Download or read book Survival Analysis written by John P. Klein and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Making complex methods more accessible to applied researchers without an advanced mathematical background, the authors present the essence of new techniques available, as well as classical techniques, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of practical notes at the end of each section, while technical details of the derivation of the techniques are sketched in the technical notes. This book will thus be useful for investigators who need to analyse censored or truncated life time data, and as a textbook for a graduate course in survival analysis, the only prerequisite being a standard course in statistical methodology.
Download or read book Statistical Methods for Survival Data Analysis written by Elisa T. Lee and published by Wiley-Interscience. This book was released on 1992-05-07 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functions of survival time; Examples of survival data analysis; Nonparametric methods of estimating survival functions; Nonparametric methods for comparing survival distributions; Some well-known survival distributions and their applications; Graphical methods for sulvival distribution fitting and goodness-of-fit tests; Analytical estimation procedures for sulvival distributions; Parametric methods for comparing two survival distribution; Identification of prognostic factors related to survival time; Identification of risk factors related to dichotomous data; Planning and design of clinical trials (I); Planning and design of clinicL trials(II).
Download or read book Handbook of Survival Analysis written by John P. Klein and published by CRC Press. This book was released on 2016-04-19 with total page 635 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Survival Analysis presents modern techniques and research problems in lifetime data analysis. This area of statistics deals with time-to-event data that is complicated by censoring and the dynamic nature of events occurring in time. With chapters written by leading researchers in the field, the handbook focuses on advances in survival analysis techniques, covering classical and Bayesian approaches. It gives a complete overview of the current status of survival analysis and should inspire further research in the field. Accessible to a wide range of readers, the book provides: An introduction to various areas in survival analysis for graduate students and novices A reference to modern investigations into survival analysis for more established researchers A text or supplement for a second or advanced course in survival analysis A useful guide to statistical methods for analyzing survival data experiments for practicing statisticians
Download or read book The Statistical Analysis of Interval censored Failure Time Data written by Jianguo Sun and published by Springer. This book was released on 2007-05-26 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book collects and unifies statistical models and methods that have been proposed for analyzing interval-censored failure time data. It provides the first comprehensive coverage of the topic of interval-censored data and complements the books on right-censored data. The focus of the book is on nonparametric and semiparametric inferences, but it also describes parametric and imputation approaches. This book provides an up-to-date reference for people who are conducting research on the analysis of interval-censored failure time data as well as for those who need to analyze interval-censored data to answer substantive questions.
Download or read book Survival Analysis Using S written by Mara Tableman and published by CRC Press. This book was released on 2003-07-28 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival Analysis Using S: Analysis of Time-to-Event Data is designed as a text for a one-semester or one-quarter course in survival analysis for upper-level or graduate students in statistics, biostatistics, and epidemiology. Prerequisites are a standard pre-calculus first course in probability and statistics, and a course in applied linear regression models. No prior knowledge of S or R is assumed. A wide choice of exercises is included, some intended for more advanced students with a first course in mathematical statistics. The authors emphasize parametric log-linear models, while also detailing nonparametric procedures along with model building and data diagnostics. Medical and public health researchers will find the discussion of cut point analysis with bootstrap validation, competing risks and the cumulative incidence estimator, and the analysis of left-truncated and right-censored data invaluable. The bootstrap procedure checks robustness of cut point analysis and determines cut point(s). In a chapter written by Stephen Portnoy, censored regression quantiles - a new nonparametric regression methodology (2003) - is developed to identify important forms of population heterogeneity and to detect departures from traditional Cox models. By generalizing the Kaplan-Meier estimator to regression models for conditional quantiles, this methods provides a valuable complement to traditional Cox proportional hazards approaches.
Download or read book Survival Analysis with Interval Censored Data written by Kris Bogaerts and published by CRC Press. This book was released on 2017-11-20 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival Analysis with Interval-Censored Data: A Practical Approach with Examples in R, SAS, and BUGS provides the reader with a practical introduction into the analysis of interval-censored survival times. Although many theoretical developments have appeared in the last fifty years, interval censoring is often ignored in practice. Many are unaware of the impact of inappropriately dealing with interval censoring. In addition, the necessary software is at times difficult to trace. This book fills in the gap between theory and practice. Features: -Provides an overview of frequentist as well as Bayesian methods. -Include a focus on practical aspects and applications. -Extensively illustrates the methods with examples using R, SAS, and BUGS. Full programs are available on a supplementary website. The authors: Kris Bogaerts is project manager at I-BioStat, KU Leuven. He received his PhD in science (statistics) at KU Leuven on the analysis of interval-censored data. He has gained expertise in a great variety of statistical topics with a focus on the design and analysis of clinical trials. Arnošt Komárek is associate professor of statistics at Charles University, Prague. His subject area of expertise covers mainly survival analysis with the emphasis on interval-censored data and classification based on longitudinal data. He is past chair of the Statistical Modelling Society and editor of Statistical Modelling: An International Journal. Emmanuel Lesaffre is professor of biostatistics at I-BioStat, KU Leuven. His research interests include Bayesian methods, longitudinal data analysis, statistical modelling, analysis of dental data, interval-censored data, misclassification issues, and clinical trials. He is the founding chair of the Statistical Modelling Society, past-president of the International Society for Clinical Biostatistics, and fellow of ISI and ASA.
Download or read book Lifetime Data Models in Reliability and Survival Analysis written by Nicholas P. Jewell and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical models and methods for lifetime and other time-to-event data are widely used in many fields, including medicine, the environmental sciences, actuarial science, engineering, economics, management, and the social sciences. For example, closely related statistical methods have been applied to the study of the incubation period of diseases such as AIDS, the remission time of cancers, life tables, the time-to-failure of engineering systems, employment duration, and the length of marriages. This volume contains a selection of papers based on the 1994 International Research Conference on Lifetime Data Models in Reliability and Survival Analysis, held at Harvard University. The conference brought together a varied group of researchers and practitioners to advance and promote statistical science in the many fields that deal with lifetime and other time-to-event-data. The volume illustrates the depth and diversity of the field. A few of the authors have published their conference presentations in the new journal Lifetime Data Analysis (Kluwer Academic Publishers).
Download or read book Statistical Analysis of Interval censored and Truncated Survival Data written by Hee-Jeong Lim and published by . This book was released on 2001 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data from clinical trials and epidemiological studies are often incomplete due to interval censoring and truncation. In this thesis, we will discuss the statistical analysis of survival data with interval-censoring and truncation. First, we consider the problem of comparing two failure time distributions based on interval-censored data. We propose three classes of nonparametric test procedures, which include most existing methods as special cases. To evaluate and compare the proposed and existing tests and to draw a guideline for selecting an appropriate test for a given situation, an extensive simulation study is conducted. Secondly, we consider the problem of estimating a survival function when there exists a change point. To obtain the maximum likelihood estimator of a survival function in this case, an EM algorithm is developed when the survival function is completely unknown before the change point and known up to a vector of unknown parameters after the change point. We evaluate the performance of the proposed algorithm and illustrate it using a set of survival data arising from an AIDS study. Thirdly, we consider a regression analysis of survival data with interval-censored covariates. To estimate regression parameters, methods based on estimating equations are developed. An extensive simulation study is performed to evaluate the proposed method.
Download or read book Analysis of Doubly Truncated Data written by Achim Dörre and published by Springer. This book was released on 2019-05-13 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces readers to statistical methodologies used to analyze doubly truncated data. The first book exclusively dedicated to the topic, it provides likelihood-based methods, Bayesian methods, non-parametric methods, and linear regression methods. These procedures can be used to effectively analyze continuous data, especially survival data arising in biostatistics and economics. Because truncation is a phenomenon that is often encountered in non-experimental studies, the methods presented here can be applied to many branches of science. The book provides R codes for most of the statistical methods, to help readers analyze their data. Given its scope, the book is ideally suited as a textbook for students of statistics, mathematics, econometrics, and other fields.
Download or read book Survival Analysis written by Rupert G. Miller, Jr. and published by John Wiley & Sons. This book was released on 2011-01-25 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise summary of the statistical methods used in the analysis of survival data with censoring. Emphasizes recently developed nonparametric techniques. Outlines methods in detail and illustrates them with actual data. Discusses the theory behind each method. Includes numerous worked problems and numerical exercises.
Download or read book Statistical Methods for Truncated Survival Data written by Lior Rennert and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Truncation is a well-known phenomenon that may be present in observational studies of time-to-event data. For example, autopsy-confirmed survival studies of neurodegenerative diseases are subject to selection bias due to the simultaneous presence of left and right truncation, also known as double truncation. While many methods exist to adjust for either left or right truncation, there are very few methods that adjust for double truncation. When time-to-event data is doubly truncated, the regression coefficient estimators from the standard Cox regression model will be biased. In this dissertation, we develop two novel methods to adjust for double truncation when fitting the Cox regression model. The first method uses a weighted estimating equation approach. This method assumes the survival and truncation times are independent. The second method relaxes this independence assumption to an assumption of conditional independence between the survival and truncation times. As opposed to methods that ignore truncation, we show that both proposed methods result in consistent and asymptotically normal regression coefficient estimators and have little bias in small samples. We use these proposed methods to assess the effect of cognitive reserve on survival in individuals with autopsy-confirmed Alzheimer's disease. We also conduct an extensive simulation study to compare survival distribution function estimators in the presence of double truncation and conduct a case study to compare the survival times of individuals with autopsy-confirmed Alzheimer's disease and frontotemporal lobar degeneration. Furthermore, we introduce an R-package for the above methods to adjust for double truncation when fitting the Cox model and estimating the survival distribution function.
Download or read book The Statistical Analysis of Doubly Truncated Data written by Jacobo de Uña-Álvarez and published by John Wiley & Sons. This book was released on 2021-11-10 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough treatment of the statistical methods used to analyze doubly truncated data In The Statistical Analysis of Doubly Truncated Data, an expert team of statisticians delivers an up-to-date review of existing methods used to deal with randomly truncated data, with a focus on the challenging problem of random double truncation. The authors comprehensively introduce doubly truncated data before moving on to discussions of the latest developments in the field. The book offers readers examples with R code along with real data from astronomy, engineering, and the biomedical sciences to illustrate and highlight the methods described within. Linear regression models for doubly truncated responses are provided and the influence of the bandwidth in the performance of kernel-type estimators, as well as guidelines for the selection of the smoothing parameter, are explored. Fully nonparametric and semiparametric estimators are explored and illustrated with real data. R code for reproducing the data examples is also provided. The book also offers: A thorough introduction to the existing methods that deal with randomly truncated data Comprehensive explorations of linear regression models for doubly truncated responses Practical discussions of the influence of bandwidth in the performance of kernel-type estimators and guidelines for the selection of the smoothing parameter In-depth examinations of nonparametric and semiparametric estimators Perfect for statistical professionals with some background in mathematical statistics, biostatisticians, and mathematicians with an interest in survival analysis and epidemiology, The Statistical Analysis of Doubly Truncated Data is also an invaluable addition to the libraries of biomedical scientists and practitioners, as well as postgraduate students studying survival analysis.
Download or read book Lifetime Data Statistical Models And Methods Second Edition written by Jayant V Deshpande and published by World Scientific Publishing Company. This book was released on 2015-12-15 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is meant for postgraduate modules that cover lifetime data in reliability and survival analysis as taught in statistics, engineering statistics and medical statistics courses. It is helpful for researchers who wish to choose appropriate models and methods for analyzing lifetime data. There is an extensive discussion on the concept and role of ageing in choosing appropriate models for lifetime data, with a special emphasis on tests of exponentiality. There are interesting contributions related to the topics of ageing, tests for exponentiality, competing risks and repairable systems. A special feature of this book is that it introduces the public domain R-software and explains how it can be used in computations of methods discussed in the book.This new edition includes new sections on Frailty Models and Accelerated Life Time Models. Many more illustrations and exercises are also included.
Download or read book Survival Analysis written by H J Vaman and published by CRC Press. This book was released on 2022-08-26 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival analysis generally deals with analysis of data arising from clinical trials. Censoring, truncation, and missing data create analytical challenges and the statistical methods and inference require novel and different approaches for analysis. Statistical properties, essentially asymptotic ones, of the estimators and tests are aptly handled in the counting process framework which is drawn from the larger arm of stochastic calculus. With explosion of data generation during the past two decades, survival data has also enlarged assuming a gigantic size. Most statistical methods developed before the millennium were based on a linear approach even in the face of complex nature of survival data. Nonparametric nonlinear methods are best envisaged in the Machine Learning school. This book attempts to cover all these aspects in a concise way. Survival Analysis offers an integrated blend of statistical methods and machine learning useful in analysis of survival data. The purpose of the offering is to give an exposure to the machine learning trends for lifetime data analysis. Features: Classical survival analysis techniques for estimating statistical functional and hypotheses testing Regression methods covering the popular Cox relative risk regression model, Aalen’s additive hazards model, etc. Information criteria to facilitate model selection including Akaike, Bayes, and Focused Penalized methods Survival trees and ensemble techniques of bagging, boosting, and random survival forests A brief exposure of neural networks for survival data R program illustration throughout the book
Download or read book Survival Models and Data Analysis written by Regina C. Elandt-Johnson and published by John Wiley & Sons. This book was released on 2014-11-05 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival analysis deals with the distribution of life times, essentially the times from an initiating event such as birth or the start of a job to some terminal event such as death or pension. This book, originally published in 1980, surveys and analyzes methods that use survival measurements and concepts, and helps readers apply the appropriate method for a given situation. Four broad sections cover introductions to data, univariate survival function, multiple-failure data, and advanced topics.
Download or read book Analysis of Survival Data written by D.R. Cox and published by CRC Press. This book was released on 1984-06-01 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph contains many ideas on the analysis of survival data to present a comprehensive account of the field. The value of survival analysis is not confined to medical statistics, where the benefit of the analysis of data on such factors as life expectancy and duration of periods of freedom from symptoms of a disease as related to a treatment applied individual histories and so on, is obvious. The techniques also find important applications in industrial life testing and a range of subjects from physics to econometrics. In the eleven chapters of the book the methods and applications of are discussed and illustrated by examples.
Download or read book Analysis of Survival Data with Dependent Censoring written by Takeshi Emura and published by Springer. This book was released on 2018-04-05 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces readers to copula-based statistical methods for analyzing survival data involving dependent censoring. Primarily focusing on likelihood-based methods performed under copula models, it is the first book solely devoted to the problem of dependent censoring. The book demonstrates the advantages of the copula-based methods in the context of medical research, especially with regard to cancer patients’ survival data. Needless to say, the statistical methods presented here can also be applied to many other branches of science, especially in reliability, where survival analysis plays an important role. The book can be used as a textbook for graduate coursework or a short course aimed at (bio-) statisticians. To deepen readers’ understanding of copula-based approaches, the book provides an accessible introduction to basic survival analysis and explains the mathematical foundations of copula-based survival models.
