Download or read book Inventing Reactions written by Lukas J. Gooßen and published by Springer. This book was released on 2012-10-30 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Barry Trost: Transition metal catalyzed allylic alkylation.- Jeffrey W. Bode: Reinventing Amide Bond Formation.- Naoto Chatani and Mamoru Tobisu: Catalytic Transformations Involving the Cleavage of C-OMe Bonds.- Gregory L. Beutner and Scott E. Denmark: The Interplay of Invention, Observation and Discovery in the Development of Lewis Base Activation of Lewis Acids for Catalytic Enantioselective Synthesis.- David R. Stuart and Keith Fagnou: The Discovery and Development of a Palladium(II)-Catalyzed Oxidative Cross-Coupling of Two Unactivated Arenes.- Lukas Gooßen and Käthe Gooßen: Decarboxylative Cross-Coupling Reactions.- A. Stephen K. Hashmi: Gold-Catalyzed Organic Reactions.- Ben List: Developing Catalytic Asymmetric Acetalizations.- Steven M. Bischof, Brian G. Hashiguchi, Michael M. Konnick, and Roy A. Periana: The De NovoDesign of CH Bond Hydroxylation Catalysts.- Benoit Cardinal-David, Karl A. Scheidt: Carbene Catalysis: Beyond the Benzoin and Stetter Reactions.- Kenso Soai and Tsuneomi Kawasaki: Asymmetric autocatalysis of pyrimidyl alkanol.- Douglas C. Behenna and Brian M. Stoltz: Natural Products as Inspiration for Reaction Development: Catalytic Enantioselective Decarboxylative Reactions of Prochiral Enolate Equivalents. Hisashi Yamamoto: Acid Catalysis in Organic Synthesis.

Download or read book More Dead Ends and Detours written by Miguel A. Sierra and published by Wiley-VCH. This book was released on 2013-07-11 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success comes in many forms and in synthesis it can be a failure that results in their ultimate successful solutions. This long-awaited sequel to "Dead Ends and Detours" retains the proven concept while featuring over 20 new case studies of failed strategies and their (successful) solutions in natural product total synthesis. Additionally, computational models are used to discuss the problem in much more detail and to provide readers with additional information not found in the primary literature. The topics range from classic synthetic reactions (e.g. Diels Alder reaction), metal-mediated coupling reactions, metathesis, and asymmetric catalysis to the importance of protecting and activating groups. This book will benefit not only graduate students in organic chemistry but also advanced researchers as they gain knowledge derived from the step-by-step analysis of mistakes made in the past and, thus be able to improve their own chemical reaction planning. With its coverage of the most commonly applied reaction types, the book perfectly complements its predecessor, which focuses on general aspects, such as reactivity and selectivity.

Download or read book Sulfur Ylides Emerging Synthetic Intermediates written by Barry M. Trost and published by . This book was released on 1975 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book More Dead Ends and Detours written by Miguel A. Sierra and published by John Wiley & Sons. This book was released on 2013-07-11 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Success comes in many forms and in synthesis it can be a failure that results in their ultimate successful solutions. This long-awaited sequel to "Dead Ends and Detours" retains the proven concept while featuring over 20 new case studies of failed strategies and their (successful) solutions in natural product total synthesis. Additionally, computational models are used to discuss the problem in much more detail and to provide readers with additional information not found in the primary literature. The topics range from classic synthetic reactions (e.g. Diels Alder reaction), metal-mediated coupling reactions, metathesis, and asymmetric catalysis to the importance of protecting and activating groups. This book will benefit not only graduate students in organic chemistry but also advanced researchers as they gain knowledge derived from the step-by-step analysis of mistakes made in the past and, thus be able to improve their own chemical reaction planning. With its coverage of the most commonly applied reaction types, the book perfectly complements its predecessor, which focuses on general aspects, such as reactivity and selectivity.

Download or read book Studies Toward a Total Synthesis of Callipeltoside A written by Hongyu Zhao and published by . This book was released on 2000 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies Directed Towards the Total Synthesis of the Natural Products Avarol and Capentin written by Thomas Elliott Jacks and published by . This book was released on 1993 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies Toward the Total Synthesis of the Venturicidin Aglycone written by Sei-Chang Ahn and published by . This book was released on 1991 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Total Synthesis of Variecolortides A C written by Christian Andreas Kuttruff and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Part 1 Efforts Towards the Total Synthesis of Scyphostatin Part II Synthetic Studies Towards Peloruside A written by Manomi A. Tennakoon and published by . This book was released on 2001 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies Toward the Total Synthesis of Aplysistatin and the Total Synthesis of Ancistrofuran written by Andrew James Caruso and published by . This book was released on 1980 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies Directed Toward the Total Synthesis of jatrophone written by Gary J. Drtina and published by . This book was released on 1983 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthetic Studies Toward the Total Synthesis of Fostriecin and Some Analogs written by Glenn Walton Phillips and published by . This book was released on 2006 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies Toward the Total Synthesis of Camptothecin written by Douglas Arthur Peterson and published by . This book was released on 1971 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies Towards the Total Synthesis of Harringtonolide written by Daniel Harry Rogers and published by . This book was released on 1990 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Total Synthesis of Natural Products the Chiron Approach written by Stephen Hanessian and published by Pergamon. This book was released on 1983 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Total Synthesis of N benzoylated Actinobolin Amine written by Rita Szczepanski King Majerle and published by . This book was released on 1989 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Studies Toward the Mechanism of Bleomycin written by Corin Deann Slown and published by ProQuest. This book was released on 2008 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bleomycins are a class of glycopeptide antitumor antibiotics isolated by Umezawa and coworkers in 1966. Bleomycin A2 is the major component (70%) of the clinical anticancer drug Blenoxane, employed in the treatment of several forms of cancer. Through DNA binding and degradation, a process that is both metal ion and oxygen dependent, bleomycin A2 cleaves double stranded DNA selectively at 5'-GC or 5'-GT sites by minor groove C4'-H atom abstraction and subsequent fragmentation of the deoxyribose backbone. Many key questions concerning the mechanism and functional roles of the structural units still remain unanswered, including the nature of the metal-binding ligands and their arrangement in the metal complexes. Efforts to address these questions include the synthesis of 15N-labeled analogues of the pyrimidoblamic acid as well as the carbamoyl portion of the disaccharide, their incorporation into bleomycin A2 and subsequent Electron Nuclear Double Resonance (ENDOR) spectroscopy studies.