Download or read book Medical Product Safety Evaluation written by Jie Chen and published by CRC Press. This book was released on 2018-09-03 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in the design and analysis of safety studies are discussed with illustrative applications and examples. Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in the design and analysis of safety studies are discussed with illustrative applications and examples. The book is designed not only for biopharmaceutical professionals, such as statisticians, safety specialists, pharmacovigilance experts, and pharmacoepidemiologists, who can use the book as self-learning materials or in short courses or training programs, but also for graduate students in statistics and biomedical data science for a one-semester course. Each chapter provides supplements and problems as more readings and exercises.
Download or read book Statistical Methods and Modeling and Safety Data Analysis and Evaluation written by National Research Council (U.S.). Transportation Research Board and published by . This book was released on 2003 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers empirical approaches to outlier detection in intelligent transportation systems data, modeling of traffic crash-flow relationships for intersections, profiling of high-frequency accident locations by use of association rules, analysis of rollovers and injuries with sport utility vehicles, and automated accident detection at intersections via digital audio signal processing.
Download or read book Statistical Methods for Categorical Data Analysis written by Daniel Powers and published by Emerald Group Publishing. This book was released on 2008-11-13 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive introduction to methods and models for categorical data analysis and their applications in social science research. Companion website also available, at https://webspace.utexas.edu/dpowers/www/
Download or read book Statistical Modeling and Analysis for Database Marketing written by Bruce Ratner and published by CRC Press. This book was released on 2003-05-28 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional statistical methods are limited in their ability to meet the modern challenge of mining large amounts of data. Data miners, analysts, and statisticians are searching for innovative new data mining techniques with greater predictive power, an attribute critical for reliable models and analyses. Statistical Modeling and Analysis fo
Download or read book Statistical Methods for Evaluating Safety in Medical Product Development written by A. Lawrence Gould and published by John Wiley & Sons. This book was released on 2015-02-23 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each chapter provides sufficient detail to the reader to undertake the design and analysis of experiments at various stages of product development, including comprehensive references to the relevant literature. Provides a guide to statistical methods and application in medical product development Assists readers in undertaking design and analysis of experiments at various stages of product development Features case studies throughout the book, as well as, SAS and R code
Download or read book Statistical Methods Safety Data Analysis and Evaluation 2007 written by and published by . This book was released on 2007 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Statistical Methods and Safety Data Analysis and Evaluation written by National Research Council (U.S.). Transportation Research Board and published by . This book was released on 2004 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Predictive Safety Analytics written by Robert Stevens and published by CRC Press. This book was released on 2023-10-03 with total page 99 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly all our safety data collection and reporting systems are backwardlooking: incident reports; dashboards; compliance monitoring systems; and so on. This book shows how we can use safety data in a forward-looking, predictive sense. Predictive Safety Analytics: Reducing Risk through Modeling and Machine Learning contains real use cases where organizations have reduced incidents by employing predictive analytics to foresee and mitigate future risks. It discusses how Predictive Safety Analytics is an opportunity to break through the plateau problem where safety rate improvements have stagnated in many organizations. The book presents how the use of data, coupled with advanced analytical techniques, including machine learning, has become a proven and successful innovation. Emphasis is placed on how the book can “meet you where you are” by illuminating a path to get there, starting with simple data the organization likely already has. Highlights of the book are the real examples and case studies that will assist in generating thoughts and ideas for what might work for individual readers and how they can adapt the information to their particular situations. This book is written for professionals and researchers in system reliability, risk and safety assessment, quality control, operational managers in selected industries, data scientists, and ML engineers. Students taking courses in these areas will also find this book of interest to them.
Download or read book Commercial Motor Vehicle Driver Fatigue Long Term Health and Highway Safety written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-09-12 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are approximately 4,000 fatalities in crashes involving trucks and buses in the United States each year. Though estimates are wide-ranging, possibly 10 to 20 percent of these crashes might have involved fatigued drivers. The stresses associated with their particular jobs (irregular schedules, etc.) and the lifestyle that many truck and bus drivers lead, puts them at substantial risk for insufficient sleep and for developing short- and long-term health problems. Commercial Motor Vehicle Driver Fatigue, Long-Term Health and Highway Safety assesses the state of knowledge about the relationship of such factors as hours of driving, hours on duty, and periods of rest to the fatigue experienced by truck and bus drivers while driving and the implications for the safe operation of their vehicles. This report evaluates the relationship of these factors to drivers' health over the longer term, and identifies improvements in data and research methods that can lead to better understanding in both areas.
Download or read book Statistical and Machine Learning Data Mining written by Bruce Ratner and published by CRC Press. This book was released on 2012-02-28 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of a bestseller, Statistical and Machine-Learning Data Mining: Techniques for Better Predictive Modeling and Analysis of Big Data is still the only book, to date, to distinguish between statistical data mining and machine-learning data mining. The first edition, titled Statistical Modeling and Analysis for Database Marketing: Effective Techniques for Mining Big Data, contained 17 chapters of innovative and practical statistical data mining techniques. In this second edition, renamed to reflect the increased coverage of machine-learning data mining techniques, the author has completely revised, reorganized, and repositioned the original chapters and produced 14 new chapters of creative and useful machine-learning data mining techniques. In sum, the 31 chapters of simple yet insightful quantitative techniques make this book unique in the field of data mining literature. The statistical data mining methods effectively consider big data for identifying structures (variables) with the appropriate predictive power in order to yield reliable and robust large-scale statistical models and analyses. In contrast, the author's own GenIQ Model provides machine-learning solutions to common and virtually unapproachable statistical problems. GenIQ makes this possible — its utilitarian data mining features start where statistical data mining stops. This book contains essays offering detailed background, discussion, and illustration of specific methods for solving the most commonly experienced problems in predictive modeling and analysis of big data. They address each methodology and assign its application to a specific type of problem. To better ground readers, the book provides an in-depth discussion of the basic methodologies of predictive modeling and analysis. While this type of overview has been attempted before, this approach offers a truly nitty-gritty, step-by-step method that both tyros and experts in the field can enjoy playing with.
Download or read book Advances in Statistical Methods for the Health Sciences written by Jean-Louis Auget and published by Springer Science & Business Media. This book was released on 2007-08-08 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical methods have become an increasingly important and integral part of research in the health sciences. Many sophisticated methodologies have been developed for specific applications and problems. This self-contained comprehensive volume covers a wide range of topics pertaining to new statistical methods in the health sciences, including epidemiology, pharmacovigilance, quality of life, survival analysis, and genomics. The book will serve the health science community as well as practitioners, researchers, and graduate students in applied probability, statistics, and biostatistics.
Download or read book Chemical Process Performance Evaluation written by Ali Cinar and published by CRC Press. This book was released on 2007-01-11 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest advances in process monitoring, data analysis, and control systems are increasingly useful for maintaining the safety, flexibility, and environmental compliance of industrial manufacturing operations. Focusing on continuous, multivariate processes, Chemical Process Performance Evaluation introduces statistical methods and modeling te
Download or read book Quantitative Drug Safety and Benefit Risk Evaluation written by William Wang and published by CRC Press. This book was released on 2021-12-30 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative Methodologies and Process for Safety Monitoring and Ongoing Benefit Risk Evaluation provides a comprehensive coverage on safety monitoring methodologies, covering both global trends and regional initiatives. Pharmacovigilance has traditionally focused on the handling of individual adverse event reports however recently there had been a shift towards aggregate analysis to better understand the scope of product risks. Written to be accessible not only to statisticians but also to safety scientists with a quantitative interest, this book aims to bridge the gap in knowledge between medical and statistical fields creating a truly multi-disciplinary approach that is very much needed for 21st century safety evaluation.
Download or read book Statistical Methods and the Improvement of Data Quality written by Tommy Wright and published by Academic Press. This book was released on 2014-05-10 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Methods and the Improvement of Data Quality contains the proceedings of The Small Conference on the Improvement of the Quality of Data Collected by Data Collection Systems, held on November 11-12, 1982, in Oak Ridge, Tennessee. The conference provided a forum for discussing the use of statistical methods to improve data quality, with emphasis on the problems of data collection systems and how to handle them using state-of-the-art techniques. Comprised of 16 chapters, this volume begins with an overview of some of the limitations of surveys, followed by an annotated bibliography on frames from which the probability sample is selected. The reader is then introduced to sample designs and methods for collecting data over space and time; response effects to behavior and attitude questions; and how to develop and use error profiles. Subsequent chapters focus on principles and methods for handling outliers in data sets; influence functions, outlier detection, and data editing; and application of pattern recognition techniques to data analysis. The use of exploratory data analysis as an aid in modeling and statistical forecasting is also described. This monograph is likely to be of primary benefit to students taking a general course in survey sampling techniques, and to individuals and groups who deal with large data collection systems and are constantly seeking ways to improve the overall quality of their data.
Download or read book Statistical Methods written by National Research Council (U.S.). Transportation Research Board and published by . This book was released on 2005 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Transportation Research Record contains 28 papers dealing with statistical methods in highway safety research; highway safety data, analysis, and evaluation; occupant protection; and systematic reviews and meta-analysis. The papers address such topics as risk and crash prediction models, crashes on freeways and at signalized intersections, multivehicle crash prediction, speed and safety, red light running crashes, freeway lane closures, ramp design, accident exposure, rumble strip benefits, collisions with median trees, intersection safety, accident reconstruction, safety effects of speed limit changes, geometric design and head-on crashes, deer-vehicle crashes, sport utility vehicle rollover, vehicle occupancy and crash risk, a logit model for studying injury severity, abdominal injuries in rail passengers, healthy transport policies, and meta-analysis.
Download or read book The Statistical Analysis of Recurrent Events written by Richard J. Cook and published by Springer Science & Business Media. This book was released on 2007-08-02 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents models and statistical methods for the analysis of recurrent event data. The authors provide broad, detailed coverage of the major approaches to analysis, while emphasizing the modeling assumptions that they are based on. More general intensity-based models are also considered, as well as simpler models that focus on rate or mean functions. Parametric, nonparametric and semiparametric methodologies are all covered, with procedures for estimation, testing and model checking.
Download or read book Mathematical and Statistical Skills in the Biopharmaceutical Industry written by Arkadiy Pitman and published by CRC Press. This book was released on 2019-07-15 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach describes a philosophy of efficient problem solving showcased using examples pertinent to the biostatistics function in clinical drug development. It was written to share a quintessence of the authors’ experiences acquired during many years of relevant work in the biopharmaceutical industry. The book will be useful will be useful for biopharmaceutical industry statisticians at different seniority levels and for graduate students who consider a biostatistics-related career in this industry. Features: Describes a system of principles for pragmatic problem solving in clinical drug development. Discusses differences in the work of a biostatistician in small pharma and big pharma. Explains the importance/relevance of statistical programming and data management for biostatistics and necessity for integration on various levels. Describes some useful statistical background that can be capitalized upon in the drug development enterprise. Explains some hot topics and current trends in biostatistics in simple, non-technical terms. Discusses incompleteness of any system of standard operating procedures, rules and regulations. Provides a classification of scoring systems and proposes a novel approach for evaluation of the safety outcome for a completed randomized clinical trial. Presents applications of the problem solving philosophy in a highly problematic transfusion field where many investigational compounds have failed. Discusses realistic planning of open-ended projects.
