Download or read book Stem Cells Research Compendium written by Prasad S. Koka and published by Nova Science Publishers. This book was released on 2014-05-14 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Compendium of Recent Research on Stem Cell Based Therapy for Covid 19 written by Abdelkrim Hmadcha and published by Frontiers Media SA. This book was released on 2022-01-28 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Stem Cell Research written by David E. Newton and published by Facts on File. This book was released on 2007 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most controversial debates in scientific research today focuses on the use of embryonic stem cells in medical research. Recent discoveries suggest that stem cells exist within embryos and are even more plastic than adult cells, meaning that they are capable of developing into virtually any type of cell found in a living body. This discovery has raised the possibility of using embryonic stem cells for the treatment of a host of medical conditions, including Parkinson's and Alzheimer's diseases, spinal cord injuries, strokes, burns, heart disease, diabetes, osteoarthritis, and rheumatoid arthritis. In each instance, the transplantation of embryonic stem cells into the patient's body is expected to result in the growth of healthy new tissue or organs that have been damaged by the disease being treated. However, opponents of this scientific procedure doubt the validity of the scientific premises behind these therapeutic uses and oppose the destruction of human embryos for further research. Current federal law and regulations allow researchers to use federal funds to conduct some types of stem cell research using adult stem cells, but not embryonic stem cells, which significantly slows the progress of this possibly life-altering medical study. Exploring the political and ethical issues associated with this area of study, Stem Cell Research gives students and general readers alike a comprehensive look at both the science and the controversy surrounding this groundbreaking research. This first-stop reference provides clear and essential information needed to define, understand, and research this important issue objectively. Covering court cases, legislation, and relevant policies, this volume also includes a chronology; a glossary; a guide to further research; an annotated bibliography, an integral part of the Library in a Book series; appendixes; as well as an index.

Download or read book The SAGE Encyclopedia of Stem Cell Research written by Eric E. Bouhassira and published by SAGE Publications. This book was released on 2015-06-15 with total page 3560 pages. Available in PDF, EPUB and Kindle. Book excerpt: The SAGE Encyclopedia of Stem Cell Research, Second Edition is filled with new procedures and exciting medical breakthroughs, including executive orders from the Obama administration reversing barriers to research imposed under the Bush administration, court rulings impacting NIH funding of research based on human embryonic stem cells, edicts by the Papacy and other religious leaders, and the first success in cloning human stem cells. Stem cell biology is clearly fueling excitement and potential in traditional areas of developmental biology and in the field of regenerative medicine, where they are believed to hold much promise in addressing any number of intractable medical conditions. This updated second edition encyclopedia will expand on information that was given in the first edition and present more than 270 new and updated articles that explore major topics in ways accessible to nonscientists, thus bringing readers up-to-date with where stem cell biology stands today, including new and evolving ethical, religious, legal, social, and political perspectives. This second edition reference work will serve as a universal resource for all public and academic libraries. It is an excellent foundation for anyone who is interested in the subject area of stem cell biology. Key Features: Reader’s Guide, Further Readings, Cross References, Chronology, Resource Guide, Index A Glossary will elucidate stem cell terminology for the nonscientist Statistics and selected reprints of major journal articles that pertain to milestones achieved in stem cell research Documents from Congressional Hearings on stem cells and cloning Reports to the President’s Council on Bioethics, and more

Download or read book Stem Cells and Cancer written by Rebecca G. Bagley and published by Springer Science & Business Media. This book was released on 2009-04-20 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significance of Stem Cells to Tumor Development Cancer stem cells remain a controversial topic and the criteria that define cancer stem cells are continuing to evolve. A recent surge in stem cell research has ignited a field of discovery into many human diseases including diabetes, neuropathologies, and cancer. By replacing specific differentiated cells that have either been lost or died, stem cell therapy proves to be a very promising approach to the treatment of many debilitating diseases. Though stem cells may provide therapeutic benefit under certain conditions, they are also often implicated in the initiation, progression, and therapeutic resistance of malignant disease. This first edition of Stem Cells and Cancer is intended to give a current perspective on the role of stem cells in cancer and strategies for novel therapies directed toward tumor stem cells. The current cancer stem cell hypothesis is presented in several chapters with distinctions made between the hierarchical and stochastic models of tumor cell development. "Stemness," self-renewal, pluripotency, clonality, and tumorigenicity are important concepts applied towards defining cancer stem cells. Signaling pathways such as Wnt, Sonic Hedgehog, Notch, and Bmi-1 that are involved in differentiation, proliferation, and survival are implicated in the malignant process. Additional chapters address the identification of cancer stem cell populations through the evaluation of molecular markers such as CD133, CD44, and CD24, for example, or by Hoescht dye exclusion to recognize ‘side populations.’ Mesenchymal and hematopoietic stem cells are described as well as mouse models that are employed to elucidate the properties and functionality of stem cells in cancer and the stem cell niche. This book encompasses a wide variety of human cancers that include but are not limited to leukemia, gliomas, breast, and prostate cancers. Resistance to conventional therapies, genetic versus epigenetic changes that affect therapeutic response and strategies to prevent disease recurrence are challenges have been incorporated into this volume. Stem Cells and Cancer represents a compendium of cutting edge research by experts in the field and will be instrumental in the study of this intriguing line of investigation for many years to come. Rebecca Bagley is a senior scientist at Genzyme Corporation and has worked in the biotechnology industry for 20 years with degrees in biology from Wellesley College and Harvard University. Her expertise in drug development spans a wide range of approaches including immunotherapies, gene and protein therapies, and small molecule delivery with publications in journals such as Molecular Cancer Therapeutics, Cancer Research, and Microvascular Research . Her current research focuses on stem cells, tumor vasculature, and target validation. Dr. Beverly A. Teicher is Vice President of Oncology Research at Genzyme Corporation. Dr. Teicher completed a PhD in Bioorganic Chemistry at the Johns Hopkins University and postdoctoral training at Yale University School of Medicine. Dr. Teicher joined Dana-Farber Cancer Institute as an Assistant Professor of Pathology and rose to Associate Professor of Medicine and Radiation Therapy, Harvard Medical School at Dana-Farber Cancer Institute and Joint Center for Radiation Therapy. Dr. Teicher is an active member of the international scientific community having authored or co-authored more than 400 scientific publications. She has edited eight books, is senior editor for the journal Clinical Cancer Research and is series editor for the Cancer Drug Discovery and Development book series.

Download or read book Essentials of Stem Cell Biology written by Robert Lanza and published by Elsevier. This book was released on 2005-11-22 with total page 580 pages. Available in PDF, EPUB and Kindle. Book excerpt: This abridged version of the bestselling reference Handbook of Stem Cells, Two-Volume Set attempts to incorporate all the essential subject matter of the original two-volume edition in a single volume. The material has been reworked in an accessible format suitable for students and general readers interested in following the latest advances in stem cells, including full color presentation throughout. Although some extra language and chapters have been deleted, rigorous effort has been made to retain from the original two-volume set the material pertinent to the understanding of this exciting area of biology. The organization of the book remains largely unchanged, combining the prerequisites for a general understanding of adult and embryonic stem cells; the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations; as well as a presentation by the world's experts of what is currently known about each specific organ system. * Full-color presentation througout * Each chapter begins with 3-5 defined glossary terms, and all of the terms are collected in a comprehensive list within the book * References have been eliminated - now there are about 10 bibliographic entries per chapter

Download or read book Stem Cells Research Compendium written by Prasad S. Koka and published by Nova Publishers. This book was released on 2008 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two broad categories of mammalian stem cells exist: embryonic stem cells, derived from blastocysts, and adult stem cells, which are found in adult tissues. In a developing embryo, stem cells are able to differentiate into all of the specialised embryonic tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing specialised cells. As stem cells can be readily grown and transformed into specialised tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed. In particular, embryonic cell lines, autologous embryonic stem cells generated therapeutic cloning, and highly plastic adult stem cells from the umbilical cord blood or bone marrow are touted as promising candidates. Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, autoimmune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book presents leading research from around the world in this field which is of interest to so many and presents so many hopes.

Download or read book Human Stem Cell Manual written by Suzanne E. Peterson and published by Academic Press. This book was released on 2023-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Stem Cell Manual: A Laboratory Guide, Third Edition is a comprehensive compilation of "methods that work” for deriving, characterizing, and differentiating hPSCs, written by the researchers who developed and tested the methods and use them every day in their laboratories. The manual is much more than a collection of recipes; it is an extraordinary laboratory guide for both experienced stem cell research and those just beginning to use stem cells in their work. The editors chose a range of subjects that are critical to stem cell research worldwide and provide introductions for each chapter which discuss the importance of the information in the broad context of stem cell biology. Also included are chapters on the legal and ethical issues that affect stem cell research and researchers. Cross references in each chapter guide the reader to other chapters that may be of interest and emphasize the interrelatedness of the information in the book as a whole. New coverage includes disease modelling, drug development, and other cell therapy applications. The manual is written by foremost experts from around the world for anyone doing research in the field of stem cell biology.

Download or read book Culture of Human Stem Cells written by R. Ian Freshney and published by Wiley-Liss. This book was released on 2007-06-22 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects the most effective and cutting-edge methods and protocols for deriving and culturing human embryonic and adult stem cells—in one handy resource. This groundbreaking book follows the tradition of previous books in the Culture of Specialized Cells Series—each methods and protocols chapter is laid out exactly like the next, with stepwise protocols, preceded by specific requirements for that protocol, and a concise discussion of methods illustrated by data. The editors describe a limited number of representative techniques across a wide spectrum of stem cells from embryonic, newborn, and adult tissue, yielding an all-encompassing and versatile guide to the field of stem cell biology and culture. The book includes a comprehensive list of suppliers for all equipment used in the protocols presented, with websites available in an appendix. Additionally, there is a chapter on quality control, and other chapters covering legal and ethical issues, cryopreservation, and feeder layer culture. This text is a one-stop resource for all researchers, clinical scientists, teachers, and students involved in this crucial area of study.

Download or read book Encyclopedia of Stem Cell Research written by Alexander L. Greene and published by Nova Biomedical Books. This book was released on 2012-06-05 with total page 1584 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents important research advances in the study of stem cell research, as well as stem cell applications in diseases; stem cell transplantation; and pluripotent stem cells. Topics discussed herein include stem cell therapy for Alzheimer's disease; cancer stem cells and ncRNAs; stem cell applications in diabetes; image-guided stem cell therapy; cancer stem cells; stem cell transplantation; vascular tissue engineering; bone marrow-derived stem cells; and stem cell plasticity.

Download or read book Stem Cells For Dummies written by Lawrence S.B. Goldstein and published by For Dummies. This book was released on 2010-01-05 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first authoritative yet accessible guide to this controversial topic Stem Cell Research For Dummies offers a balanced, plain-English look at this politically charged topic, cutting away the hype and presenting the facts clearly for you, free from debate. It explains what stem cells are and what they do, the legalities of harvesting them and using them in research, the latest research findings from the U.S. and abroad, and the prospects for medical stem cell therapies in the short and long term. Explains the differences between adult stem cells and embryonic/umbilical cord stem cells Provides both sides of the political debate and the pros and cons of each side's opinions Includes medical success stories using stem cell therapy and its promise for the future Comprehensive and unbiased, Stem Cell Research For Dummies is the only guide you need to understand this volatile issue.

Download or read book Fundamentals of the Stem Cell Debate written by Kristen Renwick Monroe and published by Univ of California Press. This book was released on 2008 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: "What the editors have managed to accomplish with Fundamentals of the Stem Cell Debate is very significant. The book is well-informed, sophisticated, and attends to the moral and scientific complexities of stem cell research, rather than sweeping them under the rug. This book encompasses the complexities without sacrificing the other main virtue of the collection: to definitively illuminate the debate for all."—Jason Scott Robert, author of Embryology, Epigenesis, & Evolution: Taking Development Seriously

Download or read book Proteoglycans in Stem Cells written by Martin Götte and published by Springer Nature. This book was released on 2021-06-07 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a state-of-the-art compendium on the role of proteoglycans and glycosaminoglycans during development and in cancer. It also suggests directions for novel therapeutic and biotechnological applications in stem cell biology. Proteoglycans and glycosaminoglycans, as part of the extracellular matrix, are multifunctional modulators of growth factor, cytokine, integrin and morphogen signaling, which determine both self-renewal, senescence and/or differentiation of stem cells during development. Since proteoglycans modulate cell adhesion and migration they are important organizers of the extracellular matrix within the proper stem cell niche. A malfunctioning of proteoglycans and glycosaminoglycans contributes to the cancer stem cell phenotype, which is linked to therapeutic resistance and recurrence in malignant disease. This book is essential reading for anyone interested in the extracellular matrix and its role in development. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Download or read book White House Studies Compendium written by Robert W. Watson and published by Nova Publishers. This book was released on 2007 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: " ... brings together piercing analyses of the American presidency - dealing with both current issues and historical events. The compendia consists of the combined and rearranged issues of [the journal] "White House Studies" with the addition of a comprehensive subject index."--Preface.

Download or read book Stem Cells From Basic Research to Therapy written by Federico Calegari and published by CRC Press. This book was released on 2014-02-07 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first volume of Stem Cells deals with the fundamental principles that govern embryonic and somatic stem cell biology. Historically, the identification and characterization of such pathways and general rules of stemness occurred during embryonic development and Volume I reflects this with topics spanning cell cycle regulation, epigenetics, and asymmetric cell division in a number of organ systems from planarian to human. Three specific sections discuss i) Basic Stem Cell Biology, ii) Tissue Formation During Development, and iii) Model Organisms with particular emphasis on those more relevant for biomedical research and, thus, leading to the topics addressed in Volume II.

Download or read book Exosomes written by Larry Edelstein and published by Academic Press. This book was released on 2019-10-16 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomes in the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medical disciplines, as well as their role in cell-cell communication. It is intended to serve as a reference source for clinicians, physicians, and research scientists who wish to gain insight into the most recent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine since antibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is a major breakthrough in our understanding of how cells function. Provides readers with a broad and timely overview of exosomes in health and disease, closing with a thought-provoking chapter on transgenerational inheritance, Darwin and Lamarck. Summarizes the most recent laboratory and clinical findings on exosomes across numerous medical disciplines, thereby offering readers a broad-ranging and solid foundation for prospective investigative efforts Twenty-one chapters authored by a global team of peer-acknowledged experts, each representing a key medical disciplineProvides readers with a broad and timely overview of exosomes in health and disease, closing

Download or read book Mesenchymal Stem Cell Derived Exosomes written by Yaoliang Tang and published by Academic Press. This book was released on 2015-09-02 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mesenchymal stem cell-derived exosomes are at the forefront of research in two of the most high profile and funded scientific areas – cardiovascular research and stem cells. Mesenchymal Stem Cell Derived Exosomes provides insight into the biofunction and molecular mechanisms, practical tools for research, and a look toward the clinical applications of this exciting phenomenon which is emerging as an effective diagnostic. Primarily focused on the cardiovascular applications where there have been the greatest advancements toward the clinic, this is the first compendium for clinical and biomedical researchers who are interested in integrating MSC-derived exosomes as a diagnostic and therapeutic tool. Introduces the MSC-exosome mediated cell-cell communication Covers the major functional benefits in current MSC-derived exosome studies Discusses strategies for the use of MSC-derived exosomes in cardiovascular therapies