Download or read book State of the Art in Quantitative Coronary Arteriography written by Johan H. C. Reiber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past twenty years, technical advances in coronary arteriography have contributed to our understanding of the pathophysiologic aspects and natural history of coronary artery disease. Probably more than 700. 000 coronary arterio grams are performed annually throughout the world. Usually, these arteriograms are interpreted visually to determine the morphologic extent and severity of coronary artery disease. These subjective determinations, which are hampered . by relatively large intra- and interobserver variations, are used as a basis for critically important therapeutic decisions: Which arteries are to be revascular ized, which lesions are suitable for coronary bypass surgery or for percutaneous coronary angioplasty? To improve on this clinical decision making, on the treat ment and follow-up of such patients, new, objective and reproducible techniques for the assessment of the extent and severity of coronary artery disease, both in terms of anatomy and functional significance of the lesions, must be made widely available. With such new procedures and technologies the efficacy of new thera peutic procedures, the effects of vasodilating and constricting drugs, and the results of long-term studies on the regression and progression of atherosclerotic plaque can be determined in an objective and cost-effective manner.

Download or read book Quantitative Coronary Arteriography written by Johan H. C. Reiber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: In June 1989, a third conference concentrating on the progress in quantita tive coronary angiography and related techniques was held in Rotterdam, again very successful as the two preceding events in 1985 and 1987. Tech nical as well as clinical aspects of digital and digitized coronarography, morphometry, parametric imaging and functional quantification of the human coronary circulation were presented and discussed by prominent exponents of those groups who have been active in this particular field for many years. This book contains the chapters representing the lectures held by leading experts during the symposium that update the knowledge currently available, including most recent aspects in angioscopy and intravascular ultrasound imaging. It also includes a historical review on the development of angiogra phic techniques from the very early days on to our times given by one of the pioneers in heart catheterization and angiography, Dr. Kurt Amplatz. Those who had the chance to listen to his talk, will surely remember his impressive, humorous lecture as one of the highlights of this meeting.

Download or read book Advances in Quantitative Coronary Arteriography written by Johan H. C. Reiber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 617 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this fourth book in the series on quantitative coronary arteriography (QCA) with the earlier three volumes published in 1986, 1988 and 1991, the latest developments in this exciting field are covered. Both the methodolog ical and clinical application aspects of these advances are presented in a comprehensive manner in a total of 37 chapters by world renowned experts. The book is subdivided into a total of eight parts, beginning with the more methodological issues, such as QCA and other modalities (3 chapters), cine film versus digital arteriography (3 chapters), quality control in QCA (4 chapters), and coronary blood flow and flow reserve (3 chapters). Since QCA has been well established as the technique for the assessment of regression and progression in atherosclerotic disease, and of restenosis after recanaliz ation procedures, major clinical trials in both groups are described extensively by their principal investigators in a total of 11 chapters. In addition, the QCA results after the application of various recanalization techniques are presented in another eight chapters. In the last part the experiences with various intracoronary prostheses with the emphasis on QCA are discussed in five chapters. This large increase in application oriented chapters means that QCA is well alive and gaining momentum. Although the accuracy and precision of the analytical methods steadily improve with the increasing complexity of the algorithms, there is still always the human factor involved in these processes in terms of frame selection, segment definition, etc.

Download or read book New Developments in Quantitative Coronary Arteriography written by Johan H. C. Reiber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are few techniques that have influenced therapeutic strategies in modem cardiology to a similar extent as coronary arteriography. Bypass surgery as well as transluminal coronary angioplasty would not have been possible without coronary angiography serving as a 'midwife' in their evolu tion. Despite the widespread and long-standing use in clinical practice, however, the interpretation of coronary angiograms has not changed very much since the early days. Most angiogr~s are still reviewed in a visual and semi-quantitative and thus often very subjective way. In the face of an almost exploding field for interventional catheterization including thrombolysis, balloon dilatation, and other rapidly evolving techniques for transluminal revascularization or recanalization, a more detailed and quantitative analysis of coronary arteriograms is urgently required. In addition to the delineation of coronary morphology, we need dynamic and functional information about flow and perfusion to understand the physiological significance of anatomic abnormalities. Coronary arteriography contains and can provide most of this information. With the application of appropriate techniques, it can be made available in the catheterization laboratory even during the patient's investiga tion, thus facilitating and improving clinical decision making. Objective and reproducible analysis will furthermore enhance our understanding about the pathophysiology of coronary disease.

Download or read book Progress in quantitative coronary arteriography written by Johan H. C. Reiber and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the fifth volume in this series on quantitative coronary arteriography (QCA) published over the last nine years. Research and applications in this exciting, field are covered in a total of 26 chapters by world renowned experts. This book is subdivided into a total of 6 parts, each emphasizing the latest progress in these respective fields. In Part One a comprehensive overview is given of the current knowledge and research in endothelial function, which is of eminent importance for the further understanding of the pathophysiology of coronary artery disease in patients. Fortunately, the use of QCA tools is not limited anymore to leading research institutes; over the last several years these tools have been installed in many cardiology centers world wide. To understand the current possibili ties, limitations and future expectations of QCA, several relevant topics are presented in Part Two. First of all, the questions about why and how QCA systems should be validated both at the development site and at the appli cation sites, and whether data from different vendors and core laboratories can be pooled, are discussed. As the X-ray cardiovascular world steadily moves into the digital imaging era, differences and similarities between the conventional cinefilm and the modern digital approaches are presented. Cur rently. the widespread use of digital imaging is still hindered by the lack of proper archival and exchange media. Requirements and possible solutions for this problem are handled in this section as well.

Download or read book Coronary Radiology written by Matthijs Oudkerk and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first monograph to focus exclusively on coronary radiology. It is particularly timely, given that the emergence of computed tomography and magnetic resonance imaging, coupled with improvements in both hard- and software, has made reproducible non-invasive coronary imaging a practical reality. A wide range of topics is addressed, including: quantitative angiography, intravascular and quantitative ultrasound, multislice and electron beam computed tomography, magnetic resonance coronary angiography and use of the coronary calcium score as an independent risk factor. All of the latest developments, such as non-invasive intracoronary thrombus imaging, are covered. Particular care has been taken to consider the common questions confronted in asymptomatic patients. The text is supported by high-quality color images of the coronary and cardiac anatomy.

Download or read book Advances in Imaging Techniques in Ischemic Heart Disease written by Ernst E. van der Wall and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there have been tremendous advances in cardiac imaging techniques covering the complete spectrum from echocardiography, nuclear cardiology, magnetic resonance imaging to contrast angiography. With respect to these noninvasive and invasive cardiac imaging modalities, marked technological developments have allowed the cardiologist to visualize the myocardium in a far more refined manner than conventional imaging was capable of. Echocardiography has extended its domain with intravascular ultrasound, cardiovascular nuclear imaging has added positron emission tomography to its line of research, magnetic resonance imaging has been broadened with magnetic resonance angiography and spectroscopy, and finally contrast angiograp hy has widened its scope with excellent quantitation programs. For all these imaging modalities it is true that the application of dedicated quantitative analytic software packages enables the evaluation of the imaging studies in a more accurate, reliable, and reproducible manner. It goes without saying that these extensions and achievements have resulted in improved diagnostics and subsequently in improved patient care. Particularly in patients with ischemic heart disease, major progress has been made to detect coronary artery disease in an early phase of the disease process, to follow the atherosclerotic changes in the coronary arteries, to establish the functional and metabolic consequences of the luminal obstructions, and to accurately assess the results of interventional therapy.

Download or read book Analysis and Simulation of the Cardiac System Ischemia written by Rafael Beyar and published by CRC Press. This book was released on 2020-10-28 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over thiry-five experts contribute to this publication about the various interactions and interrelationships of the parameters which affect the normal and ischemic heart. Mechanical aspects related to the global and regional function of the heart are discussed. Coronary perfusion of the ischemic heart is considered, with emphasis on the effects of reperfusion. Electrical activation, formation of arrhythmias, and the effects of ischemia or ionic transport in the myocardium are presented. Metabolic aspects of the ischemic heart, including calcium transport, are also explained.

Download or read book Atherosclerotic Plaques written by Robert W. Wissler and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: The philosophy of this NATO Advanced Research Workshop and the monograph it has yielded is that if you put a small number of very talented and creative scientists of different backgrounds and documented accomplishments together in a cloistered place for a few days to consider a very important and timely topic, many new ideas will be generated. The keynote of this conference was the Future. By this we mean the expected future developments of highly reliable sequential quantitative measurements of atherosclerotic plaque size and components in living human subjects. Some of the best minds and the most experienced and talented individuals at the leading edges of imaging of arteries were involved; some of the best scientists and students of the atherosclerotic plaque and its components participated; and some of the leading investigators of the cell biology or, as we call it in the USA, the pathobiology of atherosclerosis, contributed important new information. All of these individuals were actively involved in the conference and each obviously had carefully prepared and was able to communicate effectively.

Download or read book Modalities written by Leondes and published by CRC Press. This book was released on 1997-12-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of modalities has been revolutionized by powerful new computational techniques in image processing, with applications such as Computer-Aided Tomography (CAT) and Magnetic Resonance Imaging (MRI), among others. It is, therefore, an appropriate topic to be included in this series that studies the marriage of computer capabilities and medical imaging, exemplifying a significant illustration of relatively recent, valuable technologies known as the second industrial revolution. Examines the issues, challenges, technology, and progress of 3-D imaging, SPECT reconstruction, gastrointestinal endoscopy, and EIT. Also explores the techniques, methods and issues involving accurate quantification of neuroreceptor-binding radioglands, and reconstructing images from the four types of incompleteness that arise in computed tomography: truncated projections, hollow projections, limited angle coverage, and arbitrarily missing values in a projection. This book clearly reveals the effectiveness and gre

Download or read book Echocardiography in Coronary Artery Disease written by Cees Visser and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some 25 years ago, the coronary care unit concentrated high technology and the acutely ill patients who might benefit from it in a single, recognizable space. Since then, that space and its technical equipment have changed, as has part of its population. Acute ischemia, silent and manifest, occurs within and outside of the coronary care unit as pain, arrhythmia, or pump failure. Its detection and treatment require the utilization of many diagnostic techniques and skills, not the least of which is two-dimensional Doppler echocardio graphy, which is gaining importance. Future developments, in tandem with computer technology, may add to this importance by enabling tissue identification, spatial representation, and Doppler flow mapping. This book describes the state of the art for the practicing clinician using Doppler echocardi?graphy at the bedside of patients with acute ischemic manifestations of coronary heart disease. The first requirement is to move from the echo laboratory to the coronary care unit, emergency department, operating room, or catheterization laboratory, using equipment suited for that purpose. The second, more trying imperative is to secure good cooper Ition between those treating the acutely ill patient and the investigator who interferes with his probes. If successful ceeding in both, rewarding results can be obtained, since echocardiography is a very sensitive and specific tool for recognizing and quantifying early ischemia.

Download or read book Clinical Echocardiography written by M. Iwase and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently, much progress has been made with echocardiography and Doppler techniques and these ultrasound methods have grown in importance and reliability as non-invasive diagnostic procedures for many cardiovascular disorders. The objective of this t~xtbook is to offer a detailed yet concise overview of the echocardiographic diagnosis of the various cardiovascular diseases. The book focuses upon the practical echocardiographic (including Doppler) exam ination. Accordingly, the fundamental principles of echocardiography and the Doppler techniques (pulsed and continuous wave and color flow mapping are covered briefly but comprehensively). A copious amount of representative figures and illustrations is included so that the reader is able to understand the clinical application of each modality in the various cardiovascular pathologies and the echocardiographic diagnosis. In keeping with the concept of an integrated echocardiographic examination, the two-dimensional, M-mode and Doppler echocardiographic findings are included in many of the diseases. Usually, the echocardiographic examination is approached first by two-dimensional imag ing to give an understanding of the anatomical correlations, if necessary adding M-mode to clarify the time course of intracardiac movements, and secondly by each Doppler technique to evaluate the hemodynamic conditions. When familiar with these approaches, one can make not only the diagnosis of many cardiovascular diseases with echocardiography alone, but also the rational and expeditious management of patients. Today, some of the cardiac diseases (Atrial Myxoma, Atrial Septal Defect, Infective endocarditis and so forth) have been oper ated based only on echocardiographic findings.

Download or read book Final Report Sources and documentation written by United States. Advisory Committee on Human Radiation Experiments and published by . This book was released on 1995 with total page 916 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Databases for Cardiology written by G.T. Meester and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: A database is in principle just a large collection of related or separate data, systematically stored in a computer. It should be possible for the data to be easily entered into the database-structure and afterwards also easily read, corrected and processed. The later analysis of data from such a database is greatly enhanced by the availability of special query languages and statistical analysis programs, not only for serial items but also for large combinations of data. Query languages, such as SQL (Structured Query Language) developed especially for these purposes, make databases easily accessible, also to researchers who may not be very well versed in computer programming. The cardiological/medical clinician and researcher of today is of necessity confronted more and more with computer-based data storage. Interest is of course focused primarily on the clinical use of such databases more than on the technical design itself, except for some very specific, personalized applications. For the latter approach, there are at present many software packages commercially available, especially designed for use in the personal computer environment. This book is comprised out of a number of contributions by various authors with differing backgrounds and from many different countries. The editors, being a cardiologist and an information scientist, have strived to achieve an equilibrium between these two fields. The chapters in this book form a cross-section of the many approaches to database design and implementation in the area of cardiology.

Download or read book Coronary Circulation written by J.A. Spaan and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few diagnostic methods in Cardiology have heralded such revolutionary developments as the introduction of coronary arteriography. When, in the early 1960's, Dr. F. Mason Sones demonstrated that visualization of the coronary anatomy in living humans was not only feasible but sufficiently safe and reliable to be used as a clinical tool in the evaluation of patients with known or suspected ischemic heart disease, the thus far somewhat neglected area of coronary circulation became the focus of interest. Naturally, for a considerable period of time a great deal of emphasis was placed upon coronary anatomy. Simple relations between narrowing lesions, impediment to flow, and prognosis were assumed to exist. Spectacular results of surgical coronary revascularization seemed to confirm this concept. Gradually it has become evident that the pathophysiology of coronary artery disease is considerably more complex. Diagnostic methods were introduced to assess and quantify exercise-induced myocardial ischemia. At first, these tests were used mainly to achieve a more discriminative selection of candidates for coronary arteriography and the coronary arteriogram remained the gold standard. Currently, these techniques have evolved to the point where they provide valuable functional and metabolic information. They have become powerful independent tools in clinical investigations and evaluation of individual patients.

Download or read book Cardiovascular Disease in the Elderly written by Franz H. Messerli and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 387 pages. Available in PDF, EPUB and Kindle. Book excerpt: By the time a man gets well into his seventies, his continued existence is a mere miracle. -Robert Louis Stevenson It hardly seems possible that a second edition is needed after the first has been in print for only three years. However, when I reflect on what has happened in geriatric cardiology during that short period, it becomes obvious why. First, cardiologists all over the globe have begun to realize that geriatric cardiology has evolved into a science and a clinical discipline of its own. Although some of us may consider such subspecialization unfortunate, it has become clear that a variety of cardiac disorders present with different symptoms and signs, require a different diagnostic and therapeutic approach, and have a different prognostic outlook in the elderly when compared to middle-aged patients. Since the aging segment of the population has increased dramatically over the past few decades, and continues to do so, specific age-related disorders are more frequently encountered by the practicing physician, be it by the general practitioner, by the internist, or by a cardiologist. Cardiovascular Disease in the Elderly provides an up-to-date guide to help the physician deal with these problems, leading the way in what turns out to be an increasingly complex area. Second, I have been heartened by the warm reception of the first edition and by the excellent reviews that it got in the most prestigious medical journals.

Download or read book Cardiovascular Drug Therapy in the Elderly written by Adam Schneeweiss and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular drug therapy has markedly progressed in the recent decades. Not only have new drugs been introduced to clinical practice, but new classes of drugs have been developed. While in 1960 the practicing cardiolo gist had a selection of about only ten drugs, in 1987 about 150 drugs are routinely used in cardiovascular diseases. Elderly patients, however, usually do not enjoy the full benefit of this progress. This might be due to lack of knowledge, a conservative approach, or the worldwide tendency not to try new drugs in the elderly. It is now clear that the majority of patients that will be treated in car diovascular clinics will be, in the near future, elderly patients. Even now, elderly patients form about one-third of the patients with cardiovascular diseases. These patients are approached, however, according to criteria devel oped for younger populations. This is despite the fact that elderly patients differ from younger ones in most aspects, including pathology, epidemiol ogy, pathophysiology, diagnostic approach, management, pharmacology, pharmacokinetics, rehabilitation, and supportive treatment. It is the purpose of this book to present to the clinician all drugs with which there is clinical experience in the elderly or which might be potentially useful for the elderly with cardiovascular diseases. The data are presented without the authors taking a position. This should allow the clinicians to make their own selection and individualize treatment, vii viii Preface based on a wide data base. Comparative data are presented only when specific comparative studies were performed.