Download or read book Somitogenesis Part 1 written by and published by Academic Press. This book was released on 1999-12-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters contained in this two-volume set provide a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis - the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) as well as those already well established for classical experimental embryological and cell biological studies (amphibians, avian). The wide variety of experimental approaches to somitogenesis that are presented in these volumes will leave the reader with a broad perspective on how current research in somitogenesis is helping to solve fundamental questions in vertebrate development and morphogenesis.Key Features:* Novel transcriptional mechanisms that control repetitive pattern formation* Wide scale genetic screens for mutations affecting somitogenesis* Molecular/genetic control of pattern and tissue formation during somitogenesis* Transplantation of mouse embryo somites* Classical embryological approaches and concepts* Evolutionary perspectives on somitogenesis

Download or read book Somitogenesis written by Miguel Maroto and published by Springer Science & Business Media. This book was released on 2008-12-10 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will be of interest to scientists working in the fields of cell and developmental biology. The chapters cover topics that capture the spirit of this dynamic discipline by integrating contemporary research with the classical embryological literature.

Download or read book The Origin and Fate of Somites written by North Atlantic Treaty Organization. Scientific Affairs Division and published by IOS Press. This book was released on 2001 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text investigates advances in the field of sommites and integrates them into the accumulated knowledge of how sommites form and differentiate. Although the book focuses on the formation and patterning of somites it will encompass a broader life history of a somite. Topics include events attending gastrulation, which foreshadow somite formation, to the subsequent contributions that somites make to neighbouring regions such as musculature, limbs and axial skeleton. There is also a discussion of the origins of cells that eventually give rise to somites. This book brings together investigators from NATO and NATO partner countries who are employing both classical and molecular approaches to the analysis of somitogenesis.

Download or read book Somitogenesis Part 2 written by and published by Elsevier. This book was released on 2000-01-10 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters contained in this two-volume set provide a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis - the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) as well as those already well established for classical experimental embryological and cell biological studies (amphibians, avian). The wide variety of experimental approaches to somitogenesis that are presented in these volumes will leave the reader with a broad perspective on how current research in somitogenesis is helping to solve fundamental questions in vertebrate development and morphogenesis. - Novel transcriptional mechanisms that control repetitive pattern formation - Wide-scale genetic screens for mutations affecting somitogenesis - Molecular/genetic control of pattern and tissue formation during somitogenesis - Transplantation of mouse embryo somites - Classical embryological approaches and concepts - Evolutionary perspectives on somitogenesis

Download or read book Somitogenesis written by Miguel Maroto and published by Springer. This book was released on 2010-11-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will be of interest to scientists working in the fields of cell and developmental biology. The chapters cover topics that capture the spirit of this dynamic discipline by integrating contemporary research with the classical embryological literature.

Download or read book The Roles of Notch Signaling During Xenopus Somitogenesis written by Wui-Chuong Jen and published by . This book was released on 1999 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Somitogenesis written by and published by Academic Press. This book was released on 1999-12-07 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters contained in this two-volume set provide a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis - the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) as well as those already well established for classical experimental embryological and cell biological studies (amphibians, avian). The wide variety of experimental approaches to somitogenesis that are presented in these volumes will leave the reader with a broad perspective on how current research in somitogenesis is helping to solve fundamental questions in vertebrate development and morphogenesis. Key Features: * Novel transcriptional mechanisms that control repetitive pattern formation * Wide scale genetic screens for mutations affecting somitogenesis * Molecular/genetic control of pattern and tissue formation during somitogenesis * Transplantation of mouse embryo somites * Classical embryological approaches and concepts * Evolutionary perspectives on somitogenesis

Download or read book Somites in Developing Embryos written by Ruth Bellairs and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Somite development is a unique and important topic; unique because somitic mesoderm is the first tissue to become segmented, important because the somites - once established - exert a profound influence on other seg mental structures which form later. Somite development is of interest at a number of levels. In one aspect, demarcation of a specific number of somites and size regulation, it is a particularly intriguing example of embryonic pattern formation, 'especially in vew of its possible relation to homoeobox-controlled segmentation in insects. At another level, somite development has long been studied by compara tive anatomists, but only recently has new light been thrown on such sub jects as segmentation of the head, proposed in the 18th century by Goethe and now a live issue for developmental biologists. Somit es are simple when they first appear, but very complex structures arise from them. These include the vertebrae and the axial and other muscles and consequently there is a wealth of morphogenetic problems to be explored. Sometimes their morphogenesis is disturbed, by genetic or environ mental factors, and there are many clinical conditions which arise as a result.

Download or read book Dissecting the Roles of Lunatic Fringe in the Process of Somitogenesis written by John D. Franklin and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Somitogenesis is the formation of somites from the presomitic mesoderm and is a highly controlled and sequential process. Somites gives rise to the vertebrae, ribs, and skin and muscle of the back, thus regulation of this process is crucial for normal development. Recent data have suggested that a "segmentation clock" regulates the timing of somite formation. Several models suggest that transcriptional oscillation of key genes in the Notch signaling pathway is important in the clock. This study focuses on the Notch signaling pathway member Lunatic fringe (Lfng) which modifies the extracellular domain of the Notch receptor. Lfng activity is crucial for the proper development of somites as it is involved in both the clock regulation of somite formation and in the A/P patterning of the somites. Lfng is known to be expressed in two distinct regions of the presomitic mesoderm and it is the aim of this study to differentiate the roles and actions of Lfng in these processes. It is known that Lfng expression in the clock is controlled by different regulatory elements than those controlling its expression during A/P patterning. We first asked if Lfng activity plays a role in regulating its own expression by examining the expression of an Lfng/GFP reporter transgene on a Lfng null background. Expression was seen only in the anterior presomitic mesoderm where somites are being patterned in Lfng null embryos. In contrast, no expression was seen in the 'clock' region of the presomitic mesoderm. This supports the theory of distinct roles for Lfng in the A/P patterning of somites in the anterior presomitic mesoderm and in the segmentation clock in the more posterior presomitic mesoderm. Further, it suggests a model in which Lfng inhibition of Notch is required for its own expression in the clock. To analyze the roles Lfng plays in the clock and in A/P patterning, skeletal defects of mice were examined comparing mice that had disrupted Lfng expression in the segmentation clock only (LfngFCE1del) to those which were completely null for Lfng. We found that the skeletal defects in mice which had Lfng disrupted in the clock were less severe than those seen in mice that lacked Lfng in both the clock and A/P patterning. The intermediate phenotype of LfngFCE1del mice suggests that Lfng is important in both roles. Furthermore, the ribs of LfngFCE1del animals were more severely affected than the tails of the same animals indicating that thoracic somites are more sensitive to Notch oscillation than tail somites. Finally, in situ hybridizations are being performed to elucidate the involvement of Lfng in regulating the transcription of other Notch pathway members in the clock. Preliminary data suggests Notch1 levels are largely unaffected in the absence of Lfng in the clock.

Download or read book FGF Signalling in Vertebrate Development written by Mary Elizabeth Pownall and published by Morgan & Claypool Publishers. This book was released on 2010 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a printed version of a work that appears in the Colloquium Digital Library of Life Sciences. Colloquium titles cover all of cell and molecular biology and biomedicine, including the neurosciences, from the advanced undergraduate and graduate level up to the post-graduate and practicing researcher level. They offer concise, original presentations of important research and development topics, published quickly, in digital and print formats. For more information, visit www.morganclaypool.com --Book Jacket.

Download or read book The Neural Crest written by Nicole Le Douarin and published by Cambridge University Press. This book was released on 1999-11-28 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Download or read book Fish Development and Genetics written by Zhiyuan Gong and published by World Scientific. This book was released on 2004 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: The zebrafish is the most important fish model in developmental andgenetic analyses. This book contains 19 review articles covering abroad spectrum of topics, from development to genetic tools. Thecontents range from early development, the role of maternal factorsand gastrulation, to tissue differentiation and organogenesis, such asdevelopment of the organizer, notochord, floor plate, nervous system, somites, muscle, skeleton and endoderm

Download or read book Vertebrate Limb and Somite Morphogenesis written by British Society for Developmental Biology and published by CUP Archive. This book was released on 1977-12-22 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Somitogenesis written by and published by Academic Press. This book was released on 2000-01-06 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters contained in this two-volume set provide a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis - the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) as well as those already well established for classical experimental embryological and cell biological studies (amphibians, avian). The wide variety of experimental approaches to somitogenesis that are presented in these volumes will leave the reader with a broad perspective on how current research in somitogenesis is helping to solve fundamental questions in vertebrate development and morphogenesis. Novel transcriptional mechanisms that control repetitive pattern formation Wide-scale genetic screens for mutations affecting somitogenesis Molecular/genetic control of pattern and tissue formation during somitogenesis Transplantation of mouse embryo somites Classical embryological approaches and concepts Evolutionary perspectives on somitogenesis

Download or read book The Genetics and Development of Scoliosis written by Kenro Kusumi and published by Springer Science & Business Media. This book was released on 2009-12-15 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental genetic studies of the spine and linkage and family-based association studies have led to recent advances in understanding the genetic etiology of idiopathic, neuromuscular, and congenital forms of scoliosis. The book is written by leaders in genetic and developmental research on scoliosis and developmental studies of the spine.

Download or read book Models of Biological Pattern Formation written by Hans Meinhardt and published by . This book was released on 1982 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Current Topics in Developmental Biology written by and published by Academic Press. This book was released on 1998-02-03 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Series provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. This year marks a major milestone for the Series as it completes its thirtieth year of publication, making it the longest-running forum for contemporary issues in developmental biology.