Download or read book Studies on Amino Acid Activation and Protein Synthesis written by John Magruder Clark and published by . This book was released on 1958 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book PET Studies on Amino Acid Metabolism and Protein Synthesis written by B.M. Mazoyer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parameters such as membrane transport, metabolism and protein incorporation govern the fate of amino acids in living tissue. Is it possible to use positron tomography to measure some of them, and what is their meaning in normal and pathological situations? These questions have been addressed for a long time and no satisfactory answer has yet been given. This book, which derives from an EEC workshop organized in the frame of the Concerted Action on `PET Investigation of Cellular Regeneration and Degeneration', held in Lyon in February 1992, gives the present state of knowledge in this field based on the most recent studies. Contributions from 24 leading European and American scientists are presented and discussed in the following four parts: biochemistry and animal studies; amino acids labelling with positron emittors, quality control and metabolites measurement; kinetic modelling of amino acids transport, metabolism, and protein incorporation; clinical use of amino acids. This book will aid and interest biochemists, radiochemists, pharmacologists, neurologists, oncologists and medical imaging scientists.
Download or read book Signaling Pathways for Translation written by Robert E. Rhoads and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: The articles in the present volume are by major contributors to our under standing of signaling pathways affecting protein synthesis. They focus pri marily on two extracellular anabolic signals, although others are included as well. Insulin is one of the best-studied extracellular regulators of protein syn thesis. Several of the known pathways for regulation of protein synthesis were elucidated using insulin-dependent systems. Regulation of protein synthesis by amino acids, by contrast, is an emerging field that has recently received a great deal of attention. The dual role of amino acids as substrates for protein syn thesis and regulators of the overall process has only recently been recognized. Since amino acids serve as precursors for proteins, one might expect that with holding an essential amino acid would inhibit the elongation phase. Surpris ingly, research has shown that it is the initiation phase of protein synthesis that is restricted during amino acid starvation. Understanding the mechanisms by which the biosynthesis of proteins is reg ulated is important for several reasons. Protein synthesis consumes a major portion of the cellular ATP that is generated. Therefore, small changes in protein synthesis can have great consequences for cellular energy metabolism. Translation is also a major site for control of gene expression, since messenger RNAs differ widely in translational efficiency, and changes to the protein syn thesis machinery can differentially affect recruitment of individual mRNAs.
Download or read book The Role of Protein and Amino Acids in Sustaining and Enhancing Performance written by Institute of Medicine and published by National Academies Press. This book was released on 1999-09-15 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.
Download or read book The Aminoacyl tRNA Synthetases written by Michael Ibba and published by CRC Press. This book was released on 2005-04-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: By virtue of their role as catalysts of the aminoacylation reaction, the aminoacyl-tRNA synthetases ensure that the first step of translation is performed quickly and accurately. In this volume of 36 separate chapters, the many facets of this ancient and ubiquitous family are reviewed, including their surprising structural diversity, enzymology, tRNA interaction properties, and curious alternative functions. These chapters illustrate the degree to which the aminoacyl-tRNA synthetases employ a variety of mechanisms to carry out both the standard functions related to the synthesis of aminoacylated tRNA for protein synthesis, as well as the surprising functions associated with amino acid biosynthesis, cytokine function, and even the processivity of DNA replication. Other chapters explore the regulation of their synthesis, their role in disease, and their prospects as targets for antibacterial therapeutics. This monograph will be a valuable resource for all scientists interested in the fundamentals of protein synthesis from both a basic research and clinical perspective, as well as the relation of translational components to the evolution of the genetic code.
Download or read book Methods for Investigation of Amino Acid and Protein Metabolism written by Antoine E. El-Khoury and published by Routledge. This book was released on 2017-10-05 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing all the new as well as classical methodologies used in the investigation of amino acid and protein metabolism in human and animal models, this book is needed because of the dramatic increase in research in this field. There is no other book currently on the market that covers these methods of investigation. Methods for Investigation of Amino Acid and Protein Metabolism explores areas such as amino acid transfer across tissue membranes, past and new applications using stable isotopes, protein synthesis in organs and tissues, and more. Because of the importance of research methods in the field of amino acid and protein nutrition and metabolism, this book facilitates the reader's integration of the concepts involved in these investigative research methods and their corollaries. In addition to helping any nutrition investigator design and conduct appropriate research protocols in this area of nutrition, this book assists students who are planning to investigate amino acid and protein metabolism in humans or laboratory animals.
Download or read book The Biosynthesis of Proteins written by H. Chantrenne and published by Pergamon. This book was released on 1961 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Amino Acid Activation written by Adrianus Marinus van de Ven and published by . This book was released on 1957 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies in Protein Synthesis Using Labeled Amino Acids written by Melvin Simpson and published by . This book was released on 1949 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Protein Biosynthesis written by Robert John Cecil Harris and published by . This book was released on 1961 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies on Amino Acid Incorporation in Proteins written by David George Cornwell and published by . This book was released on 1955 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Study of Protein Expression and Enzyme Selectivity Using Unnatural Amino Acids written by Zhongqiang Wang and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: A study of substrate selectivity of aminoacyl-tRNA synthetases, from both bacterial and eukaryotic organisms, using unnatural amino acids is described and discussed in this thesis. The first part of this thesis involved an investigation of the substrate selectivity of bacterial (E. coli) aminoacyl-tRNA synthetases, by protein synthesis using unnatural amino acids via bacterial (E. coli) wild-type machinery. The levels of unnatural amino acid incorporation obtained are discussed in relation to the substrate selectivity of aminoacyl-tRNA synthetases. This work clearly shows that the E. coli TrpRS (Chapter One), the E. coli PheRS (Chapter Two) and the E. coli TyrRS (Chapter Three) display some degree of substrate promiscuity. An HPLC technique has been used to determine the relative rate of unnatural amino acid activation by E. coli TyrRS for a series of meta- and ortho-substituted tyrosines. This work, which is discussed in Chapter Four, shows that the reaction rate of aminoacylation is significantly affected by the substituent on the aromatic ring of tyrosine. The other part involved a study of the substrate selectivity of eukaryotic aminoacyl-tRNA synthetase. Although the original work, which was conducted to investigate the substrate selectivity of eukaryotic PheRS and TyrRS by incorporating the unnatural amino acids into protein with a eukaryotic protein synthesis system and is discussed in Chapter Five, had been unsuccessful, an investigation of the human TyrRS with a series of meta- and ortho-substituted tyrosines using the ITC technique, which is discussed in Chapter Six, shows some degree of substrate promiscuity of human TyrRS. In addition, a selectivity comparison made between the bacterial (E. coli) and the eukaryotic (human) TyrRSs, which is also discussed in Chapter Six, shows that there is difference between these two enzymes regarding substrate selectivity, resulting in the discovery of two organic compounds that could potentially be developed as antimicrobial agents.
Download or read book Amino Acid Biogenesis and Protein Synthesis written by University of California, Los Angeles. Dept. of Chemistry and published by . This book was released on 1955 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Absorption and Utilization of Amino Acids written by Mendel Friedman and published by CRC Press. This book was released on 2019-01-08 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing 45 papers written by outstanding international authors from 14 countries, this three-volume compendium brings together the elements needed to understand the factors which influence the utilization of amino acids. The wide-ranging topics include descriptions of metabolic pathways and mechanisms of the biological utilization of amino acids, as well as factors that influence amino acid bioavailability in enteral and parenteral nutrition. The use of amino acids to improve the quality and safety of the diet is presented. Also discussed are amino acid precursors of biogenic amines and the role of amino acids in atherosclerosis, cancer, and immunity. Scientists from many disciplines will benefit from this broad overview.
Download or read book Absorption and Utilization of Amino Acids written by Mendel Friedman and published by CRC Press. This book was released on 2018-04-19 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing 45 papers written by outstanding international authors from 14 countries, this three-volume compendium brings together the elements needed to understand the factors which influence the utilization of amino acids. The wide-ranging topics include descriptions of metabolic pathways and mechanisms of the biological utilization of amino acids, as well as factors that influence amino acid bioavailability in enteral and parenteral nutrition. The use of amino acids to improve the quality and safety of the diet is presented. Also discussed are amino acid precursors of biogenic amines and the role of amino acids in atherosclerosis, cancer, and immunity. Scientists from many disciplines will benefit from this broad overview.
Download or read book Biology for AP Courses written by Julianne Zedalis and published by . This book was released on 2017-10-16 with total page 1923 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
