Download or read book Steroid Hormones and the T Cell Cytokine Profile written by G.A.W. Rook and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fact that certain adrenal steroid hormones are immunosuppresive and anti-inflammatory has been known for many years. However, new information has led to the possibility of immunoregulatory steroids being used by physicians in novel ways. This book details these new therapies which could revolutionise the treatment of certain Th2-mediated diseases such as asthma. It provides an overview of these new concepts, starting with how the immune response triggers adrenal steroid production and finishing with in vivo models of infection and autoimmunity that demonstrate the clinical importance of these new insights into the physiological control of glucocorticoid function. The information contained is mostly very new, some of it previously unpublished, and will open up new horizons for immunologists, endocrinologists, physiologists, cell biologists and clinicians.
Download or read book Endocrine Immunology written by W. Savino and published by Karger Medical and Scientific Publishers. This book was released on 2017-02-28 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last decades, several in vitro and in vivo studies have revealed the existence of a very complex network between the neuroendocrine and immune system. Important molecular mechanisms underlying these interactions, in both physiological and pathological conditions, have also been described. Indeed, hormones play a pivotal role in the development and functional regulation of the immune system – both innate and acquired responses. Immune system cells present specific hormone receptors and themselves produce some hormones, thus influencing hormone secretion. More recently, the modulation of hormone secretion has been attempted for treating associated autoimmune disorders, further supporting the strong interplay between the endocrine and immune system. Distinguished experts, who have published extensively in their fields, have contributed comprehensive chapters to this volume. The focus is on the various aspects of endocrine-neuro-immune connections, providing an updated panorama - from basics to clinical applications - of current knowledge and still debated issues.
Download or read book Principles of Cancer Biotherapy written by Robert K. Oldham and published by Springer Science & Business Media. This book was released on 2009-08-29 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the time of the first edition of Principles of Cancer Biotherapy in 1987, this book represented the first comprehensive textbook on biological therapy. In 1991, when the second edition was published, there was still some doubt on the part of many oncologists and cancer researchers as to the therapeutic value of these new approaches. By 2003 and the fourth edition, it was generally agreed that biopharmaceuticals were producing major opportunities for new cancer therapies. Cancer biotherapy has now truly matured into the fourth modality of cancer treatment. This fifth revised edition describes the tremendous progress that has been made in recent years using biologicals in cancer treatment. This book summarizes an evolving science and a rapidly changing medical practice in biotherapy. In this new millennium, it is now possible to envision a much more diversified system of cancer research and treatment that will afford greater opportunities for a patient’s personalized cancer treatment. This was first envisioned in the 1987 initial edition of this textbook and is now a “new” and popular approach to cancer treatment. Some forms of cancer biotherapy use the strategy of tumor stabilization and control through continued biological therapy, akin to the use of insulin in the treatment of diabetes. This textbook illustrates new methods of thinking and new strategies for control of cancer. It is always difficult to move from past dogma to future opportunity, but this fifth edition of Principles of Cancer Biotherapy illustrates why it is so important to the patients for researchers and clinicians to explore and quickly apply these new opportunities in cancer biotherapy.
Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-02-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.
Download or read book Handbook on Immunosenescence written by Tamas Fulop and published by Springer Science & Business Media. This book was released on 2009-02-27 with total page 1693 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative handbook covers all aspects of immunosenescence, with contributions from experts in the research and clinical areas. It examines methods and models for studying immunosenescence; genetics; mechanisms including receptors and signal transduction; clinical relevance in disease states including infections, autoimmunity, cancer, metabolic syndrome, neurodegenerative diseases, frailty and osteoporosis; and much more.
Download or read book Menopause written by Rogerio A. Lobo and published by Academic Press. This book was released on 2000-05-22 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Menopause: Biology and Pathobiology is a comprehensive volume covering all aspects of the biology, anatomy, physiology, pathobiology, and pharmacology of menopause, as well as its diagnosis and management. The book is divided into four sections: Basic Biology, Epidemiology, Menopausal Systems Pathophysiology, and Intervention. Basic Biology covers such fundamentals as ovarian anatomy and physiology, mechanisms of steroid hormone action, chronobiological effects, and premature menopause. Epidemiology includes, among others, chapters on methodology challenges in the study of menopause, how to distinguish the effects of age from those of menopause, and a discussion of the key differences in demographics, environmental factors, and ethnicity in the menopause experience. The Pathophysiology section contains chapters on menopause and its various effects on the body, including sexuality, skin, brain, the cardiovascular system, cancers, and mood. The final section includes detailed chapters on intervention and management techniques, with topics including alternative therapies to hormone replacement, exercise, and estrogens and osteoporosis. * Well-referenced to allow easy look up of anything related to menopause * Presents the latest thinking on basic science and clinical topics * Exposes what the current gaps in our knowledge are * Presents current expert opinions
Download or read book Contact Dermatitis written by Peter J. Frosch and published by Springer Science & Business Media. This book was released on 2006-06-07 with total page 1127 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is an unusual event for a textbook covering such a national and international networks and the use of highly specialized field as contact dermatitis to be standardized methodology, a highly differentiated published in its fourth edition within a time period picture can now be painted; we know the major p- of 13 years. When the European and Environmental fessions at risk, as well as the influences of age and Contact Dermatitis Research Group was founded in various cofactors. This is a solid basis for preventive 1985,one of the major goals was to edit a textbook of measures. A new allergen, described in one center, high scientific standard written by renown experts can now be tested on a large scale in a short time and keep it regularly updated. The greatest danger period. If the data evaluation shows an unacceptably for a textbook is to become outdated – then it stays high rate of sensitization in the exposed population, on the bookshelf and is rarely consulted. The contin- regulatory measures will be undertaken to protect uous flow of new medicaments, the fascinating the consumer. A recent example is the “methyldib- improvements in diagnostic image analysis and ever- mo glutaronitrile story. ” changing operative procedures are the reasons for These and other issues of importance are covered considerable knowledge deficits in old textbooks, in depth in the newest edition of this textbook.
Download or read book The Granulomatous Disorders written by D. Geraint James and published by Cambridge University Press. This book was released on 1999-09-09 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative account of the granulomatous disorders provides a comprehensive overview of this complex group of diseases. Collectively, these disorders can present a bewildering array of symptoms, affecting all the body systems. This volume takes full account of recent advances in our knowledge of the molecular biology and immunology of these disorders, and casts fresh light on their diagnosis and treatment. This timely publication is organised to include chapters focused on causative agents and those addressing affected body systems. Highly illustrated throughout, including numerous colour plates, it encompasses and integrates the very latest science, pathology and practical clinical advice. Compiled by international authorities with chapters which combine the expertise of both a pathologist and clinician, it is sure to become an essential source of reference for a very wide readership including infectious disease specialists, immunologists, pathologists, radiologists, ophthalmologists and general physicians.
Download or read book Perimenopause written by Rogerio A. Lobo and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here, the editor, Rogerio Lobo, has assembled an internationally recognized group of reproductive endocrinologists to address perimenopause -- the time both before and after the last menses -- and its attendant decline in ovarian function, as well as the clinical issues and therapeutic options for women during this period.
Download or read book Trending Topics in Multiple Sclerosis written by Alina Gonzalez-Quevedo and published by BoD – Books on Demand. This book was released on 2016-09-08 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple sclerosis (MS) is a chronic inflammatory disease characterized by progressive demyelination and neurodegeneration of the central nervous system (CNS), constituting the most common demyelinating disease of the CNS in humans. Although intensive research over many decades has unveiled many pathophysiological mechanisms in the development of MS, the cause is still unknown. Nevertheless, it does seem clear that genetic susceptibility and environmental factors play crucial roles. Trending Topics in Multiple Sclerosis is a book that provides an insight into some of the main problems currently debated in this area of research, focusing on topics that deal with genetic and environmental risk factors, pathophysiological mechanisms, neurocognitive findings, and neuroprotective strategies.
Download or read book Textbook of Contact Dermatitis written by R.J.G. Rycroft and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 1068 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition is an update on every conceivable aspect of the modern-day management of contact dermatitis. Both irritant and allergic contact dermatitis are covered clearly and comprehensively, special emphasis being given to occupational aspects as well as to prevention, diagnosis and treatment. The Textbook also covers epidemiology, the computerization of patch test data and patient information systems, noninvasive bioengineering measurement techniques, methods of skin testing other than patch testing, the histopathology of both irritant and all ergic contact dermatitis, and subjective reactions.
Download or read book Sex Hormones and Immunity to Infection written by Sabra L. Klein and published by Springer Science & Business Media. This book was released on 2009-10-22 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why sex matters Among human and nonhuman animals, the prevalence and intensity of infection typically is higher in males than females and may reflect differences in exposure as well as susceptibility to pathogens. Elevated immunity among females is a double-edged sword in which it is beneficial against infectious diseases but is detrimental in terms of increased development of autoimmune diseases. The present book critically reviews the evolutionary origin and the functional mechanisms responsible for sexual dimorphism in response to infection. It emphasizes the value of examining responses in both males and females to improve our understanding about host-pathogen interactions in both sexes. The contributors are experts in their specific disciplines which range from microbiology and immunology to genetics, pathology, and evolutionary biology. The book aims at bringing insight to the treatment and management of infectious diseases; it delineates areas where knowledge is lacking and highlights future avenues of research.
Download or read book Diagnosis and Management of Ovarian Disorders written by Albert Altchek and published by Elsevier. This book was released on 2003-09-04 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine
Download or read book Dehydroepiandrosterone DHEA written by Mohammed Kalimi and published by Walter de Gruyter. This book was released on 2011-07-13 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Immunoendocrinology in Health and Disease written by Vincent Geenen and published by CRC Press. This book was released on 2004-08-30 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the first comprehensive references dealing specifically with this new field of interdisciplinary research in medicine, Immunoendocrinology in Health and Disease offers a full scientific picture of where the immune and neuroendocrine systems intersect-placing current understanding of system components, mechanisms, and functions side by side w
Download or read book Handbook of Multiple Sclerosis written by Stuart D. Cook and published by CRC Press. This book was released on 2001-03-30 with total page 685 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reporting on the latest advances made in treating multiple sclerosis (MS) and continuing the high standards set by earlier editions, the Handbook of Multiple Sclerosis, Third Edition examines a wide range of topics from etiology to treatment options. Analyzes recent developments in the natural history, immunopathology, lesion evolution, and
Download or read book Treatment of Chronic Fatigue Syndrome in the Antiviral Revolution Era written by Roberto Patarca-Montero and published by Routledge. This book was released on 2014-01-14 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: Are viruses the key to understanding this mysterious, devastating disease?Chronic fatigue syndrome (CFS) causes great suffering, not least because its etiology is so poorly understood. Treatment of Chronic Fatigue Syndrome in the Antiviral Revolution Era offers proof that viruses may be direct or indirect causes of the disease. Therefore the new antiviral agents, the first fruits of the expanding genomics revolution, may be of use in treating this disorder.In recent years, innovative hypotheses on disease have challenged conventional medical wisdom. New studies give powerful evidence that pathological processes as diverse as atherosclerosis and autoimmune disease may be of viral origin. Treatment of Chronic Fatigue Syndrome in the Antiviral Revolution Era takes these ideas a step further and applies them to CFS, offering fresh possibilities for treating this debilitating disease.This breakthrough book presents the latest research on antiviral agents, including: the scientific rationale for their use in CFS the historical evolution of these drugs results of clinical trials new lines of research It also offers updates on specific drugs and treatments, including: Acyclovir, Ampligen, Imunovir (Inosine Pranobex), and 2CVV vaccines against Epstein-Barr virus, influenza, staphylococcus, and stealth virus Interferon-Alpha ginseng and other herb-based antivirals . . . and many more! Treatment of Chronic Fatigue Syndrome in the Antiviral Revolution Era is an essential resource for physicians, researchers, virologists, and patient advocates, as well as for anyone who is trying to obtain the best possible treatment for CFS.
