Download or read book Spongiform Degeneration of the Gerbil Cochlear Nucleus written by Brian Thomas Faddis and published by . This book was released on 1994 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book From Development to Degeneration and Regeneration of the Nervous System written by Charles E. Ribak and published by Oxford University Press. This book was released on 2009 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides current information about the three areas mentioned in the title: Neuronal Migration and Development, Degenerative Brain Diseases, and Neural Plasticity and Regeneration. The chapters about brain development examine the cellular and molecular mechanisms by which neurons are generated from the ventricular zone in the forebrain and migrate to their destinations in the cerebral cortext. This description of cortical development also includes a discussions of the Cajal-Retzius cell. Another chapter provides insight about the development of another forebrain region, the hypothalamus. The remaining chapters of this section examine the clinical relevance of brain development in certain disease states in humans: neural tube defects and the normal and abnormal development of human electroencephalographic recordings during the first year of age.The second section on degenerative disorders of the brain begins wtih details about the dopaminergic neurons in the substantia niger and their loss in Parkinson's disease. Two subsequent chapters describe changes in brain aging, including changes in the numbers of myelinated axons. Other chapters in this section describe important cellular and molecular changes found in Alzheimer's disease and human epilepsy. Together, these chapters summarize much of our current knowledge about the major molecular and cellular changes found in several degenerative diseases of the brain.The last section addresses the issues of brain plasticity and regeneration in the adult brain and begins with a chapter on how the brain's own stem cells provide newly generated neurons to the hippocampal dentate gyrus and how these neurons become integrated into neural circuitry. The following two chapters examine some of the neuroplastic changes that take place in motor and sensory cortices of awake behaving primates. The concluding two chapters address the issue of regeneration in the injured spinal cord and the factors that may contribute to its success.

Download or read book Hearing Loss written by Sadaf Naz and published by BoD – Books on Demand. This book was released on 2012-03-28 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Authored by 17 international researchers and research teams, the book provides up-to-date insights on topics in five different research areas related to normal hearing and deafness. Techniques for assessment of hearing and the appropriateness of the Mongolian gerbil as a model for age-dependent hearing loss in humans are presented. Parental attitudes to childhood deafness and role of early intervention for better treatment of hearing loss are also discussed. Comprehensive details are provided on the role of different environmental insults including injuries in causing deafness. Additionally, many genes involved in hearing loss are reviewed and the genetics of recessively inherited moderate to severe and progressive deafness is covered for the first time. The book also details established and evolving therapies for treatment of deafness.

Download or read book Rodent Bioacoustics written by Micheal L. Dent and published by Springer. This book was released on 2018-08-28 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: By far, the most widely used subjects in psychological and biological research today are rodents. Although rats and mice comprise the largest group of animals used in research, there are over 2,000 species and 27 families of rodents, living all over the world (except Antarctica) and thriving in many different habitat types. The vast environmental diversity that rodents face has led to numerous adaptations for communication, including vocalizing and hearing in both the sonic and ultrasonic ranges, effectively communicating in the open air and underground, and using vocalizations for coordinating sexual behavior, for mother-pup interactions, and for signaling an alarming situation to the group. Some rodent species have even developed foot drumming behaviors for communication. Comparative studies from around the globe, using both field and laboratory methodologies, reveal the vast differences in acoustic communication behavior across many rodent species. Some rodents are amenable to training and have been domesticated and bred purely for research purposes. Since the early 1900s, rats and mice have been indispensable to research programs around the world. Thus, much of what we know about hearing and vocalizations in rodents come from these two species tested in the laboratory. The sequencing of the mouse genome in 2002, followed by the rat genome in 2004, only increased the utility of these animals as research subjects since genetically engineered strains mimicking human diseases and disorders could be developed more easily. In the laboratory, rats and mice are used as models for human communication and hearing disorders and are involved in studies on hearing loss and prevention, hormones, and auditory plasticity, to name a few. We know that certain strains of mice retain hearing better than others throughout their lifespan, and about the genes involved in those differences. We know about the effects of noise, hormones, sex, aging, and circadian rhythms on hearing in mice and other rodents. We also know about normal hearing in many families of rodents, including the perception of simple and complex stimuli and the anatomy and physiology of hearing and sound localization. The importance of acoustic communication to these animals, as well as the significance of these mammals to biomedical research, are summarized in the chapters.

Download or read book Functional Neurobiology of Aging written by Patrick R. Hof and published by Elsevier. This book was released on 2001-01-11 with total page 989 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments. - Organized by function, making it easy to find and understand the material - Addresses impairments both associated with diseases and not associated with diseases - Written by leading researchers in the field - Most comprehensive source of information on the neurobiology of aging

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1998 with total page 1646 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Models of Seizures and Epilepsy written by Asla Pitkänen and published by Elsevier. This book was released on 2005-10-04 with total page 705 pages. Available in PDF, EPUB and Kindle. Book excerpt: An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy. Chapters cover a broad range of experimental approaches (from in vitro to whole animal preparations), a variety of epileptiform phenomenology (including burst discharges and seizures), and suggestions for model characterization and validation, such as electrographic, morphologic, pharmacologic, and behavioral features. Experts in the field provide not only technical reviews of these models but also conceptual critiques - commenting on the strengths and limitations of these models, their relationship to clinical phenomenology, and their value in developing a better understanding and treatments. Models of Seizures and Epilepsy is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models for addressing key questions in the field. It also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research. - The first comprehensive description of animal models of epilepsy since the early 1970's - Comprehensive analysis of "What the models model" to guide the selection of each model, and what specific questions it will answer - Elegant examples of the use of novel technologies that can be applied in experimental epilepsy research - World expert opinions on the clinical relevance of each model

Download or read book Pathology of Laboratory Rodents and Rabbits written by Stephen W. Barthold and published by John Wiley & Sons. This book was released on 2016-01-04 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fourth edition, Pathology of Laboratory Rodents and Rabbits has become a standard text for veterinary pathologists, laboratory animal veterinarians, students, and others interested in these species. • The standard reference on the pathogenesis and cardinal diagnostic features of diseases of mice, rats, hamsters, gerbils, guinea pigs, and rabbits • Expanded coverage of rabbit disease, normal anatomic features, and biology • Over 450 color photographs illustrating gross and microscopic pathology • Companion website offering images from the text in PowerPoint

Download or read book Abstracts Society for Neuroscience written by Society for Neuroscience and published by . This book was released on 1994 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Download or read book CSA Neurosciences Abstracts written by and published by . This book was released on 1997 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Laboratory Animal Medicine written by Lynn C. Anderson and published by Elsevier. This book was released on 2015-07-04 with total page 1727 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animal Medicine, Third Edition, is a fully revised publication from the American College of Laboratory Medicine's acclaimed blue book series. It presents an up-to-date volume that offers the most thorough coverage of the biology, health, and care of laboratory animals. The book is organized by species, with new inclusions of chinchillas, birds, and program and employee management, and is written and edited by known experts in the fields. Users will find gold-standard guidance on the study of laboratory animal science, as well as valuable information that applies across all of the biological and biomedical sciences that work with animals. - Organized by species for in-depth understanding of biology, health, and best care of animals - Features the inclusion of chinchillas, quail, and zebra finches as animal models - Offers guidance on program and employee management - Covers regulations, policies, and laws for laboratory animal management worldwide

Download or read book Society for Neuroscience Abstracts written by Society for Neuroscience. Meeting and published by . This book was released on 1997 with total page 1548 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Excerpta Medica written by and published by . This book was released on 1991 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Principles of Animal Research for Graduate and Undergraduate Students written by Mark A. Suckow and published by Academic Press. This book was released on 2016-11-16 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher's education. - Provides background material for students to understand the broader backdrop against which animal research is undertaken - Includes ethical and regulatory information - Covers commonly used animal models and the process to choose a model for biomedical research

Download or read book Tinnitus written by James Byron Snow and published by PMPH-USA. This book was released on 2004 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Accompanying CD-ROM contains the complete text and illustrations contained within the text, in fully searchable PDF files.

Download or read book Auditory neuroanatomy A sound foundation for sound processing written by Miguel A. Merchán and published by Frontiers E-books. This book was released on with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last two decades, the ever increasing pace of auditory research has generated an undreamed of knowledge about the molecular and cellular bases of hearing, the physiopathology of hearing loss, the activity of the brain evoked by sounds, and the possibilities of imaginative strategies to restore hearing. The aim of this Research Topic is to contribute to the development of auditory neuroscience by placing in an up-to-date morphological context some of the latest developments in the field. This Research Topic for Frontiers in Neuroanatomy will consist of peer-reviewed articles dealing with the development, evolution, function and plasticity of the auditory system through a broad range of anatomical approaches. Articles combining neuroanatomy with other disciplines, such as molecular biology, genetics, physiology, pharmacology, behavior, neuroimaging, clinical medicine or bioinformatics, will be considered for publication insofar as they contribute to the understanding of the structure of the auditory regions of the central nervous system. The authors of the papers published in this Research Topic will be invited to present and discuss their results during a symposium organized by the Instituto de Neurociencias of Castilla y León (INCyL), to be held in Salamanca, Spain, in 2010.