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Book Studies on Cell mediated Immunity to Listeria Monocytogenes in Guinea Pigs and Modulation of Tumor Growth with Listeria

Download or read book Studies on Cell mediated Immunity to Listeria Monocytogenes in Guinea Pigs and Modulation of Tumor Growth with Listeria written by Meher Manek Dustoor and published by . This book was released on 1976 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Acquired Cellular Resistance and Delayed Hypersensitivity in Guinea Pigs Infected with Listeria Monocytogenes

Download or read book Acquired Cellular Resistance and Delayed Hypersensitivity in Guinea Pigs Infected with Listeria Monocytogenes written by Barbara Lee Halliburton and published by . This book was released on 1973 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Influence of Environmental Factors and the Host s Susceptibility on the Development of Listeria Monocytogenes Infection in the Guinea Pig Model

Download or read book Influence of Environmental Factors and the Host s Susceptibility on the Development of Listeria Monocytogenes Infection in the Guinea Pig Model written by Hoan-Jen Eunice Pang and published by . This book was released on 2007 with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: Listeria monocytogenes is an intracellular pathogen commonly associated with ready-to-eat foods. Using the guinea pig model, the impact of environmental factors on the infectivity of L. monocytogenes, as well as the impact of a host's immunity, on the development of listerial infection was investigated. Experiments were conducted to determine whether exposure to food environment and improper handling conditions impact the infectivity of L. monocytogenes. Results indicated that the virulence of L. monocytogenes was not influenced by exposure of the pathogen to food or improper handling conditions. In young adult guinea pigs orally challenged with 102 L. monocytogenes, a 27% infection rate occurred. Further studies were conducted to determine the impact of immunomodulation of a host's immunity on the development of listerial infection using aged guinea pigs. Flow cytometry analysis showed that daily supplementation with vitamin E significantly increased the level of CD8+ T cells, while cyclosporine A (CsA) treatment resulted in a 25% decrease of CD8+ T cells. HPLC analysis showed that short-term supplementation with vitamin E resulted in an overall 1-fold increase in the plasma alpha-tocopherol concentration. In low-dose (102 CFU) challenged animals, 50% of the control-group animals became infected. Only 22% of animals receiving the orthomolecular dose of vitamin E became infected, whereas animals that were immunosuppressed had an infection rate of 89%. In the immunosuppressed group three animals (16%) developed listerial infection with a quantifiable bacterial level of 0.3-3 log CFU g( -1) of organ in the spleen and liver. In the high-dose study, the population of L. monocytogenes was consistently 1 log CFU lower in the spleen and liver of animals in the vitamin E group as compared to the control and CsA-treated groups. The level of L. monocytogenes was not significantly different between the control and CsA-treated groups. The results suggest that immunomodulation of the host can influence listerial infection within an aged population of guinea pigs. From a public health perspective, the research indicates that a low oral dose of L. monocytogenes may pose a human health risk.

Book Inflammasome Activation Impairs Cell mediated Immunity to Listeria Monocytogenes

Download or read book Inflammasome Activation Impairs Cell mediated Immunity to Listeria Monocytogenes written by Erin M. Theisen and published by . This book was released on 2017 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Dissertation Abstracts International

Download or read book Dissertation Abstracts International written by and published by . This book was released on 1986 with total page 758 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book American Doctoral Dissertations

Download or read book American Doctoral Dissertations written by and published by . This book was released on 1977 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Research Awards Index

Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Current Research on Pre clinical Aspects of Cancer Therapy

Download or read book Current Research on Pre clinical Aspects of Cancer Therapy written by Current Cancer Research Project Analysis Center (U.S.) and published by . This book was released on 1975 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1038 references to research projects being conducted in the United States and elsewhere. Entries arranged under 5 topics, e.g., Preclinical studies of anticancer drugs, Preclinical radiation therapy, and Preclinical immunotherapy. Entriesinclude title, researcher, address, contract number, summary, and supporting agency. Indexes by subjects, investigators, contractors, supporting agencies, and contractor numbers.

Book Comprehensive Dissertation Index

Download or read book Comprehensive Dissertation Index written by and published by . This book was released on 1984 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Cumulated Index Medicus

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1993 with total page 1488 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Biomedical Index to PHS supported Research

Download or read book Biomedical Index to PHS supported Research written by and published by . This book was released on 1990 with total page 866 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Current Bibliography of Epidemiology

Download or read book Current Bibliography of Epidemiology written by and published by . This book was released on 1977 with total page 1076 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monthly, with annual cumulations. Comprehensive, current index to periodical medical literature intended for use of practitioners, investigators, and other workers in community medicine who are concerned with the etiology, prevention, and control of disease. Citations are derived from MEDLARS tapes for Index medicus of corresponding date. Arrangement by 2 sections, i.e., Selected subject headings, and Diseases, organisms, vaccines. No author index.

Book Subject Index of Current Extramural Research Administered by the National Cancer Institute

Download or read book Subject Index of Current Extramural Research Administered by the National Cancer Institute written by National Cancer Institute (U.S.) and published by . This book was released on 1976 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides information concerning research grants and contracts supported by the National Cancer Institute.