Download or read book Special Topic Domino Reactions Tandem Transformations in Organic Synthesis written by Erick M. Carreira and published by . This book was released on 2012 with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Applications of Domino Transformations in Organic Synthesis Volume 1 written by Prof. Scott A. Snyder and published by Thieme. This book was released on 2015-11-18 with total page 1121 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals. "Science of Synthesis: Applications of Domino Transformations in Organic Synthesis" explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others. Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.
Download or read book Applications of Domino Transformations in Organic Synthesis Volume 2 written by Prof. Scott A. Snyder and published by Thieme. This book was released on 2015-11-18 with total page 805 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals. "Science of Synthesis: Applications of Domino Transformations in Organic Synthesis" explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others. Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.
Download or read book Domino Reactions written by Lutz F. Tietze and published by John Wiley & Sons. This book was released on 2013-12-23 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: The follow-up to the successful "Domino Reaction in Organic Synthesis", this ready reference brings up to date on the original concept. The chapters have been arranged according to the name of well-known transformations of the first step and in combination with the formed products. Each chapter is written by an internationally renowned expert, and the book is edited by L. F. Tietze, who established the concept of domino reactions. The one-stop source for all synthetic chemists to improve the synthetic efficiency and allow an ecologically and economically beneficial preparation of every chemical compound.
Download or read book Applications of Domino Transformations in Organic Synthesis Workbench Edition written by Scott A. Snyder and published by Thieme Chemistry. This book was released on 2016-05-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals. Science of Synthesis: Applications of Domino Transformations in Organic Synthesis explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others. Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements. Volume 2 covers pericyclic reactions (Diels-Alder, sigmatropic shifts, ene reactions), dearomatizations, and additions to C-O/C-N multiple bonds.
Download or read book Applications of Domino Transformations in Organic Synthesis written by Daniel Adu-Ampratwum and published by Thieme Chemistry. This book was released on 2016 with total page 732 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals. "Science of Synthesis: Applications of Domino Transformations in Organic Synthesis" explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others. Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements.
Download or read book Stereoselective Multiple Bond Forming Transformations in Organic Synthesis written by Jean Rodriguez and published by John Wiley & Sons. This book was released on 2015-04-08 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Combining the important research topic of multiple bond-forming transformations with green chemistry, this book helps chemists identify recent sustainable stereoselective synthetic sequences. • Combines the important research topic of multiple bond-forming transformations with green chemistry and sustainable development • Offers a valuable resource for preparing compounds with multiple stereogenic centers, an important field for synthetic chemists • Organizes chapters by molecular structure of final products, making for a handbook-style resource • Discusses applications of the synthesis of natural products and of drug intermediates • Brings together otherwise-scattered information about a number of key, efficient chemical reactions
Download or read book Domino Reactions in Organic Synthesis written by Lutz F. Tietze and published by John Wiley & Sons. This book was released on 2006-12-13 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: Domino reactions enable you to build complex structures in one-pot reactions without the need to isolate intermediates- a dream comes true. In this book, the well-respected expert, Professor Lutz Tietze, summarizes the possibilities of this reaction type - an approach for an efficiant, economically benificial and ecological benign synthesis. A definite must for every organic chemist.
Download or read book Applications of Domino Transformations in Organic Synthesis written by Scott A. Snyder and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycoscience written by Zbigniew J. Witczak and published by John Wiley & Sons. This book was released on 2016-01-07 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book consists of a brief introduction, a foreward provided by professor Danishefsky of Columbia University, and about 14 - 16 chapters, each written by one or two eminent scholars/authors describing their recent research in the area of either domino reactions or intramolecular rearrangements in carbohydrate chemistry. Three or four chapters will be reviews. The domino (cascade, tandem) reactions are always intramolecular. They are usually very fast, clean and offer highly complex structures in a one pot process. Intramolecular rearrangements offer very similar advantages and often lead to highly complex products as well. Although many recently isolated carbohydrates fulfill various sophisticated functions, their structures are often very complex. The editors cover the broadest scope of novel methodologies possible. All the synthetic and application aspects of domino/cascade reactions are explored in this book. A second theme that will be covered is intramolecular rearrangement, which is also fast, stereoselective, and often constitutes one or more steps of domino / cascade process. Selected examples of intramolecular rearrangements are presented. Together, both processes offer an elegant and convenient approach to the synthesis of many complex molecules, which are normally difficult to synthesize via alternative routes. It appears that domino and intramolecular rearrangements are ideally suited to synthesize certain specific modified monosaccharides. What is particularly important is that both processes are intermolecular and almost always yield products with very well-defined stereochemistry. This high definition is absolutely crucial when synthesizing advanced, modified mono and oligosaccharides. The choice of contributors reflects an emphasis on both therapeutic and pharmacological aspects of carbohydrate chemistry.
Download or read book Asymmetric Domino Reactions written by Helene Pellissier and published by Royal Society of Chemistry. This book was released on 2013-03-13 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest developments in asymmetric domino reactions, focussing on those published in the last 6 years. These fascinating reactions have rapidly become one of the most current fields in organic chemistry, since they allow reaching easily high molecular complexity in an economically favourable way with advantages of savings in solvent, time, energy, and costs. Unsurprisingly, the high levels of efficiency and enantioselectivity generally reached in these reactions have been exploited for the production of a wide number of complex chiral molecules with dense stereochemistry and functionality, which are motifs present in biologically active compounds and natural products. The book is divided into three principal sections, dealing successively with asymmetric domino reactions based on the use of chiral auxiliaries, asymmetric domino reactions based on the use of chiral metal catalysts, and asymmetric domino reactions based on the use of chiral organocatalysts, covering the literature since the beginning of 2006.
Download or read book Catalytic Cascade Reactions written by Peng-Fei Xu and published by John Wiley & Sons. This book was released on 2013-12-30 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Demonstrates the advantages of catalytic cascade reactions for synthesizing natural products and pharmaceuticals Riding the wave of green chemistry, catalytic cascade reactions have become one of the most active research areas in organic synthesis. During a cascade reaction, just one reaction solvent, one workup procedure, and one purification step are needed, thus significantly increasing synthetic efficiency. Featuring contributions from an international team of pioneers in the field, Catalytic Cascade Reactions demonstrates the versatility and application of these reactions for synthesizing valuable compounds. The book examines both organocatalysis and transition-metal catalysis reactions, bringing readers up to date with the latest discoveries and activities in all major areas of catalytic cascade reaction research. Catalytic Cascade Reactions begins with three chapters dedicated to organocatalytic cascade reactions, exploring amines, Brønsted acids, and the application of organocatalytic cascade reactions in natural product synthesis and drug discovery. Next, the book covers: Gold-catalyzed cascade reactions Cascade reactions catalyzed by ruthenium, iron, iridium, rhodium, and copper Palladium-catalyzed cascade reactions of alkenes, alkynes, and allenes Application of transition-metal catalyzed cascade reactions in natural product synthesis and drug discovery Engineering mono- and multifunctional nanocatalysts for cascade reactions Multiple-catalyst-promoted cascade reactions All chapters are thoroughly referenced, providing quick access to important original research findings and reviews so that readers can explore individual topics in greater depth. Drawing together and analyzing published findings scattered across the literature, this book provides a single source that encapsulates our current understanding of catalytic cascade processes. Moreover, it sets the stage for the development of new catalytic cascade reactions and their applications.
Download or read book Applications of Domino Transformations in Organic Synthesis written by Daniel Adu-Ampratwum and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Science of Synthesis written by Scott A. Snyder and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Asymmetric Metal Catalysis in Enantioselective Domino Reactions written by Helene Pellissier and published by John Wiley & Sons. This book was released on 2019-11-11 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduces an innovative and outstanding tool for the easy synthesis of complex chiral structures in a single step Covering all of the literature since the beginning of 2006, this must-have book for chemists collects the major progress in the field of enantioselective one-, two-, and multicomponent domino reactions promoted by chiral metal catalysts. It clearly illustrates how enantioselective metal-catalyzed processes constitute outstanding tools for the development of a wide variety of fascinating one-pot asymmetric domino reactions, thereby allowing many complex products to be easily generated from simple materials in one step. The book also strictly follows the definition of domino reactions by Tietze as single-, two-, as well as multicomponent transformations. Asymmetric Metal Catalysis in Enantioselective Domino Reactions is divided into twelve chapters, dealing with enantioselective copper-, palladium-, rhodium-, scandium-, silver-, nickel-, gold-, magnesium-, cobalt-, zinc-, yttrium and ytterbium-, and other metal-catalyzed domino reactions. Most of the chapters are divided into two parts dealing successively with one- and two-component domino reactions, and three-component processes. Each part is subdivided according to the nature of domino reactions. Each chapter of the book includes selected applications of synthetic methodologies to prepare natural and biologically active products. -Presents the novel combination of asymmetric metal catalysis with the concept of fascinating domino reactions, which allows high molecular complexity with a remarkable level of enantioselectivity -Showcases an incredible tool synthesizing complex and diverse chiral structures in a single reaction step -Includes applications in total synthesis of natural products and biologically active compounds -Written by a renowned international specialist in the field -Stimulates the design of novel asymmetric domino reactions and their use in the synthesis of natural products, pharmaceuticals, agrochemicals, and materials Asymmetric Metal Catalysis in Enantioselective Domino Reactions will be of high interest to synthetic, organic, medicinal, and catalytic chemists in academia and R&D departments.
Download or read book Non Conventional Synthesis written by György Keglevich and published by Walter de Gruyter GmbH & Co KG. This book was released on 2023-11-06 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-conventional synthetic methods may provide new and green methods for the preparation of bioactive heterocycles. These methods, such as microwave and ultrasound assisted synthesis, biocatalysis, photochemistry and electrosynthesis use less energy and may produce less waste to get the desired products when compared to traditional methods. This book explores the use of these methods when synthesizing various biologically relevant heterocyclic scaffolds. THE SERIES: GREEN BIOACTIVE HETEROCYCLES Heterocycles are a widely utilized group of molecules as they often contain bioactivity that is useful in drug development, agriculture, and other applications. However, their synthesis remains challenging with diffi cult to control functional groups. With a greater focus on sustainable synthesis practices, there is a need to develop greener synthetic methods for the synthesis of structurally diverse bioactive heterocyclic scaffolds. This series aims to do so, by collecting developments into common themes.
Download or read book Organic Synthesis Using Samarium Diiodide written by David J. Procter and published by Royal Society of Chemistry. This book was released on 2010 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: Samarium diiodide is one of the most important reducing agents available to synthetic organic chemists. The lanthanide(II) reagent acts by single-electron transfer to organic substrates leading to the formation of both radical and/or anionic intermediates. The power of the reagent arises from its versatility - samarium diiodide can be used in processes ranging from functional group conversions to elaborate carbon-carbon bond-forming cyclization sequences that result in a dramatic increase in molecular complexity. In addition, reactions involving samarium diiodide often show high stereoselectivity as samarium ions can coordinate to Lewis basic sites on substrates and can direct the stereochemical course of reactions. The ability to fine-tune the reactivity of the reagent by the use of additives and co-solvents is an additional, attractive feature. Although samarium diiodide is used extensively by organic chemists, there is still a widely held view that the reagent can be difficult to prepare and use. In addition, samarium diiodide can mediate such a wide variety of organic chemistry that potential new users are often overawed by the extensive primary literature on the reagent. The objective of this book is to provide a concise, practical guide to the reagent. Rather than being a comprehensive review of the chemistry of samarium diiodide, this user-friendly book adopts an "an all you need to know" approach to the topic. The international authors are well-known for their work with the reagent and their expertise covers current developments in new reactivity and selectivity, applications in target synthesis, co-solvent and additive effects, coordination chemistry and mechanism. The book includes the best methods for preparing and handling the reagent, how solvents, co-solvents and additives alter reactivity, the basic mechanisms of reactions, common transformations using the reagent, and emerging areas in samarium diiodide chemistry. The authors have distilled the extensive primary literature to allow the reader to quickly grasp an understanding of the reagent and its utility. The illustrative practical procedures help the reader to prepare and use the reagent in the laboratory while references from the recent literature allow readers to pursue their interest in the popular reagent. The book also contains many illustrations and chemical schemes.
