Download or read book Studies on Chebulinic Acid Extraction from Terminalia Chebula Species written by Surya Prakash and published by . This book was released on 2013-09 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master's Thesis from the year 2012 in the subject Engineering - Chemical Engineering, grade: -, Andhra University (Andhra University College of Engineering (A)), course: M.Tech Bio Technology, language: English, abstract: Herbal drug product has a special place in the world of pharmaceuticals. Terminalia chebula is a deciduous tree, used in traditional medicines. It is reported to contain various bio chemical compounds such as tannins, chebulinic acid, ellagic acid, gallic acid, punicalagin, flavonoids etc. It has been reported as antioxidant, antidiabetic, antibacterial, antiviral, antifungal, anticancerous, antiulcer, antimutagenic, wound healing activities etc. The optimization of physico-chemical parameters like effects of different solvents, soaking time, extraction time with hexane, particle size, different solvent percentages, different volumes of hexane with ethanol and methanol as solvents and pH for the extraction of Total Phenolic Content, Chebulinic acid and Quercetin were studied. The extraction was carried out by employing various organic solvents using Soxhlet extractor method. Ethanol was found to be the best solvent for the extraction of Chebulinic acid from Terminalia chebula species. Soxhlet extractor was carried out using ethanol at different extraction times to verify the mathematical model proposed in this work. The optimization of physico-chemical parameters required for obtaining the highest production of Chebulinic acid using Baker's yeast (Saccharomyces cerevisia.Among the extraction process (Batch, Soxhlet& Fermentation process) the highest Chebulinic acid production was obtained from fermentation process. The partition coefficient for fermentation, soxhlet & batch extraction were found to be 3.83, 2.0 & 0.64. The extraction of Chebulinic acid from Terminalia chebula by Soxhlet extraction and purify the Chebulinic acid by using Column chromatography. Chebulinic acid showed many bioactivities including inhibition of cancer cell growth,

Download or read book The Extraction and Fermentation Process of Gallic Acid from Composition of Terminalia Species Leaves written by Surya Prakash and published by GRIN Verlag. This book was released on 2018-04-09 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Paper (postgraduate) from the year 2018 in the subject Biology - Botany, grade: A, , course: Biotechnology, language: English, abstract: Gallic acid is showed best results from fermentation process than extraction process due to biotransformation. In this research, the highest concentration of gallic acid was observed to be 8.7 to 9.0 microgram/ml from the soxhlet extraction and column chromatography process, and the concentration was increased to 9.7 microgram/ml from the fermentation process by Bacillus cereus species. The fermented extracts are showed with the maximum specific growth rate and the maximum yield factor (Yx/s) of Bacillus cereus are 0.3541 hr-1 and 0.234 microgram/ml. The non fermented extracts are showed the modelling equation for the quercetin yield extract was Es = 0.0721(1 - e-0.2867t). The model allowed good accordance with the experimental data by producing average absolute relative deviation from about 9.78 percent. Keywords: Terminalia species, Gallic acid, Fermentation, Extraction, Bacillus cereus

Download or read book Studies on Chebulinic Acid Extraction from Terminalia chebula species written by Surya Prakash and published by GRIN Verlag. This book was released on 2013-09-10 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master's Thesis from the year 2012 in the subject Engineering - Chemical Engineering, Andhra University (Andhra University College of Engineering (A)), course: M.Tech Bio Technology, language: English, abstract: Herbal drug product has a special place in the world of pharmaceuticals. Terminalia chebula is a deciduous tree, used in traditional medicines. It is reported to contain various bio chemical compounds such as tannins, chebulinic acid, ellagic acid, gallic acid, punicalagin, flavonoids etc. It has been reported as antioxidant, antidiabetic, antibacterial, antiviral, antifungal, anticancerous, antiulcer, antimutagenic, wound healing activities etc. The optimization of physico-chemical parameters like effects of different solvents, soaking time, extraction time with hexane, particle size, different solvent percentages, different volumes of hexane with ethanol and methanol as solvents and pH for the extraction of Total Phenolic Content, Chebulinic acid and Quercetin were studied. The extraction was carried out by employing various organic solvents using Soxhlet extractor method. Ethanol was found to be the best solvent for the extraction of Chebulinic acid from Terminalia chebula species. Soxhlet extractor was carried out using ethanol at different extraction times to verify the mathematical model proposed in this work. The optimization of physico-chemical parameters required for obtaining the highest production of Chebulinic acid using Baker’s yeast (Saccharomyces cerevisia.Among the extraction process (Batch, Soxhlet& Fermentation process) the highest Chebulinic acid production was obtained from fermentation process. The partition coefficient for fermentation, soxhlet & batch extraction were found to be 3.83, 2.0 & 0.64. The extraction of Chebulinic acid from Terminalia chebula by Soxhlet extraction and purify the Chebulinic acid by using Column chromatography. Chebulinic acid showed many bioactivities including inhibition of cancer cell growth, inhibiting the contractile responses of cardiovascular muscles, anti-fungal, anti-bacterial activities etc. Finally the Chebulinic acid extraction from Terminalia chebula plays a vital role in medicine, biotechnology and various pharmacological activities.

Download or read book Handbook of 200 Medicinal Plants written by Shahid Akbar and published by Springer Nature. This book was released on 2020-04-21 with total page 2076 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.

Download or read book Indian Herbal Remedies written by C.P. Khare and published by Springer Science & Business Media. This book was released on 2011-06-27 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: This superbly illustrated A-Z guide to modern and traditional Indian herbal remedies brings together information from numerous authoritative sources in the form of a highly structured and well-written reference work. Entries for each medicinal plant describe classical Ayurvedic and Unani uses, compare modern findings and applications, together with their pharmacology and therapeutic principles in an evidence-based approach. Information sources include: German Commission E, US Pharmacopoeia/National Formulary, and the WHO. The resulting work highlights the potential of Indian herbs for Western medicine by placing findings on a scientific platform. Over 200 full-colour photographs and 50 drawings illustrate the plants. Includes ayurvedic herbal drugs More than 150 general and more than 500 plant species are covered Easy-to-use and highly structured entries Detailed information on traditional use and modern evidence-based medical application

Download or read book Nanostructures for Oral Medicine written by Ecaterina Andronescu and published by Elsevier. This book was released on 2017-04-11 with total page 1036 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Oral Medicine presents an up-to-date examination of the applications and effects of nanostructured materials in oral medicine, with each chapter addressing recent developments, specific applications, and uses of nanostructures in the oral administration of therapeutic agents in dentistry. The book also includes coverage of the biocompatibility of nanobiomaterials and their remarkable potential in improving human health and in reducing environmental pollution. Emerging advances, such as Dr. Franklin Tay's concept of a new nanotechnology process of growing extremely small, mineral-rich crystals and guiding them into the demineralized gaps between collagen fibers to prevent the aging and degradation of resin-dentin bonding is also discussed. This work will be of great value to those who work in oral medicine, providing them with a resource to gain a greater understanding of how nanotechnology can help them create more efficient, cost-effective products. In addition, it will be of great interest to those who work in materials science who wish to gain a greater appreciation of how nanostructured materials are applied in this field. Outlines the major uses of nanostructured materials for oral medicine, including the properties of each material discussed and how it should best be applied Explores how nanostructured materials enable the creation of more effective drug delivery systems in oral medicine Discusses how novel uses of nanostructured materials may be applied in oral medicine to create more effective devices

Download or read book Bioactive Compounds from Multifarious Natural Foods for Human Health written by Hafiz Ansar Rasul Suleria and published by CRC Press. This book was released on 2022-08-01 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Divided into two sections, the volume first examines health claims of food-based bioactive compounds, which are extra-nutritional constituents that typically occur in small quantities in foods. This section lays out the concepts of extraction of food-based bioactive molecules, along with both conventional and modernized extraction techniques. The book goes to present new research on health claims of bioactive compounds from medicinal plants, their importance, and health perspectives. Both sections cover the various pharmacological and therapeutic aspects of bioactive compounds, along with their methods of extraction, their phytochemistry, their pharmacological and biological activities, their medicinal properties, and their applications for disease management and prevention. This volume sheds new light on the potential of natural and plant-based foods for human health from different technological aspects, contributing to the ocean of knowledge on food science and technology.

Download or read book Dietary Chinese Herbs written by Yanze Liu and published by Springer Science & Business Media. This book was released on 2015-05-18 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents up-to-date information on chemical, pharmacological, clinical studies and historical uses of common dietary Chinese herbs. Authored by native experts in the field, the reader is introduced to each herb with a brief chronological review of Chinese literature on dietary herb uses, with chapters dedicated to each selected herb including color photos for each herb. In addition, Chinese characters as well as the Latin botanical name indices, and chemical structures for the known active compounds are also provided. The clear layout examines the health benefits that have been studied for centuries, including current clinical and toxicological data. A wide range of Traditional Chinese Medicine (TCM) herbs are investigated for their suitability into daily diets for maintaining general wellness or disease prevention. In the past decades, natural health products, dietary supplements, functional foods, or nutraceuticals have emerged in the West due to the increasing demand for non-pharmaceutical healthcare products. Traditional Chinese Medicine disease prevention and treatment incorporates the use of foods, and herbal medicine in an integrated manner, and thus the dietary Chinese herbs in used in TCM for thousands of years could be sources for developing new, effective, and safe ingredients to capture the rapidly expanding opportunity in the global market place.

Download or read book Bioprospecting of Plant Biodiversity for Industrial Molecules written by Santosh Kumar Upadhyay and published by John Wiley & Sons. This book was released on 2021-06-22 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: BIOPROSPECTING OF PLANT BIODIVERSITY FOR INDUSTRIAL MOLECULES A comprehensive collection of recent translational research on bioresource utilization and ecological sustainability Bioprospecting of Plant Biodiversity for Industrial Molecules provides an up-to-date overview of the ongoing search for biodiverse organic compounds for use in pharmaceuticals, bioceuticals, agriculture, and other commercial applications. Bringing together work from a panel of international contributors, this comprehensive monograph covers natural compounds of plants, endophyte enzymes and their applications in industry, plant bioprospecting in cosmetics, marine bioprospecting of seaweeds, and more. Providing global perspectives on bioprospecting of plant biodiversity, the authors present research on enzymes, mineral micro-nutrients, biopesticides, algal biomass, and other bioactive molecules. In-depth chapters assess the health impacts and ecological sustainability of the various biomolecules and identify existing and possible applications ranging from ecological restoration to production of essential oils and cosmetics. Other topics include, bio-energy crops as alternative fuel resources, the role of plants in phytoremediation of industrial waste, and the industrial applications of endophyte enzymes. This comprehensive resource: Includes a through introduction to plant biodiversity and bioprospecting Will further the knowledge of application of different plants and improve research investigation techniques. Summarizes novel approaches for researchers in food science, microbiology, biochemistry, and biotechnology Bioprospecting of Plant Biodiversity for Industrial Molecules is an indispensable compendium of biological research for scientists, researchers, graduate and postgraduate students, and academics in the areas of microbiology, food biotechnology, industrial microbiology, plant biotechnology, and microbial biotechnology.

Download or read book Drug Discovery and Development written by Ramarao Poduri and published by Springer Nature. This book was released on 2021-02-15 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the processes that are involved in the development of new drugs. The authors discuss the history, role of natural products and concept of receptor interactions with regard to the initial stages of drug discovery. In a single, highly readable volume, it outlines the basics of pharmacological screening, drug target identification, and genetics involved in early drug discovery. The final chapters introduce readers to stem therapeutics, pharmacokinetics, pharmacovigilance, and toxicological testing. Given its scope, the book will enable research scholars, professionals and young scientists to understand the key fundamentals of drug discovery, including stereochemistry, pharmacokinetics, clinical trials, statistics and toxicology.

Download or read book New Look to Phytomedicine written by Mohd Sajjad Ahmad Khan and published by Academic Press. This book was released on 2018-10-23 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Look to Phytomedicine: Advancements in Herbal Products as Novel Drug Leads is a compilation of in-depth information on the phytopharmaceuticals used in modern medicine for the cure and management of difficult-to-treat and challenging diseases. Readers will find cutting-edge knowledge on the use of plant products with scientific validation, along with updates on advanced herbal medicine in pharmacokinetics and drug delivery. This authoritative book is a comprehensive collection of research based, scientific validations of bioactivities of plant products, such as anti-infective, anti-diabetic, anti-cancer, immune-modulatory and metabolic disorders presented by experts from across the globe. Step-by-step information is presented on chemistry, bioactivity and the functional aspects of biologically active compounds. In addition, the pharmacognosy of plant products with mechanistic descriptions of their actions, including pathogenicity is updated with information on the use of nanotechnology and molecular tools in relation to herbal drug research. Compiles up-to-date information on the chemotherapeutics used in the treatment of infective and metabolic disorders Presents advancements in the discovery of new drugs from plants using molecular and nanotechnology tools Examines detailed information on the use of herbals agents in cancer, HIV and other ailments, including diabetes, malaria and neurological disorders

Download or read book Medicinal Plants of India Vol 1 written by D. Jadhav and published by Scientific Publishers. This book was released on 2008-07-01 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book deals with 200 plants species of Angiosperms. For the first time here is a detailed explaination of 200 herbs in complete Ayurvedic perspective, aided with their botanical description, chemical constituents, Ayurvedic medicinal properties, clinical usage and also ethno-medicinal usage. The plants selected in the present book are fairly widely used in India for millennia. This book well help in generating a global interest in Ayurveda and medicinal plants in India. The author has done a commendable job to compile the useful information of plants, in addition with excellent coloured photograph, which facilitates its identification. Salient features of this Book are: (1) Species of plants are presented in Alphabetical order of their Botanical names. (2) In dealing with each species, after its Botanical name, all available Synonyms are mentioned. (3) This is followed by names popularly used in English and in other Indian languages with its distribution. (4) To help to identify the plant species, the taxonomic description is given. (5) Available information about the chemical constituents of each species is given. (6) Sanskrit Shlokas from relevent Nighantus describing the Ayurvedic Medicinal properties are first given in Devanagary Script followed by its rendering in Roman Script using Internationally recognized transliteration markings. (7) This is followed by giving its action and uses according to Ayurvedic therapeutics. (8) Information about its use in Ethnomedicinal practice is given, then. This book is helpful for Ethnobotanists, Ayurvedic medical practitioner, students and researchers as well as other reader's interested in the field of Ethno-medicine.

Download or read book WHO Monographs on Selected Medicinal Plants written by World Health Organization and published by World Health Organization. This book was released on 1999 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second volume in a series of monographs which are intended to promote information exchange and international harmonised standards for the quality control and use of herbal medicines. It contains scientific information on 30 selected plants, and each entry includes a pharmacopoeial summary for quality assurance purposes, information on its clinical application and sections on contraindications, pharmacology, safety issues, and dosage forms. It provides two cumulative indexes with entries in alphabetical order by plant name and according to the plant material of interest.

Download or read book Phytochemical Investigations of Genus Terminalia written by Brijesh Kumar and published by CRC Press. This book was released on 2021-07-27 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genus Terminalia is known to be a rich source of secondary metabolites, mainly polypohenols and triterpenoids. About 39 species have been phytochemically studied leading to the identification of 368 compounds. This work involves the use of hyphenated mass spectrometric methods such as HPLC-ESI-QTOF-MS/MS and UPLC-ESI-QqQLIT-MS/MS for qualitative and quantitative analysis of major bioactive constituents in selected medicinal plants without isolation. It also describes the methods of mass fingerprinting and their use to investigate the plant species variations with the help of statistical software’s (PCA). Markers were identified for quality control and authentications.

Download or read book Phytotherapy written by Francesco Capasso and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated reference guide treats the subject of herbal medicines in an integrated fashion with reference to pharmacognosy, pharmacology and toxicology. It will help to enable internists, phytotherapists, physicians, healthcare practitioners as well as students to understand why, when and how herbal medicines can be used in the treatment of diseases. A great deal of pathology and therapeutic information is also included. Numerous tables as well as figures clarify complex mechanisms and other information. The most important medicinal plants and drugs are illustrated with exceptional color plates.

Download or read book Biological Oxidants and Antioxidants written by Lester Packer and published by Aocs Publishing. This book was released on 1998 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the proceedings of the SFRR-Asia/COSTAM/UNESCO-MCBN Workshop on Biological Oxidants and Antioxidants: Molecular Mechanisms and Health Effects. This workshop covered topics of fundamental importance in basic biological research and in the biomedical sciences.

Download or read book Dravyagu a Vij na A J written by Dr. Gyanendra Pandey and published by . This book was released on 1998 with total page 968 pages. Available in PDF, EPUB and Kindle. Book excerpt: On Ayurvedic system in Indic medicine.