchical structure may further improve the osseointegrative properties of implants. A hierarchical surface modification consisting of titanium dioxide [(TiO2)] nanotubes produced by anodic oxidation of titanium in an electrolyte containing fluoride ions, [F], on a commercially pure (cp) titanium, micro-scale grid structure produced by laser powder deposition was successfully developed. [TiO2] nanotubes were characterized using field emission scanning electron microscopy (FE-SEM), while laser deposited grid structures were characterized with both FE-SEM and optical microscopy. Mouse preosteoblasts were used to evaluate the in vitro biological effects, including cell morphology and cell viability, on the four experimental groups: unanodized flat, anodized flat, unanodized laser deposition, and anodized laser deposition. All treatment groups showed good cell attachment and spreading; however, it was observed that on the samples with [TiO2] nanotubes there was a much greater density of adhesion proteins. The presence of these proteins provides a surface that cells can more readily attach to which can lead to greater cell proliferation and differentiation. Also, viability of cells on samples with nanotubes was higher than samples without nanotubes. However, viability was highest on the anodized flat surface, suggesting that the micro-scale grid on the surface of laser deposition samples did not positively affect the osteoblasts. Optimization of the micro-scale surface features, along with anodization of the micro-scale structures, could possibly further improve the bone/implant interaction and further study is needed on this topic.
Download or read book Surface Modification of Titanium for Hard tissue Engineering Applications written by Murali Krishna Duvvuru and published by . This book was released on 2018 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: Titanium (Ti) and its alloys are widely used in dental and orthopedic applications due to their advantages such as biocompatibility, excellent corrosion resistance and mechanical properties like low Young's modulus, low density and high strength as compared to other metallic implants. However, lack of interaction with host tissue (e.g. bioinertness), higher modulus of elasticity as compared to that of bone and resultant stress shielding cause fibrous tissue formation around the implant where the interaction with tissue is minimized. These will eventually cause the implant loosening and revision surgery is needed. Surface modification of Ti by increasing surface roughness and/or incorporation of trace elements where cellular interaction is improved, is a promising technique to enhance the bioactivity. Surface modification can be achieved through alkali treatment, acidic treatment, sol-gel, and electrochemical anodization. Among these techniques, anodization has received significant attention as it allows formation of uniform titanium nanotubes throughout the material. Although this method is simple, low cost and controllable, modification of complicated geometries by this method is a concern. On the other hand, alkali treatment method is available to increase the surface roughness of metals with various geometries by formation of porous network structure. To further increase the bioactivity of biomaterial and enhance the osteointegration, incorporation of trace elements such as strontium (Sr), magnesium (Mg), silver (Ag) and iron (Fe) is beneficial. The objective of this research is to optimize the anodization and alkali treatment techniques, along with Fe deposition using physical vapor deposition (PVD) method. Different anodization conditions, alkali concentrations and Fe coating thicknesses were selected and their effects on surface morphology was studied. Finally, the effects of surface modification alone or in combination with Fe deposition on bone cell interaction will be investigated.
Download or read book Titanium written by Matthew J. Donachie and published by ASM International. This book was released on 2000 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to support the need of engineering, management, and other professionals for information on titanium by providing an overview of the major topics, this book provides a concise summary of the most useful information required to understand titanium and its alloys. The author provides a review of the significant features of the metallurgy and application of titanium and its alloys. All technical aspects of the use of titanium are covered, with sufficient metals property data for most users. Because of its unique density, corrosion resistance, and relative strength advantages over competing materials such as aluminum, steels, and superalloys, titanium has found a niche in many industries. Much of this use has occurred through military research, and subsequent applications in aircraft, of gas turbine engines, although more recent use features replacement joints, golf clubs, and bicycles.Contents include: A primer on titanium and its alloys, Introduction to selection of titanium alloys, Understanding titanium's metallurgy and mill products, Forging and forming, Castings, Powder metallurgy, Heat treating, Joining technology and practice, Machining, Cleaning and finishing, Structure/processing/property relationships, Corrosion resistance, Advanced alloys and future directions, Appendices: Summary table of titanium alloys, Titanium alloy datasheets, Cross-reference to titanium alloys, Listing of selected specification and standardization organizations, Selected manufacturers, suppliers, services, Corrosion data, Machining data.
Download or read book Titanium in Medical and Dental Applications written by Francis Froes and published by Woodhead Publishing. This book was released on 2018-05-09 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Titanium in Medical and Dental Applications is an essential reference book for those involved in biomedical materials and advanced metals. Written by well-known experts in the field, it covers a broad array of titanium uses, including implants, instruments, devices, the manufacturing processes used to create them, their properties, corrosion resistance and various fabrication approaches. Biomedical titanium materials are a critically important part of biomaterials, especially in cases where non-metallic biomedical materials are not suited to applications, such as the case of load-bearing implants. The book also covers the use of titanium for implants in the medical and dental fields and reviews the use of titanium for medical instruments and devices. Provides an understanding of the essential and broad applications of Titanium in both the medical and dental industries Discusses the pathways to manufacturing titanium into critical biomedical and dental devices Includes insights into further applications within the industry
Download or read book Surface Modification to Improve Properties of Materials written by Miran Mozetič and published by MDPI. This book was released on 2019-04-16 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains selected contributions on surface modification to improve the properties of solid materials. The surface properties are tailored either by functionalization, etching, or deposition of a thin coating. Functionalization is achieved by a brief treatment with non-equilibrium gaseous plasma containing suitable radicals that interact chemically with the material surface and thus enable the formation of rather stable functional groups. Etching is performed in order to modify the surface morphology. The etching parameters are selected in such a way that a rich morphology of the surfaces is achieved spontaneously on the sub-micrometer scale, without using masks. The combination of adequate surface morphology and functionalization of materials leads to superior surface properties which are particularly beneficial for the desired response upon incubation with biological matter. Alternatively, the materials are coated with a suitable thin film that is useful in various applications from food to aerospace industries.
