Download or read book Some Recent Applications of Mass Spectrometry to Biochemistry written by Biochemical Society. Techniques Group and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Some Recent Applications of Mass Spectrometry to Biochemistry written by Biochemical Society and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Medical Applications of Mass Spectrometry written by Karoly Vekey and published by Elsevier. This book was released on 2011-08-11 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging. * Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.

Download or read book Applications of Modern Mass Spectrometry Volume 1 written by Atta-ur-Rahman and published by Bentham Science Publishers. This book was released on 2020-07-02 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Modern Mass Spectrometry covers the latest advances in the use of mass spectrometry in scientific research. The series attempts to present readers information on the broad range of mass spectrometry techniques and configurations, data analysis and practical applications. Each volume contains contributions from eminent researchers who present their findings in an easy to read format. The multidisciplinary nature of the works presented in each volume of this book series make it a valuable reference on mass spectrometry to academic researchers and industrial R&D specialists in applied sciences, biochemistry, life sciences and allied fields. The first volume of the series presents 5 reviews: - Applications of mass spectrometry for the determination of the microbial crude protein synthesis in ruminants - Qualitative and quantitative LC-MS analysis in food proteins and peptides - Chemometrics as a powerful and complementary tool for mass spectrometry applications in life sciences - Recent developments of allied techniques of qualitative analysis of heavy metal ions in aqueous solutions with special reference to modern mass spectrometry - New techniques and methods in explosive analysis.

Download or read book Biochemical Applications of Mass Spectrometry written by George B. Waller and published by . This book was released on 1972 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2011-02-14 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a balanced mixture of practice-oriented information and theoretical background as well as numerous references, clear illustrations, and useful data tables. Problems and solutions are accessible via a special website. This new edition has been completely revised and extended; it now includes three new chapters on tandem mass spectrometry, interfaces for sampling at atmospheric pressure, and inorganic mass spectrometry.

Download or read book Recent Developments in Mass Spectrometry in Biochemistry and Medicine written by Alberto Frigerio and published by Springer. This book was released on 1979-09 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers collected in this volume were presented at the 5th International Symposium on Mass Spectrometry in Biochemistry and Medicine held at Rimini, Italy, in June 1978. This meeting was organized by the Italian Group for Mass Spectrometry in Biochemistry and Medicine, which was founded in Milan, Italy, in 1975 by researchers working in different fields (chemistry, pharmacology, medicine, biology). I wish to thank Mrs. Anna Bernard, Mrs. Donata Castoldi and Miss Vanna Pistotti for their invaluable technical assistance and countless eff. orts in the preparation of this volume. Alberto Frigerio Milan, March, 1979 v Contents The Place of Mass Spectrometry in Drug Metabolism Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 A. Benakis In Vitro and in vivo Studies on the Metabolism of Dibenzo/c,f 7-/-1,2 7 Diazepine ********. ********* 9 A. Frigerio, P~ Negrini, D~ Rotilio, A. De Pascale and E. Rossi Gas Chromatographic-Mass Spectrometric Identification of Urinary Metabolites of Propildazine in Rat 27 L. Simonotti, R. Colombo and G. Pifferi Mass Spectrometric Characterization of Sydnocarb ~ and its Major Metabolites in Rat ***************** 43 J. Tamas, M. Polgar, G. Czira and L. Vereczkey Metabolism of an Aryloxy Beta Blocking Drug 53 G. L. Passetti, E. Grassi and A. Trebbi Isolation and Identification of the Chloroform Soluble Urinary Metabolites of Suloctidil in Man . ****. . ** 69 R. Roncucci, W. Cautreels, M. Martens, C. Gillet, K. Debast and G. Lambelin Are Stable Sulfenic Acids Possible Metabolites of Suloctidil? . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 W. Cautreels, M. Martens, R. Roncucci, C. Gillet, K. Debast and G.

Download or read book Recent Developments in Mass Spectrometry in Biochemistry and Medicine written by Alberto Frigerio and published by Springer. This book was released on 2011-11-08 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: The papers collected in this volume were presented at the 4th International Symposium on Mass Spectrometry in Biochemistry and Medicine held at Riva del Garda, Italy in June 1977. This meeting was organised by the Italian Group for Mass Spectrometry in Biochemistry and Medicine. The group was founded in Milan, Italy, in 1975 by researchers working in different fields (chemistry, pharmacology, medicine, biology). The aim of the symposium was to bring together people working in different branches of mass spectrometry for mutual discussion, exchange of ideas and experience. I wish to thank Mrs. Judy Baggot, Mrs. Donata Castoldi and Miss Vanna Pistotti for their invaluable technical assistance and countless efforts in the preparation of this volume. Alberto Frigerio Milan, January, 1978 v CONTENTS Newer Aspects of the Biotransformation of Carbamazepine: Structural Characterization of Highly Polar Metabolites • • • • 1 W. J. Richter, P. Kriemler and J. W. Faigle Distribution in Brain Areas of Carbamazepine and Carbamazepine-lO,ll-epoxide in 6-Hydroxydopamine Pretreated Rats 15 C. Pantarotto, V. Crunelli, A. Quattrone, P. Negrini, A. Frigerio and R. Samanin Specific Ion Detection of Aryloxy Beta Blocking Drugs for Metabolic Fate Determinations Applications to Alprenolol in Rats and Dogs 29 T. Walle and K. Walle The Use of GC-MS in Perinatal Pharmacology: The Metabolism and Pharmacokinetics of Analgesic Drugs in Mothers and Their Babies • • • • • • • • 49 J. Caldwell, L. J. Notarianni and L. A.

Download or read book Mass Spectrometry written by Marek Smoluch and published by John Wiley & Sons. This book was released on 2019-06-17 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a comprehensive description of mass spectrometry basics, applications, and perspectives Mass spectrometry is a modern analytical technique, allowing for fast and ultrasensitive detection and identification of chemical species. It can serve for analysis of narcotics, counterfeit medicines, components of explosives, but also in clinical chemistry, forensic research and anti-doping analysis, for identification of clinically relevant molecules as biomarkers of various diseases. This book describes everything readers need to know about mass spectrometry—from the instrumentation to the theory and applications. It looks at all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS (paying special attention to various methodologies and data interpretation). It also contains a list of key terms for easier and faster understanding of the material by newcomers to the subject and test questions to assist lecturers. Knowing how crucial it is for young researchers to fully understand both the power of mass spectrometry and the importance of other complementary methodologies, Mass Spectrometry: An Applied Approach teaches that it should be used in conjunction with other techniques such as NMR, pharmacological tests, structural identification, molecular biology, in order to reveal the true function(s) of the identified molecule. Provides a description of mass spectrometry basics, applications and perspectives of the technique Oriented to a broad audience with limited or basic knowledge in mass spectrometry instrumentation, theory, and its applications in order to enhance their competence in this field Covers all aspects of mass spectrometry, including inorganic, organic, forensic, and biological MS with special attention to application of various methodologies and data interpretation Includes a list of key terms, and test questions, for easier and faster understanding of the material Mass Spectrometry: An Applied Approach is highly recommended for advanced students, young scientists, and anyone involved in a field that utilizes the technique.

Download or read book Liquid Chromatography Mass Spectrometry written by Alfred L. Yergey and published by Springer Science & Business Media. This book was released on 1990-01-31 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended both to be an introduction to techniques and applications of liquid chromatography/mass spectrometry and to serve as a reference for future workers. When we undertook its writing, we chose not to cover the field, particularly applications, exhaustively. Rather we wished to produce a book that would be of use to people just beginning to use the technique as well as to more advanced practitioners. In this regard, we have sought to highlight techniques and applications that are of current importance, while not neglecting descriptions of approaches that may be of significance in the future. We hope that we have succeeded in this. At the same time we hope that the bibliography, with indexes classified by author and title, will make this book of value to those who may disagree with our emphasis. ACKNOWLEDGMENTS. One of us (C. G. E. ) wishes to acknowledge the en couragment of Professor J. A. McCloskey in undertaking this project. All four of us are grateful for the continuous and expert assistance of V. A. Edmonds in the preparation of the Bibliography. Alfred L. Y ergey Bethesda, Maryland Charles G. Edmonds Richland, Washington lvor A. S. Lewis London, England Marvin L. Vestal Houston, Texas v Contents 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . 1 . . . . . . . . . . . 2. Direct Liquid Introduction Interfaces . . . . . . . . . . 5 . . . 2. 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 2. 2. Operating Principles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. 3. Specific DLI Interfaces . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 2. 3. 1. Capillary Inlets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 2. 3. 2. Diaphragm Interfaces . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 2. 3. 3. Nebulizing Interfaces . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Download or read book Mass Spectrometry in Biophysics written by Igor A. Kaltashov and published by John Wiley & Sons. This book was released on 2005-05-06 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first systematic summary of biophysical mass spectrometrytechniques Recent advances in mass spectrometry (MS) have pushed the frontiersof analytical chemistry into the biophysical laboratory. As aresult, the biophysical community's acceptance of MS-based methods,used to study protein higher-order structure and dynamics, hasaccelerated the expansion of biophysical MS. Despite this growing trend, until now no single text has presentedthe full array of MS-based experimental techniques and strategiesfor biophysics. Mass Spectrometry in Biophysics expertly closesthis gap in the literature. Covering the theoretical background and technical aspects of eachmethod, this much-needed reference offers an unparalleled overviewof the current state of biophysical MS. Mass Spectrometry inBiophysics begins with a helpful discussion of general biophysicalconcepts and MS-related techniques. Subsequent chaptersaddress: * Modern spectrometric hardware * High-order structure and dynamics as probed by various MS-basedmethods * Techniques used to study structure and behavior of non-nativeprotein states that become populated under denaturingconditions * Kinetic aspects of protein folding and enzyme catalysis * MS-based methods used to extract quantitative information onprotein-ligand interactions * Relation of MS-based techniques to other experimental tools * Biomolecular properties in the gas phase Fully referenced and containing a helpful appendix on the physicsof electrospray mass spectrometry, Mass Spectrometry in Biophysicsalso offers a compelling look at the current challenges facingbiomolecular MS and the potential applications that will likelyshape its future.

Download or read book Clinical Applications of Mass Spectrometry in Biomolecular Analysis written by Uttam Garg and published by Springer Nature. This book was released on 2022-09-20 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and limited need for specialized reagents. These techniques are essential in laboratory fields including endocrinology, biochemical genetics, drug analysis, proteomics, and pathogen identification. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols, Second Edition is an ideal resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.

Download or read book Mass Spectrometry written by Edmond de Hoffmann and published by John Wiley & Sons. This book was released on 2013-04-03 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analysers and detectors. Tandem mass spectrometry is introduced early on and then developed in more detail in a later chapter. Emphasis is placed throughout the text on optimal utilisation conditions. Various fragmentation patterns are described together with analytical information that derives from the mass spectra. This new edition has been thoroughly revised and updated and has been redesigned to give the book a more contemporary look. As with previous editions it contains numerous examples, references and a series of exercises of increasing difficulty to encourage student understanding. Updates include: Increased coverage of MALDI and ESI, more detailed description of time of flight spectrometers, new material on isotope ratio mass spectrometry, and an expanded range of applications. Mass Spectrometry, Third Edition is an invaluable resource for all undergraduate and postgraduate students using this technique in departments of chemistry, biochemistry, medicine, pharmacology, agriculture, material science and food science. It is also of interest for researchers looking for an overview of the latest techniques and developments.

Download or read book Mass Spectrometry in Biomolecular Sciences written by Richard M. Caprioli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 531 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry in the Biological Sciences covers the most recent technological and applied developments in the area, including both ionization techniques and ion analysis. It introduces and reviews some of the newer ionization methods, describes the major instrumentation involved in mass analysis, and presents the scope of the technology in biology, medicine, and environmental science. Specific examples are given for a number of topics. It also deals with recent achievements in the on-line combination of separation techniques such as gas chromatography, liquid chromatography, and supercritical fluid technology.

Download or read book Selected Topics in Mass Spectrometry in the Biomolecular Sciences written by Richard M. Caprioli and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many fundamental aspects of the methods used in mass spectrometry are here presented by outstanding scientists, with reference to very recent developments. The principles and applications of electrospray, ion spray and MALDI ionization technique are presented, together with optimised GC/MS interfacing systems and tools for quantitative analysis. A comprehensive treatment of modern instrumentation for mass analysis and detection is also included. The major part of the book deals with bioanalytical applications to peptides, proteins, oligonucleotides, polysaccharides, lipids and plant metabolites. Several papers are devoted to the evaluation of adduct formation between DNA and carcinogens. Environmental applications are also included, with examples of some specific cases. Fundamentals and applications are treated with the same degree of depth: the first two parts of the book therefore provide a basis for the understanding of the biomolecular applications section. Audience: Ideal for advanced graduate students of chemistry who have learned some basic mass spectrometry. Also useful for Ph.D. students in chemistry, biology and medicine. Of value to researchers in academic and industrial laboratories.

Download or read book Mass Spectrometry in Chemical Biology written by Norberto Peporine Lopes and published by Royal Society of Chemistry. This book was released on 2017-11-16 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass spectrometry is one of the most widespread technologies in chemistry and has been increasingly used in biology with the rise of omics sciences. This book summarizes some important methodological approaches in mass spectrometry and applications in the field of chemical biology. The core chapters build on basic concepts introduced in the opening chapter and explore established fields such as high throughput screening, proteomics and metabolomics. Emerging applications of mass spectrometry in elucidating biosynthetic pathways, enzyme mechanisms and protein-protein interactions are then presented. Connections between these diverse research fields are highlighted throughout. The book concludes with a discussion of databases and future perspectives. This book will be a useful tool to early chemical biology researchers wishing to incorporate mass spectrometry as a tool in their research.

Download or read book Biological Mass Spectrometry written by A.L. Burlingame and published by Gulf Professional Publishing. This book was released on 2005-11-28 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes and integrates the techniques of many advances in both chromatographic and mass spectrometric technologies. This book also covers various biophysical applications, such as H/D exchange for study of conformations, protein-protein and protein-metal and ligand interactions. It also describes atto-to-zepto-mole quantitation of 14C and 3H.