Download or read book Statistical Concepts and Applications in Clinical Medicine written by John Aitchison and published by CRC Press. This book was released on 2004-10-28 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Concepts and Applications in Clinical Medicine presents a unique, problem-oriented approach to using statistical methods in clinical medical practice through each stage of the clinical process, including observation, diagnosis, and treatment. The authors present each consultative problem in its original form, then describe the process of problem formulation, develop the appropriate statistical models, and interpret the statistical analysis in the context of the real problem. Their treatment provides clear, accessible explanations of statistical methods. The text includes end-of-chapter exercises that help develop formulatory, analytic, and interpretative skills.
Download or read book Statistical Concepts and Applications in Clinical Medicine written by John Aitchison and published by CRC Press. This book was released on 2004-10-28 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Concepts and Applications in Clinical Medicine presents a unique, problem-oriented approach to using statistical methods in clinical medical practice through each stage of the clinical process, including observation, diagnosis, and treatment. The authors present each consultative problem in its original form, then describe the process o
Download or read book Practical Statistics for Medical Research written by Douglas G. Altman and published by CRC Press. This book was released on 1990-11-22 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Practical Statistics for Medical Research is a problem-based text for medical researchers, medical students, and others in the medical arena who need to use statistics but have no specialized mathematics background. The author draws on twenty years of experience as a consulting medical statistician to provide clear explanations to key statistical concepts, with a firm emphasis on practical aspects of designing and analyzing medical research. Using real data and including dozens of interesting data sets, this bestselling text gives special attention to the presentation and interpretation of results and the many real problems that arise in medical research.
Download or read book Investigating Statistical Concepts Applications and Methods written by Beth L. Chance and published by Duxbury Press. This book was released on 2006 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: INVESTIGATING STATISTICAL CONCEPTS, APPLICATIONS, AND METHODS (WITH CD-ROM) combines investigation and exposition to explore statistical ideas and techniques. Many of the investigations ask you to use technology such as statistical software and Java applets. A combination of practice, homework, and application problems emphasize actual studies.
Download or read book Clinical Prediction Models written by Ewout W. Steyerberg and published by Springer. This book was released on 2019-07-22 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this volume provides insight and practical illustrations on how modern statistical concepts and regression methods can be applied in medical prediction problems, including diagnostic and prognostic outcomes. Many advances have been made in statistical approaches towards outcome prediction, but a sensible strategy is needed for model development, validation, and updating, such that prediction models can better support medical practice. There is an increasing need for personalized evidence-based medicine that uses an individualized approach to medical decision-making. In this Big Data era, there is expanded access to large volumes of routinely collected data and an increased number of applications for prediction models, such as targeted early detection of disease and individualized approaches to diagnostic testing and treatment. Clinical Prediction Models presents a practical checklist that needs to be considered for development of a valid prediction model. Steps include preliminary considerations such as dealing with missing values; coding of predictors; selection of main effects and interactions for a multivariable model; estimation of model parameters with shrinkage methods and incorporation of external data; evaluation of performance and usefulness; internal validation; and presentation formatting. The text also addresses common issues that make prediction models suboptimal, such as small sample sizes, exaggerated claims, and poor generalizability. The text is primarily intended for clinical epidemiologists and biostatisticians. Including many case studies and publicly available R code and data sets, the book is also appropriate as a textbook for a graduate course on predictive modeling in diagnosis and prognosis. While practical in nature, the book also provides a philosophical perspective on data analysis in medicine that goes beyond predictive modeling. Updates to this new and expanded edition include: • A discussion of Big Data and its implications for the design of prediction models • Machine learning issues • More simulations with missing ‘y’ values • Extended discussion on between-cohort heterogeneity • Description of ShinyApp • Updated LASSO illustration • New case studies
Download or read book Statistics in Medicine written by Robert H. Riffenburgh and published by Academic Press. This book was released on 2006 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine deals with treatments that work often but not always, so treatment success must be based on probability. Statistical methods lift medical research from the anecdotal to measured levels of probability. This book presents the common statistical methods used in 90% of medical research, along with the underlying basics, in two parts: a textbook section for use by students in health care training programs, e.g., medical schools or residency training, and a reference section for use by practicing clinicians in reading medical literature and performing their own research. The book does not require a significant level of mathematical knowledge and couches the methods in multiple examples drawn from clinical medicine, giving it applicable context. Easy-to-follow format incorporates medical examples, step-by-step methods, and check yourself exercises Two-part design features course material and a professional reference section Chapter summaries provide a review of formulas, method algorithms, and check lists Companion site links to statistical databases that can be downloaded and used to perform the exercises from the book and practice statistical methods New in this Edition: New chapters on: multifactor tests on means of continuous data, equivalence testing, and advanced methods New topics include: trial randomization, treatment ethics in medical research, imputation of missing data, and making evidence-based medical decisions Updated database coverage and additional exercises Expanded coverage of numbers needed to treat and to benefit, and regression analysis including stepwise regression and Cox regression Thorough discussion on required sample size
Download or read book How to Report Statistics in Medicine written by Thomas Allen Lang and published by ACP Press. This book was released on 2006 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents a comprehensive and comprehensible set of guidelines for reporting the statistical analyses and research designs and activities commonly used in biomedical research.
Download or read book Statistical Shape and Deformation Analysis written by Guoyan Zheng and published by Academic Press. This book was released on 2017-03-23 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Shape and Deformation Analysis: Methods, Implementation and Applications contributes enormously to solving different problems in patient care and physical anthropology, ranging from improved automatic registration and segmentation in medical image computing to the study of genetics, evolution and comparative form in physical anthropology and biology. This book gives a clear description of the concepts, methods, algorithms and techniques developed over the last three decades that is followed by examples of their implementation using open source software. Applications of statistical shape and deformation analysis are given for a wide variety of fields, including biometry, anthropology, medical image analysis and clinical practice. - Presents an accessible introduction to the basic concepts, methods, algorithms and techniques in statistical shape and deformation analysis - Includes implementation examples using open source software - Covers real-life applications of statistical shape and deformation analysis methods
Download or read book Methods and Applications of Statistics in Clinical Trials Volume 2 written by Narayanaswamy Balakrishnan and published by John Wiley & Sons. This book was released on 2014-06-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods and Applications of Statistics in Clinical Trials, Volume 2: Planning, Analysis, and Inferential Methods includes updates of established literature from the Wiley Encyclopedia of Clinical Trials as well as original material based on the latest developments in clinical trials. Prepared by a leading expert, the second volume includes numerous contributions from current prominent experts in the field of medical research. In addition, the volume features: • Multiple new articles exploring emerging topics, such as evaluation methods with threshold, empirical likelihood methods, nonparametric ROC analysis, over- and under-dispersed models, and multi-armed bandit problems • Up-to-date research on the Cox proportional hazard model, frailty models, trial reports, intrarater reliability, conditional power, and the kappa index • Key qualitative issues including cost-effectiveness analysis, publication bias, and regulatory issues, which are crucial to the planning and data management of clinical trials
Download or read book Medical Statistics at a Glance written by Aviva Petrie and published by John Wiley & Sons. This book was released on 2019-09-30 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fourth edition, Medical Statistics at a Glance is a concise and accessible introduction to this complex subject. It provides clear instruction on how to apply commonly used statistical procedures in an easy-to-read, comprehensive and relevant volume. This new edition continues to be the ideal introductory manual and reference guide to medical statistics, an invaluable companion for statistics lectures and a very useful revision aid. This new edition of Medical Statistics at a Glance: Offers guidance on the practical application of statistical methods in conducting research and presenting results Explains the underlying concepts of medical statistics and presents the key facts without being unduly mathematical Contains succinct self-contained chapters, each with one or more examples, many of them new, to illustrate the use of the methodology described in the chapter. Now provides templates for critical appraisal, checklists for the reporting of randomized controlled trials and observational studies and references to the EQUATOR guidelines for the presentation of study results for many other types of study Includes extensive cross-referencing, flowcharts to aid the choice of appropriate tests, learning objectives for each chapter, a glossary of terms and a glossary of annotated full computer output relevant to the examples in the text Provides cross-referencing to the multiple choice and structured questions in the companion Medical Statistics at a Glance Workbook Medical Statistics at a Glance is a must-have text for undergraduate and post-graduate medical students, medical researchers and biomedical and pharmaceutical professionals.
Download or read book Methods and Applications of Statistics in Clinical Trials Volume 1 written by Narayanaswamy Balakrishnan and published by John Wiley & Sons. This book was released on 2014-03-05 with total page 937 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to the key statistical concepts essential for the design and construction of clinical trials As the newest major resource in the field of medical research, Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs presents a timely and authoritative reviewof the central statistical concepts used to build clinical trials that obtain the best results. The referenceunveils modern approaches vital to understanding, creating, and evaluating data obtained throughoutthe various stages of clinical trial design and analysis. Accessible and comprehensive, the first volume in a two-part set includes newly-written articles as well as established literature from the Wiley Encyclopedia of Clinical Trials. Illustrating a variety of statistical concepts and principles such as longitudinal data, missing data, covariates, biased-coin randomization, repeated measurements, and simple randomization, the book also provides in-depth coverage of the various trial designs found within phase I-IV trials. Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs also features: Detailed chapters on the type of trial designs, such as adaptive, crossover, group-randomized, multicenter, non-inferiority, non-randomized, open-labeled, preference, prevention, and superiority trials Over 100 contributions from leading academics, researchers, and practitioners An exploration of ongoing, cutting-edge clinical trials on early cancer and heart disease, mother-to-child human immunodeficiency virus transmission trials, and the AIDS Clinical Trials Group Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs is an excellent reference for researchers, practitioners, and students in the fields of clinicaltrials, pharmaceutics, biostatistics, medical research design, biology, biomedicine, epidemiology,and public health.
Download or read book Medical Statistics written by Ramakrishna HK and published by Springer. This book was released on 2016-11-08 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with statistics in medicine in a simple way. The text is supported by abundant examples from medical data. This book aims to explain and simplify the process of data presentation. Further aspects addressed include how to design and conduct clinical trials, and how to write journal articles.
Download or read book A Statistical Approach to Genetic Epidemiology written by Andreas Ziegler and published by John Wiley & Sons. This book was released on 2011-08-24 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Statistical Approach to Genetic Epidemiology After studying statistics and mathematics at the University of Munich and obtaining his doctoral degree from the University of Dortmund, Andreas Ziegler received the Johann-Peter-Süssmilch-Medal of the German Association for Medical Informatics, Biometry and Epidemiology for his post-doctoral work on “Model Free Linkage Analysis of Quantitative Traits” in 1999. In 2004, he was one of the recipients of the Fritz-Linder-Forum-Award from the German Association for Surgery.
Download or read book Time Series Modeling of Neuroscience Data written by Tohru Ozaki and published by CRC Press. This book was released on 2012-01-26 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in brain science measurement technology have given researchers access to very large-scale time series data such as EEG/MEG data (20 to 100 dimensional) and fMRI (140,000 dimensional) data. To analyze such massive data, efficient computational and statistical methods are required.Time Series Modeling of Neuroscience Data shows how to
Download or read book Flexible Imputation of Missing Data written by Stef van Buuren and published by CRC Press. This book was released on 2012-03-29 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Missing data form a problem in every scientific discipline, yet the techniques required to handle them are complicated and often lacking. One of the great ideas in statistical science—multiple imputation—fills gaps in the data with plausible values, the uncertainty of which is coded in the data itself. It also solves other problems, many of which are missing data problems in disguise. Flexible Imputation of Missing Data is supported by many examples using real data taken from the author's vast experience of collaborative research, and presents a practical guide for handling missing data under the framework of multiple imputation. Furthermore, detailed guidance of implementation in R using the author’s package MICE is included throughout the book. Assuming familiarity with basic statistical concepts and multivariate methods, Flexible Imputation of Missing Data is intended for two audiences: (Bio)statisticians, epidemiologists, and methodologists in the social and health sciences Substantive researchers who do not call themselves statisticians, but who possess the necessary skills to understand the principles and to follow the recipes This graduate-tested book avoids mathematical and technical details as much as possible: formulas are accompanied by a verbal statement that explains the formula in layperson terms. Readers less concerned with the theoretical underpinnings will be able to pick up the general idea, and technical material is available for those who desire deeper understanding. The analyses can be replicated in R using a dedicated package developed by the author.
Download or read book Analysis of Capture Recapture Data written by Rachel S. McCrea and published by CRC Press. This book was released on 2014-08-01 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important first step in studying the demography of wild animals is to identify the animals uniquely through applying markings, such as rings, tags, and bands. Once the animals are encountered again, researchers can study different forms of capture-recapture data to estimate features, such as the mortality and size of the populations. Capture-rec
Download or read book Correspondence Analysis in Practice written by Michael Greenacre and published by CRC Press. This book was released on 2007-05-07 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on the author’s experience in social and environmental research, Correspondence Analysis in Practice, Second Edition shows how the versatile method of correspondence analysis (CA) can be used for data visualization in a wide variety of situations. This completely revised, up-to-date edition features a didactic approach with self-contained chapters, extensive marginal notes, informative figure and table captions, and end-of-chapter summaries. New to the Second Edition • Five new chapters on transition and regression relationships, stacked tables, subset correspondence analysis, analysis of square tables, and canonical correspondence analysis • Substantially more figures and tables than the first edition • A computational appendix that provides the R commands that correspond to most of the analyses featured throughout the book, making it easy for readers to reproduce the analyses With 33 years of CA experience, the expert author demonstrates how to use uncomplicated, relatively nonmathematical techniques to translate complex tabular data into more readable graphical forms. CA and its variants multiple CA (MCA) and joint CA (JCA) are suitable for analyses in various fields, including marketing research, the social and environmental sciences, biochemistry, and more.
