Download or read book Species and Specificity written by Pauline M. H. Mazumdar and published by Cambridge University Press. This book was released on 2002-07-18 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: An account of scientific disputes over the core problems of research and practice in immunology.
Download or read book Species and Specificity written by Pauline Margaret Hodgson Mazumdar and published by . This book was released on 1995 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Their science was designed only in part to wrest an answer from nature: it was at least as important to wring an admission of defeat from their opponents. One of the key figures in the debate was the Austrian immunochemist Karl Landsteiner, whose career provides the central focus for Mazumdar's account. His unitarian views excluded him from promotion within European institutions, where the specificity and pluralism espoused by Robert Koch and Paul Ehrlich were entrenched. Landsteiner himself was forced into a kind of exile at Rockefeller University in New York. Though Landsteiner won a Nobel prize for his work, his inability to gain more widespread acceptance of his views caused him to view his life as a failure.
Download or read book Evolution of Design Features in the Coding of Species Specificity written by Masakazu Konishi and published by . This book was released on 1970 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Species specificity in fertilization reaction written by Tore Hultin and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Species Specificity in Peptide Elongation written by Robert Kovelman and published by . This book was released on 1970 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book The Pangenome written by Hervé Tettelin and published by Springer Nature. This book was released on 2020-04-30 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.
Download or read book The Specificity of Serological Reactions written by Karl Landsteiner and published by Courier Corporation. This book was released on 2013-09-25 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nobel prizewinner's account of experiments he and colleagues carried out on antigens and serological reactions with simple compounds. Exceptionally broad coverage of basic immunology. Extensive bibliography.
Download or read book Chimpanzees in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 2011-12-05 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Download or read book Organ and Species Specificity in Chemical Carcinogenesis written by Robert Langenbach and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Symposium on Organ and Species Specificity in Chemical Carcinogenesis was held March 1981 in Raleigh, North Carolina. Dr. James Miller concluded this Symposium with these remarks: "Without a doubt all of us would agree this has been a very successful symposium in illustrating a very wide range of chemical, stereochemical, biochemical, metabolic, molecular, and biological factors in chemical carcinogenesis. I think it is noteworthy that many of the discussions have dealt with pharmacodynamic, or toxicodynamic, factors that can influence the biological activities of the extremely wide range of structures that we choose to call chemical carcinogens. I sincerely hope that after this symposium everyone here will realize the very great need we have for further information on these agents in the species we profess to be working for, the human species. We badly need an adequate data base on human organs, human tissues, human cells, human subcellular preparations, and human body fluids. I don't think we can rely on extrapolations of data on chemical carcinogenesis from experimental animals to humans, no matter how sophisticated or plausible these extrapolations may seem, until we know far more about chemical carcinogenesis in humans. Now, I'd like to add a somewhat personal note. As many of you know, my wife and I have shared a joint career of some 40 years in this field, and I'd like to emphasize in these closing remarks the factor of youth.
Download or read book Joint Species Distribution Modelling written by Otso Ovaskainen and published by Cambridge University Press. This book was released on 2020-06-11 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive account of joint species distribution modelling, covering statistical analyses in light of modern community ecology theory.
Download or read book Scientific Frontiers in Developmental Toxicology and Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 2000-12-21 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.
Download or read book Obligate Pollination Mutualism written by Makoto Kato and published by Springer. This book was released on 2017-05-09 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a comprehensive overview of our current understanding of mutualism origin, plant–pollinator specificity, mutualism stability, and reciprocal diversification. In particular, it focuses on the natural history and evolutionary history of the third example of obligate pollination mutualism, leafflower–leafflower moth association, which was discovered in the plant family Phyllanthaceae by the lead editor and then established by the editors and their coworkers as an ideal model system for studies of mutualism and the coevolutionary process. This work brings together the knowledge they have gained through an array of research conducted using different approaches, ranging from taxonomy, phylogenetics, ecology, and evolutionary biology to biogeography. Richly illustrated with numerous original color photographs, the volume consists of 13 chapters and is divided into three main parts: natural history, ecology, and evolution. It begins by showcasing numerous examples of plant–animal interactions and their origins to guide readers in the world of leafflowers and their pollinators. The immense diversity of Phyllanthaceae and pollinator moths is then explored, and in the following 7 chapters mutualism is discussed from a range of ecological and evolutionary points of view. The final chapter presents a review of the evolution and variety of obligate pollination mutualisms. This book offers researchers and students in the field of ecology, botany, evolutionary biology, pollination biology, entomology, and tropical biology fascinating insights into why such a costly pollination system has evolved and why Phyllanthaceae is so diverse despite the inconspicuousness of their flowers.
Download or read book The Immunoglobulins written by Roald Nezlin and published by Academic Press. This book was released on 1998-05-06 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive up-to-date information on the structure and function of immunoglobulins. It describes the basic features of these molecules, which assists the reader in understanding how they function as an integral part of the immune system. The Immunoglobulins describes the localization and structure of different binding sites of immunoglobulin molecules, including the antigen-binding site, on the basis of latest x-ray crystallography studies. It discusses recently developed biotechnological methods that allow scientists to obtain fully active antibody molecules in vitro even without immunization and to construct new variants of immunoglobulins and their fragments by fusing with various other active molecules. A survey of recent knowledge on immunoglobulin-binding molecules other than antigens and on flexibility of immunoglobulin molecules concludes the discussion of functional aspects of the problem. - Describes recent reviews on the structure and function of immunoglobulin molecules of various species - Summarizes in detail recent findings on the fine structure of the antigen-combining site - Presents comparative data on the antigen-recognizing sites of other molecules such as MHC proteins and T-cell receptors - Summarizes growing data on immunoglobulin binding sites responsible for the reaction of immunoglobulins with molecules other than antigens - Explores the rapid advance of recent biotechnological methods used for the construction of antibody molecules and their fragments with new properties - Presents extensive references and is lavishly illustrated
Download or read book Differentation and Specificity of Starches in Relation to Genera Species Etc written by E. T. Reichert and published by . This book was released on 1913 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tupai written by Louise H. Emmons and published by Univ of California Press. This book was released on 2000-12-12 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treeshrews suffer from chronic mistaken identity: they are not shrews, and most are not found in trees. These squirrel-sized, brownish mammals with large, dark, lashless eyes were at one time thought to be primates. Even though most scientists now believe them to belong in their own mammalian order, Scandentia, they still are thought to resemble some of the earliest mammals, which lived alongside the dinosaurs. This book describes the results of the first comparative study of the ecology of treeshrews in the wild. Noted tropical mammalogist Louise H. Emmons conducted this pathbreaking study in the rainforests of Borneo as she tracked and observed six species of treeshrews. Emmons meticulously describes their habitat, diet, nesting habits, home range, activity patterns, social behavior, and many other facets of their lives. She also discusses a particularly interesting aspect of treeshrews: their enigmatic parental care system, which is unique among mammals.
Download or read book The Neurobiology of Olfaction written by Anna Menini and published by CRC Press. This book was released on 2009-11-24 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Overview of Advances in OlfactionThe common belief is that human smell perception is much reduced compared with other mammals, so that whatever abilities are uncovered and investigated in animal research would have little significance for humans. However, new evidence from a variety of sources indicates this traditional view is likely
