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Book Effect of Preirradiation and Postirradiation Erythropoietic Stimulation on Survival Following Exposure to Hematopoietically Lethal X ray Doses

Download or read book Effect of Preirradiation and Postirradiation Erythropoietic Stimulation on Survival Following Exposure to Hematopoietically Lethal X ray Doses written by J. P. Okunewick and published by . This book was released on 1968 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experiments were carried out to evaluate the effect of erythropoietic stimulation on postirradiation survival. A/He and Swiss mice were stimulated to produce red cells at a greater than normal rate through the use of a high altitude chamber. The response to stimulation both before irradiation and after irradiation was examined and compared with that shown by simultaneously irradiated but unstimulated control animals. The mice were maintained at a normal atmosphere for about 3 hours after irradiation in the case of the postirradiation stimulation and for 3 days prior to irradiation in the case of the preirradiation stimulation. The effect of postirradiation stimulation was tested at 700 and 775 R. The poststimulated mice demonstrated poorer survival than the unstimulated controls. These doses were 100 percent lethal at 30 days to both groups, however the mean survival time of the irradiated, stimulated mice was shorter than that of irradiated, unstimulated controls, 4.9 days versus 5.9 days respectively at 775 R, and 5.9 days versus 7.4 days at 700 R. In contrast, mice which were previously erythropoietically stimulated by 3 weeks continuous exposure to one-half atmosphere exhibited a markedly better postirradiation survival than did the unstimulated controls. The effect of preirradiation stimulation was tested at 675 R, 725 R and 775 R. Increased 30- day survival of the prestimulated animals over that of the untreated controls was found at all doses.

Book Nuclear Science Abstracts

Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1974-07 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Nuclear Science Abstracts

Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1970-10 with total page 1028 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Holland Frei Cancer Medicine

Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Book ACRH

    Book Details:
  • Author :
  • Publisher :
  • Release : 1961
  • ISBN :
  • Pages : 158 pages

Download or read book ACRH written by and published by . This book was released on 1961 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Combined Subject and Author Indexes to Radiobiology Bibliographies

Download or read book Combined Subject and Author Indexes to Radiobiology Bibliographies written by U.S. Atomic Energy Commission. Division of Technical Information and published by . This book was released on 1967 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book The Effects of Radiation and Radioisotopes on the Life Processes

Download or read book The Effects of Radiation and Radioisotopes on the Life Processes written by Charles M. Pierce and published by . This book was released on 1963 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book TID

Download or read book TID written by and published by . This book was released on 1966 with total page 908 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Cumulated Index Medicus

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1972 with total page 1354 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Radiation Research

Download or read book Radiation Research written by and published by . This book was released on 1975 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Biological Effects of Ionizing Radiation

Download or read book Biological Effects of Ionizing Radiation written by Marylou Ingram and published by . This book was released on 1966 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Stem Cells

    Book Details:
  • Author : Prasad S. Koka
  • Publisher : Nova Science Publishers
  • Release : 2016
  • ISBN : 9781536102512
  • Pages : 0 pages

Download or read book Stem Cells written by Prasad S. Koka and published by Nova Science Publishers. This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells of varying potencies originating from the organ generating totipotent embryonic stem cells (ESCs) to terminally differented cells such as platelets formation, via pluripotent hematopoietic stem cells (HSCs), and their downstream multipotent mesenchymal stem cells (MSCs), have in general been well characterized. Thus majority of these different stem cell types and their differentiation progeny can be tracked for subjecting to further characterizations for clinical relevance and consequently needed biological modifications at the cellular and molecular levels, for patients clinical treatments. The very first section of this books contents deal with the above stated description. Such characterizations and research laboratory manipulations of the stem cells have led to their clinical grade applications and treatments with positive benefits, as described in the second section of this book. The clinical benefits as published by Nova Science Publishers herein as part of the contents are of tremendous significance and provide relief to the handicapped individuals, particularly for those who suffered lifes biological hazards. This naturally seeks R&D-mediated bench to bedside benefits and solutions for the genetically defective individuals. Bone marrow-derived stem cells with HSCs as their primary components are increasingly being cast the human eyes with pregnant females resorting cord blood banking as they peek to dwell into the future well being of their offspring(s) which could even benefit their own selves, should there be expectedly sufficient HLA matching. The third section of this book deals with such topics. The induced pluripotent stem cells (iPSCs) which were generated to overcome the ethical considerations of using ESCs were fraught with elaborate molecular and cellular biological engineering methods and the advent of derivation and usefulness of MSCs have since sidelined or relegated the iPSCs to a distant role. Nonetheless the hitherto served purpose of iPSCs is not discounted and yet unknown stumbling blocks of what seems to be a smooth going runway of MSCs may spring up in the clinical paths necessitated by the treatment along the future. In the fourth section of the book, it is to be kept in mind that uncontrolled proliferation of cells should be avoided at all costs. Whereas self-renewal of stem cells is generally expected to lead to a turnover, it need not be the case with regeneration processes. This will depend upon the genetic make up of the donor-derived and invasively injected stem cells plus accompanying biological reagent components, as well as also the recipients physical conditions. The fifth and last section of the book deals with conventional and alternative medicine topics applicable to carcinogenesis or such tendencies. Telomerase activity is a double edged sword. Therefore its homeostasis or equilibrium is to be maintained. Discriminatory apoptosis that is of beneficial nature affecting malignant cells but not the normal cells is necessary. Thus equation between apoptotic and telomerase activities even those of stem cells should be as hand in glove.

Book Hemopoietic System

    Book Details:
  • Author : Thomas C. Jones
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 3642841104
  • Pages : 644 pages

Download or read book Hemopoietic System written by Thomas C. Jones and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmon ize toxicologic testing, to advance a more uniform inter pretation of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scien tists. The Monographs on the Pathology of Laboratory Ani mals are designed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others concerned with evaluating toxicity and carcinogen icity studies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our ex pectations that understanding and cooperation will be im proved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on the hemopoietic system, is the eighth volume of a set prepared under the sponsorship of the International Life Sciences In stitute (ILSI).

Book INIS Atomindex

Download or read book INIS Atomindex written by and published by . This book was released on 1995 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Experimental Hematology

Download or read book Experimental Hematology written by and published by . This book was released on 1977 with total page 1506 pages. Available in PDF, EPUB and Kindle. Book excerpt: