Download or read book Advances in Immunohistochemistry written by Ronald A. DeLellis and published by . This book was released on 1984 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Thioredoxin and Glutaredoxin Systems written by Jean-Pierre Jacquot and published by MDPI. This book was released on 2019-05-10 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue features recent data concerning thioredoxins and glutaredoxins from various biological systems, including bacteria, mammals, and plants. Four of the sixteen articles are review papers that deal with the regulation of development of the effect of hydrogen peroxide and the interactions between oxidants and reductants, the description of methionine sulfoxide reductases, detoxification enzymes that require thioredoxin or glutaredoxin, and the response of plants to cold stress, respectively. This is followed by eleven research articles that focus on a reductant of thioredoxin in bacteria, a thioredoxin reductase, and a variety of plant and bacterial thioredoxins, including the m, f, o, and h isoforms and their targets. Various parameters are studied, including genetic, structural, and physiological properties of these systems. The redox regulation of monodehydroascorbate reductase, aminolevulinic acid dehydratase, and cytosolic isocitrate dehydrogenase could have very important consequences in plant metabolism. Also, the properties of the mitochondrial o-type thioredoxins and their unexpected capacity to bind iron–sulfur center (ISC) structures open new developments concerning the redox mitochondrial function and possibly ISC assembly in mitochondria. The final paper discusses interesting biotechnological applications of thioredoxin for breadmaking.
Download or read book The Fourth Conference of the International Coenzyme Q10 Association written by G. P. Littarru and published by IOS Press. This book was released on 2006-07 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on coenzyme Q, this book includes topics spanning from biochemical aspects to biomedical implications and clinical use of CoQ10. It addresses the antioxidant aspects as well as the non-mitochondrial electron transport systems, and investigates coenzyme Q biosynthesis in yeast and in Caenorhabditis elegans.
Download or read book The Retina in Health and Disease written by Maurice Ptito and published by Mdpi AG. This book was released on 2021-12-27 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vision is the most important sense in higher mammals. The retina is the first step in visual processing and the window to the brain. It is not surprising that problems arising in the retina lead to moderate to severe visual impairments. We offer here a collection of reviews as well as original papers dealing with various aspects of retinal function as well as dysfunction. New approaches in retinal research are described, such as the expression and localization of the endocannabinoid system in the normal retina and the role of cannabinoid receptors that could offer new avenues of research in the development of potential treatments for retinal diseases. Moreover, new insights are offered in advancing knowledge towards the prevention and cure of visual pathologies, mainly AMD, RP, and diabetic retinopathy.
Download or read book Heat Shock Proteins in Cancer written by Stuart K. Calderwood and published by Springer Science & Business Media. This book was released on 2007-09-09 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Veterinary Vaccines and Diagnostics written by and published by Elsevier. This book was released on 1998-10-27 with total page 875 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Advances in Veterinary Medicine, derived in part from the First Veterinary Vaccines and Diagnostic Conferences, deals with vaccines, an especially active area of veterinary research and controversy.
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1982 with total page 1184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Technical Aspects of Toxicological Immunohistochemistry written by Syed A. Aziz and published by Humana Press. This book was released on 2015-12-23 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. Eleven comprehensive chapters provide pathologists and researchers in various sub-disciplines of toxicology with a comprehensive review of the methods and approaches for immunohistochemical staining in various target tissues. It explores the tissue-antigen and antibody-specific problems that may be encountered during the staining procedures and provide potential avenues for resolving various methodological issues. Special attention is paid to the latest enhancement procedures for antigen retrieval and visualization as well as image analysis and antigen quantification. Written by leading researchers in toxicology and pathology, this book is a significant resource for toxicologists and pathologists working with rodents, monkeys and aquatic animal tissues.
Download or read book Colorectal Cancer Screening written by Joseph Anderson, MD and published by Springer Science & Business Media. This book was released on 2011-04-23 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definition Colonoscopes and Narrow Band Imaging. As the text is devoted entirely to CRC screening, it features many facts, principles, guidelines and figures related to screening in an easy access format. This volume provides a complete guide to colorectal cancer screening which will be informative to the subspecialist as well as the primary care practitioner. It represents the only text that provides this up to date information about a subject that is continually changing. For the primary practitioner, information on the guidelines for screening as well as increasing patient participation is presentedd. For the subspecialist, information regarding the latest imaging techniques as well as flat adenomas and chromoendoscopy are covered. The section on the molecular changes in CRC will appeal to both groups. The text includes up to date information about colorectal screening that encompasses the entire spectrum of the topic and features photographs of polyps as well as diagrams of the morphology of polyps as well as photographs of CT colonography images. Algorithms are presented for all the suggested guidelines. Chapters are devoted to patient participation in screening and risk factors as well as new imaging technology. This useful volume explains the rationale behind screening for CRC. In addition, it covers the different screening options as well as the performance characteristics, when available in the literature, for each test. This volume will be used by the sub specialists who perform screening tests as well as primary care practitioners who refer patients to be screened for colorectal cancer.
Download or read book Carbon Ion Radiotherapy written by Hirohiko Tsujii and published by Springer Science & Business Media. This book was released on 2013-12-25 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.
Download or read book Towards New Promising Discoveries for Lung Cancer Patients A Selection of Papers from the First Joint Meeting on Lung Cancer of the FHU OncoAge Nice France and the MD Anderson Cancer Center Houston TX USA written by Paul Hofman and published by MDPI. This book was released on 2019-09-17 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue of Cancers (Basel) is mainly dedicated to selecting papers from the talks given during the first Joint Meeting on Lung Cancer (JMLC) between the MD Anderson Cancer Center (Houston, Texas USA) and the Hospital University Federation (HUF) OncoAge (University Côte d’Azur, Nice, France) (Nice, September 2018). The central theme of JMLC is to discuss new advances and exchange ideas regarding lung cancer. Notably, the talks covered different topics on new therapeutic strategies (targeted therapy and immuno-oncology), molecular and cellular biology, biomarkers, and the epidemiology of lung cancer. Special attention was also given to lung cancer in elderly patients. The articles published in this Special Issue covered subjects such as the assessment of new biomarkers and new approaches for the early detection of lung cancer, epidemiological data, and emphasized a place for the newly characterized cellular pathways in lung cancer, which opens room for therapeutic perspectives for lung cancer patients.
Download or read book Animal Andrology written by Peter J Chenoweth and published by CABI. This book was released on 2014-04-30 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding animal andrology is fundamental to optimising genetic breeding traits in domestic and wild animals. This book provides extensive coverage of male reproductive biology, discussing the essentials of sperm production, harvest and preservation before covering the applications to a range of animals including cattle, horses, pigs, small ruminants, camelids, cats and dogs, poultry and exotic species. It also examines the laboratory procedures that provide the basis of general fertility research.
Download or read book Marine Mammals Ashore written by Joseph R. Geraci and published by National Aquarium in Baltimore. This book was released on 2005 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive manual for understanding and carrying out marine mammal rescue activities for stranded seals, manatees, dolphins, whales, or sea otters.
Download or read book Allergy Immunology Secrets written by M. Eric Gershwin and published by Mosby. This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each chapter provides comprehensive coverage of all the topics necessary to pass the allergy-clinical immunology boards in the easy-to-use Secrets format. Chapters include epidemiology, pathophysiology, asthma, sinusitis, urticaria/angioedema, atopic dermatitis, anaphylaxis, food allergy/ intolerance, insect allergy, drug hypersensitivity, immunodeficiency, and systemic mast cell disease.
Download or read book Proceedings of the 1st International Conference for Health Research BRIN ICHR 2022 written by Ika Nurlaila and published by Springer Nature. This book was released on 2023-04-02 with total page 978 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access book. The National Research and Innovation Agency (Acronymized in Bahasa as BRIN, Badan Riset and Inovasi Nasional), the Republic of Indonesia was launched in 2021 and has been the only one of Indonesia authorized research institution since. The Agency embodies throughout department and non-department research bodies in Indonesia and answers and thus responsible directly to the President of Indonesia. Despite its juvenile age, BRIN is in a tight competition with urgencies of untangling unresolved issues in various aspects in collective life as a nation and a state spanning socioeconomic and culture to medicine and its translational derivatives. To function as effectively as expected, BRIN has launched 12 research organizations with each is accountable for a specific research field as reflected by the expertise of the pertinent researchers. Among those, Research Organization for Health was established as an answer to the major challenge of overcoming national burdens which are holistically captured as the roadmaps of SDG’s Indonesia where Health stands specially as the top three priority and regarded as Good Health-Wellbeing. It is clear that what have been produced through long chain of processes in the research chambers must be driven forward and translated accordingly to reach downstream utilizations in such a way that the good health and well-being are reachable in any levels. As to manifesting these goals into realization, knowledge sharing is deemed to be a plausible vehicle. This enables disseminations of most current research projects related to health across research institution, regionally or globally. Therefore, we see the need to organize our very first international conference that is, further, set as one of our annual events with contemporary umbrella themes. We welcome researchers, scholars, and practitioners in health and health-related fields to share their insightful research results in our conference. The general objective of BRIN’s 1st International Conference for Health (ICHR) is to facilitate dissemination and exchange of most recent progresses made across research institutions and to promote prospectus multi-nationals and or multi-institutional collaborations to achieve the good-health and well-being.
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 1628 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
