Download or read book Studies of Photoreceptor Throughput to Visual Cortex written by Issac Rhim and published by . This book was released on 2021 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The work in this dissertation aims to (1) examine the presence of a functional map in the mouse visual cortex by measuring its variable cone M-opsin and S-opsin inputs, as predicted by the graded dorsoventral cone opsin expression in the retina (Rhim et al., 2017), (2) devise a method for measuring rod saturation and utilize it to characterize differential spatio-temporal tuning between rod-mediated and cone-mediated vision in V1 (Rhim et al., 2021), and (3) study the representation of color and form. We report that the dorsoventral cone opsin expression gradient in the retina is recapitulated in the mouse visual cortex, including primary visual cortex (V1) and higher visual areas (HVAs). This provides a first finding of a functional map in the mouse cortex, next to retinotopy map. Next, we exploit this feature in the mouse cortex to measure variable opsin inputs to the cortex to provide a model to estimate rod saturation. This is a much-needed foundation in mouse vision research, which will help future studies to differentially quantify inputs from the three photoreceptor opsins found in mice: rhodopsin, S-opsin, and M-opsin. We exemplify this by studying the spatio-temporal tuning of rod-mediated vs. cone-mediated vision in V1. Cone-mediated V1 responds to 2.5-fold higher temporal frequencies than rod-mediated V1, highlighting differences in rod vs. cone information throughput. Lastly, we study the mechanisms underlying spatio-chromatic processing in the cortex. We find that V1’s spatial frequency (SF) tuning is more low-pass to color contrast than brightness (i.e., luminance) contrast. Furthermore, our data can be accounted by a random wiring model with rhodopsin and cone S-opsin inputs to single-opponent V1 neurons. While classic models of single-opponency require selective wiring for ON and OFF subfields from each photoreceptor class, we find this to be inconsistent with our data. This provides a new insight to mechanism underlying color vision

Download or read book The Neural Basis of Early Vision written by A. Kaneko and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers in recent decades have elucidated signal transduction in the retina and the function of the visual cortex. The highly flexible nature of neural circuits in the visual cortex especially during the critical period has been an interesting subject for studying neural plasticity and development. Recent advances in the visual neurosciences of the vertebrate retina and the visual cortex were discussed during the 12th Keio International Symposium for Life Science and Medicine, meeting jointly with Vision Forum 2002. Contributions to the symposium collected in this volume reflect the convergence of physiological, cell biological, molecular, mathematical, and clinical approaches. The book covers topics ranging from phototransduction to visual information processing in the primary visual cortex, and includes clinical studies on hereditary night blindness, creating a valuable source of information for researchers and clinicians in the visual neurosciences.

Download or read book Parallel Processing in the Visual System written by Jonathan Stone and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the mid-sixties, John Robson and Christina Enroth-Cugell, without realizing what they were doing, set off a virtual revolution in the study of the visual system. They were trying to apply the methods of linear systems analysis (which were already being used to describe the optics of the eye and the psychophysical performance of the human visual system) to the properties of retinal ganglion cells in the cat. Their idea was to stimulate the retina with patterns of stripes and to look at the way that the signals from the center and the antagonistic surround of the respective field of each ganglion cell (first described by Stephen Kuffier) interact to generate the cell's responses. Many of the ganglion cells behaved themselves very nicely and John and Christina got into the habit (they now say) of calling them I (interesting) cells. However. to their annoyance, the majority of neurons they recorded had nasty, nonlinear properties that couldn't be predicted on the basis of simple summ4tion of light within the center and the surround. These uncoop erative ganglion cells, which Enroth-Cugell and Robson at first called D (dull) cells, produced transient bursts of impulses every time the distribution of light falling on the receptive field was changed, even if the total light flux was unaltered.

Download or read book Webvision written by Helga Kolb and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book High Resolution Imaging in Microscopy and Ophthalmology written by Josef F. Bille and published by Springer. This book was released on 2019-08-13 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book provides a comprehensive overview of the application of the newest laser and microscope/ophthalmoscope technology in the field of high resolution imaging in microscopy and ophthalmology. Starting by describing High-Resolution 3D Light Microscopy with STED and RESOLFT, the book goes on to cover retinal and anterior segment imaging and image-guided treatment and also discusses the development of adaptive optics in vision science and ophthalmology. Using an interdisciplinary approach, the reader will learn about the latest developments and most up to date technology in the field and how these translate to a medical setting. High Resolution Imaging in Microscopy and Ophthalmology – New Frontiers in Biomedical Optics has been written by leading experts in the field and offers insights on engineering, biology, and medicine, thus being a valuable addition for scientists, engineers, and clinicians with technical and medical interest who would like to understand the equipment, the applications and the medical/biological background. Lastly, this book is dedicated to the memory of Dr. Gerhard Zinser, co-founder of Heidelberg Engineering GmbH, a scientist, a husband, a brother, a colleague, and a friend.

Download or read book Advances in Photoreception written by National Research Council and published by National Academies Press. This book was released on 1990-02-01 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of a continuing series on Frontiers of Visual Science, this short volume contains papers presented at a recent symposium. These papers describe techniques for assessing the structure and function of photoreception, both in isolation and in aggregation as the "receptor mosaic" of the retina. Also described are dynamic and spatial sampling properties of photoreceptors, with an emphasis on techniques of measurement and associated models of retinal function. This volume should be of interest to basic vision scientists, clinical ophthalmologists, workers in human factors, and computer scientists curious about the visual apparatus of biological systems.

Download or read book The Roots of Visual Awareness written by C.A. Heywood and published by Elsevier. This book was released on 2003-10-31 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume was assembled in honor of Professor Alan Cowey FRS, and attempts to embrace his wide range of research interests in visual neuroscience. It is divided into four sections. The first contains a group of papers dealing with different fundamental aspects of the visual system, including the control and monitoring of eye movements. The second is concerned with the functional organization of cortical visual areas and their role in visual perception and visually guided action. The third addresses issues concerning color and motion perception, along with broader questions of visual attention; and the effects of selective brain damage on these different aspects of visual experience. The fourth and final section of the volume deals explicitly with questions relating to visual awareness, with particular emphasis on 'blindsight', a topic on which Alan Cowey has worked extensively in recent years, both in humans and in monkeys.

Download or read book The Neural Basis of Early Vision written by A Kaneko and published by . This book was released on 2003-07-02 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers in recent decades have elucidated signal transduction in the retina and the function of the visual cortex. The highly flexible nature of neural circuits in the visual cortex especially during the critical period has been an interesting subject for studying neural plasticity and development. Recent advances in the visual neurosciences of the vertebrate retina and the visual cortex were discussed during the 12th Keio International Symposium for Life Science and Medicine, meeting jointly with Vision Forum 2002. Contributions to the symposium collected in this volume reflect the convergence of physiological, cell biological, molecular, mathematical, and clinical approaches. The book covers topics ranging from phototransduction to visual information processing in the primary visual cortex, and includes clinical studies on hereditary night blindness, creating a valuable source of information for researchers and clinicians in the visual neurosciences.

Download or read book Physiology of Photoreceptor Organs written by Michelangelo G.F. Fuortes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a collection of essays which attempts to summarize the recent progress in the field of photoreceptor and retinal physiology. Reflecting the way in which research is organized, each author reports on the studies performed with the techniques with which he is most familiar: morpholo gical, chemical or physiological. The first chapters describe the structure of visual cells and the histological architecture of the retina. Next comes a summary of the laws governing photochemical reactions and a report on the biochemistry of photopigments. Four articles cover the optical properties of invertebrate eyes and the electrophysiology and the interactions of their photoreceptors. These are followed by a discussion of the properties of vertebrate eyes, including chapters on optics, on the electrical responses of rods and cones and on the functional organization of the retina. The final chapter provides an extensive review of retinal biochemistry and metabolism. Even though the experimental approach differs, all studies are directed toward the solution of two basic problems: transduction in the photoreceptors and orga nization (often called "information processing") in the retina. The central problem of photoreceptor cells is to determine how light produces a response. We know that illumination evokes electrical changes and we have recently learned a great deal about the features of these changes. The evidence indicates however that elaborate processes must be interposed between the ab sorption of photons by the pigment and the production of electric currents through the membrane. These intermediary cvents remain to be unraveled.

Download or read book Vertebrate Photoreceptors written by Takahisa Furukawa and published by Springer Science & Business Media. This book was released on 2014-04-15 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a series of comprehensive views on various important aspects of vertebrate photoreceptors. The vertebrate retina is a tissue that provides unique experimental advantages to neuroscientists. Photoreceptor neurons are abundant in this tissue and they are readily identifiable and easily isolated. These features make them an outstanding model for studying neuronal mechanisms of signal transduction, adaptation, synaptic transmission, development, differentiation, diseases and regeneration. Thanks to recent advances in genetic analysis, it also is possible to link biochemical and physiological investigations to understand the molecular mechanisms of vertebrate photoreceptors within a functioning retina in a living animal. Photoreceptors are the most deeply studied sensory receptor cells, but readers will find that many important questions remain. We still do not know how photoreceptors, visual pigments and their signaling pathways evolved, how they were generated and how they are maintained. This book will make clear what is known and what is not known. The chapters are selected from fields of studies that have contributed to a broad understanding of the birth, development, structure, function and death of photoreceptor neurons. The underlying common word in all of the chapters that is used to describe these mechanisms is “molecule”. Only with this word can we understand how these highly specific neurons function and survive. It is challenging for even the foremost researchers to cover all aspects of the subject. Understanding photoreceptors from several different points of view that share a molecular perspective will provide readers with a useful interdisciplinary perspective.

Download or read book Visual Transduction And Non Visual Light Perception written by Joyce Tombran-Tink and published by Springer Science & Business Media. This book was released on 2008-08-11 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing radiation outside of the visible wavelengths. Comprehensive and penetrating, the book brings together the mechanisms of the visual transduction cascade and is an invaluable text for everyone conducting research in the visual system.

Download or read book The First Steps in Seeing written by Robert W. Rodieck and published by Sinauer Associates Incorporated. This book was released on 1998-01-01 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: The First Steps in Seeing is about the eyes, and how they capture an image and convert it to the neural messages that ultimately result in visual experience. A full appreciation of how the eyes work is rooted in diverse areas of science-optics; biochemistry and photochemistry; molecular biology, cell biology, neurobiology, and evolutionary biology; psychology and psychophysics. The findings related to vision from any one of these fields are not difficult to understand in themselves, but, in order to be clear and precise, each discipline has developed its own set of words and conceptual relations-in effect, its own language-and for those wanting a broad introduction to vision these separate languages can present more of an impediment to understanding than an aid. However, what lies beneath these words usually has a beautiful simplicity, and it is the aim of The First Steps in Seeing to describe how we see in a manner that is understandable to all. In this book, the use of technical terms is restricted, and several hundred full-color illustrations ensure that the terms that are used are associated with a picture, icon, or graph that visually expresses their meaning. Experimental findings have been recast in terms of the natural world whenever possible, and broad themes bring together lines of thought that are often treated separately. Fourteen main chapters form a "thread" that tells the main scientific story and can be read without specialized knowedge or reliance on other sources. This thread is linked to fourteen discussions which explore certain crucial topics in greater depth. Notes link the material presented in the thread and in the special topics discussions to important review articles and seminal research papers. The First Steps in Seeing is an innovative, authoritative work that belongs in the library of anyone with an interest in visual perception.

Download or read book Physiology of Photoreceptor Organs written by Israel Abramov and published by Springer. This book was released on 1972 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Perception of the Visual Environment written by Ronald G. Boothe and published by Springer Science & Business Media. This book was released on 2006-04-12 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at students taking a course on visual perception, this textbook considers what it means for a man, a monkey and a computer to perceive the world. After an introduction and a discussion of methods, the book deals with how the environment produces a physical effect, how the resulting "image" is processed by the brain or by computer algorithms in order to produce a perception of "something out there". It also discusses color, form, motion, distance, and also the sensing of three dimensionality, before dealing with visual perception and its role in awareness and consciousness. The book concludes with discussions of perceptual development, blindness, and visual disorders. Visual perception is by its very nature an interdisciplinary subject that requires a basic understanding of a range of topics from diverse fields, and this is a very readable guide to all students whether they come from a neuroscience, psychology, cognitive science, robotics, or philosophy background.

Download or read book Foundations of Vision written by Brian A. Wandell and published by Sinauer Associates, Incorporated. This book was released on 1995 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for students, scientists and engineers interested in learning about the core ideas of vision science, this volume brings together the broad range of data and theory accumulated in this field.

Download or read book Physiology of Photoreceptor Organs written by Michelangelo G. F. Fuortes and published by . This book was released on 1972-12-11 with total page 820 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Advances in Cognitive Neurodynamics VII written by Alessandra Lintas and published by Springer Nature. This book was released on 2021-09-30 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains original articles submitted to the Seventh International Conference on Cognitive Neurodynamics (ICCN 2019). The brain is an endless case study of a complex system characterized by multiple levels of integration, multiple time scales of activity, and multiple coding and decoding properties. The contribution of several disciplines, mathematics, physics, computer science, neurobiology, pharmacology, physiology, and behavioral and clinical sciences, is necessary in order to cope with such seemingly unattainable complexity that transforms the experimental information into a tricky puzzle which hides the correspondence with model predictions. This conference gathered active participants to discuss ideas and pose new questions from different viewpoints, ranging from single neurons and neural networks to animal/human behavior in theoretical and experimental studies. The conference is organized with plenary lectures, mini-symposia, interdisciplinary round tables, and oral and poster sessions.