Download or read book Studies on the Relationship Between Chromosome Replication and Cell Division in Escherichia Coli written by Peter A. Meacock and published by . This book was released on 1975 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Bacterial Cell Coupling between Growth Nucleoid Replication Cell Division and Shape Volume 2 written by Ariel Amir and published by Frontiers Media SA. This book was released on 2019-11-14 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 1st volume of our Research Topic "The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division and Shape” was published as an eBook in May 2016 (see: http://journal.frontiersin.org/researchtopic/2905/the-bacterial-cell-coupling-between-growth-nucleoid-replication-cell-division-and-shape). As a sign of growing interest to the topic, two workshops followed the same year: "Stochasticity in the Cell Cycle" in Jerusalem (Israel) by the Hebrew University’s Institute of Advanced Studies and EMBO's "Cell Size Regulation" in Joachimsthal (Germany). From the time of launching the first edition, several new groups have entered the field, and many established groups have made significant advances using state-of-the-art microscopy and microfluidics. Combining these approaches with the techniques pioneered by quantitative microbiologists decades ago, these approaches have provided remarkable amounts of numerical data. Most of these data needed yet to be put into a broader theoretical perspective. Moreover, the molecular mechanisms governing coordination and progression of the main bacterial cell cycle processes have remained largely unknown. These outstanding fundamental questions and the growing interest to the field motivated us to launch the next volume titled “The Bacterial Cell: Coupling between Growth, Nucleoid Replication, Cell Division, and Shape, Volume 2” shortly after completion of the first edition in October 2016. The issue contains 17 contributions from a diverse array of scientists whose field of study spans microbiology, biochemistry, genetics, experimental and theoretical biophysics. The specific questions addressed in the issue include: What triggers initiation of chromosome replication? How is cell division coordinated with replication both spatially and temporally? How is cell size controlled and linked to the rate of mass growth? What role plays physical organization of the chromosomes in their segregation and in regulation of cell division? The publications covering these questions are divided into three topical areas: 1) Cell Cycle Regulation, 2) Growth and Division, and 3) Nucleoid Structure and Replication. New ideas and techniques put forward in these articles bring us closer to understand these fundamental cellular processes, but the quest to resolve them is far from being complete. Plans for the next edition are under way along with further meetings and workshops, e.g., an EMBO Workshop on Bacterial cell biophysics: DNA replication, growth, division, size and shape in Ein Gedi (Israel), May 2020. We hope that via such interdisciplinary exchange of ideas we will come closer to answering the above-mentioned complex and multifaceted questions.
Download or read book DNA Replication Control in Microbial Cell Factories written by Monika Glinkowska and published by Springer. This book was released on 2014-09-23 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested. Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replication initiation may differ depending on growth conditions. Therefore, understanding the regulation of DNA duplication requires placing this process in the context of the current knowledge on bacterial metabolism, as well as cellular and chromosomal structure. Moreover, in both Escherichia coli and eukaryotic cells, replication initiator proteins were shown to play other roles in addition to driving the assembly of replication complexes, which constitutes another, yet not sufficiently understood, layer of coordinating DNA replication with the cell cycle.
Download or read book The Relationship Between DNA Synthesis and Chromosome Transfer in Escherichia Coli written by Noel Patrick Bouck and published by . This book was released on 1969 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Bacterial Cell Coupling between Growth Nucleoid Replication Cell Division and Shape written by Arieh Zaritsky and published by Frontiers Media SA. This book was released on 2016-05-02 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Physiology was inaugurated as a discipline by the seminal research of Maaløe, Schaechter and Kjeldgaard published in 1958. Their work clarified the relationship between cell composition and growth rate and led to unravel the temporal coupling between chromosome replication and the subsequent cell division by Helmstetter et al. a decade later. Now, after half a century this field has become a major research direction that attracts interest of many scientists from different disciplines. The outstanding question how the most basic cellular processes - mass growth, chromosome replication and cell division - are inter-coordinated in both space and time is still unresolved at the molecular level. Several particularly pertinent questions that are intensively studied follow: (a) what is the primary signal to place the Z-ring precisely between the two replicating and segregating nucleoids? (b) Is this coupling related to the structure and position of the nucleoid itself? (c) How does a bacterium determine and maintain its shape and dimensions? Possible answers include gene expression-based mechanisms, self-organization of protein assemblies and physical principles such as micro-phase separations by excluded volume interactions, diffusion ratchets and membrane stress or curvature. The relationships between biochemical reactions and physical forces are yet to be conceived and discovered. This e-book discusses the above mentioned and related questions. The book also serves as an important depository for state-of-the-art technologies, methods, theoretical simulations and innovative ideas and hypotheses for future testing. Integrating the information gained from various angles will likely help decipher how a relatively simple cell such as a bacterium incorporates its multitude of pathways and processes into a highly efficient self-organized system. The knowledge may be helpful in the ambition to artificially reconstruct a simple living system and to develop new antibacterial drugs.
Download or read book Control of Macromolecular Synthesis written by Ole Maaløe and published by . This book was released on 1966 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Initiation of DNA Replication in Escherichia Coli written by Michael Dalbey and published by . This book was released on 1975 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The E Coli Membrane written by Lorraine J. Gudas and published by . This book was released on 1975 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell Synchrony written by Ivan L. Cameron and published by Academic Press. This book was released on 2013-10-02 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell Synchrony: Studies in Biosynthetic Regulation focuses on the processes, principles, applications, methodologies, and approaches involved in biosynthetic regulation, including chromosome replication, cellular biosynthesis, and enzyme synthesis. The selection first takes a look at the theory of synchronous cultures, synchronous replication of the chromosome in Bacillus subtilis, and chromosome replication in Escherichia coli. Discussions focus on attempts to characterize the physical state of replicating DNA, cell division and the regulation of chromosome replication, regulation of sequential chromosome synthesis, synchrony of chromosome replication, and determination of the cell doubling-time distribution function from the decay of synchronization. The text then examines nuclear events in synchronously dividing yeast cultures, periodic enzyme synthesis in synchronous cultures of yeast, and light-induced synchronous sporulation of a myxomycete. Topics include periodicity of enzyme synthesis, use of synchronous cultures for studying cellular biosynthesis, and cytological observations on synchronously dividing cultures. The book explores the effects of temperature on the mitotic cycle of normal and synchronized mammalian cells; behavior of sulfhydryl groups in synchronous division; and morphogenetic and macromolecular aspects of synchronized Tetrahymena. The selection is highly recommended for researchers interested in biosynthetic regulation.
Download or read book Coordination of DNA Replication and Cell Division in Escherichia Coli written by Bela Sharma and published by . This book was released on 1995 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book DNA Replication and Cell Size Control in Escherichia Coli written by Dongyang Li and published by . This book was released on 2018 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: The defining feature of living organisms is their capacity to reproduce and pass on the genetic information so that their progeny can flourish. For bacteria, reproduction is a feat by itself--Escherichia coli cells cultured in optimal conditions grow rapidly and divide about every 20 minutes. In other words, the cell has to replicate all cellular contents, and be ready to divide evenly into two daughter cells within this 20 minutes. Biosynthesis of new cellular materials, e.g. proteins, nucleic acis, lipids and other metabolites accumulate and roughly doubles after every generation. Notably, the deoxyribonucleic acid (DNA) encodes genetic informationand needs to be duplicated in order to faithfully pass on this information to the progeny. This process of DNA replication in the cell needs to dynamically adapt to fluctuation in growth condition and cellular physiology. Such coordination is controlled at the first step of replcation--the initiation of replication. In this thesis, I presented the development of methods for measuring DNA replication duration (replication period), the quantitative relationship between DNA replication and cell size as well as the mechanism of replication initiation. DNA replication measurement laid the foundation of studying the quantitative relationship between cell size and DNA replication. A general growth law was proposed to describe cell size regulation in light of three physiological variables including biosynthesis rate, cell cycle progression and replicaiton initiation. Of the three variables, the mass when cell initiates replication (initiation mass) remains invariant despite a wide spectrum of antibiotics or growth limitation challenge. This invariant initiation mass called into question about the mechanism of initiation to achieve such constancy. We proposed a simple threshold model to explain how cells can maintain a invariant initiation mass by regulating the expression of initiation regulators (initiators). The initiation mass is inversely proportional to the initiator levels, which is held constant. Experimental evidence was provided to test our model prediction.
Download or read book The Cell Cycle written by P. C. L. John and published by Cambridge University Press. This book was released on 1981-12-31 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Duplication of Escherichia Coli written by Ludovicus Johannes Hubertus Koppes and published by . This book was released on 1980 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies on the Continuity of DNA Synthesis in Escherichia Coli written by Patricia Fay Pachler and published by . This book was released on 1964 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cell Division in Cis platinum II diamminodichloride induced Filaments of Escherichia Coli written by Bruce Edward Markham and published by . This book was released on 1980 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Coordination of DNA Replication and Cell Division in Escherichia Coli written by Andrea Cendrowski and published by . This book was released on 2014 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
