Download or read book Structure and Dynamics of Biopolymers written by C. Nicolini and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This NATO-ASI on BIOPOLYMERS STRUCTURE AND DYNAMICS held between 22nd June 4th July 1986 at Erice (Italy) has brought together scientists from a broad variety of biophysical disciplines - polymer physics, biophysics and physical chemistry, structure and dynamics of polynucleotides, proteins, and polysaccharides - to present the current state of knowledge in their fields, both experimental and theoretical. This Advanced Study Institute was indeed a successfull attempt to enhance the possibility of intersection of a number of research lines that currently are progressing well but are still running largely in parallel with one another: protein folding, single-polymer phase transitions, DNA condensation into liquid crystalline-like arrays, packaging in viruses, and polysaccharide gel formation. Although each phenomenon is distinctive, an awareness of similarities may lead to new ic;leas. The program has emphasized "condensed" forms of biopolymers. We are universally confronted in biology by chain polymers folded on themselves or interlinked in gel-like assemblies, whether we look at the native structure of proteins, the role of polysaccharides in connective tissue, or the genetic apparatus. A number of lectures have been devoted to condensed forms of DNA - closed circular supercoils, toruses, chromatin.
Download or read book Structure and Dynamics of Biopolymers written by C Nicolini and published by . This book was released on 1987-06-30 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structure and Dynamics of Confined Polymers written by John J. Kasianowicz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers are essential to biology because they can have enough stable degrees of freedom to store the molecular code of heredity and to express the sequences needed to manufacture new molecules. Through these they perform or control virtually every function in life. Although some biopolymers are created and spend their entire career in the relatively large free space inside cells or organelles, many biopolymers must migrate through a narrow passageway to get to their targeted destination. This suggests the questions: How does confining a polymer affect its behavior and function? What does that tell us about the interactions between the monomers that comprise the polymer and the molecules that confine it? Can we design and build devices that mimic the functions of these nanoscale systems? The NATO Advanced Research Workshop brought together for four days in Bikal, Hungary over forty experts in experimental and theoretical biophysics, molecular biology, biophysical chemistry, and biochemistry interested in these questions. Their papers collected in this book provide insight on biological processes involving confinement and form a basis for new biotechnological applications using polymers. In his paper Edmund DiMarzio asks: What is so special about polymers? Why are polymers so prevalent in living things? The chemist says the reason is that a protein made of N amino acids can have any of 20 different kinds at each position along the chain, resulting in 20 N different polymers, and that the complexity of life lies in this variety.
Download or read book Introduction to Biopolymer Physics written by Johan R. C. van der Maarel and published by World Scientific. This book was released on 2008 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physics.
Download or read book New Directions in Guided Wave and Coherent Optics written by D.B. Ostrowsky and published by Springer. This book was released on 1971-01-31 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: As optical fiber communication systems have moved out of the laboratory and into commercial use over the past several years, the general field of guided wave and coherent optics has undergone a radical transformation. Research in optical communication has turned heavily towards single-mode technology and, totally new phenomena and applications of the existing technology, outside the communication field, have begun to proliferate. It was for this reason that we decided to organize a NATO Advanced Study Institute assembling the leading workers in this new domain, in order to define the state of the art, and, develop an idea of the new directions the field might take. The lectures and seminars presented at this Advanced Study Institute form the basis for this book. The subjects treated can be roughly grouped as : - New phenomena in optical fibers such as non-linear effects, soliton propagation and polarization conservation. - New applications of fibers, to measurements of rotation pressure, temperature etc ... and medical uses. - Advanced and exploratory work on single-mode fiber communica tion systems including the use of coherent transmission schemes and optical amplification. - Recent developments of optical information treatment based on four-wave mixing. - Integrated optical devices and technologies including bistable devices, parametric oscillators, and optical logic. In addition to these major topics, a number of national reviews and specialized seminars treating new guided wave structures and materials are included. The co-editors admit being rather pleased with the result.
Download or read book Structure and Dynamics of Hydrated Biopolymers written by Poornima Ramamohan and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Biopolymer Based Materials written by Sabu Thomas and published by John Wiley & Sons. This book was released on 2013-04-16 with total page 880 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first systematic scientific reference in the area of micro- and nanostructured biopolymer systems discusses in two volumes the morphology, structure, dynamics, properties and applications of all important biopolymers, as well as their blends, composites, interpenetrating networks and gels. Selected leading researchers from industry, academia, government and private research institutions around the globe comprehensively review recent accomplishments in the field. They examine the current state of the art, new challenges, and opportunities, discussing all the synthetic routes to the generation of both micro- and nano-morphologies, as well as the synthesis, characterization and application of porous biopolymers. An outstanding resource for anyone involved in the fi eld of eco-friendly biomaterials for advanced technologies.
Download or read book Solid State NMR Spectroscopy for Biopolymers written by Hazime Saitô and published by Springer Science & Business Media. This book was released on 2006-08-05 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: ‘‘Biopolymers’’ are polymeric materials of biological origin, including globular, membrane, and fibrous proteins, polypeptides, nucleic acids, po- saccharides, lipids, etc. and their assembly, although preference to respe- ive subjects may be different among readers who are more interested in their biological significance or industrial and/or medical applications. Nevert- less, characterizing or revealing their secondary structure and dynamics may be an equally very important and useful issue for both kinds of readers. Special interest in revealing the 3D structure of globular proteins, nucleic acids, and peptides was aroused in relation to the currently active Structural Biology. X-ray crystallography and multidimensional solution NMR sp- troscopy have proved to be the standard and indispensable means for this purpose. There remain, however, several limitations to this end, if one intends to expand its scope further. This is because these approaches are not always straightforward to characterize fibrous or membrane proteins owing to extreme difficulty in crystallization in the former, and insufficient spectral resolution due to sparing solubility or increased effective molecular mass in the presence of surrounding lipid bilayers in the latter.
Download or read book Solid State NMR Studies of Biopolymers written by Anne E. McDermott and published by John Wiley & Sons. This book was released on 2012-12-19 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: The content of this volume has been added to eMagRes (formerly Encyclopedia of Magnetic Resonance) - the ultimate online resource for NMR and MRI. The field of solid state NMR of biological samples [ssNMR] has blossomed in the past 5-10 years, and a cohesive overview of the technology is needed for new practitioners in industry and academia. This title provides an overview of Solid State NMR methods for studying structure dynamics and ligand-binding in biopolymers, and offers an overview of RF pulse sequences for various applications, including not only a systematic catalog but also a discussion of theoretical tools for analysis of pulse sequences. Practical examples of biochemical applications are included, along with a detailed discussion of the many aspects of sample preparation and handling that make spectroscopy on solid proteins successful. About EMR Handbooks / eMagRes Handbooks The Encyclopedia of Magnetic Resonance (up to 2012) and eMagRes (from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of EMR Handbooks / eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of articles from eMagRes. In consultation with the eMagRes Editorial Board, the EMR Handbooks / eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written (together with updates of some already existing articles) to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this Handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes View other eMagRes publications here
Download or read book Biomolecular Structure and Dynamics written by G. Vergoten and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomolecular Structure and Dynamics describes recent fundamental advances in the experimental and theoretical study of molecular dynamics and stochastic dynamic simulations, X-ray crystallography and NMR of biomolecules, the structure of proteins and its prediction, time resolved Fourier transform IR spectroscopy of biomolecules, the computation of free energy, applications of vibrational CD of nucleic acids, and solid state NMR. Further presentations include recent advances in UV resonance Raman spectroscopy of biomolecules, semiempirical MO methods, empirical force fields, quantitative studies of the structure of proteins in water by Fourier transform IR, and density functional theory. Metal-ligand interactions, DFT treatment of organometallic and biological systems, and simulation vs. X-ray and far IR experiments are also discussed in some detail. The book provides a broad perspective of the current theoretical aspects and recent experimental findings in the field of biomolecular dynamics, revealing future research trends, especially in areas where theoreticians and experimentalists could fruitfully collaborate.
Download or read book Modern Methods for Theoretical Physical Chemistry of Biopolymers written by Evgeni Starikov and published by Elsevier. This book was released on 2011-08-11 with total page 605 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Methods for Theoretical Physical Chemistry of Biopolymers provides an interesting selection of contributions from an international team of researchers in theoretical chemistry. This book is extremely useful for tackling the complicated scientific problems connected with biopolymers' physics and chemistry. The applications of both the classical molecular-mechanical and molecular-dynamical methods and the quantum chemical methods needed for bridging the gap to structural and dynamical properties dependent on electron dynamics are explained. Also included are ways to deal with complex problems when all three approaches need to be considered at the same time. The book gives a rich spectrum of applications: from theoretical considerations of how ATP is produced and used as ‘energy currency’ in the living cell, to the effects of subtle solvent influence on properties of biopolymers and how structural changes in DNA during single-molecule manipulation may be interpreted. · Presents modern successes and trends in theoretical physical chemistry/chemical physics of biopolymers · Topics covered are of relevant importance to rapidly developing areas in science such as nanotechnology and molecular medicine · Quality selection of contributions from renowned scientists in the field
Download or read book Biopolymer Research Trends written by Tamás S. Németh and published by Nova Publishers. This book was released on 2007 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopolymers are a special class of polymers produced by living organisms. Starch, proteins and peptides, DNA, and RNA are all examples of biopolymers, in which the monomer units, respectively, are sugars, amino acids, and nucleic acids.A major but defining difference between polymers and biopolymers can be found in their structures. Polymers, including biopolymers, are made of repetitive units called monomers. Biopolymers inherently have a well defined structure: The exact chemical composition and the sequence in which these units are arranged is called the primary structure. Many biopolymers spontaneously fold into characteristic compact shapes (see also "protein folding" as well as secondary structure and tertiary structure), which determine their biological functions and depend in a complicated way on their primary structures. Structural biology is the study of the structural properties of the biopolymers. In contrast most synthetic polymers have much simpler and more random (or statistic) structures. This book presents leading-edge research from around the world in this dynamic field.
Download or read book A Computational Study of the Conformational Structure and Dynamics of Biopolymers in Relation to Single Molecule Fluorescence Resonance Energy Transfer Measurements written by Jianyuan Shang and published by . This book was released on 2006 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structure and Property of Polymers and Biopolymers from Molecular Dynamic Simulations written by Xiaoquan Sun and published by . This book was released on 2018 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural and synthetic polymers and biopolymers have been studied for a variety of applications in food emulsion, biopharmaceutical purification, tissue engineering, and biosensor. The structure and property of polymers and biopolymers are critically important to determine their functions. Molecular dynamics (MD) simulations have a unique advantage to explore the structure and property of polymers and biopolymers from the molecular level. In the dissertation, MD simulations were conducted to study the mechanisms of various biological and chemical processes controlled by polymers and biopolymers based on real-world experimental results. Seven heptapeptides have been screened from a peptide library in our earlier study of the antibody purification. They have substantial binding affinities to the Fc fragment of IgG. In Chapter 2, the binding mechanisms between seven heptapeptides and the Fc fragment have been investigated by protein-ligand docking, free energy calculation and MD simulations. It is the first time that glycan residues are found to be the binding pocket for small ligands. The novel binding pocket is different from the CBS binding site for protein A and protein G. We also found out that, the results of free energy calculations are in good agreement with the ELISA experiments. The thermos-responsive polymer, PVCL (poly(N-vinylcaprolactam)) was grafted on the surface of a membrane as the responsive hydrophobic chromatography for the protein purification in our earlier study. In Chapter 3, significant efforts have been devoted to develop the force field parameters for PVCL. The coil-to-globule conformational transition of PVCL has been successfully observed in MD simulation for the first time. The water dynamics analysis provides significant insights into the interaction between PVCL and water molecules. The novel statistical analysis of VCL ring conformations and the distribution along backbone also elucidate the steric requirement in the coil-to-globule transition. In Chapter 4, MD simulations were conducted to investigate the biocompatibility, energetics and interaction mechanisms between the PVCL polymer chains and bovine serum albumin (BSA) in 1M NaCl and aqueous solutions. Water structures surrounding the polymer chains and BSA as well as their hydrogen bonding, electrostatic and van der Waals interactions were determined. Significant insights were obtained on the effects of polymer hydration state, polymer chain length as well as the presence of salt ions on the proteinligand interactions. A novel polymeric solid acid catalyst consisting of two polymer chains grafted on a substrate for biomass hydrolysis was successfully synthesized. A poly (styrene sulfonic acid) (PSSA) polymer chain is immobilized on a substrate and used to catalyze biomass hydrolysis. A neighboring poly (vinyl imidazolium chloride) ionic liquid (PIL) polymer chain is grafted to help solubilize lignocellulosic biomass and enhance the catalytic activity. To elucidate mechanistically the catalytic actions and further optimize its performance, interactions among the PSSA, PIL, and cellulose chains were investigated using MD simulations in Chapter 5. Moreover, the free energies surfaces for the interactions between polymer chains and cellulose substrate were determined using combined MD and Metadynamics (MTD) simulations. The research clearly demonstrate that the solvent plays a critical role in the cellulose hydrolysis reaction catalyzed by novel enzyme mimic polymeric catalysts PSSA and PIL. It is found that PSSA chain is likely to form partially dehydrated interaction with cellulose in both aqueous and [EMIM]Cl solutions. PIL plays an important role to prevent the completely dehydrated interactions and facilitate partially dehydrated interaction between PSSA and cellulose chains.
Download or read book Dynamics Structure and Function of Biological Macromolecules written by Oleg Jardetzky and published by IOS Press. This book was released on 2001 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: A collection of articles looking at modern structural biology, summarizing the applications of physical methods - such as x-ray diffraction, high resolution nuclear magnetic resonance and molecular dynamics - to the study of protein structure and dynamics. There is a review of contemporary thoughts within the field, looking at the mechanisms of alloateric transitions and allosteric control, the transmission of information within protein structures and the role of dynamics in determining the specificity of protein - ligand interactions. There is also a look at future innovations.
Download or read book Biopolymers at Interfaces written by Martin Malmsten and published by Taylor & Francis US. This book was released on 1998 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on physiochemical aspects, this work provides an overview of biopolymer interfacial behaviour, advancing current understanding of the importance of protein adsorption in biophysical and biochemical processes, as well as the relevance of such phenomena in biomedicine. The text addresses fundamental aspects of biopolymer interfacial behaviour, such as adsorption kinetics, adsorbed layer structure and dynamics, interfacial orientation, effects of self-assembly on protein adsorption, interactions between biopolymer layers, and interfacial exchange.
Download or read book Biopolymer Chemistry written by Olav Smidsrød and published by Tapir Academic Press. This book was released on 2008 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book contains a description of the chemical structure of biological macromolecules, their size and shapes (conformation), and how the structure and the conformation determine the physical properties of such molecules. This book discusses the relationships between the chemical and physical properties of such molecules and their technological and bio-medical properties. It is designed for second or third year bachelor's students in chemistry or physics, and for first year students in master's programmes in biochemistry, biotechnology, glycobiology and bio-nanotechnology. The book will be an asset for programmes for polymer chemistry and technology. Professor Emeritus Olav SmidsrÃ?Â, d, Dr. techn. is a central figure at the Department of Biotechnology, Norwegian University of Science and Technology, where he also was the director of the Norwegian Biopolymer Laboratory for 20 years. Professor SmidsrÃ?Â, d has published 200 scientific papers in international journals, and was an editorial board member for three journals. He holds 15 patents dealing with the production and bio-medical uses of biopolymers. He was granted knighthood to the order of St. Olav and holds many academic distinctions for his research work. Associate Professor StÃ?Â, rker Moe, Dr. ing. works at the Department of Chemical Engineering at the Norwegian University of Science and Technology where he is an expert in industrial wood chemistry. He has published numerous papers in a wide range of topics related to wood chemistry, such as cellulose chemistry, and hemicellulose behaviour in pulping processes and lignin chemistry.