Download or read book Statistical Thinking in Epidemiology written by Yu-Kang Tu and published by CRC Press. This book was released on 2016-04-19 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: While biomedical researchers may be able to follow instructions in the manuals accompanying the statistical software packages, they do not always have sufficient knowledge to choose the appropriate statistical methods and correctly interpret their results. Statistical Thinking in Epidemiology examines common methodological and statistical problems

Download or read book Statistical Thinking in Clinical Trials written by Michael A. Proschan and published by CRC Press. This book was released on 2021-11-24 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Thinking in Clinical Trials combines a relatively small number of key statistical principles and several instructive clinical trials to gently guide the reader through the statistical thinking needed in clinical trials. Randomization is the cornerstone of clinical trials and randomization-based inference is the cornerstone of this book. Read this book to learn the elegance and simplicity of re-randomization tests as the basis for statistical inference (the analyze as you randomize principle) and see how re-randomization tests can save a trial that required an unplanned, mid-course design change. Other principles enable the reader to quickly and confidently check calculations without relying on computer programs. The `EZ’ principle says that a single sample size formula can be applied to a multitude of statistical tests. The `O minus E except after V’ principle provides a simple estimator of the log odds ratio that is ideally suited for stratified analysis with a binary outcome. The same principle can be used to estimate the log hazard ratio and facilitate stratified analysis in a survival setting. Learn these and other simple techniques that will make you an invaluable clinical trial statistician.

Download or read book Statistical Epidemiology written by Graham R. Law and Shane W. Pascoe and published by CABI. This book was released on 2012 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistics are a vital skill for epidemiologists and form an essential part of clinical medicine and public health. This textbook introduces students to statistical epidemiology methods in a carefully structured and accessible format. With clearly defined learning outcomes, the suggested chapter orders can be tailored to the needs of students at both undergraduate and graduate level from a range of academic backgrounds. The book covers study design, measuring disease, bias, error, analysis and modelling and is illustrated with figures, focus boxes, study questions and examples applicable to ev.

Download or read book Statistics for Epidemiology written by Nicholas P. Jewell and published by CRC Press. This book was released on 2003-08-26 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical ideas have been integral to the development of epidemiology and continue to provide the tools needed to interpret epidemiological studies. Although epidemiologists do not need a highly mathematical background in statistical theory to conduct and interpret such studies, they do need more than an encyclopedia of "recipes." Statistics for Epidemiology achieves just the right balance between the two approaches, building an intuitive understanding of the methods most important to practitioners and the skills to use them effectively. It develops the techniques for analyzing simple risk factors and disease data, with step-by-step extensions that include the use of binary regression. It covers the logistic regression model in detail and contrasts it with the Cox model for time-to-incidence data. The author uses a few simple case studies to guide readers from elementary analyses to more complex regression modeling. Following these examples through several chapters makes it easy to compare the interpretations that emerge from varying approaches. Written by one of the top biostatisticians in the field, Statistics for Epidemiology stands apart in its focus on interpretation and in the depth of understanding it provides. It lays the groundwork that all public health professionals, epidemiologists, and biostatisticians need to successfully design, conduct, and analyze epidemiological studies.

Download or read book Intuitive Biostatistics written by Harvey Motulsky and published by Oxford University Press, USA. This book was released on 2014 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Thoroughly revised and updated, the second edition of Intuitive Biostatistics retains and refines the core perspectives of the previous edition: a focus on how to interpret statistical results rather than on how to analyze data, minimal use of equations, and a detailed review of assumptions and common mistakes. Intuitive Biostatistics, Completely Revised Second Edition, provides a clear introduction to statistics for undergraduate and graduate students and also serves as a statistics refresher for working scientists. New to this edition: Chapter 1 shows how our intuitions lead us to misinterpret data, thus explaining the need for statistical rigor. Chapter 11 explains the lognormal distribution, an essential topic omitted from many other statistics books. Chapter 21 contrasts testing for equivalence with testing for differences. Chapters 22, 23, and 40 explore the pervasive problem of multiple comparisons. Chapters 24 and 25 review testing for normality and outliers. Chapter 35 shows how statistical hypothesis testing can be understood as comparing the fits of alternative models. Chapters 37 and 38 provide a brief introduction to multiple, logistic, and proportional hazards regression. Chapter 46 reviews one example in great depth, reviewing numerous statistical concepts and identifying common mistakes. Chapter 47 includes 49 multi-part problems, with answers fully discussed in Chapter 48. New "Q and A" sections throughout the book review key concepts"--Provided by publisher.

Download or read book Medical Uses of Statistics written by John C. Bailar and published by John Wiley & Sons. This book was released on 2012-01-10 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: A new edition of the classic guide to the use of statistics in medicine, featuring examples from articles in the New England Journal of Medicine Medical Uses of Statistics has served as one of the most influential works on the subject for physicians, physicians-in-training, and a myriad of healthcare experts who need a clear idea of the proper application of statistical techniques in clinical studies as well as the implications of their interpretation for clinical practice. This Third Edition maintains the focus on the critical ideas, rather than the mechanics, to give practitioners and students the resources they need to understand the statistical methods they encounter in modern medical literature. Bringing together contributions from more than two dozen distinguished statisticians and medical doctors, this volume stresses the underlying concepts in areas such as randomized trials, survival analysis, genetics, linear regression, meta-analysis, and risk analysis. The Third Edition includes: Numerous examples based on studies taken directly from the pages of the New England Journal of Medicine Two added chapters on statistics in genetics Two new chapters on the application of statistical methods to studies in epidemiology New chapters on analyses of randomized trials, linear regression, categorical data analysis, meta-analysis, subgroup analyses, and risk analysis Updated chapters on statistical thinking, crossover designs, p-values, survival analysis, and reporting research results A focus on helping readers to critically interpret published results of clinical research Medical Uses of Statistics, Third Edition is a valuable resource for researchers and physicians working in any health-related field. It is also an excellent supplemental book for courses on medicine, biostatistics, and clinical research at the upper-undergraduate and graduate levels. You can also visit the New England Journal of Medicine website for related information.

Download or read book Medical Illuminations written by Howard Wainer and published by Oxford University Press, USA. This book was released on 2014 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirteen contemporary medical topics are used to illustrate how modern tools of statistical thinking and statistical graphics can illuminate them. The book aims to solve some vexing problems that seem perplexing, and make the problems and their solutions clear for the general reader in order to gain a greater understanding of our complex world.

Download or read book Statistical Methods in Epidemiologic Research written by Ray M. Merrill and published by Jones & Bartlett Publishers. This book was released on 2016 with total page 944 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers all the core topics, such as digital logic, data representation, machine-level language, general organization, and much more.

Download or read book Modern Methods for Epidemiology written by Yu-Kang Tu and published by Springer Science & Business Media. This book was released on 2012-05-22 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Routine applications of advanced statistical methods on real data have become possible in the last ten years because desktop computers have become much more powerful and cheaper. However, proper understanding of the challenging statistical theory behind those methods remains essential for correct application and interpretation, and rarely seen in the medical literature. Modern Methods for Epidemiology provides a concise introduction to recent development in statistical methodologies for epidemiological and biomedical researchers. Many of these methods have become indispensible tools for researchers working in epidemiology and medicine but are rarely discussed in details by standard textbooks of biostatistics or epidemiology. Contributors of this book are experienced researchers and experts in their respective fields. This textbook provides a solid starting point for those who are new to epidemiology, and for those looking for guidance in more modern statistical approaches to observational epidemiology. Epidemiological and biomedical researchers who wish to overcome the mathematical barrier of applying those methods to their research will find this book an accessible and helpful reference for self-learning and research. This book is also a good source for teaching postgraduate students in medical statistics or epidemiology.

Download or read book Advanced Medical Statistics written by Ying Lu and published by World Scientific Publishing Company Incorporated. This book was released on 2003 with total page 1101 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ch. 1. History of statistical thinking in medicine / Tar Timothy Chen -- ch. 2. Evaluation of diagnostic test's accuracy in the presence of verification bias / Xiao-Hua Zhou -- ch. 3. Statistical methods for dependent data / Feng Chen -- ch. 4. Statistics used in quality control, quality assurance, and quality improvement in radiological studies / Ying Lu and Shoujun Zhao -- ch. 5. Cost-effectiveness analysis and evidence-based medicine / Jianli Li -- ch. 6. Quality of life: issues concerning assessment and analysis / Ji-Qian Fang and Yuantao Hao -- ch. 7. Meta-analysis / Xuyu Zhuo ... [et al.] -- ch. 8. Describing data, variability and over-dispersion in medical research / Ming Tan -- ch. 9. Time series analysis and its applications in medical sciences / Jinxi Zhang, Yingdong Zheng and Dejian Lai -- ch.10. Applications of statistical methods in medical imaging / Jesse S. Jin -- ch.11. Statistics in pharmacology and pre-clinical studies / Tze Leung Lai, Mei-Chiung Shin and Guangrui Zhu -- ch.12. Statistics in biopharmaceutical research / Shein-Chung Chow and Annpey Pong -- ch.13. Statistics in toxicology / James J. Chen -- ch. 14. Some statistical issues of relevence to confirmatory trials / George Y. H. Chi ... [et al.] -- ch. 15. Statistics in genetics / Zhaohai Li and Minyu Xie -- ch. 16. Dose-response modeling in health risk assessment / Yiliang Zhu -- ch. 17. Statistical models and methods in infectious diseases / Hulin Wu and Shoujun Zhao -- ch. 18. Special models for sampling survey / Sujuan Gao -- ch. 19. The use of capture-recapture methodology in epidemiological surveillance / Anne Chao, H-C. Yang and P. S. F. Yip -- ch. 20. Statistical methods in the effect evaluation of mass screening for diseases / Qing Liu -- ch. 21. Causal inference / Zhi Geng -- ch. 22. Survival analysis / Danyu Lin -- ch. 23. Regression models for the analysis of longitudinal data / Colin Wu and Kai F. Yu -- ch. 24. Local modeling: density estimation and nonparametric regression / Jianqing Fan and Runze Li -- ch. 25. Bayesian methods / Minghui Chen and Keying Ye -- ch. 26. Stochastic process and their applications in medical science / Caixia Li and Ji-Qian Fang -- ch. 27. Tree-based methods / Heping Zhang -- ch. 28. Maximum likelihood estimation from incomplete data via EM-type algorithms / Chuanhai Liu -- ch. 29. Introduction to artificial neural networks / Jielai Xia, Jiang Hongwei and Tang Qiyi

Download or read book Statistical Thinking in Clinical Trials written by Michael A. Proschan and published by CRC Press. This book was released on 2021-11-24 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Thinking in Clinical Trials combines a relatively small number of key statistical principles and several instructive clinical trials to gently guide the reader through the statistical thinking needed in clinical trials. Randomization is the cornerstone of clinical trials and randomization-based inference is the cornerstone of this book. Read this book to learn the elegance and simplicity of re-randomization tests as the basis for statistical inference (the analyze as you randomize principle) and see how re-randomization tests can save a trial that required an unplanned, mid-course design change. Other principles enable the reader to quickly and confidently check calculations without relying on computer programs. The `EZ’ principle says that a single sample size formula can be applied to a multitude of statistical tests. The `O minus E except after V’ principle provides a simple estimator of the log odds ratio that is ideally suited for stratified analysis with a binary outcome. The same principle can be used to estimate the log hazard ratio and facilitate stratified analysis in a survival setting. Learn these and other simple techniques that will make you an invaluable clinical trial statistician.

Download or read book Statistical Methods for Global Health and Epidemiology written by Xinguang Chen and published by Springer Nature. This book was released on 2020-04-13 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines statistical methods and models used in the fields of global health and epidemiology. It includes methods such as innovative probability sampling, data harmonization and encryption, and advanced descriptive, analytical and monitory methods. Program codes using R are included as well as real data examples. Contemporary global health and epidemiology involves a myriad of medical and health challenges, including inequality of treatment, the HIV/AIDS epidemic and its subsequent control, the flu, cancer, tobacco control, drug use, and environmental pollution. In addition to its vast scales and telescopic perspective; addressing global health concerns often involves examining resource-limited populations with large geographic, socioeconomic diversities. Therefore, advancing global health requires new epidemiological design, new data, and new methods for sampling, data processing, and statistical analysis. This book provides global health researchers with methods that will enable access to and utilization of existing data. Featuring contributions from both epidemiological and biostatistical scholars, this book is a practical resource for researchers, practitioners, and students in solving global health problems in research, education, training, and consultation.

Download or read book Statistical Models in Epidemiology written by David Clayton and published by Oxford University Press, USA. This book was released on 2013-01-17 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This self-contained account of the statistical basis of epidemiology has been written for those with a basic training in biology. It is specifically intended for students enrolled for a masters degree in epidemiology, clinical epidemiology, or biostatistics.

Download or read book Biostatistics and Epidemiology written by Sylvia Wassertheil-Smoller and published by Springer Science & Business Media. This book was released on 2006-05-10 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the new edition of Biostatistics and Epidemiology, Dr. Wassertheil-Smoller has included several new chapters (genetic statistics, molecular epidemiology, scientific integrity and research ethics) and a new appendix on the basic concepts of genetics and a glossary of genetic terminology. She has also expanded the coverage of multi-center trials (an important aspect of implementation of the standards of evidence-based medicine), controversies in screening for prostate, colon, breast, and other cancers.

Download or read book Statistical Analysis of Epidemiologic Data written by Steve Selvin and published by Oxford University Press. This book was released on 2004-05-13 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analytic procedures suitable for the study of human disease are scattered throughout the statistical and epidemiologic literature. Explanations of their properties are frequently presented in mathematical and theoretical language. This well-established text gives readers a clear understanding of the statistical methods that are widely used in epidemiologic research without depending on advanced mathematical or statistical theory. By applying these methods to actual data, Selvin reveals the strengths and weaknesses of each analytic approach. He combines techniques from the fields of statistics, biostatistics, demography and epidemiology to present a comprehensive overview that does not require computational details of the statistical techniques described. For the Third Edition, Selvin took out some old material (e.g. the section on rarely used cross-over designs) and added new material (e.g. sections on frequently used contingency table analysis). Throughout the text he enriched existing discussions with new elements, including the analysis of multi-level categorical data and simple, intuitive arguments that exponential survival times cause the hazard function to be constant. He added a dozen new applied examples to illustrate such topics as the pitfalls of proportional mortality data, the analysis of matched pair categorical data, and the age-adjustment of mortality rates based on statistical models. The most important new feature is a chapter on Poisson regression analysis. This essential statistical tool permits the multivariable analysis of rates, probabilities and counts.

Download or read book Clinical Epidemiology and Biostatistics written by Michael S. Kramer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a book for clinicians, clinical investigators, trainees, and graduates who wish to develop their proficiency in the planning, execution, and interpretation of clinical and epidemiological research. Emphasis is placed on the design and analysis of research studies involving human subjects where the primary interest concerns principles of analytic (cause-and- effect) inference. The topic is presented from the standpoint of the clinician and assumes no previous knowledge of epidemiology, research design or statistics. Extensive use is made of illustrative examples from a variety of clinical specialties and subspecialties. The book is divided into three parts. Part I deals with epidemiological research design and analytic inference, including such issues as measurement, rates, analytic bias, and the main forms of observational and experimental epidemiological studies. Part II presents the principles and applications of biostatistics, with emphasis on statistical inference. Part III comprises four chapters covering such topics as diagnostic tests, decision analysis, survival (life-table) analysis, and causality.

Download or read book Epidemiology written by Mark Woodward and published by CRC Press. This book was released on 1999-05-25 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epidemiology is a subject of growing importance, as witnessed by its role in the description and prediction of the impact of new diseases such as AIDS and new-variant CJD. Epidemiology: Study Design and Data Analysis covers the whole spectrum of standard analytical techniques used in epidemiology, from descriptive techniques in report writing to model diagnostics from generalized linear models. The author discusses the advantages, disadvantages, and alternatives to case-control, cohort and intervention studies and details such crucial concepts as incidence, prevalence, confounding and interaction. Many exercises are provided, based on real epidemiological data sets collected from all over the world. The data sets are also available on an associated web site. Epidemiology: Study Design and Data Analysis will be an invaluable textbook for statistics and medical students studying epidemiology, and a standard reference for practicing epidemiologists.