Download or read book Engineering Simulations as Scientific Instruments A Pattern Language written by Susan Stepney and published by Springer. This book was released on 2018-11-01 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes CoSMoS (Complex Systems Modelling and Simulation), a pattern-based approach to engineering trustworthy simulations that are both scientifically useful to the researcher and scientifically credible to third parties. This approach emphasises three key aspects to this development of a simulation as a scientific instrument: the use of explicit models to capture the scientific domain, the engineered simulation platform, and the experimental results of running simulations; the use of arguments to provide evidence that the scientific instrument is fit for purpose; and the close co-working of domain scientists and simulation software engineers. In Part I the authors provide a managerial overview: the rationale for and benefits of using the CoSMoS approach, and a small worked example to demonstrate it in action. Part II is a catalogue of the core patterns. Part III lists more specific “helper” patterns, showing possible routes to a simulation. Finally Part IV documents CellBranch, a substantial case study developed using the CoSMoS approach.
Download or read book From Astrophysics to Unconventional Computation written by Andrew Adamatzky and published by Springer. This book was released on 2019-04-16 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Festschrift is a tribute to Susan Stepney’s ideas and achievements in the areas of computer science, formal specifications and proofs, complex systems, unconventional computing, artificial chemistry, and artificial life. All chapters were written by internationally recognised leaders in computer science, physics, mathematics, and engineering. The book shares fascinating ideas, algorithms and implementations related to the formal specification of programming languages and applications, behavioural inheritance, modelling and analysis of complex systems, parallel computing and non-universality, growing cities, artificial life, evolving artificial neural networks, and unconventional computing. Accordingly, it offers an insightful and enjoyable work for readers from all walks of life, from undergraduate students to university professors, from mathematicians, computers scientists and engineers to physicists, chemists and biologists.
Download or read book Reverse Vaccinology written by Pedro A Reche and published by Frontiers Media SA. This book was released on 2020-01-15 with total page 139 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computational Immunology written by Josep Bassaganya-Riera and published by Academic Press. This book was released on 2015-10-21 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling. - Offers case studies with different levels of complexity - Provides a detailed view on cutting-edge tools for modeling that are useful to experimentalists with limited computational skills - Explores the usage of simulation for hypothesis generation, helping the reader to understand the most valuable points on experimental setting
Download or read book Immunological Aspects of Emerging and Re emerging Zoonoses written by Wei Wang and published by Frontiers Media SA. This book was released on 2024-03-20 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zoonosis is an infectious disease that has jumped from non-human animals to humans. To date, more than 200 known types of zoonoses have been identified, and 60% of emerging infectious diseases are zoonotic. It is estimated that zoonoses are responsible for 2.5 billion cases of human illness and 2.7 million human deaths worldwide each year, and 50-60% of the global population (5–6 billion) are projected to be at risk of zoonotic infections. Emerging and re-emerging zoonoses, such as monkeypox, Ebola, SARS, MERS, Zika, Rickettsia, and Mycobacteria, pose an immense and growing threat to global health, economy, and safety. As of September 26, 2022, there have been more than 600 million cases confirmed with COVID-19, and 6,514,397 deaths occurred due to this highly communicable disease. Identification of the immunological aspects of emerging and re-emerging zoonoses may facilitate the diagnosis, vaccine, and therapeutics development of emerging and re-emerging zoonoses.
Download or read book Individual based Modeling and Ecology written by Volker Grimm and published by Princeton University Press. This book was released on 2013-11-28 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Individual-based models are an exciting and widely used new tool for ecology. These computational models allow scientists to explore the mechanisms through which population and ecosystem ecology arises from how individuals interact with each other and their environment. This book provides the first in-depth treatment of individual-based modeling and its use to develop theoretical understanding of how ecological systems work, an approach the authors call "individual-based ecology.? Grimm and Railsback start with a general primer on modeling: how to design models that are as simple as possible while still allowing specific problems to be solved, and how to move efficiently through a cycle of pattern-oriented model design, implementation, and analysis. Next, they address the problems of theory and conceptual framework for individual-based ecology: What is "theory"? That is, how do we develop reusable models of how system dynamics arise from characteristics of individuals? What conceptual framework do we use when the classical differential equation framework no longer applies? An extensive review illustrates the ecological problems that have been addressed with individual-based models. The authors then identify how the mechanics of building and using individual-based models differ from those of traditional science, and provide guidance on formulating, programming, and analyzing models. This book will be helpful to ecologists interested in modeling, and to other scientists interested in agent-based modeling.
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1996 with total page 822 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each issue is packed with extensive news about important cancer related science, policy, politics and people. Plus, there are editorials and reviews by experts in the field, book reviews, and commentary on timely topics.
Download or read book Principles of Epidemiology Workbook written by Ray Merrill and published by Jones & Bartlett Learning. This book was released on 2011-04-21 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by the best-selling author of Introduction to Epidemiology, this interactive workbook will engage your students in learning and prepare them to successfully evaluate public health programs and effectively communicate information that can inform public health officials and individuals. Divided into five chapters, the book covers assessment, disease etiology and investigation, clinical topics, evaluation, and communication. Definitions of statistical concepts and terms used in medical and epidemiologic literature are provided throughout. Perfect as a companion resource to any introductory Epidemiology text, Principles of Epidemiology Workbook provides an introduction to epidemiologic methodology for conducting public health assessment. Readers will come away with solid foundation of basic causal theory for identifying determinants of adverse health-related states or events and will gain a better understanding of the biological principles underlying the natural course of disease.
Download or read book Biological Engagement Programs Reducing Threats and Strengthening Global Health Security Through Scientific Collaboration written by Jeanne M. Fair and published by Frontiers Media SA. This book was released on 2017-09-13 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological engagement programs are a set of projects or activities between partner countries that strengthen global health security to achieve mutually beneficial outcomes. Engagement programs are an effective way to work collaboratively towards a common threat reduction goal, usually with a strong focus on strengthening health systems and making the world a safer place. Cooperative programs are built upon trust and sharing of information and resources to increase the capacity and capabilities of partner countries. Biological engagement programs reduce the threat of infectious disease with a focus on pathogens of security concern, such as those pathogens identified by the U.S. Government as Biological Select Agent and Toxins. These programs seek to develop technical or scientific relationships between countries to combat infectious diseases both in humans and animals. Through laboratory biorisk management, diagnostics, pathogen detection, biosurveillance and countermeasure development for infectious diseases, deep relationships are fostered between countries. Biological engagement programs are designed to address dual-use issues in pathogen research by promoting responsible science methodologies and cultures. Scientific collaboration is a core mechanism for engagement programs are designed to strengthen global health security, including prevention of avoidable epidemics; detection of threats as early as possible; and rapid and effective outbreak response. This Research Topic discusses Biological Engagement Programs, highlighting the successes and challenges of these cooperative programs. Articles in this topic outlined established engagement programs as well as described what has been learned from historical cooperative engagement programs not focused on infectious diseases. Articles in this topic highlighted selected research, trainings, and programs in Biological Engagement Programs from around the world. This Topic eBook first delves into Policies and Lessons Learned; then describes Initiatives in Biosafety & Biosecurity; the core of this work documents Cooperative Research Results from the field; then lastly the Topic lays out potential Future Directions to the continued success of the World’s cooperative science in reducing the threat of infectious diseases.
Download or read book Introduction to Structural Equation Modeling Using IBM SPSS Statistics and Amos written by Niels Blunch and published by SAGE. This book was released on 2012-11-09 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive Second Edition offers readers a complete guide to carrying out research projects involving structural equation modeling (SEM). Updated to include extensive analysis of AMOS′ graphical interface, a new chapter on latent curve models and detailed explanations of the structural equation modeling process, this second edition is the ideal guide for those new to the field. The book includes: Learning objectives, key concepts and questions for further discussion in each chapter. Helpful diagrams and screenshots to expand on concepts covered in the texts. Real life examples from a variety of disciplines to show how SEM is applied in real research contexts. Exercises for each chapter on an accompanying companion website. A new glossary. Assuming no previous experience of the subject, and a minimum of mathematical knowledge, this is the ideal guide for those new to SEM and an invaluable companion for students taking introductory SEM courses in any discipline. Niels J. Blunch was formerly in the Department of Marketing and Statistics at the University of Aarhus, Denmark
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1989 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2068 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book Regulation of Pesticides written by United States. Congress. House. Committee on Agriculture. Subcommittee on Department Operations, Research, and Foreign Agriculture and published by . This book was released on 1983 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Control of Carcinogens in the Environment written by United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Commerce, Transportation, and Tourism and published by . This book was released on 1983 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Introduction to Agent Based Modeling written by Uri Wilensky and published by MIT Press. This book was released on 2015-04-03 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and hands-on introduction to the core concepts, methods, and applications of agent-based modeling, including detailed NetLogo examples. The advent of widespread fast computing has enabled us to work on more complex problems and to build and analyze more complex models. This book provides an introduction to one of the primary methodologies for research in this new field of knowledge. Agent-based modeling (ABM) offers a new way of doing science: by conducting computer-based experiments. ABM is applicable to complex systems embedded in natural, social, and engineered contexts, across domains that range from engineering to ecology. An Introduction to Agent-Based Modeling offers a comprehensive description of the core concepts, methods, and applications of ABM. Its hands-on approach—with hundreds of examples and exercises using NetLogo—enables readers to begin constructing models immediately, regardless of experience or discipline. The book first describes the nature and rationale of agent-based modeling, then presents the methodology for designing and building ABMs, and finally discusses how to utilize ABMs to answer complex questions. Features in each chapter include step-by-step guides to developing models in the main text; text boxes with additional information and concepts; end-of-chapter explorations; and references and lists of relevant reading. There is also an accompanying website with all the models and code.
Download or read book Virus Dynamics Mathematical Principles of Immunology and Virology written by Martin Nowak and published by Oxford University Press, UK. This book was released on 2000-11-23 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking book describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients. It reveals fascinating insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. Structured around the examples of HIV/AIDS and hepatitis B, Nowak and May show how mathematical models can help researchers to understand the detailed dynamics of infection and the effects of antiviral therapy. Models are developed to describe the dynamics of drug resistance, immune responses, viral evolution and mutation, and to optimise the design of therapy and vaccines. - ;We know, down to the tiniest details, the molecular structure of the human immunodeficiency virus (HIV). Yet despite this tremendous accomplishment, and despite other remarkable advances in our understanding of individual viruses and cells of the immune system, we still have no agreed understanding of the ultimate course and variability of the pathogenesis of AIDS. Gaps in our understanding like these impede our efforts towards developing effective therapies and preventive vaccines. Martin Nowak and Robert M May describe the emerging field of theoretical immunology in this accessible and well- written text. Using mathematical modelling techniques, the authors set out their ideas about how populations of viruses and populations of immune system cells may interact in various circumstances, and how infectious diseases spread within patients. They explain how this approach to understanding infectious diseases can reveal insights into the dynamics of viral and other infections, and the interactions between infectious agents and immune responses. The book is structured around the examples of HIV/AIDS and Hepatitis B virus, although the approaches described will be more widely applicable. The authors use mathematical tools to uncover the detailed dynamics of the infection and the effects of antiviral therapy. Models are developed to describe the emergence of drug resistance, and the dynamics of immune responses, viral evolution, and mutation. The practical implications of this work for optimisation of the design of therapy and vaccines are discussed. The book concludes with a glance towards the future of this fascinating, and potentially highly useful, field of study. - ;... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host - Nature
Download or read book Library Information Science Abstracts written by and published by . This book was released on 2004 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt:
