Download or read book Surface Modification for the Enhancement of Osseointegrated Titanium Implants for Dental Application written by Lertrit Sarinnaphakorn and published by . This book was released on 2009 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Surface Modification of Titanium Dental Implants written by Karan Gulati and published by Springer Nature. This book was released on 2023-02-27 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive technical and scientific overview of the surface modification of titanium dental implants. Coverage ranges from basic concepts of surface modification to advanced micro- and nano-engineering strategies employed to achieve augmented bioactivity to meet the needs of compromised patient conditions. A special focus of the book is advanced state-of-the-art electrochemically anodized nanostructures fabricated on implants towards enhanced bioactivity and local therapy. Surface Modification of Titanium Dental Implants will keep you current in the domain of titanium dental implants and will provide an improved understanding of their performance and application. The book will benefit engineers, clinicians, and researchers in biomaterials, biomedical engineering, dental and bone implants, nano-engineering, and technology.

Download or read book Nano Enhanced Surface Modification of Titanium Dental Implants for Improving Osseointegration and Biocompatibility written by Ranj Salaie and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Effects of Surface Modified Titanium Implants on Osseointegration in Irradiated Bone written by Junyuan Li and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Effects of Surface-modified Titanium Implants on Osseointegration in Irradiated Bone" by Junyuan, Li, 黎俊媛, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Radiotherapy is a common treatment for head and neck cancers. However, it compromises bone healing. Titanium implanthas been shown to be a predictable method for replacing missing teeth. Clinical studies revealed that implant failure rate in irradiated regionwas high. Many studies showed that modifications of implant surface could enhance implant osseointegration by improving cell attachment, cell growth and bone formation. Nevertheless, there were few studies investigating the effect of implant surface modification on osseointegration in irradiated bone. In the first experiment, the effect of fluoride-modified (FM) titanium surface on irradiated osteoblast attachment was assessed. The morphology and chemical composition of FM surface was assessed by SEM, AFM and XPS. Osteoblasts received 0Gy, 2Gy, 4Gy, 6Gy, 8Gy, 10Gy radiation. Cell number, fluorescence intensity and cell area of irradiated osteoblasts were assessed. The number of osteoblasts onFM surface was fewer than those on NF surface after 0Gy, 2Gy, 8Gy and 10Gy radiation. Cell area of osteoblasts on FM surface was less at 2Gy radiation but larger at 6Gy radiation than on NF surface. The fluorescence intensity of osteoblasts was also higher on NF surface than on FM surface after receiving 0Gy, 2Gy, 4Gy, 10Gy radiation. In the second experiment, an animal model was established to study the effect of radiation on osseointegration. Rabbits were divided into 15Gy and 30Gy radiation groups. Only the left leg was exposed to radiation, and the right leg was protected from radiation. Totally, 24 implants were inserted. Implant stability quotient (ISQ), bone volume to total volume (BV/TV), bone-to-implant contact (BIC), and bone growth rate were measured. After 15Gy and 30Gy of radiation, ISQ and BV/TV were significantly reduced. At week 3, 15Gy radiation group displayed slower bone growth rate comparing with the control side. Fluorochrome results showed that the 30Gy radiation side had a significantly slower apposition of new bone.In addition, BIC on30Gy radiation side was notablypoorer than that on 15Gy radiation side and on 30Gy control side. Based on the animal model, the third experiment investigated effects of calcium phosphate nanocrystals on implant osseointegration in irradiated bone. Titanium implants treated with nano-scale calcium phosphate (CaP) crystals served as the test group while ones with dual acid-etching only served as the control group. The left leg of rabbits received 15Gy radiation and implants were placed in the irradiated leg. Significant higher ISQ was detected in the nano-CaP group at week 12. The bone growth rate in nano-CaP group was more than doubled than the control group at both week 6 and week 9. The fourth experiment evaluated artifacts on micro-CT images caused by titanium dental implant. Implants were assigned into four groups: (1) implant only; (2) implant with covering screw; (3) implant with resin embedding; and (4) implant with covering screw and resin embedding. Each implant was scanned by micro-CT at 3 angulations. Implant angulation was the most determining factor followed by resin embedding. Minimal metallic artifacts were obtainedin non-embedded implants with its axis paralleling to X-ray. DOI: 10.5353/th_b5312315 Subjects: Osseointegration Dental implants

Download or read book Surface Modification of Titanium Orthodontic Implants written by Abdulqadir Rampurawala and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Orthodontic miniscrews have had a considerable impact on modern orthodontic treatment, not only by providing a new source of anchors for anchorage-demanding cases, but also for force management and control. Whilst miniscrews need to be mechanically stable during treatment to provide sufficient anchorage and predictable force control, as temporary anchorage devices they need also be easy to remove after orthodontic treatment. These requirements differentiate orthodontic miniscrews from dental implants - which once placed, are not to be removed - and dictate the approach as to how their clinical performance can be optimized. Over the past decade, various titanium surface modifications and improvements in implant surface topography have shown to enhance osseointegration of endosseous dental implants. Some of these techniques have helped provide a similar enhancement of the biomechanical potential of orthodontic miniscrews as well. In this perspective, we present a brief discussion on all such reported techniques followed by a detailed account of the most recently proposed ultraviolet photofunctionalization technique - a novel chair-side surface modification method.

Download or read book The Effects of Surface Modification on the Osseointegration of Titanium Dental Implants written by John Samuel Lawrence Colombo and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Surface Modification Strategies for Antimicrobial Titanium Implant Materials with Enhanced Osseointegration written by Kennedy Omoniala and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Surface Modification of Titanium for Biomaterial Applications written by Kyo-Han Kim and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book starts with concepts of bone, its structure, remodelling, materials for implants and implant testing methods. Calcium phosphate ceramics and need for titanium surface modification are detailed in the initial chapters. Surface modification techniques include plasma spraying, sol-gel, biomimetic, electrochemical, laser, sputtering and ion-implantation methods. Chapters 5 to 19 deal with these modification techniques. Chapters 20-22 deal with less-common methods titanium nitride coating, protein modification, diamond like carbon coating and ultraviolet treatment. Substituting the apatite lattice with other cations like silicon, magnesium, sodium, carbon, etc is provided. The chapters involving these techniques begin with a small introduction about that technique and go on to explain the underlying principles, methodology and properties of the coats. According to the authors, the book gives a complete overview of almost all the surface modification techniques known, as applied to titanium biomaterials.

Download or read book Surface Modification of Titanium and Titanium Alloys to Enhance Bone Healing written by Yasmeen Janzeer and published by . This book was released on 2013 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Radiographic Evaluations on the Osseointegration of Photo catalytically Modified Dental Implants in a Murine Model written by Myoe Kyaw Thet and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Osseointegration is defined as: a direct structural and functional connection between ordered, living bone and the surface of a load-carrying implant, without intervening soft tissue, is critical for implant stability and considered a prerequisite for long-term clinical success of endosseous dental implants. Many types of implant surface modification are available nowadays to enhance osseointegration. Light-activated TiO2 surface is one of the surface treatment of titanium. The purpose of the present study was to investigate the effects of the implants, which were coated with the light responsive photocatalytic material, on osseointegration. Maxillary first molars of 6 male C57BL/6NCrSlc mice were extracted bilaterally. Eight weeks after the extraction, two implants were placed in both sides of the maxilla. Photocatalyst implant was placed on the right side (test group) and conventional pure titanium implant was on the left side (control group). After 3, 4 and 6 weeks of implant placement, the animals were sacrificed. The implants and the surrounding tissues were analyzed radiographically. All implants were osseointegrated into bone. But there were no statistically significant differences.

Download or read book Titanium Alloys for Dental and Mixillofacial Applications written by Ros Anita Omar and published by . This book was released on 2011 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Titanium and its alloys are widely used as implant materials for both maxillofacial and orthopaedic application due to their excellent physical and mechanical properties. However, metallic materials lack reactive functional groups and pose a greater challenge for surface modification to enhance bioactivity. Although tissue interactions are dependent on load and implant stability, the surface topology plays a distinct role, hence considerable efforts are being made to modify the surface of titanium implants to enhance osseointegration. -- The current work investigates the biocompatibility of SP700 (Ti-4.5AI3V-2Fe-2Mo) a relatively new alloy of titanium that contains molybdenum and iron, and additionally explores the cytocompatibility of the surfaces obtained post simulating superplastic forming (SPF) of the alloy. Ti64 (TJ-6AI-4V) and SP700 can both be superplastically formed and as manufacturing conditions can alter the properties of a material intended as a medical device, the process should not compromise the clinical conditions or safety. The interaction between the titanium alloys and its investment mould during the SPF process showed changes to the titanium surface properties and the preliminary studies based on in vitro bioactivity testing of the surfaces with the investments Wirovest and Deguvest SR highlighted the existence of an interaction layer between the metal and investment as it was able to form an apatite layer within seven days immersion in simulated body fluid (SBF), which was absent in the non-invested materials. The cytocompatibility of the modified surfaces due to the interaction of the investment and alloy also showed good cell viability and the absence of any toxic leachables. These results show that the interaction of the investment and titanium alloys itself may have potential beneficial effects for hard and soft tissue response following implantation.

Download or read book Surface Modification of Bio implantable Ti 6Al 4V Alloy for Enhanced Osseointegration and Antibacterial Capability written by Ziyuan Wang and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface-induced osseointegration and antibacterial capability are very important criteria for the clinical success of titanium implants. To enhance these two criteria, an architectural hybrid system is constructed onto Ti-6Al-4V with a rough surface. First, thermal oxidation (TO), treatment with hydrogen peroxide (H2O2) and a mix of TO and H2O2 (Mixed) are used to modify the surface topography and chemistry of Ti-6Al-4V disks. Surface characterizations by the use of microscopes and spectroscopes indicate that TO can induce more favorable topography, roughness, wettability and hydroxyl group concentration on Ti-6Al-4V surfaces. Therefore, an alginate/chitosan LBL film that incorporates antibacterial nano-silver is bridged onto thermally oxidized Ti-6Al-4V alloy by mussel-inspired dopamine. The microscopies and spectrometers confirm that the hybrid system is successfully fabricated onto the Ti-6Al-4V surface while the sub-micron topography induced by TO is maintained. Bone marrow stem cell (BMSC) adhesion, proliferation and differentiation are up-regulated by the synergy of sub-micron surface produced by TO and alginate/chitosan LBL film. The incorporation of nano-silver into the hybrid system is demonstrated to inhibit the growth of Escherichia coli and Staphylococcus aureus, but not jeopardize the enhanced BMSC activities. Taken together, this thesis presents a promising strategy to fabricate novel Ti-6Al-4V implants with enhanced osseointegration and antibacterial capability.

Download or read book Tissue integrated Prostheses written by Per-Ingvar Br°anemark and published by . This book was released on 1988 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Bone Response to Dental Implant Materials written by Adriano Piattelli and published by Woodhead Publishing. This book was released on 2016-10-27 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Response to Dental Implant Materials examines the oral environment and the challenges associated with dental biomaterials. Understanding different in vivo and in vitro responses is essential for engineers to successfully design and tailor implant materials which will withstand the different challenges of this unique environment. This comprehensive book reviews the fundamentals of bone responses in a variety of implant materials and presents strategies to tailor and control them. Presents a specific focus on the development and use of biomaterials in the oral environment Discusses the basic science of the dental interface and its clinical applications Contains important coverage on the monitoring and analysis of the dental implant interface

Download or read book Current Concepts in Dental Implantology written by Ilser Turkyilmaz and published by BoD – Books on Demand. This book was released on 2015-02-25 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implant dentistry has changed and enhanced significantly since the introduction of osseointegration concept with dental implants. Because the benefits of therapy became apparent, implant treatment earned a widespread acceptance. Therefore, the need for dental implants has caused a rapid expansion of the market worldwide. Dental implantology continues to excel with the developments of new surgical and prosthodontic techniques, and armamentarium. The purpose of this book named Current Concepts in Dental Implantology is to present a novel resource for dentists who want to replace missing teeth with dental implants. It is a carefully organized book, which blends basic science, clinical experience, and current and future concepts. This book includes ten chapters and our aim is to provide a valuable source for dental students, post-graduate residents and clinicians who want to know more about dental implants.

Download or read book Surface Modification of Titanium Using Anodization to Enhance Antimicrobial Properties and Osseointegration written by Sakshi Jain and published by . This book was released on 2017 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Titanium and its alloys are frequently used in dental and orthopedic implants because they have good mechanical strength, chemical stability and biocompatibility. These properties can be further improved by surface treatments such as anodization that are able to grow thicker and produce crystalline oxide layers with controlled morphological and physico-chemical properties. Both anatase (A) and rutile (R) crystalline phases of titanium oxide have been shown to promote bioactivity and antimicrobial effects. In a previous study in our laboratories, four electrolyte mixtures were optimized to produce anodized layers on commercially pure titanium consisting of specific anatase and rutile oxide ratios at an endpoint forming voltage of 180 V. In the present study, changes that occurred in the anodized layers with increasing forming voltage including crystallinity, thickness, surface morphology, surface roughness, surface chemistry, fractal dimension, shear strength, and corrosion resistance were determined for each of these electrolytes. The results showed the crystallinity, thickness, surface pore sizes, and surface roughness increased with increasing forming voltage. Incorporation of phosphorus into the anodized layers was shown in phosphoric acid containing electrolytes at higher forming voltages. Decreases in corrosion resistance were also shown at higher forming voltages in each electrolyte due to increased pore interconnectivity within the anodized layers. In addition, the apatite inducing ability of anodized layers in SBF was examined for selected forming voltages in each electrolyte. Anodization in phosphoric acid containing electrolytes was shown to be more favorable for apatite formation. The streptococcal and MRSA bacterial attachment before and after UV treatments was determined for selected forming voltages in each electrolyte. Additionally, the killing efficacy after 10-minute pre-irradiation with UVA or UVC treatments was determined. UVA treatments showed trends of at least a 20% reduction in bacterial attachment regardless of the crystallinity within the oxide for S. sanguinis. The anodized layer with an approximately equal distribution of anatase and rutile phases showed bacterial killing efficacy over 50% for S. sanguinis and over 80% for MRSA after UVA or UVC treatments. Finally, two forming voltage sample groups in two of the electrolytes were examined for MC3T3E-1 cell attachment, proliferation, and differentiation. Total intracellular protein content, alkaline phosphatase (ALP) activity, osteocalcin (OCN) activity, and cellular mineralization were investigated for different time periods up to 21 days. All sample groups showed suitable cellular proliferation, differentiation, and maturation but those anodized in the phosphoric acid containing electrolyte showed delayed proliferation and early differentiation and maturation. Also, anodized samples containing at least 50% anatase were shown to produce higher osteoblast mineralization compared to majority rutile phase anodized layers.

Download or read book The Role of Nanostructural and Electrical Surface Properties on the Osteogenic Potential of Titanium Implants written by Rolando Arturo Gittens Ibacache and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Dental and orthopaedic implants are currently the solutions of choice for teeth and joint replacements with success rates continually improving, but they still have undesirable failure rates in patients who are compromised by disease or age, and who in many cases are the ones most in need. The success of titanium (Ti) implants depends on their ability to osseointegrate with the surrounding bone and this, in turn, is greatly dependent on the surface characteristics of the device. Advancements in surface analysis and surface modification techniques have improved the biological performance of metallic implants by mimicking the hierarchical structure of bone associated with regular bone remodeling. In this process, damaged bone is resorbed by osteoclasts, which produce resorption lacunae containing high microroughness generated after mineral dissolution under the ruffled border, as well as superimposed nanoscale features created by the collagen fibers left at the surface. Indeed, increasing Ti surface roughness at the micro and sub-microscale level has been shown to increase osteoblast differentiation in vitro, increase bone-to-implant contact in vivo, and accelerate healing times clinically. Recently, the clinical application of surface nanomodification of implants has been evaluated. Still, most clinically-available devices remain smooth at the nanoscale and fundamental questions remain to be elucidated about the effect of nanoroughness on the initial response of osteoblast lineage cells. \r : Another property that could be used to control osteoblast development and the process of osseointegration is the electrical surface charge of implants. The presence of endogenous electrical signals in bone has been implicated in the processes of bone remodeling and repair. The existence of these native signals has prompted the use of external electrical stimulation to enhance bone growth in cases of fractures with delayed union or nonunion, with several in vitro and in vivo reports confirming its beneficial effects on bone formation. However, the use of electrical stimulation on Ti implants to enhance osseointegration is less understood, in part because of the lack of in vitro models that truly represent the in vivo environment. In addition, an aspect that has not been thoroughly examined is the electrical implication of implant corrosion and its effect on the surrounding tissue. Implants are exposed to extreme conditions in the body such as high pH during inflammation, and cyclic loads. These circumstances may lead to corrosion events that generate large electrochemical currents and potentials, and may cause abnormal cell and tissue responses that could be partly responsible for complications such as aseptic loosening of implants. \r : Consequently, Ti implants with tailored surface characteristics such as nanotopography and electrical polarization, could promote bone healing and osseointegration to ensure successful outcomes for patients by mimicking the biological environment of bone without the use of systemic drugs. The objective of this thesis is to understand how surface nanostructural and electrical characteristics of Ti and Ti alloy surfaces may affect osteoblast lineage cell response in vitro for normal tissue regeneration and repair. Our central hypothesis is that combined micro/nanostructured surfaces, as well as direct stimulation of Ti surfaces with fixed direct current (DC) potentials, can enhance osteoblast differentiation.